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| 1 | Six Minute Walk Test to assess functional capacity in chronic liver disease patients显示文摘AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six Minute Walk Distance (6MWD) was measured. RESULTS: The subjects were categorized into four groups. Group A (n = 45) healthy subjects (control); group B (n = 49) chronic hepatitis B patients; group C (n = 54) chronic hepatitis C patients; group D (n = 98) liver cirrhosis patients. The four groups differed in terms of 6MWDs (P < 0.001). The longest distance walked was 421 ± 47 m by group A, then group B (390 ± 53 m), group C (357 ± 72 m) and group D (306 ± 111 m). The 6MWD correlated with age (r = -0.482, P < 0.01), hemoglobin (r = +0.373, P < 0.001) and albumin (r = +0.311, P < 0.001) levels. The Child-Pugh classification was negatively correlated with the 6MWD in cirrhosis (group D) patients (r = -0.328, P < 0.01). At the end of a 12 mo follow-up period, 15 of the 98 cirrhosis patients had died from disease complications. The 6MWD for the surviving cirrhotic patients was longer than for non-survivors (317 ± 101 vs 245 ± 145 m, P = 0.021; 95% CI 11-132). The 6MWD was found to be an independent predictor of survival (P = 0.024). CONCLUSION: 6MWT is a useful tool for assessing physical function in CLD patients. We suggest that 6MWD may serve as a prognostic indicator in patients with liver cirrhosis. | Hatem F Alameri Faisal M Sanai Manal Al Dukhayil Nahla A Azzam Khalid A Al-Swat Ahmad S Hersi Ayman A Abdo | 2007 | World Journal of Gastroenterology2007，13，29： | 5 |
| 2 | Effectiveness of hepatitis B virus vaccination program in Egypt:Multicenter national project显示文摘AIM:To assess the effectiveness of hepatitis B virus(HBV) vaccination program among fully vaccinated children.METHODS:A national community based crosssectional study was carried out in 6 governorates representing Egypt. A total of 3600 children aged from 9 mo to 16 years who were fully vaccinated with HBV vaccine during infancy were recruited. Face to face interviews were carried out and sera were evaluated for hepatitis B surface antigen(HBsA g),anti-HBV core antibodies(total) and quantitative detection of hepatitis B surface antibody using enzyme linked immunoassays techniques. Samples positive to HBs Ag/anti-HBV core antibodies were subjected to quantitative HBV-DNA detection by real time polymerase chain reaction with 3.8 IU/L detection limit. RESULTS:Sero-protection was detected among 2059 children(57.2%) with geometric mean titers 75.4 ± 3.6 IU/L compared to 3.1 ± 2.1 IU/L among nonseroprotected children. Multivariate logistic analysis revealed that older age and female gender were the significant predicting variables for having non seroprotective level,with adjusted odds ratio 3.3,9.1and 14.2 among children aged 5 to < 10,10 to < 15 and ≥ 15 years respectively compared to those < 5 years and 1.1 among girls compared to boys with P < 0.01. HBs Ag was positive in 0.11% and breakthrough infection was 0.36% and 0.39% depending on positivity of anti-HBc and DNA detection respectively. The prevalence of HBV infection was significantly higher among children aged ≥ 7 years(0.59%) compared to 0.07% among younger children with odds ratio equal to 8.4(95%CI:1.1-64.2) and P < 0.01.The prevalence was higher among girls(0.48%) than boys(0.29%) with P > 0.05. C ON C LU S I ON :T he E gy pt ian c ompuls or y H B V vaccination program provides adequate protection. Occult HBV infection exists among apparently healthy vaccinated children. Adherence to infection control measures is mandatory. | Iman I Salama Samia M Sami Zeinab Nabil Ahmed Said Manal H El-Sayed Lobna A El Etreby Thanaa M Rabah Dalia M Elmosalami Amany T Abdel Hamid Somaia I Salama Aida M Abdel Mohsen Hanaa M Emam Safaa M Elserougy Amal I Hassanain Naglaa F Abd Alhalim Fatma A Shaaban Samia A Hemeda Nihad A Ibrahim Ammal M Metwally | 2015 | World Journal of Hepatology2015，7，22： | 2 |
| 3 | Software Project Management Approaches for Global Software Development: A Systematic Mapping Study显示文摘Global Software Development(GSD) is a well established field of software engineering with the benefits of a global environment. Software Project Management(SPM) plays a key role in the success of GSD. As a result, the need has arisen to study and evaluate the downsides of SPM for GSD, to thereby pave the way for the development of new methods, techniques, and tools with which to tackle them. This paper aims to identify and classify research on SPM approaches for GSD that are available in the literature, to identify their current weaknesses and strengths, and to analyze their applications in industry. We performed a Systematic Mapping Study(SMS) based on six classification criteria. Eighty-four papers were selected and analyzed. The results indicate that interest in SPM for GSD has been increasing since 2006. As a class of approaches, the most frequently reported methods(40%) are those used for coordination, planning, and monitoring, along with estimation techniques that can be used to better match a distributed project. SPM for GSD requires further investigation by researchers and practitioners, particularly with respect to cost and time estimations. These findings will help overcome the challenges that must to be considered in future SPM research for GSD, especially regarding collaboration and time-zone differences. | Manal El Bajta Ali Idri Joaquín Nicolás Ros José Luis Fernández-Alemán Juan Manuel Carrillo de Gea Félix García Ambrosio Toval | 2018 | Tsinghua Science and Technology2018，23，6： | 2 |
| 4 | Radiation synthesis of poly bydrogels and its application as a carrier for anticancer delivery显示文摘 | Nabila A Mazied Sahar A Ismail Manal F | 2009 | Radiation Physics and Chemistry2009，78，11： | 1 |
| 5 | New classes of PDE7 inhibitors identified by a fission yeast-based HTS显示文摘 | Manal A Alaamery Arlene R Wyman F Douglas Ivey | 2010 | Journal of Biomolecular Screening2010，15，4： | 1 |
| 6 | Radiation Synthesis of Polyampholytic and Reversible pH responsive Hydrogel and Its Application as Drug Delivery System显示文摘 | Abou Taleb Manal F | 2008 | Polymer Bulletin2008，61，3： | 1 |
| 7 | Humic acid foliar appli-cation to minimize soil applied fertilization of surface-irrigatedwheat显示文摘 | Shaaban S A Manal F M Afifi M M | 2009 | World Journal of Agricultural Sciences2009，5，2： | 1 |
| 8 | Improvement of alkaline protease production by Penicillium chrysogenum NRRL 792 through physical and chemical mutation, optimization, characterization and genetic variation between mutant and wild-type strains 显示文摘 | Ahmed F Afifi Heba I Abo-Elmagd Manal M Housseiny | 2014 | Annals of Microbiology2014，64，： | 1 |
| 9 | Role of S-adenosylmethionine, folate, and betaine in the treat ment of alcoholic liver disease: summary of a symposium显示文摘 | Vishnudutt Purohit Manal F Abdelmalek Shirish Barve | 2007 | Am J Clin Nutr2007，86，1： | 1 |
| 10 | Isolation and mutation trend analysis of influenza a virus subtype H9N2 in Egypt显示文摘 | Ahmed S Manal A Magdy F | 2012 | Virol2012，9，： | 1 |
| 11 | Phytoremediation: An ecological solution to heavy-metal-polluted soil and evaluation of plant removal ability显示文摘 | Nadia B Manal F Al-Qahtani K M | 2012 | World Applied Sciences Journal2012，16，9： | 1 |
| 12 | Using adaptive management to meet conservation goals 显示文摘 | FRANKLIN T M F HELINSKI R H MANALE A M | 2007 | Fish and Wildlife Response to Farm Bill Conservation Practices2007，7，1： | 1 |
| 13 | Feed restriction of pregnantnulliparous rabbit does: consequences on reproductive performanceand maternal behaviour 显示文摘 | Manal A F Tony M A Ezzo O H | 2010 | Anim Reprod Sci2010，120，14： | 1 |
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