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| 1 | Single center experience of capsule endoscopy in patients with obscure gastrointestinal bleeding显示文摘AIM:To identify optimum timing to maximize diagnostic yield by capsule endoscopy (CE) in patients with obscure gastrointestinal bleeding (OGIB).METHODS:We identified patients who underwent CE at our institution from August 2003 to December 2009.Patient medical records were reviewed to determine type of OGIB (occult,overt),CE results and complications,and timing of CE with respect to onset of bleeding.RESULTS:Out of 385 patients investigated for OGIB,284 (74%) had some lesion detected by CE.In 222 patients (58%),definite lesions were detected that could unequivocally explain OGIB.Small bowel ulcer/erosions secondary to Crohn's disease,tuberculosis or non-steroidal anti-inflammatory agent use were the commonest lesions detected.Patients with overt GI bleeding for < 48 h before CE had the highest diagnostic yield (87%).This was significantly greater (P < 0.05) compared to that in patients with overt bleeding prior to 48 h (68%),as well as those with occult OGIB (59%).CONCLUSION:We established the importance of early CE in management of OGIB.CE within 48 h of overt bleeding has the greatest potential for lesion detection. | Mahesh Kumar Goenka Shounak Majumder Sanjeev Kumar Pradeepta Kumar Sethy Usha Goenka | 2011 | World Journal of Gastroenterology2011，17，6： | 39 |
| 2 | Gilbert's syndrome: High frequency of the (TA)_7 TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene显示文摘瞄准:在吉伯的症候群(GS ) 在 UDP-glucuronosyltransferase 1 (UGT1A1 ) 基因识别变体并且在印度在正常控制之中在 TA 插入和它的影响的印度,以及频率为 TA 插入和 GS 估计在纯合性之间的协会。方法:95 个 GS 盒子和 95 正常控制被选择。肝工作,另外的测试被做。倡导者和 UGT1A1 基因的所有 5 前 ons 被重新定序。对新奇 trinucleotide 插入的功能的评价被做由在 silico 分析并且由估计 UGT1A1,倡导者活动在 Hep G2 由适当构造的酶记者试金执行了房间线。结果:在 GS 病人之中, 80% 为 TA 插入是同型结合的,它比从另外的种族组的报告高好几倍。吝啬的 UCB 水平与仅仅这插入的一个拷贝在个人之中被提高,它不与有二个拷贝的那些显著地不同。在 UGT1A1 基因的许多新 DNA 变体被发现,包括在倡导者的插入在 GS 病人的一个子集(10%) 发现了的 trinucleotide (猫) ,然而并非在正常之中控制。In-silico 分析证明在倡导者和功能的分析的合拢 DNA 的显著变化在 UGT1A1 基因源于这插入的抄写效率显示出 20 褶层减小,显著地从而提高 UCB 水平。结论:GS 的基因传染病学越过种族组是可变的,在 UGT1A1 倡导者变体之中的上位相互作用调制胆红素 glucuronidation。 | Shabana Farheen Sanghamitra Sengupta Amal Santra Suparna Pal Gopal Krishna Dhali Meenakshi Chakravorty Partha P Majumder Abhijit Chowdhury | 2006 | World Journal of Gastroenterology2006，12，14： | 29 |
| 3 | Capsule endoscopy:Present status and future expectation显示文摘Video capsule endoscopy(CE)since its introduction 13years back,has revolutionized our approach to small intestinal diseases.Obscure gastrointestinal bleed(OGIB)continues to be the most important indication for CE with a high sensitivity,specificity as well as positive and negative predictive values.It is best performed during ongoing bleed or immediately thereafter.Overt OGIB has a higher diagnostic yield than occult OGIB.However,even in iron deficiency anemia,CE is emerging as important investigation after initial negative work up.In suspected Crohn’s disease(CD),CE has been shown superior to traditional imaging and endoscopic technique and should be considered after a negative ileocolonoscopy.Although CE has also been used for evaluating established CD,a high capsule retention rate precludes its use ahead of cross-sectional imaging.Celiac disease,particularly where gastro-duodenoscopy cannot be performed or is normal,can also be investigated by CE.Small bowel tumor,hereditary polyposis syndrome,and non-steroidal anti-inflammatory drugs induced intestinal damage are other indications for CE.Capsule retention is the only significant adverse outcome of CE and occurs mostly in presence of intestinal obstruction.This can be prevented by use of Patency capsule prior to CE examination.Presence of cardiac pacemaker and intracardiac devices continue to be relative contraindications for CE,though data do not suggest interference of CE with these devices.Major limitations of CE today include failure to control its movement from outside,inability of CE to acquire tissue for diagnosis,and lack of therapeutic help.With ongoing interesting and exciting developments taking place in these areas,these issues would be solved in all probability in near future.CE has the potential to become one of the most important tools in diagnostic and possibly in the therapeutic field of gastrointestinal disorder. | Mahesh K Goenka Shounak Majumder Usha Goenka | 2014 | World Journal of Gastroenterology2014，20，29： | 9 |
| 4 | Pre-treatment of rocks prior to comminution--A critical review of present practices显示文摘It has been an established fact that comminution processes, crushing and grinding, are most energy intensive processes which account for more than half of the total energy consumed in mineral industries.Various alternative pre-treatment methods have been tried by experts around the globe. Although these methods yielded positive results in terms of reduction in energy consumption in crushing and particularly, in grinding operations at laboratory scale, their industrial application still remains an unresolved issue and challenge. Present review paper describes each one of these methods along with outcome of earlier studies and issues that need to be addressed through further rigorous experimental investigation.It also suggests the direction in which future studies can be carried out to meet the primary objective of making comminution processes more energy efficient than today they are. | Somani Aditya Nandi Tapas K. Pal Samir K. Majumder Arun K. | 2017 | International Journal of Mining Science and Technology2017，27，2： | 7 |
| 5 | Inflammatory bowel disease-related colorectal cancer:Past,present and future perspectives显示文摘Inflammatory bowel disease-related colorectal cancer(IBD-CRC)is one of the most serious complications of IBD contributing to significant mortality in this cohort of patients.IBD is often associated with diet and lifestyle-related gut microbial dysbiosis,the interaction of genetic and environmental factors,leading to chronic gut inflammation.According to the“common ground hypothesis”,microbial dysbiosis and intestinal barrier impairment are at the core of the chronic inflammatory process associated with IBD-CRC.Among the many underlying factors known to increase the risk of IBD-CRC,perhaps the most important factor is chronic persistent inflammation.The persistent inflammation in the colon results in increased proliferation of cells necessary for repair but this also increases the risk of dysplastic changes due to chromosomal and microsatellite instability.Multiple pathways have been identified,regulated by many positive and negative factors involved in the development of cancer,which in this case follows the‘inflammation-dysplasia-carcinoma’sequence.Strategies to lower this risk are extremely important to reduce morbidity and mortality due to IBD-CRC,among which colonoscopic surveillance is the most widely accepted and implemented modality,forming part of many national and international guidelines.However,the effectiveness of surveillance in IBD has been a topic of much debate in recent years for multiple reasons—cost-benefit to health systems,resource requirements,and also because of studies showing conflicting long-term data.Our review provides a comprehensive overview of past,present,and future perspectives of IBD-CRC.We explore and analyse evidence from studies over decades and current best practices followed globally.In the future directions section,we cover emerging novel endoscopic techniques and artificial intelligence that could play an important role in managing the risk of IBD-CRC. | Snehali Majumder Uday Nagesh Shivaji Rangarajan Kasturi Alben Sigamani Subrata Ghosh Marietta Iacucci | 2022 | World Journal of Gastrointestinal Oncology2022，14，3： | 5 |
| 6 | A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration显示文摘Age-related macular degeneration(AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040.Genetics,age,diabetes,gender,obesity,hypertension,race,hyperopia,iris-color,smoking,sun-light and pyroptosis have varying roles in AMD,but oxidative stress-induced inflammation remains a significant driver of pathobiology.Eye is a unique organ as it contains a remarkable oxygengradient that generates reactive oxygen species(ROS) which upregulates inflammatory pathways.ROS becomes a source of functional and morphological impairments in retinal pigment epithelium(RPE),endothelial cells and retinal ganglion cells.Reports demonstrated that hydrogen sulfide(H_2S) acts as a signaling molecule and that it may treat ailments.Therefore,we propose a novel hypothesis that H_2S may restore homeostasis in the eyes thereby reducing damage caused by oxidative injury and inflammation.Since H_2S has been shown to be a powerful antioxidant because of its free-radicals' inhibition properties in addition to its beneficial effects in age-relatedconditions,therefore,patients may benefit from H_2S salubrious effects not only by minimizing their oxidant and inflammatory injuries to retina but also by lowering retinal glutamate excitotoxicity. | Akash K George Mahavir Singh Rubens Petit Homme Avisek Majumder Harpal S SANDhu Suresh C Tyagi | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 7 | Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice显示文摘 | Bo Wang Sarmila Majumder Gerard Nuovo Huban Kutay Stefano Volinia Tushar Patel Thomas D. Schmittgen Carlo Croce Kalpana Ghoshal Samson T. Jacob | 2009 | Hepatology2009，，4： | 3 |
| 8 | In vivo modulation of androgen receptor by androgens显示文摘Aim:To study the effect of androgen and antiandrogen on the level of androgen receptor(AR)mRNA.Methods:The totalRNA was extracted from the prostate and analyzed by slot blot analysis,The blots were hybrid-ized with ARcDNA probe and 1Aprobe(internal control)and autoradionraphy was performed.The intensity of signal was measured with a densitometer and the ratio of AR RNAand1ARNAwas calculated.Results:Androgenic deprivation produced by castration decreased the weight of the prostate and increased the levels of ARmRNA.Treatment of the castrated rats with testostrone increased the weight of prostate and decreased the levels of ARmRNA.Treatment of normal rats with flutamide decreased the weight of the gland and increased the levels of AR mRNA.Conclusion:Androgens produce proliferative effect on the prostate and negatively regulate the AR transcription. | V. L. Kumar P.K. Majumder V. Kumar | 2002 | Asian Journal of Andrology2002，4，3： | 3 |
| 9 | Molecular detection of pancreatic neoplasia: Current status and future promise显示文摘Pancreatic cancer is usually diagnosed at an advanced stage and curative resection is feasible in only a small minority of patients at the time of diagnosis. Diagnosis at an early stage is unequivocally associated with better long-term survival. Several candidate molecular markers for early detection are currently under investigation in different phases of discovery and validation. Recent advances in the technology for whole genome,methylome,ribonucleome,and proteome interrogation has enabled rapid advancements in the field of biomarker discovery. In this review we discuss the current status of molecular markers for detection of pancreatic cancer in blood,pancreatic cyst fluid,pancreatic juice and stool and briefly highlight some promising preliminary results of new approaches that have the potential of advancing this field in the near future. | Shounak Majumder Suresh T Chari David A Ahlquist | 2015 | World Journal of Gastroenterology2015，21，40： | 3 |
| 10 | Dengue epidemiology and pathogenesis:images of the future viewed through a mirror of the past显示文摘Every year, millions of individuals throughout the world are seriously affected by dengue virus. The unavailability of a vaccine and of anti-viral drugs has made this mosquito-borne disease a serious health concern. Not only does dengue cause fatalities but it also has a profoundly negative economic impact. In recent decades, extensive research has been performed on epidemiology, vector biology, life cycle, pathogenesis, vaccine development and prevention. Although dengue research is still not at a stage to suggest definite hopes of a cure, encouraging significant advances have provided remarkable progress in the fight against infection. Recent developments indicate that both anti-viral drug and vaccine research should be pursued, in parallel with vector control programs. | Rashedul Islam Mohammed Salahuddin Md.Salahuddin Ayubi Tahmina Hossain Apurba Majumder Andrew W.Taylor-Robinson Abdullah Mahmud-Al-Rafat | 2015 | Virologica Sinica2015，30，5： | 2 |
| 11 | 信号调制系统实现角位移测量(英文)显示文摘采用基于定时器LM555的非稳态多谐振荡器和通用频数转换设计了一种变面积式电容传感器信号调制系统用于角位移测量。变面积式电容器连接在基于定时器的非稳态电路内,其角位移的变化引起电容的变化,进而引起定时器电路输出时间周期的变化。定时器电路输出波形的时间周期与电容呈线性关系,因而与角位移也是线性关系。定时器输出经通用频数转换器进一步处理后可用于测量。实验结果显示,时间周期与角位移在0-180°范围内呈线性关系,将不确定度与平均时间周期相关联,即为平均标准差,亦称为标准误差,其值为±0.023μs。该测量系统使用简单,可用于电子和工业仪器中。 | Sumitesh Majumder T K Maiti | 2019 | Journal of Measurement Science and Instrumentation2019，10，1： | 2 |
| 12 | 马来西亚一所私立大学使用视觉显示装置的学生非斜视双眼视觉异常显示文摘目的:评估马来西亚一所私立大学使用视觉显示装置(VDU)的学生非斜视双眼视觉异常(NSBVA)情况。方法:对2019-01/2019-05期间每天使用3h及以上VDU的大学生进行横断面研究。使用一种简便的样本收集方法,所有受试者均通过初级视力检查且满足入选标准,对符合入选标准的学生进一步进行NSBVA评估。采用描述性分析排除NSBVA的百分比,采用Chi-square独立性检验,观察NSBVA与年龄、性别、VDU使用时间的相关性。结果:研究共纳入140名学生,其中女88名(62.9%),男52名(37.1%)。受试者平均年龄为22.54±1.48a,平均VDU使用时间为5.76±2.49h。使用VDU学生的NSBVA百分比为40%。在VDU使用者中,调节异常和倾斜异常的发生率分别为17.86%和22.14%。性别与NSBVA之间存在适度关联(P=0.010)。但是,年龄(P=0.334)和VDU使用时间(P=0.835)与NSBVA无显著相关。结论:马来西亚一所私立大学的学生中,有40%的人使用VDU。在所有NSBVA中,VDU用户调节异常(15%)和会聚功能异常(10%)更为常见。 | Chiranjib Majumder Toh Ching Ling | 2020 | 国际眼科杂志2020，20，6： | 2 |
| 13 | Bearing and uplift capacities of under-reamed piles in soft clay underlaid by stiff clay using lower-bound finite element limit analysis显示文摘Ensuring a safe foundation design in soft clay is always a challenging task to engineers.In the present study,the effectiveness of under-reamed piles in soft clay underlaid by stiff clay is numerically studied using the lower-bound finite element limit analysis(LB FELA).The bearing and uplift capacities of under-reamed piles are estimated through non-dimensional factors N_(cul)and Fcul,respectively.These factors increased remarkably and marginally compared to N_(cul)and Fcul of the piles without bulbs when the bulb is placed in stiff and soft clay,respectively.For a given ratio of undrained cohesion of stiff to soft clay(c_(2)/c_(1)),the factors N_(cul)and Fcul moderately increased with the increase in the length-to-shaft-diameter ratio(Lu/D)and adhesion factors in soft clay(α_(s1))and stiff clay(αs2).The variation of radial stress along the pile-soil interface,distribution of axial force in the under-reamed piles,and state of plastic shear failure in the soil are also studied under axial compression and tension.The results of this study are expected to be useful for the estimation of the bearing and uplift capacities of under-reamed piles in uniform clay and soft clay underlaid by stiff clay. | Mantu MAJUMDER Debarghya CHAKRABORTY | 2021 | Frontiers of Structural and Civil Engineering2021，15，2： | 2 |
| 14 | Hydrogen sulfide intervention in cystathionine-β-synthase mutant mouse helps restore ocular homeostasis显示文摘AIM: To investigate the applications of hydrogen sulfide(H2 S) in eye-specific ailments in mice.METHODS: Heterozygous cystathionine-β-synthase(CBS+/-) and wild-type C57 BL/6 J(WT) mice fed with or without high methionine diet(HMD) were administered either phosphate buffered saline(PBS) or the slow-release H2 S donor: GYY4137. Several analyses were performed to study GYY4137 effects by examining retinal lysates for key protein expressions along with plasma glutamate and glutathione estimations. Intraocular pressure(IOP) was monitored during GYY4137 treatment; barium sulfate and bovine serum albumin conjugated fluorescein isothiocyanate(BSA-FITC) angiographies were performed for examining vasculature and its permeability post-treatment. Visionguided behavior was also tested employing novel object recognition test(NORT) and light-dark box test(LDBT) recordings.RESULTS: CBS deficiency(CBS+/-) coupled with HMD led disruption of methionine/homocysteine(Hcy) metabolism leading to hyperhomocysteinemia(HHcy) in CBS+/-mice as reflected by increased Hcy, and s-adenosylhomocysteine hydrolase(SAHH) levels. Unlike CBS, cystathionine-γ lyase(CSE), methylenetetrahydrofolate reductase(MTHFR) levels which were reduced but compensated by GYY4137intervention. Heightened oxidative and endoplasmic reticulum(ER) stress responses were mitigated by GYY4137 effects along with enhanced glutathione(GSH) levels. Increased glutamate levels in CBS+/-strain were prominent than WT mice and these mice also exhibited higher IOP that was lowered by GYY4137 treatment. CBS deficiency also resulted in vision-guided behavioral impairment as revealed by NORT and LDBT findings. Interestingly, GYY4137 was able to improve CBS+/-mice behavior together with lowering their glutamate levels. Blood-retinal barrier(BRB) appeared compromised in CBS+/-with vessels' leakage that was mitigated in GYY4137 treated group. This corroborated the results for occludin(an integral plasma membrane protein of the cellular tight junctions) stabilization.CONCLUSION: Findings reveal that HHcy-induced glutamate excitotoxicity, oxidative damage, ER-stress and vascular permeability alone or together can compromise ocular health and that GYY4137 could serve as a potential therapeutic agent for treating HHcy induced ocular disorders. | Akash K.George Rubens P.Homme Avisek Majumder Anwesha Laha Naira Metreveli Harpal S.SANDhu Suresh C.Tyagi Mahavir Singh | 2019 | International Journal of Ophthalmology(English edition)2019，12，5： | 2 |
| 15 | Biofiltration and kinetic aspects of a biotrickling filter for the removal of paint solvent mixture laden air stream 显示文摘 | Mathur A K Majumder C D | 2008 | J Hazard Mater2008，152，： | 1 |
| 16 | Crepidatin, a bibenzyl derivative from the orchid Dendrobiun crepidatum 显示文摘 | Chatterjee S | 1989 | Phytochemistry1989，28，7： | 1 |
| 17 | Effects of trochanteric soft tissue thickness and hip impact velocity on hip fracture in sideways fall through 3 D finite element simulations 显示文摘 | Majumder S Roychowdhury A Pal S | 2008 | J Biomechanics2008，41，： | 1 |
| 18 | Competition in remanufaeturing显示文摘 | Majumder P Groenevelt H | 2001 | Production Operational Management2001，10，： | 1 |
| 19 | Competition in remanufacturing 显示文摘 | Majumder P Groenevelt H | 2001 | Production and Operations Management2001，10，2： | 1 |
| 20 | Combined removal of BTEX in air stream by using mixture of sugar cane bagasses, compost and GAC as biofiher media 显示文摘 | Mathur A K Majumder C B Chatterjee S | 2007 | Journal of Hazardous Materials2007，148，12： | 1 |
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