|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017，6，1： | 6 |
| 2 | 补体B因子是代谢综合征模型代谢与心血管特征的一个决定因素显示文摘补体B因子(complenment factor B,CFB)在2型糖尿病及心血管病患者脂肪组织及血清中水平升高,但与疾病发病机制的因果关系不明确。自发性高血压大鼠(spontaneously hypertensive rats,SHR)脂肪组织及血清中CFB也升高。为明确CFB在代谢综合征中的作用,研究者在SHR中敲除Cfb基因。 | 赵狄 练桂丽 Coan PM Barrier M Alfazema N Carter RN Marion de Procé S Dopico XC Garcia Diaz A Thomson A Jackson-Jones LH Moyon B Webster Z Ross D Moss J Arends MJ Morton NM Aitman TJ | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 3 | Phenotypic analysis of antigen-specific T lymphocytes显示文摘 | Moss P A H Goulter P J R | 1996 | Science1996，274，： | 1 |
| 4 | Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome:A worldwide report显示文摘 | SCHWARTZ P J LOCATI E H MOSS A J | 1991 | Circulation1991，84，2： | 1 |
| 5 | The membrane fusion step of vaccinia virus entry is cooperatively mediated by multiple viral proteins and host cell components 显示文摘 | LALIBERTE J P WEISBERG A S MOSS B | 2011 | Plns Pathog2011，7，12： | 1 |
| 6 | The behavior of bearings used for seismic isolation under shear and axial load 显示文摘 | P J Moss N Cook A J Carr | 1999 | Earthquake Spectra1999，15，2： | 1 |
| 7 | Use of a silicone dual-lumen catheter with a Dacron cuff as a longterm vascular access for hemodialysis patient显示文摘 | MOSS A H VASILAKIS C HOLLEY J L | 1990 | Am J Kidney Dis1990，16，3： | 1 |
| 8 | Artifi-cial photosynthesis : semiconductor photocatalytic fixa-tion of C02 to afford higher organic compounds显示文摘 | HOFFMANN M R MOSS J A BAUM M M | 2011 | Dal-ton Transactions2011，40，19： | 1 |
| 9 | Cardiac-resyn- chronization therapy for the prevention of heart-failure events显示文摘 | Moss A J Hall WJ Cannom DS | 2009 | N Engl J Med2009，361，14： | 1 |
| 10 | Cardiac-resynchronization therapy for the prevention of heart-failure events显示文摘 | Moss A J Hall W J Cannom D S | | 0，，14： | 1 |
| 11 | The next generation of scenarios for climate change research and assessment 显示文摘 | MOSS R H EDMONDS J A HIBBARD K A | 2010 | Nature2010，463，7282： | 1 |
| 12 | Cardiac-resynchronization therapy for the prevention of heart-failure events 显示文摘 | Moss A J Hall WJ Cannom DS | 2009 | N Engl J Med2009，361，14： | 1 |
| 13 | Design Method for Bridges on Lead-rubber Bearings显示文摘 | Turkington D H Carr A J Cooke N Moss P J | 1989 | Journal of Structural Engineering1989，115，12： | 1 |
| 14 | Dispersion of ventricular replorization and arrhythmic cardiac death in coronary artery disease显示文摘 | Moss A J Lecessie S | 1994 | Am J Cardiol1994，74，6： | 1 |
| 15 | Assessment of poste- rior spinal cord function with electrical perception thresh-old in spinal cord injury显示文摘 | Kramer JL Moss A J Taylor P | 2008 | J Neurotrauma2008，25，8： | 1 |
| 16 | Phenotypic analysis of antigenspecific T lymphocytes 显示文摘 | Altman J D Moss P A Geulder P J | 1996 | Science1996，274，5284： | 1 |
| 17 | The next generation of scenarios for climate change research and assessment 显示文摘 | MOSS R H EDMONDS J A HIBBARD K A | 2010 | Nature2010，463，7282： | 1 |
| 18 | Associations between task, training and social environmental factors and error types involved in rail incidents and accidents 显示文摘 | Read G J Lenne M G Moss S A | 2012 | Acci- dent Analysis & Prevention2012，，： | 1 |
| 19 | Erosive effects of the large water drops(gravity drops) that fall from plants显示文摘 | Moss A J Green T W | 1987 | Australian Journal of Soil Research1987，25，： | 1 |
| 20 | Phenotypic analysis of antigen-specific T lymphocytes显示文摘 | Altaian J D Moss P A H Goulder P J R | 1996 | Science1996，274，5284： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员