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| 1 | 单细胞基因组学分析的技术前沿显示文摘基因组学已经深刻地改变了生命科学的诸多领域的面貌。目前它的主要内容是新的全基因组碱基序列的测定和在全基因组范围内鉴定那些在不同水平上影响生命活动的基因群的功能和相互作用。为达此要求,近年出现的第二代测序(深度测序)技术和基因芯片技术发挥了关键作用,但是两者都需要足够的高质量的核酸样品。所以,在只有或只能用单细胞或极少量细胞的情况下,如果没有特殊手段,上述分析往往不能常规、方便地进行。文章以DNA扩增为主线,综合阐述了目前在单细胞(特别是微生物)全基因组测序和大基因组的靶向重测序,以及对单细胞或微量细胞进行的基于深度测序或芯片杂交的功能基因组分析,如转录组、ChIP和DNA的CpG甲基化分析等的最新策略和技术,评价了单细胞基因组测序和功能基因组学各技术的特点并对发展前景进行了展望。 | 潘星华 朱海英 MARJANI Sadie L. | 2011 | 遗传2011，33，1： | 5 |
| 2 | Inoperable esophageal cancer and outcome of palliative care显示文摘AIM:To determine the outcome of esophageal cancer patients referred for palliative care,in Gorgan and Gonbad gastrointestinal clinics,northeast of Iran. METHODS:This cross-sectional study was done on inoperable esophageal cancer cases referred to gastrointestinal clinics in Gorgan and Gonbad city(2005-2006) . Demographic data were collected during the procedure and cases were followed up every one month. Improvement proportion was calculated with 95% confidence interval,to determine the rate of improvement. Survival analysis and Kaplan-Meier methods were used to estimate the duration of palliative care effectiveness. RESULTS:We recruited 39 cases into the study. Squamous cell carcinoma was the most prevalent(92.3%) . The middle third of the esophagus was involved predominantly(51.3%) . Dilation was the most preferred method(89.7%) and stenting was done in 4 cases. Decreasing dysphagia score was not related to palliation method or pathology type of carcinoma. Age of the patients was significantly related to the improvement of dysphagia score. Mean survival time was 137.6 d and median was 103 d. CONCLUSION:Results of this study showed a low survival rate after palliative care in esophageal cancer cases despite dysphagia scores' improvement after dilating or stenting. | Sima Besharat Ali Jabbari Shahryar Semnani Abbasali Keshtkar Jeran Marjani | 2008 | World Journal of Gastroenterology2008，14，23： | 5 |
| 3 | Silica triflate as an efficient reagent for the solvent-free synthesis of coumarins显示文摘作为新基于硅石的试剂,硅石 triflate 能在没有溶剂的反应条件下面经由 Pechmann 反应被用于 4 代用品香豆素的有效合成。所有反应在 80 ° C 被执行在对高产率好。 | Farhad Shirini Katayoun Marjani Hossein Taherpour Nahzomi Mohammad Ali Zolfigol | 2007 | Chinese Chemical Letters2007，18，8： | 1 |
| 4 | Diabetes mellitus and tuberculosis facts and controversies 显示文摘 | Baghaei P Marjani M Javanmard P | 2013 | J Diabetes Metab Disord2013，12，1： | 1 |
| 5 | First-line anti-tuberculosis drug resistance patterns and trends at the national TB referral center in Dan-eight years of surveillance 显示文摘 | Shamaei M Marjani M Chitsaz E | 2009 | Int J Infect Dis2009，13，5： | 1 |
| 6 | Diagnostic yield of post-bronchoscopy sputum smear in pulmonary tuberculosis 显示文摘 | Malekmohammad M Marjani M Tabarsi P | 2012 | Scand J Infect Dis2012，44，： | 1 |
| 7 | Factors associatedwith death or intensive care unit admission due to pandemic2009 influenza A (H1N1) infection 显示文摘 | Tabarsi P Moradi A Marjani M | 2011 | Ann Thorac Med2011，6，2： | 1 |
| 8 | First-line anti-tu- berculosis drug resistance patterns and trends at the Na- tional TB referral center in Iran-eight years of sur- veillance显示文摘 | Shamaei M Marjani M5Chitsaz E | 2009 | Int J Infect Dis2009，13，5： | 1 |
| 9 | Factors associated with death or intensive care unit admission due to pandemic 2009 influenza A ( H1 N1 ) infection 显示文摘 | TABARSI P MORADI A MARJANI M | 2011 | Ann Thorac Med2011，6，2： | 1 |
| 10 | Spontaneous Iliac vein rupture: case report and comprehensive review of the literature显示文摘 | Tannous H Nasrallah F Marjani M | 2006 | Ann Vasc Surg2006，20，2： | 1 |
| 11 | Mortgage Loan Portfolio Optimization Using Muhi-stage Stochastic Programming显示文摘 | Kourosh Marjani Rasmussen Jens Clausen | 2007 | Journal of Economic Dynamics & Control2007，31，： | 1 |
| 12 | Factors associated with death or intensive care unit admission due to pandemic 2009 influenza A(H1N1) infection显示文摘 | Tabarsi P Moradi A Marjani M | 2011 | Ann Thorac Med2011，6，2： | 1 |
| 13 | Diagnostie yield of post-bronchoscopy sputum smear in pulmonary tuberculosis显示文摘 | Malekmohammad M Marjani M Tabarsi P | 2012 | Seand J Infect Dis2012，44，5： | 1 |
| 14 | Microwave-assisted aldol condensation of benzil with ketones显示文摘在微波照耀下面,相应 hydroxycyclopentenones 被 benzil 的跨丁间醇醛的反应与各种各样的酉同类在高收益准备。当反应在很长时间的古典加热下面在各种各样的溶剂被执行时,他们在相对低的收益生产了产品。 | Katayoun Marjani Maryam Asgari Akram Ashouri Gholam Hossein Mahdavinia Hossien Abbastabar Ahangar | 2009 | Chinese Chemical Letters2009，20，4： | 1 |
| 15 | Pulmonary aspergillosis in solid organ transplant patients: A report from Ir显示文摘 | MARJANI M TABARSI P NAJAFIZADEH K | 2008 | Transplant Proc2008，40，10： | 1 |
| 16 | Behavior of brick infilled reinforced concrete frames under reversed cyclic loading显示文摘 | MARJANI F ERSOY U | | 0，，2： | 1 |
| 17 | A comparison of bone reconstruction following application of bone matrix gelatin and autogenous bone grafts to alveolar defects:an animal study显示文摘 | Bayat M Momen-Heravi F Marjani M | | 0，，04： | 1 |
| 18 | Prognostic factors for esophageal squamous cell carcinoma:a-population-based study in Golestan province Iran,a high incidence area显示文摘 | Aghcheli K Marjani HA Nasrollahzadeh D | 2011 | PLOS ONE2011，6，： | 1 |
| 19 | A comparison of bone reconstruction following application of bone matrix gelatin and autogenous bone grafts to alveolar defects: an animal study 显示文摘 | Bayat M Momen-H~ravi F Marjani M | 2010 | J CranioMaxilloFac Surg2010，38，4： | 1 |
| 20 | Active pulmonary tuberculosis manifesting with idiopathic thrombocytopenic purpura: a rare presentation显示文摘 | Payam Tabarsi Muayad Aghali Merza Majid Marjani | 2010 | Brazilian Journal of Infectious Diseases2010，，6： | 1 |
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