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30篇 您的检索式：作者名="Marinelli RA"

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	题名	作者	年代	出处	被引量
1	Aquaporins:Their role in cholestatic liver disease显示文摘This review focuses on current knowledge on hepato-cyte aquaporins(AQPs)and their significance in bile formation and cholestasis.Canalicular bile secretion results from a combined interaction of several solute transporters and AQP water channels that facilitate water flow in response to the osmotic gradients created. During choleresis,hepatocytes rapidly increase their canalicular membrane water permeability by modulating the abundance of AQP8.The question was raised as to whether the opposite process,i.e.a decreased canalicular AQP8 expression would contribute to the development of cholestasis.Studies in several experimental models of cholestasis,such as extrahepatic obstructive cholestasis,estrogen-induced cholestasis, and sepsis-induced cholestasis demonstrated that the protein expression of hepatocyte AQP8 was impaired. In addition,biophysical studies in canalicular plasma membranes revealed decreased water permeability associated with AQP8 protein downregulation.The combined alteration in hepatocyte solute transporters and AQP8 would hamper the efficient coupling of osmotic gradients and canalicular water flow.Thus cholestasis may result from a mutual occurrence of impaired solute transport and decreased water permeability.	Guillermo L Lehmann Maria C Larocca Leandro R Soria Raúl A Marinelli	2008	World Journal of Gastroenterology2008，14，46：	8
2	Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes显示文摘	Marinelli RA Tietz PS Pham LD	1999	Am J Physiol1999，276，：	1
3	Water transport by epithelia of the digestive tract显示文摘	Masyuk AI Marinelli RA LaRusso NF	2002	Gastroenterology2002，122，2：	1
4	Expression of aquaporin-4 water channels in rat cholangiocytes显示文摘	Marinelli RA Pham LD Tietz PS	2000	Hepatology2000，31，6：	1
5	Aquaporin water channels in central nervous system显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，4：	1
6	Aquaporin water channels in central nervous system显示文摘	Lehmann GL Gradilone SA Marinelli RA		0，，04：	1
7	Aquaporin water channels in central nervous system显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，4：	1
8	AQP4 transfected into mouse cholangiocytes promotes water transport in biliary epithelia 显示文摘	Splinter PL Masyuk AI Marinelli RA	2004	Hepatology2004，39，：	1
9	Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes显示文摘	Marinelli RA Tietz PS Pham LD	1999	Am J Physiol Gastrointest Liver Physiol1999，276，11：	1
10	Aquaporin water channels in central nervous system显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，：	1
11	Water transporting properties ofhepatocyte basolateral and canalicular plasma membrane domains显示文摘	Marinelli RA Tietz PS Caride AJ	2003	Biol Chem2003，278，43：	1
12	Aquaporin water channels in central nervous system显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，4：	1
13	查看详情显示文摘	Marinelli RA		0，，：	1
14	Water transporting properties- of hepatocyte basolateral and canalicular plasma membrane domains 显示文摘	Marinelli RA Tietz PS Caride M	2003	Biol Chem2003，278，43：	1
15	Mitochondrial aquaporin-8 knockdown in human hepatoma HepG2 cells causes ROS-induced mitochondrial depolarization and loss of viability显示文摘	Maria Julia Marchissio Daniel Eleazar Antonio Francés Cristina Ester Carnovale Raúl Alberto Marinelli	2012	Toxicology and Applied Pharmacology2012，，2：	1
16	Aquaporin water channels in central nervous system 显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，：	1
17	Hepatoeyte aquaporins in bile formation and cholestasis显示文摘	Marinelli RA Lehmann GL Soria LR	2011	Front Biosci (Landmark Ed)2011，16，：	1
18	Aquaporin water channels in central nervous system 显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，4：	1
19	Water transport by epithelia of the digestive tract 显示文摘	Masyuk AI Marinelli RA LaRusso NF	2002	Gastroenterology2002，122，：	1
20	Aquapofin water channels in central nervous system 显示文摘	Lehmann GL Gradilone SA Marinelli RA	2004	Curr Neurovasc Res2004，1，4：	1

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