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| 1 | Performance of a bismuth bulk rotating disk electrode for heavy metal analysis : determination of lead in environmental samples 显示文摘 | Marla de la Gala Morales Rosario Palomo Marln Lorenzo Calvo Blaquez | 2012 | Electroanalysis2012，24，5： | 1 |
| 2 | Atherosclerosis,oxida- tive stress and physical activity显示文摘 | Calder6n JG Femdndez AZ Marla de | 2008 | Invest Clin2008，49，3： | 1 |
| 3 | Development of the American Association of Critical-Care Nurses' Sedation Assessment Scale for Critically Ill Patients显示文摘 | Maj Marla J De Jong Suzanne M Burns Margaret L Campbell | 2005 | Am J Crit Care2005，14，： | 1 |
| 4 | Insoluble and soluble dietary fi-ber values measured by enzymatic gravi-metric method in cereal grains显示文摘 | Leila Picollida Silva Marla de Lourdes San-torio Ciocca | 2005 | Food Composition and Analysis2005，，18： | 1 |
| 5 | Measurement of Anxiety for patients with cardiac disease显示文摘 | Marla J De Jong Lynne A Hall | 2006 | Journal of Cardiovascular Nursing2006，21，5： | 1 |
| 6 | Influence of different rare earth ions on hydrogen transfer over Y zeolite 显示文摘 | Gabriela de la Puente Eduardo Falvabella Souza-Aguiar Fatima Marla Zanon Zotin | 2000 | Applied Catalysis A General2000，197，： | 1 |
| 7 | Curcumin in inflammatory bowel diseases:Cellular targets and molecular mechanisms显示文摘Curcumin,a natural product,has exhibited promising effects in both animal models and clinical trials,interacting with a multitude of factors linked to Inflammatory Bowel Disease(IBD).These factors encompass cytokines,oxidative stress-associated enzymes,and modulation of the intestinal microbiota.Notably,curcumin has demonstrated therapeutic potential in animal models of colitis,wherein it exerts a negative regulatory influence on pivotal signaling pathways such as PI3/Akt,JAK/STAT,andβ-catenin.Moreover,it inhibits the expression of proinflammatory enzymes and co-stimulatory molecules(including RANKL,ICAM-1,CD205,CD256,TLR4,among others),while curbing immune cell chemotaxis,thereby attenuating the characteristic neutrophil infiltration observed in IBD.Another facet of curcumin’s action involves its modulation of the intestinal microbiota.Notably,the microbiota itself contributes to beneficial biotrans formations of curcumin,thereby enhancing its effectiveness in IBD treatment.On a clinical front,curcumin has demonstrated the ability to induce clinical and/or endoscopic remission without any reported toxic effects.Hence,curcumin warrants consideration as an adjunctive therapy in IBD management.Subsequent clinical investigations should concentrate on meticulously evaluating curcumin’s impact on these precise therapeutic targets. | AMYLLY SANUELLY DA PAZ MARTINS MARLA DE CERQUEIRA ALVES ORLANDO ROBERTO PIMENTEL DE ARAÚJO FABIANA OLIVEIRA DOS SANTOS CAMATARI MARÍLIA OLIVEIRA FONSECA GOULART FABIANA ANDRÉA MOURA | 2023 | BIOCELL2023，47，11： | 0 |
| 8 | Ionic liquid-loaded microcapsules doped into dental resin infiltrants显示文摘Resin infiltrants have been effectively applied in dentistry to manage non-cavitated carious lesions in proximal dental surfaces.However,the common formulations are composed of inert methacrylate monomers.In this study,we developed a novel resin infiltrant with microcapsules loaded with an ionic liquid(MC-IL),and analyzed the physical properties and cytotoxicity of the dental resin.First,the ionic liquid 1-n-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide(BMI.NTf2)was synthesized.BMI.NTf2 has previously shown antibacterial activity in a dental resin.Then,MC-IL were synthesized by the deposition of a preformed polymer.The MC-IL were analyzed for particle size and de-agglomeration effect via laser diffraction analysis and shape via scanning electron microscopy(SEM).The infiltrants were formulated,and the MC-IL were incorporated at 2.5%,5%,and 10 wt%.A group without MC-IL was used as a control.The infiltrants were evaluated for ultimate tensile strength(UTS),contact angle,surface free energy(SFE),and cytotoxicity.The MC-IL showed a mean particle size of 1.64(±0.08)μm,shriveled aspect,and a de-agglomeration profile suggestive of nanoparticles’presence in the synthesized powder.There were no differences in UTS among groups(p>0.05).The incorporation of 10 wt%of MC-IL increased the contact angle(p<0.05),while the addition from 5 wt%reduced the SFE in comparison to the control group(p<0.05).The human cell viability was above 90%for all groups(p>0.05).The incorporation of microcapsules as a drug-delivery system for ionic liquids may be a promising strategy to improve dental restorative materials. | Marla Cuppini Isadora Martini Garcia Virgínia Serra de Souza Kelly Cristine Zatta Fernanda Visioli Vicente Castelo Branco Leitune Sílvia Stanisçuazki Guterres Jackson Damiani Scholten Fabrício Mezzomo Collares | 2021 | Bioactive Materials2021，6，9： | 0 |
| 9 | Efficacy of oral consumption of curcumin/Curcuma longa for symptom improvement in inflammatory bowel disease:A systematic review of animal models and a meta-analysis of randomized clinical trials显示文摘The roots of the vegetal Curcuma due to its high content of polyphenols,has been used successfully in several clinical situations.This review assessed the effect of curcumin/Curcuma longa on symptoms and metabolic changes in inflammatory bowel disease(IBD).A systematic review of animal models and randomized clinical trials(RCTs)was conducted by searching the following electronic databases:PubMed,CENTRAL,LILACS,Science Direct,and ClinicalTrials.gov.From 997 found records,62 were included.More than 90%of the animal studies reported an improvement in macroscopic,histologic and/or functional activity;80%identified decreased oxidative and/or inflammatory biomarkers in animals treated with curcumin.Among the RCTs,intention-to-treat analysis showed that oral curcumin was effective in inducing clinical remission(n=281,RR:3.15 CI 95%[1.22–8.10]p=0.0017;i2=72.2%,p=0.006)and clinical response(n=259,RR:1.60 CI 95%[1.09–2.35]p=0.0017;i2=59.7%,p=0.042)but not endoscopic remission(n=161,RR:2.91 CI 95%[0.58–14.58]p=0.195;i2=72.7%,p=0.026).These results confirm that oral supplementation with curcumin/Curcuma longa has beneficial actions in animal colitis and,when associated with drug therapy,is effective in the treatment of patients with IBD. | MARLA DE CERQUEIRA ALVES MONISE OLIVEIRA SANTOS NASSIB BEZERRA BUENO ORLANDO ROBERTO PIMENTEL DE ARAúJO MARíLIA OLIVEIRA FONSECA GOULART FABIANA ANDRéA MOURA | 2022 | BIOCELL2022，46，9： | 0 |
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