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| 1 | Obstructive jaundice in Iran:factors affecting early outcome显示文摘BACKGROUND:Understanding any factors which influence the morbidity and mortality in patients with obstructive jaundice in each society will better guide appropriate management and lead to improved survival This study aimed to assess baseline etiologies,clinical manifestations,diagnostic results,and morbidity and mortality related to obstructive jaundice in Iranian patients. METHODS:The hospital recorded files of 133 patients with the final diagnosis of obstructive jaundice who had been admitted to the Taleqhani Hospital in Tehran between January 2001 and September 2004 were reviewed. RESULTS:The most common etiologies of obstructive jaundices were neoplasia and then common bile duct stone in the two genders.The results of ultrasonography were positive in less than half of the patients.However,the most positive results were related to endoscopic retrograde cholangiopancreatography(ERCP).The in-hospital mortality rate in patients less than 50 years old and elderly patients was 0%and 6.76%,respectively.The in-hospital morbidity rate was 2.25%and 7.51%,respectively in both patients and it was commonly related to infection of ulcer (44.46%),pneumonia(14.75%),myocardial infarction (14.75%),and subdiaphragmatic abscess(11.29%).In patients with a diagnosis of benign obstruction,only one patient died of severe sepsis.In malignant group preoperative characteristics,such as weight loss(P=0.015) and serum bilirubin concentration more than 16 mg/dl and postoperative complications,such as sepsis(P<0.001) cardiac arrest(P<0.001),and hepatic coma(P<0.001)were main predictors for the in-hospital mortality rate.CONCLUSION:Although the mortality and morbidity of obstructive jaundice in our study are less than those in other studies,the determination of preoperative clinical and laboratory indices and postoperative complications of patients is needed for the control of mortality and morbidity rate. | Mehrdad Moghimi Seyed Ali Marashi Mohammad Taghi Salehian Mehrdad Sheikhvatan | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，5： | 9 |
| 2 | Discernment scheme for paraquat poisoning: A five-year experience in Shiraz, Iran显示文摘AIM To evaluate various schemes for paraquat poisoning and different variables that influence the outcome of acute paraquat poisoning.METHODS In a cross-sectional study, the information about all cases of acute paraquat poisoning who were admitted to teaching hospitals affiliated to Shiraz University of Medical Sciences, in a five year period(September 2010 to September 2015) were evaluated. The variables included: Demographic data, medical assessment, therapeutic options, laboratory findings, and the outcomes. Data were analyzed using SPSS, version 22. Significant difference between groups was tested using t-test for continues outcomes and χ~2 test for categorical. The significance level was considered to be P < 0.05. RESULTS A total of 104 patients(66.3% male) were evaluated. The mean age of the female patients was 22.81 ± 9.87 years and the male patients' was 27.21 ± 11.06 years. Ninety seven(93.3%) of all the cases were suicide attempts with mortality rate of 43.2%. Despite the necessity for emergency hemodialysis during the first 6 h of intoxication, none of the patients had dialysis during this time. Immunosuppressive and corticosteroid medications were not administrated in adequate dosage in 31.1% and 60% of the patients, respectively. Ingestion of more than22.5 cc of paraquat and increase in creatinine level were the most important predictors of mortality.CONCLUSION Treatment should start immediately for these patients.Moreover, creating a clinical guideline according to the findings can have an impact on the treatment procedure which seems to be necessary. | Saeed Kavousi-Gharbi Reza Jalli Akbar Rasekhi-Kazerouni Zahra Habibagahi Sayed Mahdi Marashi | 2017 | World Journal of Experimental Medicine2017，7，1： | 8 |
| 3 | Design of a multiplex PCR method for detection of toxigenicpathogenic in Vibrio cholerae显示文摘Objective:To study virulence and regulatory genes(hlyA,ctxB,tcpI) in clinical strains of Vibrio ckolerae(V.cholerae),simultaneously.Methods:Three important genes,tepI,hlyA and ctxB were used for detection of toxigenic and pathogenic V.cholera by chain reaction assay method. Results:According to the results of the PCR,the incidence of hlyA,tcpI,and ctxB genes in clinical isolates was obtained as 94.7%(72 sample),90.8%(69 sample),and 92.1%(70 sample), respectively.Five strains possessed all genes except ctxB,six strains possessed all genes except tcpI,four strains possessed all genes except hlyA,one strain possessed only hlyA and 60 strains contained a combination of three genes.Including hlyA,ctxB and tcpI,Conclusions:Result show that this method could be reliable to detect toxigenic-pathogenic strains of V.cholerae in Iran. | Abbas Ali Imani Fooladi Iman Islamieh D Hosseini Doust R Karami A Marashi SM | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，2： | 2 |
| 4 | Attenuation of hemodynamic responses following laryngoscopy and tracheal intubation-comparative assessment of clonidine and gabapentin premedication显示文摘 | Marashi SM Ghafari MH Saliminia A | 2009 | Middle East J Anesthesiol2009，20，2： | 1 |
| 5 | Analysis and impact ofdelays in ambulance to emergency department handovers 显示文摘 | Cone DC Middleton PM Marashi Pour S | 2012 | Emerg Med Australas2012，24，5： | 1 |
| 6 | Effect of pre-emptive gabapen-tin on postoperative pain following lower extremity orthopaedic surgery un-der spinal anaesthesia显示文摘 | Panah KM Yaghooti AA Marashi SH | 2011 | Singapore Med J2011，52，12： | 1 |
| 7 | Why major nonenzymatic glycation sites of human serum albumin are preferred to other residues? 显示文摘 | Marashi SA Safarian S Moosavi-Movahedi AA | 2005 | Med Hypotheses2005，64，4： | 1 |
| 8 | Exploration emotionality and hippocampalm ossy fibers in nonaggressive AB/Gat and congenic highly aggressive mice显示文摘 | Prior H Schwegler H Marashi V | 2004 | Hippocampus2004，14，： | 1 |
| 9 | Trans- parent conductive thin film of ultra large reduced grapheme oxide monolayer 显示文摘 | NEKAHI A MARASHI P H HAGHSHENAS D | 2014 | Applied Surface Science2014，295，4： | 1 |
| 10 | Novel heart valve prosthesis with self-endothelialization potential made of modified polyhedral oligomericsilsesquioxane-nanocomposite material显示文摘 | Ghanbari H Radenkovic D Marashi SM | 2016 | Biointerphases2016，11，02： | 1 |
| 11 | Microstruc-ture and failure behavior of dissimilar resistance spot welds between low carbon galvanized and austenitic stainless steels 显示文摘 | Marashi P Pouranvari M Amirabdollahian S | 2008 | Materials Science and Engineering:A2008，480，1： | 1 |
| 12 | MFM of nanocrystalline NdFeB: a study of the effect of processing route on the micromagnetic structure显示文摘 | AL-Khafaji M A Marashi S P H Rainforth W M | 1998 | Journal of Magnetism and Magnetic Materials1998，190，： | 1 |
| 13 | The effect of inter- critical heat treatment temperature on the tensile properties and work hardening behavior of ferrite - martensite dual phase steel sheets 显示文摘 | Movahed P Kolahgar S Marashi S | 2009 | Materials Science and Engineering A2009，，6： | 1 |
| 14 | Indirect role of microRNAs and transcription factors in the regulation of important cancer genes : A network biology approach 显示文摘 | Ahmadi M Jafari R Marashi SA | 2015 | Cell Mol Biol2015，61，6： | 1 |
| 15 | Effects of different forms of environmental enrichment on behavioral,endocrinological,and immunological parameters in male mice显示文摘 | Marashi V Barnekow A Ossendorf E | 2003 | Horm Behav2003，43，： | 1 |
| 16 | Attenuation of hemodynamie re- sponses following laryngoscopy and tracheal intubation-comparative as- sessment of clonidine and gabapantin premedication显示文摘 | Marashi SM Ghafafi MH Saliminia A | 2009 | Middle East J Anesthesio12009，20，2： | 1 |
| 17 | Attenuation of hemodynamic responses following laryngoscopy and tracheal intubation-comparative assessment of clonidine and gabapentin premedication显示文摘 | Marashi SM Ghafari MH Saliminia A | | 0，，02： | 1 |
| 18 | The Effect of Intercritical Heat Treatment Tempera- ture on the Tensile Properties and Work Hardening Behavior of Ferrite-martensite Dual Phase Steel Sheets 显示文摘 | MOVAHED P KOLAHGAR S MARASHI S P H | 2009 | Materials Science and Engineering A2009，518，12： | 1 |
| 19 | Attenuation of hemodynamic responses following laryngoscopy and tracheal intubation:comparative assessment of clonidine and gabapentin premedication显示文摘 | Marashi SM Ghafari MH Saliminia A | | 0，，02： | 1 |
| 20 | Exploration, emotionality, and hippocampal mossy fibers in nonaggressive AB/Gat and congenic highly aggressive mice 显示文摘 | Prior H Schwegler H Marashi V | 2004 | Hippocampus2004，14，： | 1 |
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