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| 1 | CIC-3 chloride channels are essential for cell proliferation and cell cycle progression in nasopharyngeal carcinoma cells显示文摘ClC-3,为激活卷的氯化物编码候选人蛋白质的基因(Cl ?) 隧道,可以涉及肿瘤开发。此处,我们用 antisense 报导研究调查 ClC-3 在鼻咽的癌 CNE-2Z 房间由影响房间增长的机制的击倒的策略。与 immunoblots 和 MTT 试金,我们证明 ClC-3 的表示是房间周期依赖者并且以一种类似的集中依赖者方式,为 ClC-3 特定的 antisense oligonucleotide 禁止了 ClC-3 蛋白质表示和房间增长。ClC-3 的表示水平与房间增长相关。而且在暴露于 ClC-3 antisense oligonucleotide 的房间,克隆的效率被禁止,并且房间在 S 阶段被逮捕。ClC-3 antisense oligonucleotide 禁止了激活卷的 Cl 吗?当前(ICl,体积) 并且以一种集中依赖者方式的规章的体积减少(RVD ) 。另外, ICl,体积或 RVD 断然在对待的房间与房间增长被相关。在结论, ClC-3 通过包含 ICl,体积和 RVD 的调整的机制涉及房间增长和房间周期前进。CIC-3 可以在人的癌症代表一个治疗学的目标。 | Bin Xu Jianwen Mao Liwei Wang Linyan Zhu Hongzhi Li Weizhang Wang Xiaobao Jin Jiayong Zhu Lixin Chen | 2010 | Acta Biochimica et Biophysica Sinica2010，42，6： | 12 |
| 2 | Development of an Amphibious Turtle-Inspired Spherical Mother Robot显示文摘 | Liwei Shi Shuxiang Guo Shilian Mao Chunfeng Yue Maoxun Li Kinji Asaka | 2013 | Journal of Bionic Engineering2013，10，4： | 7 |
| 3 | Stable Lithium-Carbon Composite Enabled by Dual-Salt Additives显示文摘Lithium metal is regarded as the ultimate negative electrode material for secondary batteries due to its high energy density.However,it suffers from poor cycling stability because of its high reactivity with liquid electrolytes.Therefore,continuous efforts have been put into improving the cycling Coulombic efficiency(CE)to extend the lifespan of the lithium metal negative electrode.Herein,we report that using dual-salt additives of LiPF_(6) and LiNO_(3) in an ether solvent-based electrolyte can significantly improve the cycling stability and rate capability of a Li-carbon(Li-CNT)composite.As a result,an average cycling CE as high as 99.30% was obtained for the Li-CNT at a current density of 2.5 mA cm^(-2) and an negative electrode to positive electrode capacity(N/P)ratio of 2.The cycling stability and rate capability enhancement of the Li-CNT negative electrode could be attributed to the formation of a better solid electrolyte interphase layer that contains both inorganic components and organic polyether.The former component mainly originates from the decomposition of the LiNO_(3) additive,while the latter comes from the LiPF_(6)-induced ring-opening polymerization of the ether solvent.This novel surface chemistry significantly improves the CE of Li negative electrode,revealing its importance for the practical application of lithium metal batteries. | Lei Zheng Feng Guo Tuo Kang Yingzhu Fan Wei Gu Yayun Mao Ya Liu Rong Huang Zhiyun Li Yanbin Shen Wei Lu Liwei Chen | 2021 | Nano-Micro Letters2021，13，7： | 3 |
| 4 | Impact of Land Use Change on Vegetation Carbon Storage During Rapid Urbanization:A Case Study of Hangzhou,China显示文摘Land use changes have significant impacts on the carbon balance in an urban ecosystem.When there is rapid development in urbanizing regions,land use changes have a dramatic effect on vegetation carbon storage(VCS).This study investigates the impact of land use change on VCS in a period of rapid urbanization in Hangzhou,China.The results show that:1)from 2000 to 2015,land use in Hangzhou underwent huge changes,mainly reflected in decrease in cropland and wetland and the increased settlement.More than 34.58%of the land was transformed,and the land use changes are primarily characterized by a significant decrease in cropland due to the occupation by settlement.2)over the 15 years,changes in land use led to a decrease of 3.93×10^(5) t of VCS in the urban ecosystem.The large-scale transformation of cropland and wetland,which have a comparatively high carbon density,into land for settlement exerted a negative impact on VCS.3)The central city,which with the Circle-E/I/O mode,had the lowest comprehensive land use dynamic degree,leading to moderate land use change and an increase in VCS;Yuhang and Xiaoshan,which with Multicore-E/O/I mode and Fan-E/O/I modes,had a higher comprehensive land use dynamic degree,drastic changes in land use,and a decrease in VCS.This study proposes a reliable method of estimating changes in VCS,clarifies the relationship between land use change and VCS during rapid urbanization,and provides recommendations for sustainable urban development. | WANG Zhi XU Lihua SHI Yijun MA Qiwei WU Yaqi LU Zhangwei MAO Liwei PANG Enqi ZHANG Qi | 2021 | Chinese Geographical Science2021，31，2： | 3 |
| 5 | Characterization of DNA damage response deficiency in pancreatic cancer patients from China显示文摘To the editor,Pancreatic ductal adenocarcinoma(PDAC)has the worst prognosis among all common malignant solid tumors,with a 5-year overall survival(OS)rate of less than 10%[1].Few effective targets for anticancer ther-apy have been confirmed in pancreatic cancer.Recently,it was substantiated that pancreatic cancer patients carry-ing deleterious mutations of the DNA damage response(DDR)genes are more likely to benefit from platinum-based chemotherapy[2]and poly(adenosine diphosphate-ribose)polymerase(PARP)inhibitor[3]. | Xiaofei Zhang Tiebo Mao Bei Zhang Haiyan Xu Jiujie Cui Feng Jiao Dongqin Chen Yu Wang Jiong Hu Qing Xia Shumin Li Ming Yue Jingyu Ma Jiayu Yao Yongchao Wang Xiao Zhang Shiqing Chen Yuezong Bai Yuexiang Wang Xuebin Zhang Qiang Liu Yongwei Sun Deliang Fu Yingbin Liu Lei Xiong Liwei Wang | 2022 | Cancer Communications2022，42，1： | 2 |
| 6 | Trimethoxyboroxine as an electrolyte additive to enhance the 4.5V cycling performance of a Ni-rich layered oxide cathode显示文摘Ni-rich layered oxides are attractive cathode materials for advanced lithium-ion batteries(LIBs)due to their high energy density.However,their large-scale application is seriously hindered by their interfacial instability,especially at a high cut-off potential.Here,we demonstrate that trimethoxyboroxine(TMOBX)is an effective film-forming additive to address the interfacial instability of LiNi0.8Co0.1Mn0.1O_(2)(NCM811)material at a high cut-off voltage of 4.5V.We find that TMOBX decomposes before carbonate solvent and forms a thin cathode electrolyte interphase(CEI)layer on the surface of the NCM811 material.This TMOBX-formed CEI significantly suppresses electrolyte decomposition at a high potential and inhibits the dissolution of transition metals from NCM811 during cycling.In addition,electron-deficient borate compounds coordinate with anions(PF6^(−),F^(-) etc.)and H2O in the battery,further improving the battery's stability.As a result,adding 1.0wt%of TMOBX boosts the capacity retention of a Li||NCM811cell from 68.72%to 86.60%after 200 cycles at 0.5C in the range of 2.8–4.5V. | Wei Gu Guoyong Xue Qingyu Dong Ruowei Yi Yayun Mao Lei Zheng Haikuo Zhang Xiulin Fan Yanbin Shen Liwei Chen | 2022 | eScience2022，2，5： | 1 |
| 7 | Densely packed overlayer of iron phthalocyanine molecules grown on single-layer graphene显示文摘The formation of densely packed overlayer of iron phthalocyanine(FePc) molecules on single-layer graphene(SLG) epitaxially grown on Ru(0001) is studied by means of low temperature scanning tunneling microscopy. We show that the FePc molecules form single molecular arrays, ordered honeycomb lattice, Kagome lattice and square lattice with increasing molecular coverage. The densely packed square lattice of the molecular layer is modulated by the moire pattern of SLG/Ru(0001). The superposition of the square lattice of the molecular layer on the hexagonal lattice of SLG moire pattern leads to the formation of a larger strip moiré pattern. This coverage-dependent self-assembling behavior of FePc on SLG/Ru(0001) is mainly driven by the inhomogeneous electronic structure of graphene moire pattern, due to spatial-dependent interfacial charge transfer between SLG and Ru(0001) substrate. | Liwei Liu Wende Xiao Jinhai Mao Haigang Zhang YuhangJiang Haitao Zhou Kai Yang Hongjun Gao | 2018 | Chinese Chemical Letters2018，29，1： | 0 |
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