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| 1 | Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis显示文摘像域的蛋白质(Mlkl ) 最近被发现与受体交往交往的混合的系 kinase 蛋白质 3 (Rip3 ) 并且导致的坏死因素(TNF ) 在有教养的房间线规划了坏死(necroptosis ) 为肿瘤必要。我们由抄写产生了 Mlkl 缺乏的老鼠像使活跃之物的受动器核酸酶(TALEN ) 调停了基因混乱和发现 Mlkl 到为象有免疫力的房间开发一样的正常老鼠开发非必需。胚胎的成纤维细胞(MEF ) 和巨噬细胞两个都显示出的 Mlkl 缺乏的老鼠抵抗到坏死然而并非 apoptotic 刺激。Mlkl 缺乏的 MEF 和巨噬细胞与处于他们激活 NF-κ 的能力的野类型的房间难区分;响应 TNF 和 lipopolysaccharides (LPS ) 的 B,英皇家空军之阶级最低之兵, JNK,和 p38 分别地。一致地, Mlkl 缺乏的巨噬细胞和老鼠展出了正常 interleukin-1β(IL-1β) ,在 LPS 处理以后的 IL-6,和 TNF 生产。Mlkl 缺乏保护老鼠免受导致天蓝色的尖锐胰腺炎的伤害,坏死相关的疾病,但是没在 polymicrobial 上有效果腐败导致吃惊的动物死亡。我们的结果在 necroptosis 为 Mlkl 的角色提供基因证据。 | Jianfeng Wu Zhe Huang Junming Ren Zhirong Zhang Peng He Yangxin Li Jianhui Ma Wanze Chen Yingying Zhang Xiaojuan Zhou Zhentao Yang Su-Qin Wu Lanfen Chen Jiahuai Han | 2013 | Cell Research2013，23，8： | 35 |
| 2 | Facile Synthesis and Application of Ag-Chemically Converted Graphene Nanocomposite显示文摘An in situ chemical synthesis approach has been employed to prepare an Ag-chemically converted graphene (CCG) nanocomposite. The reduction of graphene oxide sheets was accompanied by generation of Ag nanoparticles. The structure and composition of the nanocomposites were confirmed by means of transmission electron microscopy (TEM), atomic force microscopy (AFM) and X-ray diffraction. TEM and AFM results suggest a homogeneous distribution of Ag nanoparticles (5-10 nm in size) on CCG sheets. The intensities of the Raman signals of CCG in such nanocomposites are greatly increased by the attached silver nanoparticles, i.e., there is surface-enhanced Raman scattering activity. In addition, it was found that the antibacterial activity of free Ag nanoparticles is retained in the nanocomposites, which suggests they can be used as graphene-based biomaterials. | Jianfeng Shen Min Shi Na Li Bo Yan Hongwei Ma Yizhe Hu Mingxin Ye | 2010 | Nano Research2010，3，5： | 29 |
| 3 | Lightweight Design and Verification of Gantry Machining Center Crossbeam Based on Structural Bionics显示文摘 | Ling Zhao Jianfeng Ma Wuyi Chen Hongliang Guo | 2011 | Journal of Bionic Engineering2011，8，2： | 22 |
| 4 | Glucocorticoid receptor and sequential P53 activation by dexamethasone mediates apoptosis and cell cycle arrest of osteoblastic MC3T3-E1 cells显示文摘 | Li Hui Yao Jianfeng Liu Hui Liu Shuguang Xu Peng Ma Jianbing Zhang Yumin | 2012 | 美中国际创伤杂志2012，11，1： | 22 |
| 5 | Ionic Liquid-Assisted One-Step Hydrothermal Synthesis of TiO2-Reduced Graphene Oxide Composites显示文摘我们为可溶的减少的 graphene 氧化物表(RGO ) 和钛氧化物(TiO2 ) 的准备的制造表明了灵巧、有效的策略用一出修改一步舞的 nanoparticle-RGO composites 热水的方法。graphene 氧化物能容易作为 reductant 与维生素酸在 solvothermal 条件下面被减少,这被发现,与 RGO 表面上的 TiO2 粒子的伴随物生长。TiO2-RGO 合成被 Fourier 变换彻底地描绘了红外线的光谱学,拉曼光谱学, X 光检查衍射, X 光检查光电子光谱学,和 thermogravimetric 分析。显微镜学技术(扫描电子显微镜学,原子力量显微镜学,和传播电子显微镜学) 被采用了探查词法特征以及调查 RGO 表的脱落。TiO2-RGO 氢的合成展出优秀光催化进化。 | Jianfeng Shen Min Shi Bo Yan Hongwei Ma Na Li Mingxin Ye | 2011 | Nano Research2011，4，8： | 18 |
| 6 | Identity-based public auditing for cloud storage systems against malicious auditors via blockchain显示文摘Cloud storage systems provide users with convenient data storage services, which allow users to access and update outsourced data remotely. However, these cloud storage services do not guarantee the integrity of the data that users store in the cloud. Thus, public auditing is necessary, in which a third-party auditor(TPA) is delegated to audit the integrity of the outsourced data. This system allows users to enjoy on-demand cloud storage services without the burden of continually auditing their data integrity. However,certain TPAs might deviate from the public auditing protocol and/or collude with the cloud servers. In this article, we propose an identity-based public auditing(IBPA) scheme for cloud storage systems. In IBPA,the nonces in a blockchain are employed to construct unpredictable and easily verified challenge messages,thereby preventing the forging of auditing results by malicious TPAs to deceive users. Users need only to verify the TPAs' auditing results in batches to ensure the integrity of their data that are stored in the cloud.A detailed security analysis shows that IBPA can preserve data integrity against various attacks. In addition,a comprehensive performance evaluation demonstrates that IBPA is feasible and efficient. | Jingting XUE Chunxiang XU Jining ZHAO Jianfeng MA | 2019 | Science China(Information Sciences)2019，62，3： | 17 |
| 7 | Survey on cyberspace security显示文摘Along with the rapid development and wide application of information technology, human society has entered the information era. In this era, people live and work in cyberspace. Cyberspace is the collection of all information systems; it is the information environment for human survival. Therefore, it is necessary to ensure the security of cyberspace. This paper gives a comprehensive introduction to research and development in this field, with a description of existing problems and some currently active research topics in the areas of cyberspace itself, cyberspace security, cryptography, network security, information system security and information content security. | ZHANG HuanGuo HAN WenBao LAI XueJia LIN DongDai MA JianFeng LI JianHua | 2015 | Science China(Information Sciences)2015，58，11： | 15 |
| 8 | Mars Express tracking and orbit determination trials with Chinese VLBI network显示文摘With strong support from European Space Agency (ESA),Shanghai Astronomical Observatory (SHAO) organized a tracking and orbit determination trails using Chinese VLBI Network (CVN) to track Mars Express,the first Mars probe launched by ESA. Using a high-resolution VLBI software correlator and Doppler measurement system developed in-house,two sets of tracking data,VLBI and Doppler,were acquired. The trials represent the first successful foray held in China to track a probe about 360 million kilometers away from the Earth. The tracking data are analyzed using a Mars satellite orbit determination software system developed at SHAO. The results show that the accuracy of 5 s integrated three-way-Doppler data is about 0.3 mm/s,or roughly the same accuracy as ESA's tracking data. Position discrepancies between the Doppler-based orbit solution of 8 h arc-length (about 1 orbital revolution) and ESA's reconstructed orbit are of the order of several hundred meters. In preparing for the Russia-China co-sponsored Mars exploration mission Phobos-Grunt-YingHuo,simulations were carried out to evaluate the achievable orbital accuracy levels and the contributions of VLBI and Doppler data respectively. Results show that Doppler data provide better orbit accuracy,so that for VLBI to be able to provide kilometer level orbit solutions,the accuracy of VLBI measurement needs to be improved by at least one order of magnitude. | CAO JianFeng HUANG Yong HU XiaoGong MA maoLi ZHENG WeiMin | 2010 | Chinese Science Bulletin2010，55，32： | 14 |
| 9 | Association of KIR Genotypes and Haplotypes with Susceptibility to Chronic Hepatitis B Virus Infection in Chinese Han Population显示文摘Killer immunoglobulin-like receptor (KIR) genes can regulate the activation of NK and T cells upon interaction with HLA class I molecules. Hepatitis B virus (HBV) infection has been regarded as a multi-factorial disorder disease. Previous studies revealed that KIRs were involved in HCV and HIV infection or clearance. The aim of this study was to explore the possibility of the inheritance of KIR genotypes and haplotypes as a candidate for susceptibility to persistent HBV infection or HBV clearance. The sequence specific primer polymerase chain reaction (SSP-PCR) was employed to identify the KIR genes and pseudogenes in 150 chronic hepatitis B (CHB) patients, 251 spontaneously recovered (SR) controls, and 412 healthy controls. The frequencies of genotype G, M, FZ1 increased in CHB patients compared with healthy control subjects. The frequency of genotype AH was higher in SR controls than that in both CHB patients and healthy controls. The carriage frequencies of genotype G and AH were higher; while, the frequencies of AF and AJ were lower in SR controls than those in healthy control subjects. The frequency of A haplotype was lower, whereas, the frequency of B haplotype was higher in CHB patients and SR controls than those in healthy controls. In healthy controls, haplotype 4 was found lower compared with that in CHB patients and SR controls and the frequency of haplotype 5 was higher in SR controls than that in other two groups. Based on these findings, it seems that the genotypes M and FZ1 are HBV susceptive genotypes; AH, on the other hand, may be protective genotypes that facilitate the clearance of HBV. It appears that the haplotype 4 is HBV susceptive haplotype, whereas, haplotype 5 may be the protective haplotype that facilitates the clearance of HBV. | Zhiming Lu Bingchang Zhang Shijun Chen Zhongtao Gai Zhaolei Feng Xiangdong Liu Yiqing Liu Xin Wen Li Li Yulian Jiao Chunyan Ma Song Shao Xiangfa Cui Guojian Chen Jianfeng Li Yneran Zhao | 2008 | Cellular & Molecular Immunology2008，5，6： | 13 |
| 10 | Universally composable one-time signature and broadcast authentication显示文摘Broadcast authentication is a vital security primitive for the management of a copious number of parties. In the universally composable framework, this paper investigates broadcast authentication using one-time signature based on the fact that one-time signature has efficient signature generation and verification suitable for low-power devices, and gives immediate authentication, which is a favorable property for time-critical messages. This paper first formulates a broadcast authentication model with the ideal functionalities such as one-time signature and broadcast authentication, and proposes a broadcast authentication scheme in the hybrid model. This paper then improves HORS, which is secure based on a strong assumption (i.e., a subset-resilient hash function) and presents the improved version as HORS+, which diffiers from HORS such that it is a secure one-time signature based on weaker assumptions, i.e. one-way functions, one-way hash functions and collisionresistant hash functions. At the same time, a protocol OWC using one-way chains is proposed to provide more registered keys for multi-message broadcast authentication. Our broadcast authentication scheme constructed by the combined use of HORS+ and OWC is universally composable secure and suitable for low-power devices. | ZHANG JunWei MA JianFeng MOON SangJae | 2010 | Science China(Information Sciences)2010，53，3： | 12 |
| 11 | Geochemical Characteristics and Geological Significance of Early Permian Baya'ertuhushuo Gabbro in South Great Xing'an Range显示文摘领域地质的调查和 geochemical 分析在南方伟人 Xing'an 在 Baya'ertuhushuo 斑粝岩上被执行范围。当以前想了,领域调查表明斑粝岩是 magmatic 侵入而非一间 ophiolite 套房的一个部件。标明日期的诱导地联合的血浆团光谱学(LA-ICP-MS ) U-Pb 显示的锆石激光脱离斑粝岩在 274275 妈,被形成就作为 Dashizhai 形成(P1d ) 的普遍暴烈的岩石,在学习区域的 monzogranites 和 miarolitic 碱长石花岗石。斑粝岩有在 47.23 wt% 之间的 SiO2 内容,分别地, 50.17 wt% ,高 MgO 和 FeOT 6.9511.29 满足 wt% 和 7.3212.24 wt% ,它在 SiO2-K2O 图属于 low-K tholeiitic 系列。使球粒状陨石正常化的稀土元素元素(REE ) 模式和斑粝岩的原始使披风正常化的蜘蛛图除了大离子亲石元素元素(LILE ) 的丰富类似于正常海中央理兹暗岩(N-MORB ) 的那些,例如 Rb, Ba 和 K。在踪迹元素构造的歧视的图,样品主要也在 situ Lu-Hf 同位素的分析在 N-MORB 领域,和锆石里被阴谋显示斑粝岩从弄空的披风发源。通过 geochemical 特征的合成研究和 Baya'ertuhushuo 斑粝岩的 petrogenesis ,在区域的 Dashizhai 形成和 granitoids 的暴烈的岩石,在 Xilinhot-Xiwuqi 区域的早二叠的 magmatism 在岩流圈 upwelling 的构造背景形成了,这被建议,它被 subducted 的打破离开引起Paleo亚洲的海洋平板。 | LIU Jianfeng CHI Xiaoguo ZHAO Zhi ZHANG Xingzhou MA Zhihong WANG Tiefu HU Zhaochu | 2011 | Acta Geologica Sinica(English Edition)2011，85，1： | 12 |
| 12 | A RISK ASSESSMENT METHOD OF THE WIRELESS NETWORK SECURITY显示文摘The core of network security is the risk assessment. In this letter,a risk assessment method is introduced to estimate the wireless network security. The method,which combines Analytic Hier-archy Process (AHP) method and fuzzy logical method,is applied to the risk assessment. Fuzzy logical method is applied to judge the important degree of each factor in the aspects of the probability,the influence and the uncontrollability,not to directly judge the important degree itself. The risk as-sessment is carved up 3 layers applying AHP method,the sort weight of the third layer is calculated by fuzzy logical method. Finally,the important degree is calculated by AHP method. By comparing the important degree of each factor,the risk which can be controlled by taking measures is known. The study of the case shows that the method can be easily used to the risk assessment of the wireless network security and its results conform to the actual situation. | Zhao Dongmei Wang Changguang Ma Jianfeng | 2007 | Journal of Electronics(China)2007，24，3： | 11 |
| 13 | Universally composable secure TNC model and EAP-TNC protocol in IF-T显示文摘This paper analyzes trusted network connect (TNC) protocols within the universally composable (UC) framework. We propose the first TNC model in the UC framework by first designing the TNC ideal functionality FTNC, the EAP ideal functionality FEAP and the EAP-TNC ideal functionality FE-PA. Then, we construct a trusted network connect protocol named TK-TNC that UC-realizes FTNC in the (FEAP, FE-PA)- hybrid model. Subsequently, we perform a security analysis on protocol D-H PN given in the TCG specification and show that this protocol cannot securely realize the EAP-TNC ideal functionality and be resistant to an attack. Finally, we propose an alternative protocol using the twin Diffie-Hellman key-exchange technique, named protocol TD-H PN, which can securely realize the EAP-TNC ideal functionality in the (FREG, FCERT)-hybrid model. | ZHANG JunWei MA JianFeng MOON SangJae | 2010 | Science China(Information Sciences)2010，53，3： | 11 |
| 14 | Efficient large-universe multi-authority ciphertext-policy attribute-based encryption with white-box traceability显示文摘Traceable multi-authority ciphertext-policy attribute-based encryption(CP-ABE) is a practical encryption method that can achieve user traceability and fine-grained access control simultaneously. However, existing traceable multi-authority CP-ABE schemes have two main limitations that prevent them from practical applications. First, these schemes only support small universe: the attributes must be fixed at system setup and the attribute space is restricted to polynomial size. Second, the schemes are either less expressive(the access policy is limited to 'AND gates with wildcard') or inefficient(the system is constructed in composite order bilinear groups). To address these limitations, we present a traceable large universe multi-authority CP-ABE scheme, and further prove that it is statically secure in the random oracle model.Compared with existing traceable multi-authority CP-ABE schemes, the proposed scheme has four advantages. First, the attributes are not fixed at setup and the attribute universe is not bounded to polynomial size. Second, the ciphertext polices can be expressed as any monotone access structures. Third, the proposed scheme is constructed in prime order groups, which makes this scheme more efficient than those in composite order bilinear groups. Finally, the proposed scheme requires neither a central authority nor an identity table for tracing. | Kai ZHANG Hui LI Jianfeng MA Ximeng LIU | 2018 | Science China(Information Sciences)2018，61，3： | 10 |
| 15 | Bayesian mechanism for rational secret sharing scheme显示文摘We consider the cooperation of rational parties in secret sharing. We present a new methodology for rational secret sharing both in two-party and multi-party settings based on Bayesian game. Our approach can resolve the impossible solutions to a rational secret sharing model. First, we analyze the 2-out-of-2 rational secret sharing using Bayesian game, which makes us able to consider different classes of the protocol player(for'good' and 'bad' players) and model attributes such as any other parties' preferences and beliefs that may affect the outcome of the game. Thus, the new model makes us able to reason rational secret sharing from the perspective of Bayesian rationality, a notion that may be in some scenarios more appropriate than that defined as per pure rational. According to these analyses, we propose a Bayesian rational protocol of 2-out-of-2 secret sharing. Also, our techniques can be extended to the case of t-out-of-n Bayesian rational secret sharing easily.Our protocol is adopted only by the parties in their decision-making according to beliefs and Bayes rule, without requiring simultaneous channels and can be run over asynchronous networks. | TIAN YouLiang PENG ChangGen LIN DongDai MA JianFeng JIANG Qi JI WenJiang | 2015 | Science China(Information Sciences)2015，58，5： | 9 |
| 16 | Universally composable anonymous Hash certification model显示文摘Ideal function is the fundamental component in the universally composable security model. However, the certification ideal function defined in the universally composable security model realizes the identity authentication by binding identity to messages and the signature, which fails to characterize the special security requirements of anonymous authentication with other kind of certificate. Therefore, inspired by the work of Marten, an anonymous hash certification ideal function and a more universal certificate CA model are proposed in this paper. We define the security requirements and security notions for this model in the framework of universal composable security and prove in the plain model (not in the random-oracle model) that these security notions can be achieved using combinations of a secure digital signature scheme, a symmetrical encryption mechanism, a family of pseudorandom functions, and a family of one-way collision-free hash functions. Considering the limitation of wireless environment and computation ability of wireless devices, this anonymous Hash certification ideal function is realized by using symmetry primitives. | ZHANG Fan MA JianFeng SangJae MOON | 2007 | Science in China(Series F)2007，50，3： | 9 |
| 17 | Provable Efficient Certificateless Group Key Exchange Protocol显示文摘Certificateless public key cryptography (CL-PKC) avoids the inherent escrow of identity-based cryptography and does not require certificates to guarantee the authenticity of public keys. Based on CL-PKC, we present an efficient constant-round group key exchange protocol, which is provably secure under the intractability of computation Diffie-Hellman problem. Our proto- col is a contributory key exchange with perfect forward secrecy and has only two communication rounds. So it is more efficient than other protocols. Moreover, our protocol provides a method to design efficient constant-round group key exchange protocols and most secret sharing schemes could be adopted to construct our protocol. | CAO Chunjie MA Jianfeng MOON Sangjae | 2007 | Wuhan University Journal of Natural Sciences2007，12，1： | 8 |
| 18 | One-Time Rational Secret Sharing Scheme Based on Bayesian Game显示文摘The rational secret sharing cannot be realized in the case of being played only once,and some punishments in the one-time rational secret sharing schemes turn out to be empty threats.In this paper,after modeling 2-out-of-2 rational secret sharing based on Bayesian game and considering different classes of protocol parties,we propose a 2-out-of-2 secret sharing scheme to solve cooperative problem of a rational secret sharing scheme being played only once.Moreover,we prove that the strategy is a perfect Bayesian equilibrium,adopted only by the parties in their decision-making according to their belief system (denoted by the probability distribution) and Bayes rule,without requiring simultaneous channels. | TIAN Youliang MA Jianfeng PENG Changgen CHEN Xi JI Wenjiang | 2011 | Wuhan University Journal of Natural Sciences2011，16，5： | 8 |
| 19 | Establishing Multi-Party Trust Architecture for DRM by Using Game-Theoretic Analysis of Security Policies显示文摘 | ZHANG Zhiyong PEI Qingqi MA Jianfeng YANG Lin | 2009 | Chinese Journal of Electronics2009，18，3： | 8 |
| 20 | A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer显示文摘The immune checkpoint blockade therapy has profoundly revolutionized the field of cancer immunotherapy. However, despite great promise for a variety of cancers, the efficacy of immune checkpoint inhibitors is still low in colorectal cancer(CRC). This is mainly due to the immunosuppressive feature of the tumor microenvironment(TME). Emerging evidence reveals that certain chemotherapeutic drugs induce immunogenic cell death(ICD), demonstrating great potential for remodeling the immunosuppressive TME. In this study, the potential of ginsenoside Rg3(Rg3) as an ICD inducer against CRC cells was confirmed using in vitro and in vivo experimental approaches. The ICD efficacy of Rg3 could be significantly enhanced by quercetin(QTN) that elicited reactive oxygen species(ROS). To amelioratein vivo delivery barriers associated with chemotherapeutic drugs, a folate(FA)-targeted polyethylene glycol(PEG)-modified amphiphilic cyclodextrin nanoparticle(NP) was developed for co-encapsulation of Rg3 and QTN. The resultant nanoformulation(CD-PEG-FA.Rg3.QTN) significantly prolonged blood circulation and enhanced tumor targeting in an orthotopic CRC mouse model, resulting in the conversion of immunosuppressive TME. Furthermore, the CD-PEG-FA.Rg3.QTN achieved significantly longer survival of animals in combination with Anti-PD-L1. The study provides a promising strategy for the treatment of CRC. | Dandan Sun Yifang Zou Liu Song Shulan Han Hao Yang Di Chu Yun Dai Jie Ma Caitriona M.O’Driscoll Zhuo Yu Jianfeng Guo | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 8 |
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