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82篇 您的检索式:作者名="MARRUGAT J"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Body iron stores and early neurologic deterioration in acute cerebral infarction显示文摘Davalos A Castillo J Marrugat J 2000Neurology2000,54,8:1
3Body iron stores and early neuro- logic deterioration in acute cerebral infarction显示文摘Davalos A Castillo J Marrugat J 2000Neurology2000,54,8:1
4Timing for fever-related brain damage in acute ischemic stroke 显示文摘CASTILLO J DAVALOS A MARRUGAT J 1998Stroke1998,29,12:1
5Risk functions and the primary prevention of cardiovascular disease显示文摘Grau M Marrugat J 2008Rev Esp Cardiol2008,61,4:1
6Alcohol consumption is directly associated with circulating oxidized low- density lipoprotein显示文摘SCHRODER H MARRUGAT J FITO M 2006Free Radic Biol Med2006,40,8:1
7Body iron stores and early neurologic deterioration in acute cerebral infarction显示文摘Davalos A Castillo J Marrugat J 2000Neurology2000,54,8:1
8Coronary risk estimation in Spain using a calibrated Framingham function显示文摘Marrugat J Solanas P D Agostino R 2003Rev Esp Cardiol2003,56,3:1
9Timing for fever-related brain damage in acute ischemic st roke显示文摘Castillo J Dávalos A Marrugat J 1998Stroke1998,29,12:1
10Age at onset of smoking is an independent risk factor in peripheral artery disease development显示文摘Planas A Clará A Marrugat J 2002J Vasc Surg2002,35,3:1
11Validity of an adaptation of the Framingham cardiovascular risk function:the VERIFICA study显示文摘Marrugat J Subirana I Comin E 0,,:1
12Amount and intensity of physical activ- ity, physical fitness, and serum lipids in men显示文摘Marrugat J Elosua R Covas MI 1996Am J Epidemlol1996,143,:1
13Timing for fever-related brain damage in acute ischemic stroke显示文摘Castillo J Davalos A Marrugat J et at 1998Stroke1998,29,:1
14An adaptation of the Framingham coronary heart disease risk function to European Mediterranean areas显示文摘 D'Agostino R Sullivan L 2003J Epidemiol Community Health2003,57,:1
15Long-term en- durance sport practice increases the incidence of lone atrial fi- brillation in men: A follow-up study显示文摘MOLINA L MONT L MARRUGAT J 2008Europace2008,10,5:1
16High monetary costs of dietary patterns associated with lower body mass index: a population- based study 显示文摘SCHRODER H MARRUGAT J COVAS M I 2006Inter J Obese2006,30,:1
17Decrease of skin and bronchial sensitization following short-intensive scheduled immunotherapy in mite allergic asthma显示文摘Garcia-Ortega P Merelo A Marrugat J 1993Chest1993,103,:1
18Long-term endurance sport practice in- creases the incidence of lone atrial fibrillation in men : a follow-up study 显示文摘Molina L Mont L Marrugat J 2008Europace2008,10,:1
19Coronary risk estimation in Spain using a calibrated Framingham function 显示文摘Marrugat J Solanas P D'Agostino R 2003Rev Esp Cardiol2003,56,3:1
20Timing for fever-relatedbrain damage in acute ischemic stroke显示文摘Castillo J Davalos A Marrugat J 1998Stroke1998,29,1:1
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