| 1 | Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients显示文摘OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.METHODS:One hundred migraine patients and 46 healthy subjects were recruited.Patients were randomized into the acupuncture,sham acupuncture,and waiting list groups.Resting-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture treatments.Fractional amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list group.RESULTS:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular gyrus.Regression analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this group.CONCLUSION:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment. | Li Zhengjie Zhou Jun Cheng Shirui Lan Lei Sun Ruirui Liu Mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang Liang Fanrong | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 5 |
| 2 | A central analgesic mechanism of acupuncture for migraine An ongoing functional MRI study显示文摘Shaoyang acupoints are the most frequently used in migraine treatment.However,the central analgesic mechanism remains poorly understood.Studies have demonstrated that single stimulus of the verum acupuncture in healthy subjects can induce significant connectivity or activity changes in painrelated central networks compared with sham acupuncture.However,these findings are not indicative of the central analgesic mechanism of acupuncture at Shaoyang acupoints.Thus,we recruited 100migraine sufferers and randomly assigned them into five groups:Shaoyang uncommon acupoint,Shaoyang common acupoint,Yangming uncommon acupoint,non-acupoint control,and blank control groups.Subjects were subjected to evaluation of curative effects and functional MRI prior to and after10 and 20 acupuncture treatments.All subjects were diagnosed by physicians and enrolled following clinical physical examination.Subjects were observed during 1–4 weeks after inclusion.At the fifth week,the first clinical evaluation and resting functional MRI were conducted.The Shaoyang uncommon acupoint,Shaoyang common acupoint,Yangming uncommon acupoint,and non-acupoint control grousp then were treated with acupuncture,five times per week,20 times in total over 4 weeks.The second and third clinical evaluations and resting functional MRI screenings were conducted following10 and 20 acupuncture treatments.The blank control group was observed during the 5 to 8 week period,followed by clinical evaluation and resting functional MRI.The aim of this study was to examine changes in brain functional activity and central networks in subjects with migraine undergoing acupuncture at Shaoyang uncommon acupoints.This study provides a further explanation of the central analgesic mechanism by which acupuncture at Shaoyang acupoints treats migraine. | Lei Lan Yujie Gao Fang Zeng Wei Qin Mingkai Dong Mailan Liu Taipin Guo Fanrong Liang | 2013 | Neural Regeneration Research2013，8，28： | 3 |
| 4 | An acupuncture meta-analysis for optic atrophy Seven randomized,controlled trials显示文摘OBJECTIVE: To evaluate the efficacy and safety of acupuncture for optic atrophy.DATA SOURCES: A computer-based online search was conducted in Medline (1966-2008),Embase (1986-2008), the Cochrane Library (up to 2008), Chinese Biomedical Literature Database(1975-2008), China National Knowledge Infrastructure (1994-2008), VIP Database (1989-2008),Wanfang Database (1980-2008) and the National Research Register for ongoing trials.DATA SELECTION: Randomized, controlled trials addressing acupuncture treatment for patientswith optic atrophy were included in this review. Inclusion criteria evaluated all forms of acupuncturetherapy, such as filiform needle, electro-acupuncture, laser-acupuncture, acupressure, andauricular-acupuncture. Comparisons between acupuncture therapy and no treatment (blank) orplacebo or Chinese medicine or Western medicine, as well as between acupuncture as an adjuvantand other treatments, were included. Exclusion criteria included studies comparing different forms ofacupuncture therapy, different manipulations of acupuncture, and different acupunctureprescriptions, as well as non-randomized, controlled trials and animal studies. The domain-basedevaluation criteria recommended by the guidelines in Chapter 8 of the Cochrane Handbook forSystematic Reviews of Interventions 5.0.1 was used to assess quality of the included studies.According to the type of outcome index, measurement data as assessed by weighted meandifference or standardized mean difference and 95% confidence interval; numeration data wasestimated by relative risk and 95% confidence interval. Heterogeneity was analyzed byMeta-analysis using RevMan 5.0 software.MAIN OUTCOME MEASURES: Improved visual acuity and visual field was sought betweentreatment and control groups in the included articles.RESULTS: Seven randomized, controlled trials were included after screening and application ofinclusion and exclusion criteria. However, the studies were of low methodological quality and lackedcomparisons between acupuncture and no treatment or placebo. Applying visual acuity as theoutcome index, meta-analysis indicated: the effect of medicine combined with acupuncture wassuperior to the medicine alone (relative risk = 1.41,95% confidence interval 1.14-1.70, P < 0.01),the efficacy of acupuncture was better than medicine alone (relative risk =1.42, 95% confidenceinterval 1.14-1.77, P < 0.01). Using visual field as the other outcome index, meta-analysis revealed:effectiveness of acupuncture or acupuncture in combination with medicine was superior to medicinealone (relative risk = 1.47, 95% confidence interval 1.27-1.69, P < 0.01 ). The 7 included articleswere incorporated in a sensitivity analysis, and the overall effect showed a significant difference(relative risk = 1.35, 95% confidence interval 1.16-1.56, P < 0.01). Acupuncture was not associatedwith any adverse events in any of the studies.CONCLUSION: Acupuncture therapy was determined to be superior to medicine in terms ofimproved visual acuity and visual field. However, well-designed, randomized, controlled trials withadequate controls and scientific rigor are urgently needed. | Mailan Liu Lei Lan Yong Tang Fang Zeng Haiyan Yin Mei Huang Fanrong Liang | 2009 | Neural Regeneration Research2009，4，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员