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| 1 | DESIS国际网络:可持续和社会创新的设计显示文摘2010年9月7-10日,Cumulus国际设计院校联盟大会将在上海召开,它在与DESIS国际联盟合作的基础上,将'可持续与社会创新设计'作为会议分主题之一。9月10日,DESIS国际论坛和DESIS-国际联盟会议将在世博会联合国馆举行。9月12日,DESIS国际研讨会'为地方发展的社会创新设计'将在江南大学设计学院举办。9月13-18日,意大利米兰理工大学与江南大学再次联手合作组织主题为'新农村、新城市、新生活'的食品网络设计工作坊。在九月份连续几个以'可持续与社会创新设计'为主题的国际论坛及工作坊即将开展的背景下,本刊编辑部约请了参会的Cumulus国际设计院校联盟以及DESIS国际联盟内的若干重量级嘉宾,为本刊第四期'可持续与社会创新设计'专题提供论文。本专题共8篇文章,分别从DESIS国际网络介绍,以及DESIS组织在中国、法国、中东、巴西等地区推广'可持续与社会创新设计'的具体项目出发,将'可持续与社会创新设计'从理论呼吁走向了设计实践探索,对中国当代可持续与社会创新设计的发展极具启发意义。 | Ezio Manzini Lara Penin Carla Cipolla Mugendi K.M'Rithaa Andrea Mendoza Francois Jegou Adital Ela 张桢 | 2010 | 创意与设计2010，，4： | 7 |
| 2 | Efficacy and safety of on demand tadalafil in the treatment of East and Southeast Asian men with erectile dysfunction:a randomized double-blind,parallel,placebo-controlled clinical study显示文摘瞄准:与安慰剂相比估计 tadalafil 的功效和安全,当与可勃起的机能障碍(编辑) 由东方 / 东南亚洲人呈现对 12 个星期的需求时。方法:这多集中,使随机化,双窗帘,平行的组,控制安慰剂的学习越过在 2002 年 8 月和 2003 年 2 月之间的东方和东南亚洲在 17 个中心被进行。人们超过 18 岁与对各种各样的病原学的严重编辑温和被使随机化收到安慰剂或是需要拿的 tadalafil 的 20 mg (最大从前每日) 。功效评价包括了可勃起的功能,性相遇侧面日记和全球评价问题的国际索引。结果:Tadalafil 显著地作为与安慰剂相比改进了可勃起的功能(P <
0.001 ) 。在端点,收到 tadalafil 的 20 mg 的病人每成功的交际尝试的耐心的百分比报导了一个更大的平均数(性相遇侧面问题 3:70.9% 与 33.5% 相比在安慰剂) 并且改进勃起的一个更大的比例(全球评价问题:86.2% 与 30.1% 相比) 。大多数(=/<3%) 治疗突现的不利事件温和或中等。最普通的治疗突现的不利事件是头疼,背疼痛,头昏和消化不良。结论:Tadalafil 是为在东方和东南亚洲人男人的编辑的有效、容忍得好的治疗。 | Wai Chun Andrew Yip Han-Sun Chiang Jesus Benjamin Mendoza Hui-Meng Tan Man-Kay Li Wei Christine Wang Vladimir Kopernicky | 2006 | Asian Journal of Andrology2006，8，6： | 6 |
| 3 | High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease显示文摘AIM:To examine the detection rate of viable Mycobacterium avium subspecies paratuberculosis(MAP) in patients with inflammatory bowel disease [Crohn's disease(CD) and ulcerative colitis(UC)].METHODS:Thirty patients with CD(15 with at least one NOD2/CARD15 mutation),29 with UC,and 10 with no inflammatory bowel disease(IBD).were tested for MAP by polymerase chain reaction(specific IS900 fragment) and blood culture.RESULTS:MAP DNA was detected in all original blood samples and 8-wk blood cultures(CD,UC and non-IBD).Positive MAP DNA status was confirmed by dot blot assays.All 69 cultures were negative by acid-fast Ziehl-Neelsen staining.Viable MAP,in spheroplast form,was isolated from the 18-mo blood cultures of all 30 CD patients,one UC patient,and none of the non-IBD controls.No association was found between positive MAP cultures and use of immunosuppressive drugs or CDassociated single nucleotide polymorphisms.CONCLUSION:MAP is widely present in our area and MAP DNA can be recovered from the blood of CD,UC and non-IBD patients.However,MAP spheroplasts were only found in CD patients. | Juan L Mendoza Amparo San-Pedro Esther Culebras Raquel Cíes Carlos Taxonera Raquel Lana Elena Urcelay Fernando de la Torre Juan J Picazo Manuel Díaz-Rubio | 2010 | World Journal of Gastroenterology2010，16，36： | 5 |
| 4 | Coexistence of papillary thyroid microcarcinoma and mucosa-associated lymphoid tissue lymphoma in a context of Hashimoto's thyroiditis显示文摘Papillary thyroid cancer(PTC)represents 80%-85%of thyroid cancer and its prevalence has been rising in the last decades.Primary thyroid lymphoma(PTL)accounts for 3%of extranodal lymphomas and about 5%of thyroid malignancies,having a prevalence of one or two cases per million people.Mucosa-Associated Lymphoid Tissue lymphoma represents approximately30%of PTL.Both entities have an indolent course and a very good prognosis.Diagnosis is made by ultrasound and fine needle aspiration(FNA)or surgery specimen pathology.They have also been associated with Hashimoto’s thyroiditis(HT),but pathogenesis and its links remains to be known.Treatment remains controversial and surgery is generally accepted in cases of disease limited to thyroid,as the present.Patients with thyroid nodules should be observed and followed.If there is an enlargement by ultrasound or clinical symptoms,FNA should be performed promptly.Patients with HT deserve additional surveillance,since this condition is associated with both PTC and PTL.In this case,the management with surgery and radioactive iodine ablation therapy was effective for both entities.Patients with thyroid nodules should be properly evaluated with ultrasound and thyroid function tests.If there is an enlargement of the neck,reported by symptoms or ultrasound,it requires further investigation.HT is associated to both PTC and PTL so if the enlargement of the nodules is on this context additional tests such as FNA should be performed.In this case,the patient was managed with surgery and radioactive iodine ablation therapy and it was effective for both entities. | Saul Levy-Blitchtein Stefany Plasencia-Rebata Domingo Morales Luna Juana del Valle Mendoza | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，8： | 5 |
| 5 | Behavior of diatomaceous soil in lacustrine deposits of Bogota, Colombia显示文摘This work presents a study on the behaviors of diatomaceous soils. Although studies are rarely reported on these soils, they have been identified in Mexico City, the Sea of Japan, the northeast coast of Australia,the equatorial Pacific, and the lacustrine deposit of Bogota(Colombia), among other locations. Features of this kind of soil include high friction angle, high initial void ratio, high compressibility index, high liquid limit, and low density. Some of these features are counterintuitive from a classical soil mechanics viewpoint. To understand the geotechnical properties of the diatomaceous soil, a comprehensive experimental plan consisting of more than 2400 tests was performed, including physical tests such as grain size distribution, Atterberg limits, density of solid particles, and organic matter content; and mechanical tests such as oedometric compression tests, unconfined compression tests, and triaxial tests.Laboratory tests were complemented with scanning electron microscope(SEM) observations to evaluate the microstructure of the soil. The test results show that there is an increase in liquid limit with increasing diatomaceous content, and the friction angle also increases with increasing diatomaceous content. In addition, several practical correlations were proposed for this soil type for shear strength mobilization and intrinsic compression line. Finally, useful correlations were presented, such as the relationship between the state consistency and the undrained shear strength, the friction angle and the liquid limit, the void ratio at 100 kPa and the liquid limit, the plasticity index and the diatomaceous content, among others. | Bernardo Caicedo Cristhian Mendoza Fernando López Arcesio Lizcano | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，2： | 5 |
| 6 | Changes in the sorption, desorption, distribution, and availability of copper, induced by application of sewage sludge on Chilean soils contaminated by mine tailings显示文摘The effect of mine tailings and sewage sludge was evaluated on sorption, desorption, availability and distribution of copper in two soils, one high (sandy soil) and one low in copper (clay soil). In both soils contaminated by mine tailings the copper sorption capacity and the affinity of the substrate for the metal decreased substantially compared to the uncontaminated soils, however, the sorption remained always high in the clay soil substrates. In the substrates with sandy soil, the high Cu content and lower clay content were determining factors in the lower magnitude of the sorption. Similarly, metal desorption was closely related to these two parameters, and it was higher in clay soil with lower pH. In general, the application of sewage sludge favored the sorption of Cu in soils contaminated and uncontaminated with mine tailings, and in all cases desorption decreased, an effect that remained for at least 30 days. Simple extraction of Cu with CaCl2 and diethylenetriaminepentaacetic acid gave contradictory results, so a careful choice of the procedure is required, depending on the level of metal in the soil and on the acting principle of the extracting agent. In that relation, more complete information on the changes in the metal forms was obtained by application of the sequential extraction procedure proposed by the European Community Bureau of Reference. | Tatiana Garrido Jorge Mendoza Francisco Arriagada | 2012 | Journal of Environmental Sciences2012，24，5： | 5 |
| 7 | 2019年全球城市指数报告显示文摘2019年5月30日(北京),国际管理咨询公司科尔尼发布2019全球城市指数报告,揭晓了全球最具竞争力的城市和全球最具发展潜力的城市,并指出决定城市竞争力的最大差异化因素是:“人”。吸引并留住人力资本能够使城市处于领先地位,并加速其成功。报告特别指出了人力资本将确保快速崛起的中国城市在未来持续获得成功。 | Mike Hales Andres Mendoza Pena Erik Peterson Nicole Dessibourg-Freer 王宇 周鹏远 | 2019 | 科技中国2019，，7： | 4 |
| 8 | Mycobacterium avium subspecies paratuberculosis and its relationship with Crohn's disease显示文摘The hypothesis postulating that Mycobacterium avium paratuberculosis(MAP) is the cause of Crohn's disease(CD) has been circulating for many years.Advances in molecular techniques,such as polymerase chain reaction and culture methods,have enabled researchers to demonstrate that there is an association between MAP and CD.Recently,genome-wide association studies have identified novel susceptibility genes for CD,which are critical for generation of an adaptive immune response that is protective against intracellular pathogens,including M.tuberculosis infection.However,the role of MAP as a cause of CD suffered a setback with the report that administration of antimycobacterial therapy failed to lead to a sustained response in CD patients.Accordingly,this review sought neither to confirm nor refute this,but instead to survey recent literature on the role of MAP in CD. | Juan Luis Mendoza Raquel Lana Manuel Díaz-Rubio | 2009 | World Journal of Gastroenterology2009，15，4： | 4 |
| 9 | IBD5 polymorphisms in inflammatory bowel disease: Association with response to infliximab显示文摘AIM: Inflammatory bowel diseases (IBD) are multifactorial pathologies of unknown etiology. One susceptibility locus,IBD5, has been mapped to chromosome 5q31. We analyzed our Spanish cohorts of Crohn's disease (CD)and ulcerative colitis (UC) patients to determine whether this locus is associated with IBD, and to ascertain the main clinical phenotype influenced by this risk factor. The kind of interaction, either genetic heterogeneity or epistasis, between this IBD5 susceptibility region and the NOD2/CARD15 gene mutations was studied as well.Finally, ve assessed whether this locus can predict response to infliximab therapy.METHODS: A case control study was performed with 274CD and 211 UC patients recruited from a single center and 511 healthy ethnically matched controls. Two polymorphisms were genotyped in the IBD5 locus and three in the CARD15/NOD2 gene.RESULTS: Our results evidence association only with CD especially with the fistulizing phenotype and in the absence of NOD2/CARD15 variants (mutant allele frequency in patients vscontrols: OR = 2.03, 95% CI = 1.35-3.06,P<0.01). The frequency of the IBD5 homozygous mutant genotype significantly increased in CD patients lacking response to infliximab (RR = 3.88, 95% CI = 1.18-12.0,P<0.05). UC patients overall do not show association with 5q31 polymorphisms, although a similar trend to the one observed in CD is found within the worse prognosis group.CONCLUSION: The IBD5 variants may enhance an individual carrier's risk for CD, mainly in the absence of the NOD2/CARD15 mutations and in fistulizing patients.The data presented suggest the potential role of the 5q31polymorphisms as markers of response to infiiximab. | Elena Urcelay Juan Luis Mendoza Alfonso Martínez Laura Fernández Carlos Taxonera Manuel Díaz-Rubio Emilio G.de la Concha | 2005 | World Journal of Gastroenterology2005，11，8： | 4 |
| 10 | Antiviral activity of maca ( Lepidium meyenii ) against human influenza virus显示文摘 | Juana del Valle Mendoza Tomàs Pumarola Libertad Alzamora Gonzales Luis J. del Valle | 2014 | Asian Pacific Journal of Tropical Medicine2014，，： | 3 |
| 11 | Pig Manure Systems in Germany and China and the Impact on Nutrient Flow显示文摘 | F. Schuchardtl, T. Jiang T. Jiang G. X. Li R. Mendoza Huaitalla | 2011 | Journal of Agricultural Science and Technology(A)2011，1，6： | 3 |
| 12 | Methylation of DAPK and THBS1 genes in esophageal gastric-type columnar metaplasia显示文摘AIM: To explore methylation of DAPK, THBS1, CDH-1, and p14 genes, and Helicobacter pylori(H. pylori) status in individuals harboring esophageal columnar metaplasia.METHODS: Distal esophageal mucosal samples obtained by endoscopy and histologically diagnosed as gastric-type(non-specialized) columnar metaplasia, were studied thoroughly. DNA was extracted from paraffin blocks, and methylation status of deathassociated protein kinase(DAPK), thrombospondin-1(THBS1), cadherin-1(CDH1), and p14 genes, was examined using a methyl-sensitive polymerase chain reaction(MS-PCR) and sodium bisulfite modification protocol. H. pylori cag A status was determined by PCR.RESULTS: In total, 68 subjects(33 females and 35 males), with a mean age of 52 years, were included. H. pylori cag A positive was present in the esophageal gastric-type metaplastic mucosa of 18 individuals. DAPK, THSB1, CDH1, and p14 gene promoters were methylated by MS-PCR in 40(58.8%), 33(48.5%), 46(67.6%), and 23(33.8%) cases of the 68 esophageal samples. H. pyloristatus was associated with methylation of DAPK(P = 0.003) and THBS1(P = 0.019).CONCLUSION: DNA methylation occurs in cases of gastric-type(non-specialized) columnar metaplasia of the esophagus, and this modification is associated with H. pylori cag A positive infection. | Roberto Herrera-Goepfert Luis F Onate-Ocana José Luis Mosqueda-Vargas Luis A Herrera Clementina Castro Julia Mendoza Rodrigo González-Barrios | 2016 | World Journal of Gastroenterology2016，22，18： | 3 |
| 13 | Long-term outcome of chronic hepatitis C patients with sustained virological response to peginterferon plus ribavirin显示文摘AIM: To assess the clinical, biochemical and virological long-term outcome in chronic hepatitis C (CHC) patients with a sustained virological response (SVR) after peginterferon (PEG-IFN) plus ribavirin combination therapy. METHODS: One hundred and fifty three patients with a SVR after treatment with PEG-IFN plus ribavirin were included in a 5-year follow-up study in a single Spanish center, based on standard clinical practice. Clinical anamnesis, biochemical analysis, hepatitis C virus RNA and alpha-fetoprotein measurement, ultrasonography and transient elastography were performed annually. RESULTS: The mean follow-up period of the 153 patients was 76 ± 13 mo after they obtained a SVR. Five patients (3.26%) presented with cirrhosis before treatment and 116 (75.8%) had genotype 1. No patient showed evidence of hepatic decompensation. One patient (0.65%) developed a hepatocellular carcinoma at month 30 after achieving SVR. There were no virological relapses during this follow-up period. Persistently elevated alanine aminotransferase was found in only one patient (0.65%). At the end of the 5-year follow-up, the mean value of transient elastography was 7 ± 4.3 kPa (F1). There were no deaths and no other tumors. CONCLUSION: The long-term outcome of 153 CHC patients with SVR to PEG-IFN plus ribavirin was good. No evidence of a virological relapse was seen. One patient (0.65%) developed a hepatocellular carcinoma. | María Trapero-Marugán Jorge Mendoza María Chaparro Leticia González-Moreno José Andrés Moreno-Monteagudo María Jesús Borque Ricardo Moreno-Otero | 2011 | World Journal of Gastroenterology2011，17，4： | 3 |
| 14 | Empirical evaluation of confidence and prediction intervals for spatial models of forest structure in Jalisco,Mexico显示文摘In recent years there has been an increasing interest in developing spatial statistical models for data sets that are seemingly spatially independent.This lack of spatial structure makes it difficult,if not impossible to use optimal predictors such as ordinary kriging for modeling the spatial variability in the data.In many instances,the data still contain a wealth of information that could be used to gain flexibility and precision in estimation.In this paper we propose using a combination of regression analysis to describe the large-scale spatial variability in a set of survey data and a tree-based stratification design to enhance the estimation process of the small-scale spatial variability.With this approach,sample units(i.e.,pixel of a satellite image) are classified with respect to predictions of error attributes into homogeneous classes,and the classes are then used as strata in the stratified analysis.Independent variables used as a basis of stratification included terrain data and satellite imagery.A decision rule was used to identify a tree size that minimized the error in estimating the variance of the mean response and prediction uncertainties at new spatial locations.This approach was applied to a set of n=937 forested plots from a state-wide inventory conducted in 2006 in the Mexican State of Jalisco.The final models accounted for 62% to 82% of the variability observed in canopy closure(%),basal area(m2·ha-1),cubic volumes(m3·ha-1) and biomass(t·ha-1) on the sample plots.The spatial models provided unbiased estimates and when averaged over all sample units in the population,estimates of forest structure were very close to those obtained using classical estimates based on the sampling strategy used in the state-wide inventory.The spatial models also provided unbiased estimates of model variances leading to confidence and prediction coverage rates close to the 0.95 nominal rate. | Robin M.Reich C.Aguirre-Bravo Vanessa A.Bravo Martin Mendoza Briseo | 2011 | Journal of Forestry Research2011，22，2： | 3 |
| 15 | The effect of Saccharomyces cerevisiae on digestion and mortality in the volcano rabbit(Romerolagus diazi)显示文摘An experiment was conducted to evaluate whether supplementation with a probiotic could enhance digestion and reduce mortality in the volcano rabbit in captivity. Two enclosures at Chapultepec Zoo, Mexico(114 individuals) were used in a crossover design(two periods of 60 days) with the following treatments: control group and supplementation with Saccharomyces cerevisiae(2×108 CFU/exhibit/day). Supplementation with the probiotic negatively affected(P<0.01) the digestibility of dry matter, organic matter, neutral detergent fiber(NDF) and energy. Mortality increased(P<0.04) following supplementation with the probiotic(4.26% vs. 8.89%), primarily in the juvenile rabbits. The results indicate that yeast supplementation in the volcano rabbit negatively affects digestion and mortality in captivity. | Rogelio Campos-Morales Germán D Mendoza Javier Ojeda Fernando X Plata José A Martínez | 2015 | Journal of Integrative Agriculture2015，14，3： | 2 |
| 16 | Need for infliximab dose intensification in Crohn's disease and ulcerative colitis显示文摘AIM: To compare the need for infliximab dose intensification in two cohorts of patients with Crohn's disease(CD) or ulcerative colitis(UC).METHODS: Single centre, uncontrolled, observational study. Consecutive patients with CD and UC who responded to infliximab induction doses were included. Data collected in a prospectively maintained database were retrospectively analysed. Differences in the rates of dose intensification per patient-month and the intensification-free survival time were compared. We also evaluated the interval between the first infliximab induction dose and the first infliximab escalated dose. The weight-adjusted infliximab administration costs were also calculated.RESULTS: Fifty nine patients with CD and 38 patients with UC were enrolled. The rate of intensification per patient-month was 3.9% for UC and 1.4% for CD(P = 0.005). The median time from baseline to intensification was significantly shorter in UC compared to CD [6.6 mo(IQR: 4.2-9.5 mo) vs 10.7 mo(IQR: 8.9-11.7 mo), P = 0.005]. In the survival analysis, the cumulative probability of avoiding infliximab dose intensification was significantly higher in CD(P = 0.002). In the multivariate analysis, disease(UC vs CD) was the only factor significantly associated with dose intensification. The infiximab administration costs during the first year were significantly higher for UC compared to CD(mean ± SD 234.9 ± 53.3 Euros/kg vs 212.3 ± 15.1 Euros/kg, P = 0.03).CONCLUSION: The rate of infliximab dose intensification per patient-month is significantly higher in UC patients. The infliximab administration costs are also significantly higher in patients with UC. | Carlos Taxonera David Olivares Juan L Mendoza Manuel Díaz-Rubio Enrique Rey | 2014 | World Journal of Gastroenterology2014，20，27： | 2 |
| 17 | Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?显示文摘Glucose-6-phosphate dehydrogenase(G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage prevention.Erythrocytes have a predisposition towards oxidized environments due to their lack of mitochondria,giving G6 PD a major role in its stability.G6 PD deficiency(G6PDd) is the most common enzyme deficiency in humans:it affects approximately 400 million individuals worldwide.The overall G6 PDd allele frequency across malaria endemic countries is estimated to be 8%.corresponding to approximately 220 million males and 133 million females.However,there are no reports on the prevalence of G6 PDd in Andean communities where bartonellosis is prevalent. | Fernando Mazulis Claudia Weilg Carlos Alva-Urcia Maria J.Pons Juana del Valle Mendoza | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，12： | 2 |
| 18 | Sphincter of oddi manometry in healthy volunteers显示文摘 | Dr. Moises Guelrud MD FACG Sonia Mendoza MD Guillermo Rossiter MD Maria I. Villegas MD | 1990 | Digestive Diseases and Sciences1990，，1： | 2 |
| 19 | Aerial pollutants on a pig farm in peri-urban Beijing,China显示文摘The study was carried out to evaluate the airborne gases and suspended particulate matter concentrations in the pig barns of a commercial pig farm situated in the peri-urban area of Beijing,China.The measurements followed the natural pig life-stages namely:gestation,farrowing,weaning,and fattening.In order to accomplish these objectives,three different measurement devices were employed:(i)color diffusion tubes,(ii)a portable gas measuring device,and(iii)a dust measuring instrument.Due to the rotation of the devices in the different sampling places,the measurements were performed at different time periods during the months of the summer and winter season in Beijing.The pig farm had a capacity of 15000 pigs per year and the manurial system was identified as“gan qing fen”or dry cleaning of the manure.The main by-products generated by the farm were irrigation water and small-scale biogas production.High dust concentrations were identified in the pig barns,especially during the feeding and manure cleaning events inside the farrowing and weaning barns with slatted floors.Inhalable dust ranged from 0 mg/m3 to 12.45 mg/m3,while the allowable dust ranged from 0 mg/m3 to 9.62 mg/m3.Ammonia concentration ranged from 0 ppm to 20 ppm(1 ppm=1 cm3/m3),and the carbon dioxide concentration ranged from 300 ppm to 8000 ppm.The highest ammonia concentration was recorded in the fattening barn during the summer season,while the highest carbon dioxide concentration was reported in the weaning barn during the summer season.The results of this study were similar to the results of studies performed on pig farms under natural and mechanical ventilation systems.On the other hand,the problems encountered during the gas measurements on the pig farm were directly related to the inadequate housing layout due to the obstruction of windows,fans and air channels for indoor ventilation,and thus the measurement devices faced harsh working conditions.Therefore,it is recommended that the housing system should be improved with repaired windows and curtains especially for the winter season;similarly,the repair of the fans should be attempted in order to improve the ventilation,especially in the gestation barns. | Roxana Mendoza Huaitalla Eva Gallmann Liu Xuejun Eberhard Hartung | 2013 | International Journal of Agricultural and Biological Engineering2013，6，1： | 2 |
| 20 | Problems in the Management of Type III (Severe) Open Fractures: A New Classification of Type III Open Fractures显示文摘 | RAMON B. GUSTILO REX M. MENDOZA DAVID N. WILLIAMS | 1984 | The Journal of Trauma: Injury, Infection, and Critical Care1984，，： | 2 |
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