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| 1 | The membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin 显示文摘 | Monferran S Muller M Mourey L | 2004 | J Mol Biol2004，337，3： | 1 |
| 2 | Unique behavior of dendritic macromolecules:intrinsic viscosity of polyether dendrimers显示文摘 | FRECHET J M J WOOLEY K L | 1992 | Macromol1992，25，9： | 1 |
| 3 | Unique behavior of dendritic macromolecules:intrinsic viscosity of polyether dendrimers显示文摘 | TH Mourey SR Turner M Rubinstein | 1992 | Macromolecules1992，25，： | 1 |
| 4 | Latissimus dorsi tendontransfer for irreparable rotator cuff tears : a modified technique toimprove tendon transfer integrity 显示文摘 | Mourey M Forstner R Koller H | 2009 | J Bone Joint Surg Am2009，91，8： | 1 |
| 5 | New phase noise model for crystal oscillators application to the Clapp oscillator显示文摘 | GALLIOU S STHAL F MOUREY M | 2003 | IEEE Trans Ultrason Ferroelectr Freq Control2003，50，11： | 1 |
| 6 | Unique be- havior of dendritic macromo|ecules: intrinsic viscosity of polyether dendrimers 显示文摘 | MOUREY T H TURNER S R RUB1NSTEIN M | 1992 | Macromolccules1992，25，9： | 1 |
| 7 | CT diagnosis of ureteral fibroepithelial polyps显示文摘 | BELLIN M F SPRINGER O MOUREY GEROSA I | 2002 | Eur Radiol2002，12，1： | 1 |
| 8 | Unique behavior of dendritic macromolecules: intrinsic viscosity of polyether dendrimers 显示文摘 | Mourey T H Turner S R Rubinstein M Fr6ehet J M J Hawker C J Wooley K L | 1992 | Macromolecules1992，25，9： | 1 |
| 9 | Unique behavior of dendritic macromolecules: intrinsic viscosity of polyether dendrlmers 显示文摘 | Mourey T H Turner S R Rubinstein M | 1992 | Macromolecules1992，25，： | 1 |
| 10 | Thin- section chest CT findings of primary Sjogren's syndrome: correlation with pulmonary function 显示文摘 | Taouli B Brauner M W Mourey I | 2002 | Eur Radiol2002，12，6： | 1 |
| 11 | Temperature processing of an ultra stable quartz oscillator显示文摘 | Galliou S Mourey M | 2001 | IEEE Trans Ultrason Ferroelectr Freq Control2001，48，： | 1 |
| 12 | Saccharomyces cerevisiae prevents postoperative recurrence of Crohn's disease modeled by ileocecal resection in HLA-B27 transgenic rats显示文摘BACKGROUND Postoperative recurrence(POR)after ileocecal resection(ICR)affects most Crohn's disease patients within 3-5 years after surgery.Adherent-invasive Escherichia coli(AIEC)typified by the LF82 strain are pathobionts that are frequently detected in POR of Crohn's disease and have a potential role in the early stages of the disease pathogenesis.Saccharomyces cerevisiae CNCM I-3856 is a probiotic yeast reported to inhibit AIEC adhesion to intestinal epithelial cells and to favor their elimination from the gut.AIM To evaluate the efficacy of CNCM I-3856 in preventing POR induced by LF82 in an HLA-B27 transgenic(TgB27)rat model.METHODS Sixty-four rats[strain F344,38 TgB27,26 control non-Tg(nTg)]underwent an ICR at the 12th wk(W12)of life and were sacrificed at the 18th wk(W18)of life.TgB27 rats were challenged daily with oral administration of LF82(109 colony forming units(CFUs)/day(d),n=8),PBS(n=5),CNCM I-3856(109 CFUs/d,n=7)or a combination of LF82 and CNCM I-3856(n=18).nTg rats receiving LF82(n=5),PBS(n=5),CNCM I-3856(n=7)or CNCM I-3856 and LF82(n=9)under the same conditions were used as controls.POR was analyzed using macroscopic(from 0 to 4)and histologic(from 0 to 6)scores.Luminal LF82 quantifications were performed weekly for each animal.Adherent LF82 and inflammatory/regulatory cytokines were quantified in biopsies at W12 and W18.Data are expressed as the median with the interquartile range.RESULTS nTg animals did not develop POR.A total of 7/8(87%)of the TgB27 rats receiving LF82 alone had POR(macroscopic score≥2),which was significantly prevented by CNCM I-3856 administration[6/18(33%)TgB27 rats,P=0.01].Macroscopic lesions were located 2 cm above the anastomosis in the TgB27 rats receiving LF82 alone and consisted of ulcerations with a score of 3.5(2-4).Seven out of 18 TgB27 rats(39%)receiving CNCM I-3856 and LF82 had no macroscopic lesions.Compared to untreated TgB27 animals receiving LF82 alone,coadministration of CNCM I-3856 and LF82 significantly reduced the macroscopic[3.5(2-4)vs 1(0-3),P=0.002]and histological lesions by more than 50%[4.5(3.3-5.8)vs 2(1.3-3),P=0.003].The levels of adherent LF82 were correlated with anastomotic macroscopic scores in TgB27 rats(r=0.49,P=0.006),with a higher risk of POR in animals having high levels of luminal LF82(71.4%vs 25%,P=0.02).Administration of CNCM I-3856 significantly reduced the levels of luminal and adherent LF82,increased the production of interleukin(IL)-10 and decreased the production of IL-23 and IL-17 in TgB27 rats.CONCLUSION In a reliable model of POR induced by LF82 in TgB27 rats,CNCM I-3856 prevents macroscopic POR by decreasing LF82 infection and gut inflammation. | Caroline Valibouze Silvia Speca Caroline Dubuquoy Florian Mourey Lena M'Ba Lucil Schneider Marie Titecat Benoît Foligné Michaël Genin Christel Neut Philippe Zerbib Pierre Desreumaux | 2023 | World Journal of Gastroenterology2023，29，5： | 1 |
| 13 | Unique behavior of dendritic macromolecules: intrinsic viscosity of polyether dendrimers 显示文摘 | Mourey T H Ttumer S R Frecthct J M J | 1992 | Macromolecules1992，25，9： | 1 |
| 14 | Unique Behavior of Dendritic Macromolecules: Intrinsic Viscosity of Polyether Dendrimer 显示文摘 | Mourey T H Turner S R Rubinstein M | 1992 | Macromolecules1992，25，9： | 1 |
| 15 | The molecular puzzle of two-component signaling cascades显示文摘 | Foussard M Cabantous S Pédelacq J Guillet V Tranier S Mourey L Birck C Samama J | 2001 | Microbes and Infection2001，3，5： | 1 |
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