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| 1 | 人血浆硫氧化还原蛋白80随着年龄增长而增加,并在载脂蛋白E基因敲除小鼠中诱导炎症、血管生成和动脉粥样硬化显示文摘硫氧化还原蛋白(thioredoxin,TRX)1是一种普遍存在的12kD的蛋白质,可产生抗氧化和抗炎作用。由巨噬细胞产生的截断形式称为TRX80,其可诱导促炎细胞因子的上调。TRX80还促进小鼠腹膜和人巨噬细胞向促炎M1表型的分化。方法:使用特异性酶联免疫吸附试验测定血浆TRX1和TRX80水平。 | 刘莉 叶鹏 Couchie D Vaisman B Abderrazak A Mahmood DFD Hamza MM Canesi F Diderot V El Hadri K Nègre-Salvayre AE Le Page A Fulop T Remaley AT Rouis M | 2017 | 中华高血压杂志2017，25，6： | 9 |
| 2 | Differential reactivity of mouse monoclonal anti-HBs antibodies with recombinant mutant HBs antigens显示文摘AIM: To investigate the reactivity of a panel of 8 mouse anti-hepatitis B surface antigen (HBsAg) monoclonal antibodies (mAbs) using a collection of 9 recombinant HBsAg mutants with a variety of amino acid substitutions mostly located within the “a” region.METHODS: The entire HBs genes previously cloned into a mammalian expression vector were transiently transfected into COS7 cells. Two standard unmutated sequences of the ayw and adw subtypes served as controls. Secreted mutant proteins were collected and measured by three commercial diagnostic immunoassays to assess transfection efficiency. Reactivity of anti-HBs mAbs with mutated HBsAgs was determined by sandwich enzyme-linked immunosorbent assay (ELISA).RESULTS: Reactivity of anti-HBs mAbs with mutated HBsAgs revealed different patterns. While three mutants reacted strongly with all mAbs, two mutants reacted weakly with only two mAbs and the remaining proteins displayed variable degrees of reactivity towards different mAbs. Accordingly, four groups of mAbs with different but overlapping reactivity patterns could be envisaged. One group consisting of two mAbs (37C5-S7 and 35C6-S11) was found to recognize stable linear epitopes conserved in all mutants. Mutations outside the “a” determinant at positions 120 (P→S), 123(T→N) and 161(M→T) were found to affect reactivity of these mAbs.CONCLUSION: Our findings could have important implications for biophysical studies, vaccination strategies and immunotherapy of hepatitis B virus (HBV) mutants. | Azam Roohi Yaghoub Yazdani Jalal Khoshnoodi Seyed Mohammad Jazayeri William F Carman Mahmood Chamankhah Manley Rashedan Fazel Shokri | 2006 | World Journal of Gastroenterology2006，12，33： | 4 |
| 3 | Rescue of influenza B virus from eight plasmids显示文摘 | Hoffmann E Mahmood K Yang C F | 2002 | Proc Natl Acad Sci USA2002，99，11： | 2 |
| 4 | Soil moisture: A central and unifying theme in physical geography显示文摘 | Legates David R Mahmood Rezaul Levia Delphis F DeLiberty Tracy L Quiring Steven M Houser Chris Nelson Frederick E | 2011 | Progress in Physical Geography2011，，1： | 2 |
| 5 | Soil mois- ture: A central and unifying theme in physical geography 显示文摘 | Legates David R Mahmood R Levia Delphis F | 2011 | Pro- gress in Physical Geography2011，35，1： | 1 |
| 6 | Molecu- lar differentiation between two varieties of Ros- marinus officinal grown in north east region of I- raq显示文摘 | Ibrahim K M Mahmood T N Barazanchi F M | 2011 | Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Horticulture2011，68，1： | 1 |
| 7 | Study on biosorption of humic acid by activated sludge 显示文摘 | Feng H J Hu L F Mahmood Q et ol | 2008 | Bioehem Eng J2008，39，3： | 1 |
| 8 | A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperatire optical brain tumor delineation 显示文摘 | Moritz F Mahmood U Raymond S | 2003 | Cancer Res2003，63，23： | 1 |
| 9 | Thoracic spinal epidural lipomatosis associated with adoles- cent scoliosis显示文摘 | Sabharwal S Mahmood F | 2006 | Journal of spinal disorders & techniques2006，19，3： | 1 |
| 10 | Tifacogin,recombinant tissue factor pathway inhibitor 显示文摘 | Matyal R Mahmood F Park KW | 2005 | Int Anesthesiol Clin2005，43，2： | 1 |
| 11 | Study on biosorption of humic acid by activated sludge显示文摘 | FENG H J HU L F MAHMOOD Q | 2008 | Biochemical Engineering Journal2008，39，47： | 1 |
| 12 | Diagnosrici-magingtech-miquesimthyroidcaner显示文摘 | Toriumi D Mahmood F | 1988 | Am J Surg1988，155，2： | 1 |
| 13 | Continuous perioperative insulin infusion decreases major cardiovas- cular events in patients undergoing vascular surgery: a prospective, ran- domized trial显示文摘 | Subramaniam B Panziea PJ Novack V Mahmood F Matyal R Mitchell JD Sundar E Bose R Pomposelli F Kersten JR Talmor DS | 2009 | Anesthesiology2009，23，5： | 1 |
| 14 | An evaluation of four reference evapotranspiration models in a subtropical climate显示文摘 | ALI R MAHMOOD R B JAVAD F | 2012 | Water Resource Manage2012，26，： | 1 |
| 15 | A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoprative optical brain tumor delineation 显示文摘 | Mortiz F Mahmood U Raymond S | 2003 | Cancer Res2003，63，23： | 1 |
| 16 | The inhibition of prostaglandin biosynthesis by human haptoglobin and its relationship with haemoglobin binding显示文摘 | Saeed SA Mahmood F Shall BH | 1997 | Biochem Soc Trans1997，25，4： | 1 |
| 17 | Evolution of optical solitons in nonlinear dispersive lossy fibers显示文摘 | Mahmood M F | 2001 | Opt And Las Tech2001，33，： | 1 |
| 18 | Fluid Dynam- ics of a Pre-Swirl Rotor- Stator System 显示文摘 | Yah Youyou Mahmood F G Gary D L | 2003 | ASME Jour- nal of Turbomachinery2003，125，1： | 1 |
| 19 | Nanostructured electrode materials derived from metal-organic framework xerogels for high-energy-density asymmetric supercapacitor显示文摘 | MAHMOOD A ZOU R Q WANG Q F | 2016 | ACS Applied Materials&Interfaces2016，8，3： | 1 |
| 20 | Preoperative imaging anatomy of nasal ethmoid complex for Funetionl endoscopic sinus surgery显示文摘 | Mahmood F and Mafee MD | 1993 | The Radiologic Clinics of North America1993，31，1： | 1 |
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