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| 1 | Pain sensation in pancreatic diseases is not uniform: The different facets of pancreatic pain显示文摘AIM: To systematically characterize specific pain patterns in the most frequent pancreatic diseases.METHODS: Pain in patients with chronic pancreatitis(n = 314), pancreatic cancer(n = 469), and other pancreatic tumors(n = 249) including mucinous(n = 20) and serous cystadenoma(n = 31), invasive(n = 37) and non-invasive intraductal papillary mucinous neoplasia(IPMN; n = 48), low stage(n = 18) and high stage neuroendocrine neoplasia(n = 44), and ampullary cancer(n = 51) was registered and correlated with clinicopathological data. Survival times were estimated by the Kaplan-Meier method. Patients alive at the follow-up time were censored. Survival curves were compared statistically using the log-rank test.RESULTS: Forty-nine point one percent of pancreatic cancer patients revealed no pain, whereas in chronic pancreatitis only 18.3% were pain free. In contrary, moderate/severe pain was registered in 15.1% in pancreatic cancer patients that was increased in chronic pancreatitis with up to 34.2%. Serous cystadenoma was asymptomatic in most cases(58.1%), whereas 78.9% of all mucinous cystadenoma patients suffered pain. In neuroendocrine neoplasia pain was not a key clinical symptom since 64% of low stage neuroendocrine neoplasia and 59% of high stage neuroendocrine neoplasia patients were pain free. Cancer localization in the pancreatic body and patients with malignant pancreatic neoplasms were associated with more severe pain. Tumor grading and stage did not show any impact on pain. Only in pancreatic cancer, pain was directly associated with impaired survival.CONCLUSION: Pancreatic pain depicts different patterns of abdominal pain sensation according to the respective pancreatic disorder and does not allow a unification of the term pancreatic pain. | Jan G D'Haese Mark Hartel Ihsan Ekin Demir Ulf Hinz Frank Bergmann Markus W Büchler Helmut Friess Güralp O Ceyhan | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 2 | 不锈钢研发的最新进展——奥氏体、铁素体和双相不锈钢显示文摘评价了近期不锈钢的部分工业发展状况。对于奥氏体不锈钢而言,有两大引人注目的合金开发方向:低镍奥氏体不锈钢和高氮奥氏体不锈钢。这两类合金的设计目的不同,尤其是强度方面,但其合金开发原理和科研方法很相似,都围绕着氮这一合金元素对强度、塑性和耐蚀性的积极作用展开。现在人们已经相当了解氮对固溶强化、晶界强化和加工硬化的影响以及如何充分利用这些影响来开发全球市场所需的材料。在耐蚀性方面,铁素体、奥氏体和双相不锈钢彼此竞争,有关其耐蚀性比较的实验室数据也越来越多。但是,对于实际应用和合金选择而言,仅仅是实验室的数据是不够的,因此文章给出了多年来对24种工业生产的不锈钢暴露在室外海洋大气环境下的最新耐蚀性研究结果。希望在不久的将来能将更多制造商提供的钢种纳入到此项耐蚀性研究中来。这既能帮助消费者合理地选择合金,也可以帮助钢铁生产企业开发合适的钢种。 | Markus O Speidel Markus Diener | 2011 | 世界钢铁2011，11，1： | 3 |
| 3 | Hydraulic functions for sw- elling soils: pore scale considerations显示文摘 | MARKUS T DANI O | 2003 | Journal of Hydrology2003，272，1： | 1 |
| 4 | Brief cognitive assessment for patients with cerebral small vessel disease 显示文摘 | O'Sullivan M Morris RG Markus HS | 2005 | J Neurol Neurosurg Psychiatry2005，76，8： | 1 |
| 5 | Pylorus preservation has no impact on delayed gastric emptying 'after pancreatic head resection 显示文摘 | Horstmann O Markus PM Ghadimi MB | 2004 | Pancreas2004，28，1： | 1 |
| 6 | Brief cognitive assessment for patients with cerebral small vessel disease显示文摘 | O'Sullivan M Morris RG Markus HS | 2005 | J Neurol Neurosurg Psychiatry2005，76，8： | 1 |
| 7 | Brief cognitive assessment for patients with cerebral small vessel disease显示文摘 | O'Sullivan M Morris RG Markus HS | 2005 | Neurol Neurosurg Psychiatry2005，76，8： | 1 |
| 8 | Lotus-effects-surfaces显示文摘 | Edwin N Markus O | 2002 | Macromol Symp2002，187，： | 1 |
| 9 | Nanograin size, high-nitrogen austenitic stainless steels 显示文摘 | Speidel Markus O | 2003 | Z Metallkd2003，94，： | 1 |
| 10 | Brief cognitive assessment for patients with cerebral small vessel disease 显示文摘 | O'Sullivan M Morris RG Markus HS | 2005 | J Neurol Neurosurg Psychiatry2005，76，8： | 1 |
| 11 | Brief cognitive assessment for patients with cerebral small vessel disease显示文摘 | O' Sullivan M Mnorris RG Markus HS | | 0，，08： | 1 |
| 12 | Brief cognitive assessment for patients with cerebral small vessel disease 显示文摘 | O'sullivan M Morris RG Markus HS | 2005 | J Neurel Neuro- surg Psychiatry2005，76，： | 1 |
| 13 | Modelling the dynamics of fish contamination by Chernobyl radioncaesium: an analytical solution based on potassium mass balance显示文摘 | Alexei O Koulikov Markus Meili | 2003 | Journal of Environmental Radionactivity2003，66，： | 1 |
| 14 | MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL显示文摘 | M. O’Sullivan J.M. Jarosz R.J. Martin N. Deasy J.F. Powell H.S. Markus | 2001 | Neurology2001，，5： | 1 |
| 15 | Nickel and chromium- based high nitrogen alloys 显示文摘 | Speidel Hannes J C Speidel Markus O | 2004 | Materials and Manufacturing Processes2004，19，： | 1 |
| 16 | Three - dimensional measurement of femoral antetorsion: comparison to a conventional radiological method 显示文摘 | Musa C Markus O Padhraig F | 2010 | Arch Orthop Trauma Surg2010，130，： | 1 |
| 17 | Brief cognitive assessment for patients with cerebral small vessel disease 显示文摘 | O' Sullivan M Morris RG Markus HS | 2005 | J Neurol Neurosurg Psychiatry2005，76，8： | 1 |
| 18 | Cisternal S100 protein and neuron-specific enolase are elevated and site-specific markers in intractable temporal lobe epilepsy显示文摘 | Steinhoff BJ Tumani H Markus O | 1999 | Epilepsy Research1999，36，1： | 1 |
| 19 | Frequency stabi- lization of a Q-switched Nd : YAG laser oscillator with sta- bility better 300 kHz following an rf-sideband scheme显示文摘 | MARTIN O THOMAS W MARKUS G | 2009 | Optics Communications2009，282，16： | 1 |
| 20 | Rapid and simple micromethod for the simultaneous determination of 3-MCPD and 3- MCPD esters in different foodstuffs显示文摘 | MARKUS K S UTE B ALEXANDRA O G | 2010 | J Agric Food Chem2010，58，11： | 1 |
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