|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Study on the Control of Tobacco Black Shank by Using Dry Mycelium of Penicillium Chrysogenum显示文摘 | Changliang Xu Rong Zeng Chunsheng Ruan Xiaoxia Wang Kaibao Xia George McBride Jianpeng Luo Suiyun Chen | 2010 | Journal of Life Sciences2010，4，1： | 12 |
| 2 | 睾酮缺乏症的诊断和治疗显示文摘近些年来,随着睾酮缺乏症(TD)发病率的上升、新药的不断开发、以及商业推广的深入,睾酮替代疗法(TST)的临床应用显著增多。然而,关于睾酮缺乏症的诊断标准以及TST的应用和监测,仍然不是很明确。此种现象主要源于睾酮的多重作用靶点。在人体内,睾酮参与了很多生理过程的调节,同时睾酮的表达水平也受很多疾病及药物的影响。因此,睾酮缺乏症的临床症状和体征具有多样性和非特异性,也就增加了睾酮缺乏症的诊断难度,尤其在老年人群中。临床上,关于血清睾酮水平的检测也存在争议,不同实验室之间存在一定的差异,因此也很难界定睾酮水平的诊断标准。很多医学专业组织试图制定睾酮缺乏症的诊断指南,但彼此间很难达成统一。另外,临床使用的睾酮制剂也层出不穷,相应的TST治疗方案也像TD的诊断标准一样不断更新和变化。临床上,随着TST的不断推进,专科医师必须不断更新对于TD和HTST的了解和治疗及应用。本文旨在阐述TD的最新概念及其诊断和治疗的新进展。 | James A McBride Culley C Carson Robert M Coward | 2015 | Asian Journal of Andrology2015，17，2： | 5 |
| 3 | Methane Emissions from Grazing Holstein-Friesian Heifers at Different Ages Estimated Using the Sulfur Hexafluoride Tracer Technique显示文摘动物和日粮因素对牛肠道甲烷排放量影响的相关研究已经很普遍,但是关于放牧青年奶牛的甲烷排放量的可参考数据较少。本研究评估了荷斯坦奶牛在多年生黑麦草草地放牧时的生理状态对甲烷排放量的影响,分别进行了以下两个试验:试验1从2011年5月开始,为期11个星期,试验2从2011年8月开始,为期10个星期。在每个试验中,将荷斯坦奶牛分成三个处理组(每组12头),分别由小牛犊、一岁的母牛犊和妊娠母牛组成(平均年龄分别为8.5、14.5和20.5月龄)。在每个试验的最后一个星期利用六氟化硫示踪技术预估每头牛的甲烷排放量。干物质摄入量由代谢能需要量除以牧草中的代谢能含量计算而得。正如预期一样,活体重随年龄的增加而增加(P<0.001),然而试验1中三个分组的体增重没有差异,试验2中的体增重随着年龄增加有不同程度的减少(P<0.001)。在试验1中,妊娠母牛高于小牛犊的甲烷排放量(P<0.001),而一岁母牛犊的甲烷排放量最高(g·d^(-1))。当用单位活体重、干物质摄入量和总能摄入量表示甲烷排放量时,一岁母牛犊比小牛犊和妊娠母牛的排放速率更高(P<0.001)。在试验2中,甲烷排放量(g·d^(-1))随着年龄增加呈线性上升(P<0.001),但是这种差异在一岁母牛犊和妊娠母牛中并不显著。妊娠母牛的甲烷/活体重的比值低于另外两组(P<0.001),小牛犊的总能摄入量中甲烷能量输出的比值低于一岁母牛犊和妊娠母牛(P<0.05)。根据所有数据建立甲烷排放量的预测方程。所有关系均为显著(P<0.001),R2值的分布范围为0.630~0.682。这些模型表明:每增加1 kg活体重,甲烷排放量增加0.252 g·d^(-1);每增加1 kg·d^(-1)干物质摄入量,甲烷排放量增加14.9 g·d^(-1);每增加1 MJ·d^(-1)总能摄入量,甲烷能量输出增加0.046 MJ·d^(-1)。当实际甲烷排放量不可测时,这些结果为我们提供了预估放牧母牛甲烷排放量的另一种方法。 | Steven J. Morrisonn Judith McBride Alan W. Gordon Alastair R. G. Wylie Tianhai Yan | 2017 | Engineering2017，3，5： | 4 |
| 4 | Health risk from heavy metals via consumption of food crops in the vicinity of Dabaoshan mine, South China显示文摘 | Ping Zhuang Murray B. McBride Hanping Xia Ningyu Li Zhian Li | 2008 | Science of the Total Environment2008，，5： | 3 |
| 5 | Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders显示文摘 | Elaine Y. Hsiao Sara W. McBride Sophia Hsien Gil Sharon Embriette R. Hyde Tyler McCue Julian A. Codelli Janet Chow Sarah E. Reisman Joseph F. Petrosino Paul H. Patterson Sarkis K. Mazmanian | 2013 | Cell2013，，7： | 3 |
| 6 | Evaluation of the safety and effectiveness of direct oral anticoagulants and low molecular weight heparin in gastrointestinal cancer-associated venous thromboembolism显示文摘BACKGROUND Gastrointestinal cancer(GICA)is associated with a higher incidence of venous thromboembolism(VTE)compared to other solid tumors,moreover,recurrent VTE and major bleeding(MB)complications during anticoagulation treatment have an associated increase rate.GICA-VTE remains a challenging clinical scenario with MB concerns for utilization of direct oral anticoagulants(DOAC),especially with active cancer therapies.AIM To evaluate patient risk factors,effectiveness(VTE)and safety(MB)of DOACs and low molecular weight heparin(LMWH)in patients with active GICA-VTE.METHODS A retrospective chart review of patients receiving DOACs and LMWH with GICA and symptomatic or incidental VTE treated at comprehensive cancer center from November 2013 to February 2017 was performed.Inclusion criteria included active GI cancer diagnosed at any stage or treatment+/-6 mo of VTE diagnosis,whom were prescribed 6 mo or more of DOACs or LMWH.The Chi-squared test was used for overall and the Fisher exact test for pairwise comparisons of the proportions of patients experiencing recurrent VTE and MB events.Odds ratios were used to compare the relative odds of the occurrence of the outcome given exposure to the risk factor.RESULTS A total of 144 patients were prescribed anticoagulation,in which 106 fulfilled inclusion criteria apixaban(27.3%),rivaroxaban(34.9%)and enoxaparin(37.7%),and 38 were excluded.Patients median age was 66.5 years at GICA diagnosis and 67 years at CAVTE event,with 62%males,80%Caucasian,70%stage IV,pancreatic cancer(40.5%),30%Khorana Score(≥3 points),and 43.5%on active chemotherapy.Sixty-four percent of patients completed anticoagulation therapy(range 1 to 43 mo).Recurrent VTE at 6 mo was noted in 7.5%(n=3),6.8%(n=2)and 2.7%(n=1)of patients on enoxaparin,apixaban and rivaroxaban,respectively(all P=NS).MB at 6 mo were 5%(n=2)for enoxaparin,6.8%(n=2)for apixaban and 21.6%(n=8)for rivaroxaban(overall P=0.048;vs LMWH P=0.0423;all other P=NS).Significant predictors of a primary or secondary outcome for all anticoagulation therapies included:Active systemic treatment(OR=5.1,95%CI:1.3-19.3),high Khorana Score[≥3 points](OR=5.5,95%CI:1.7-17.1),active smoker(OR=6.7,95%CI:2.1-21.0),pancreatic cancer(OR=6.8,95%CI:1.9-23.2),and stage IV disease(OR=9.9,95%CI:1.2-79.1).CONCLUSION Rivaroxaban compared to apixaban and enoxaparin had a significantly higher risk of MB on GICA-VTE patients with equivocal efficacy. | Alejandro Recio-Boiles Sumana Veeravelli Jessica Vondrak Hani M Babiker Aaron J Scott Rachna T Shroff Hitendra Patel Emad Elquza Ali McBride | 2019 | World Journal of Gastrointestinal Oncology2019，11，10： | 3 |
| 7 | Evaluation of Tower and Candle rapeseed (canola) meal and Brono wski rapeseed protein concentrate as protein supplements in practical dry diets for juvenile Chinook salmon ( Oncorhynchus tshaurytscha) 显示文摘 | Higgs D A Mcbride J R Markert J R | | Aquaculture0，19，： | 2 |
| 8 | Health risk from heavy metals via consumption of food crops in the vicinity of Dabaoshan mine, South China显示文摘 | Ping Zhuang Murray B. McBride Hanping Xia Ningyu Li Zhian Li | 2008 | Science of the Total Environment2008，，5： | 2 |
| 9 | 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines显示文摘 | Neil J. Stone Jennifer G. Robinson Alice H. Lichtenstein C. Noel Bairey Merz Conrad B. Blum Robert H. Eckel Anne C. Goldberg David Gordon Daniel Levy Donald M. Lloyd-Jones Patrick McBride J. Sanford Schwartz Susan T. Shero Sidney C. Smith Karol Watson Pet | 2014 | Circulation (_suppl_ Suppl)2014，，25： | 2 |
| 10 | 2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines显示文摘 | Clyde W. Yancy Mariell Jessup Biykem Bozkurt Javed Butler Donald E. Casey Mark H. Drazner Gregg C. Fonarow Stephen A. Geraci Tamara Horwich James L. Januzzi Maryl R. Johnson Edward K. Kasper Wayne C. Levy Frederick A. Masoudi Patrick E. McBride John J.V. | 2013 | Circulation2013，，16： | 2 |
| 11 | Metal mobility at an old, heavily loaded sludge application site显示文摘 | Brian K. Richards Tammo S. Steenhuis John H. Peverly Murray B. McBride | 1998 | Environmental Pollution1998，，3： | 2 |
| 12 | Mitochondria: More Than Just a Powerhouse显示文摘 | Heidi M. McBride Margaret Neuspiel Sylwia Wasiak | 2006 | Current Biology2006，，14： | 2 |
| 13 | 果岭上14种匍匐剪股颖的表现(英文)显示文摘比较了在果岭区匍匐剪股颖的 6个多枝条密度品种和 8个标准品种在不同时期 ,分蘖数、根干重、非结构性糖含量的变化规律。得出了以下结论 :1)品种之间的分蘖数在 7月差异显著 (P≤ 0 .0 5 ) ,但 4月、10月不显著 ,2 )品种之间根重无区 ,但春季 6个高枝条密度品种的根重比 8个标准品种的要重 ;随修剪高度降低 ,根重减少。 3)在 18个采样日期中只有两个时期的非结结构性糖的含量显著不同 ,即在相对高温期间高枝条密度品种较标准品种非结区性糖的积累量要少。 | 王代军 Karl Danneberger Patty Sweeny Michael McBride | 2001 | 草原与草坪2001，21，4： | 2 |
| 14 | The ZBTB24-CDCA7 axis regulates HELLS enrichment at centromeric satellite repeats to facilitate DNA methylation显示文摘Dear Editor,Immunodeficiency,centromeric instability,and facial anomalies(ICF)syndrome is a rare autosomal recessive disorder characterized by antibody deficiency,facial dysmorphism,failure to thrive,and mental retardation.Patients with ICF syndrome suffer from recurrent and often fatal infections in early childhood.A hallmark of ICF syndrome is loss of DNA methylation in special genomic regions,most notably satellite repeats at centromeric regions,which leads to heterochromatin decondensation and chromosomal abnormalities in lymphocytes(Ehrlich et al.,2008). | Swanand Hardikar Zhengzhou Ying Yang Zeng Hongbo Zhao Bigang Liu Nicolas Veland Kevin McBride Xiaodong Cheng Taiping Chen | 2020 | Protein & Cell2020，11，3： | 2 |
| 15 | Multinational enterprise strategy, foreign direct investment and economic development: the case of the Hungarian banking industry显示文摘 | Yusaf H. Akbar J.Brad McBride | 2003 | Journal of World Business2003，，1： | 2 |
| 16 | Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death 显示文摘 | McBride A G Borutaite V Brown G C | 1999 | Biochim Biophys Acta1999，1454，3： | 1 |
| 17 | Child characteristics, parenting stress, and parental involvement: Fathers versus mothers 显示文摘 | McBride BA Schoppe SJ Rane TR | 2002 | Journal of Marriage and Family2002，64，4： | 1 |
| 18 | Variants in DNA double-strand break repair genes and breast cancer susceptibility显示文摘 | Kuschel B Auranen A McBride S | 2002 | Hum Mol Genet2002，11，12： | 1 |
| 19 | Phosphorus utilization and environmental and economic Implications of reducing phosphorus pollution from ontario dairy cows显示文摘 | Kebreab E Odongo N E McBride B W | 2008 | J Dairy Sci2008，91，： | 1 |
| 20 | Cytokine balance and inmmunosuppressive change at cardiac surgery 显示文摘 | Mcbride WT Armstrong MA | 1995 | Br J Anesth1995，75，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员