|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ten years of sorafenib in hepatocellular carcinoma: Are there any predictive and/or prognostic markers?显示文摘Sorafenib has been considered the standard of care for patients with advanced unresectable hepatocellular carcinoma(HCC) since 2007 and numerous studieshave investigated the role of markers involved in the angiogenesis process at both the expression and genetic level and clinical aspect. What results have ten years of research produced? Several clinical and biological markers are associated with prognosis. The most interesting clinical parameters are adverse events, Barcelona Clinic Liver Cancer stage, and macroscopic vascular invasion, while several single nucleotide polymorphisms and plasma angiopoietin-2 levels represent the most promising biological biomarkers. A recent pooled analysis of two phase III randomized trials showed that the neutrophil-to-lymphocyte ratio, etiology and extra-hepatic spread are predictive factors of response to sorafenib, but did not identify any predictive biological markers. After 10 years of research into sorafenib there are still no validated prognostic or predictive factors of response to the drug in HCC. The aim of the present review was to summarize 10 years of research into sorafenib, looking in particular at the potential of associated clinical and biological markers to predict its efficacy in patients with advanced HCC. | Giorgia Marisi Alessandro Cucchetti Paola Ulivi Matteo Canale Giuseppe Cabibbo Leonardo Solaini Francesco G Foschi Serena De Matteis Giorgio Ercolani Martina Valgiusti Giovanni L Frassineti Mario Scartozzi Andrea Casadei Gardini | 2018 | World Journal of Gastroenterology2018，24，36： | 14 |
| 2 | Hydrocarbon degradation by a soil microbial population with β-cyclodextrin as surfactant to enhance bioavailability显示文摘 | Bardi L Mattei A Steffan S | 2000 | Enzyme and Microbial Technology2000，27，： | 2 |
| 3 | Mechanisms of ischemic preconditioning in skeletal muscle显示文摘 | Mattei A Chaloupka K | 2000 | J Surg Res2000，94，： | 1 |
| 4 | In vivo requirement forAtg5 in antigen presentation by dendritic cells显示文摘 | Lee H K Mattei L M Steinberg B E | 2010 | Immunity2010，32，2： | 1 |
| 5 | House Price Differen- tials and Dynamics Evidence from the Los Angeles and San Francisco Metropolitan Areas 显示文摘 | Gabriel A S Mattey P J Wascher W L | 1999 | Economic Review-Federal Reserve Bank of San Francisco1999，，1： | 1 |
| 6 | Paediatric adenoidectomy:endoscopic coblation technique compared to cold curettage显示文摘 | DI RIENZO BUSINCO L ANGELONE A M MATTEI A | 2012 | Acta Otorhinolaryngol Ital2012，32，： | 1 |
| 7 | Allostatie load is associated with chronic conditions in the Boston Puerto Rican health study显示文摘 | Mattei J Demissie S Falcon L | 2010 | Soe Sci Med2010，70，： | 1 |
| 8 | Estradiol acts via estrogen receptors alpha and beta on pathways important for synaptie plasticity in the mouse hippoeampal formation 显示文摘 | Speneer JL Tsuda MC Mattei L | 2012 | Neuroseienee2012，202，7： | 1 |
| 9 | Mobilization of CD34^+CD38^- hematopoietic stem cells after priming in acute myeloid leukemia显示文摘AIM: To evaluate quantitatively and qualitatively the different CD34+cell subsets after priming by chemotherapy granulocyte colony-stimulating factor(± G-CSF)in patients with acute myeloid leukemia.METHODS: Peripheral blood and bone marrow sampleswere harvested in 8 acute myeloid leukemia patients during and after induction chemotherapy. The CD34/CD38 cell profile was analyzed by multi-parameter flow cytometry. Adhesion profile was made using CXC chemokine receptor 4(CXCR4)(CD184), VLA-4(CD49d/CD29) and CD47.RESULTS: Chemotherapy ± G-CSF mobilized immature cells(CD34+CD38 population), while the more mature cells(CD34+CD38lowand CD34+CD38+populations) decreased progressively after treatment. Circulating CD34+cells tended to be more sensitive to chemotherapy after priming with G-CSF. CD34+cell mobilization was correlated with a gradual increase in CXCR4 and CD47expression, suggesting a role in cell protection and the capacity of homing back to the marrow.CONCLUSION: Chemotherapy ± G-CSF mobilizes into the circulation CD34+bone marrow cells, of which, the immature CD34+CD38-cell population. Further manipulations of these interactions may be a means with which to control the trafficking of leukemia stem cells to improve patients' outcomes. | Adriana Plesa Eve Mattei Charles Dumontet Youcef Chelghoum Hélène Labussière Giovanna Cannas Mauricette Michallet Xavier Thomas Mohamed Elhamri Stéphane Morisset Inès Tagoug | 2013 | World Journal of Stem Cells2013，5，4： | 1 |
| 10 | Impacts of ionizing radiation on volatile production by ripening gala apple fruit显示文摘 | FAN Xuetong ARGENTA L MATTEIS J P | 2001 | Journal of Agricultural & Food Chemistry2001，49，1： | 1 |
| 11 | Obesity and comorbidity are independently associated with a failure to achieve remission in patients with established rheumatoid arthritis显示文摘 | Ellerby N Mattey 0 L PackhamJ | 2014 | Ann Rheum Dis2014，73，11： | 1 |
| 12 | Glutamine-enriched parenteral nutrition after autologous peripheral blood stem cell transplantation: effects on immune reconstitution and mucositis显示文摘 | Piccirillo N De Matteis S Laurenti L | 2003 | Haematologica2003，88，2： | 1 |
| 13 | Polygalacturonase-lnhibiting Proteins (PGIPs) with different specificities are expressed in Phaseolus vulgaris 显示文摘 | Desiderio A Aracri B Leckie F Mattei B Salvi G Tigelaar H Van Roekel J S C Baulcombe D C Melchers L S De Lorenzo G Cervone F | 1997 | Molecular Plant-Microbe Interactions1997，10，7： | 1 |
| 14 | Seronegative spondylarthropathies:imaging of spondylitis,enthesitis and dactylitis显示文摘 | Barozzi L Olivier I De Matteis M | 1998 | Eur J Radiol1998，27，1： | 1 |
| 15 | Localization of the human c-kit protooncogene on the q 11 -q 12 region of chromosome 4 显示文摘 | Auriol L Mattei MG Andre C | 1998 | Hum Gen- et1998，78，4： | 1 |
| 16 | Rotation Capacity of Aluminum Beams under Moment Gradient II:Numerical Simulations显示文摘 | MOEN L A MATTEIS G D HOPPERSTAD O S | 1999 | Journal of Structural Engineering1999，125，8： | 1 |
| 17 | The speciWcity of polygalacturonaseinhibiting protein (PGIP) : a single amino acid substitution in the solvent-exposed β-strand/13-turn region of the leucine-rich repeats (LRRs) conferconfers a new recognition capability 显示文摘 | Leckie F Mattei B Capodicasa C Hemmings A Nuss L Aracri B DeLorenzo G Cervone F | | The EMBO J0，18，： | 1 |
| 18 | The crystal structure of PGIP (polygalacturonase-inhibiting protein), a leucine-rich repeat protein involved in plant defense 显示文摘 | Di Matteo A Federici L Mattei B Salvi G Johnson K A Savino C DeLorenzo G Tsernoglou D Cervone F | 2003 | Proc Natl Acad Sci2003，100，10： | 1 |
| 19 | Review of the pathophysiology and management of postoperative ileus显示文摘 | Mattei P Rombeau J L | 2006 | World Journal of Surgery2006，30，8： | 1 |
| 20 | Cross-sectional Classification for Aluminum Beams-Parametric Study显示文摘 | MATTEIS G D MOEN L A LANGSETH M | 2001 | Journal of Structural Engineering2001，127，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员