|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Body-mass index correlates with severity and mortality in acute pancreatitis: A meta-analysis显示文摘BACKGROUND Obesity rates have increased sharply in recent decades. As there is a growing number of cases in which acute pancreatitis(AP) is accompanied by obesity, we found it clinically relevant to investigate how body-mass index(BMI) affects the outcome of the disease.AIM To quantify the association between subgroups of BMI and the severity and mortality of AP.METHODS A meta-analysis was performed using the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA) Protocols. Three databases(PubMed, EMBASE and the Cochrane Library) were searched for articles containing data on BMI, disease severity and mortality rate for AP. Englishlanguage studies from inception to 19 June 2017 were checked against our predetermined eligibility criteria. The included articles reported all AP cases with no restriction on the etiology of the disease. Only studies that classified AP cases according to the Atlanta Criteria were involved in the severity analyses. Odds ratios(OR) and mean differences(MD) were pooled using the random effects model with the DerSimonian-Laird estimation and displayed on forest plots. The meta-analysis was registered in PROSPERO under number CRD42017077890.RESULTS A total of 19 articles were included in our meta-analysis containing data on 9997 patients. As regards severity, a subgroup analysis showed a direct association between AP severity and BMI. BMI < 18.5 had no significant effect on severity;however, BMI > 25 had an almost three-fold increased risk for severe AP in comparison to normal BMI(OR = 2.87, 95%CI: 1.90-4.35, P < 0.001). Importantly,the mean BMI of patients with severe AP is higher than that of the non-severe group(MD = 1.79, 95%CI: 0.89-2.70, P < 0.001). As regards mortality, death rates among AP patients are the highest in the underweight and obese subgroups. A BMI < 18.5 carries an almost two-fold increase in risk of mortality compared to normal BMI(OR = 1.82, 95%CI: 1.32-2.50, P < 0.001). However, the chance of mortality is almost equal in the normal BMI and BMI 25-30 subgroups. A BMI >30 results in a three times higher risk of mortality in comparison to a BMI < 30(OR = 2.89, 95%CI: 1.10-7.36, P = 0.026).CONCLUSION Our findings confirm that a BMI above 25 increases the risk of severe AP, while a BMI > 30 raises the risk of mortality. A BMI < 18.5 carries an almost two times higher risk of mortality in AP. | Dalma Dobszai Péter Mátrai Zoltan Gyongyi Dezso Csupor Judit Bajor Balint Eross Alexandra Mikó Lajos Szakó Agnes Meczker Roland Hágendorn Katalin Márta Andrea Szentesi Péter Hegyi on behalf of the Hungarian Pancreatic Study Group | 2019 | World Journal of Gastroenterology2019，25，6： | 11 |
| 2 | Intralesional steroid is beneficial in benign refractory esophageal strictures:A meta-analysis显示文摘AIM To analyze the effect of intralesional steroid injections in addition to endoscopic dilation of benign refractory esophageal strictures.METHODS A comprehensive search was performed in three databases from inception to 10 April 2017 to identify trials, comparing the efficacy of endoscopic dilation to dilation combined with intralesional steroid injections. Following the data extraction, meta-analytical calculations were performed on measures of outcome by the randomeffects method of Der Simonian and Laird. Heterogeneity of the studies was tested by Cochrane's Q and I^2 statistics. Risk of quality and bias was assessed by the Newcastle Ottawa Scale and JADAD assessment tools.RESULTS Eleven articles were identified suitable for analyses, involving 343 patients, 235 cases and 229 controls in total. Four studies used crossover design with 121 subjects enrolled. The periodic dilation index(PDI) was comparable in 4 studies, where the pooled result showed a significant improvement of PDI in the steroid group(MD:-1.12 dilation/month, 95% CI:-1.99 to -0.25 P = 0.012; I^2 = 74.4%). The total number of repeat dilations(TNRD) was comparable in 5 studies and showed a non-significant decrease(MD:-1.17, 95%CI:-0.24-0.05, P = 0.057; I^2 = 0), while the dysphagia score(DS) was comparable in 5 studies and did not improve(SMD: 0.35, 95%CI:-0.38, 1.08, P = 0.351; I^2 = 83.98%) after intralesional steroid injection.CONCLUSION Intralesional steroid injection increases the time between endoscopic dilations of benign refractory esophageal strictures. However, its potential role needs further research. | László Szapáry Benedek Tinusz Nelli Farkas Katalin Márta Lajos Szakó Agnes Meczker Roland Hágendorn Judit Bajor Aron Vincze Zoltan Gyongyi Alexandra Mikó Dezso Csupor Péter Hegyi Balint Eross | 2018 | World Journal of Gastroenterology2018，24，21： | 7 |
| 3 | Solid phase microextraction capillary gas chromatography combined with furnace atomization plasma emission spectrometry for speciation of mercury in fish tissues显示文摘 | Patricia G Reinaldo C C Zoltan M | 2003 | Spectrochimica Acta Part B2003，，58： | 1 |
| 4 | Determination of selenoamino acids by high-performance liquid chomatography-hydranlia high pressure nebulization -a tomic fluorescence spectrometry显示文摘 | ERZSEBET P ZOLTAN M PETER F | 1999 | J Anal at Spectrom1999，14，6： | 1 |
| 5 | Bcl-2 founction in an antioxidant pathway to prevent apoptosis显示文摘 | David M Zoltan N Liu XM | 1993 | Cell1993，75，2： | 1 |
| 6 | Changes of serum carotenoids in patients with esophageal,gastric,hepatocellular,pancreatic and colorectal cancer显示文摘 | Gyorgy R J Zoltan M Gyula T | 2001 | J of Physiology2001，95，： | 1 |
| 7 | Origin site of calcium release and calcium oscillation in Frog sympathetic neurons显示文摘 | McDonough S I Cseresnyes Zoltan Schneider M F | 2000 | J Neurosci2000，20，11： | 1 |
| 8 | In situ generation of Pd nanoparticles in MCM-41 and catalytic applications in liquid-phase alkyne hydrogenations 显示文摘 | AGNES M BULCS U R ZOLTAN K | 2007 | Journal of Molecular Catalysis A2007，264，： | 1 |
| 9 | PGC-1[alpha] promotes recovery after acute kidney injury during systemic inflammation in mice显示文摘 | Tran Mei Tam Denise Bardia Amit Bhasin Manoj Rowe Glenn C Kher Ajay Zsengeller Zsuzsanna K Akhavan-Sharif M Reza Khankin Eliyahu V Saintgeniez Magali David Sascha Burstein Deborah Karumanchi S Ananth Stillman Isaac E Arany Zoltan Parikh Sa | 2011 | Journal of Clinical Investigation2011，，10： | 1 |
| 10 | Knowledge spillover entrepreneurship in an endogenous growth model显示文摘 | Zoltan J Sanders M | 2013 | Small Business Economics2013，41，： | 1 |
| 11 | Expression of a novel-type small praline-rich protein gene of alfalfa is induced by 2,4-dichlorophenoxiacetic acid in dedifferentiated callus cells显示文摘 | Janos G Kingga N Zoltan M | 1997 | Plant Molecular Biology1997，34，： | 1 |
| 12 | Determination of trace manganese andNi in neem oil by ETA-AAS with emulsion sample introduction 显示文摘 | Benzo Z Zoltan T Murillo M | 2006 | The American Oil Chemists''society2006，83，5： | 1 |
| 13 | Immunocytochemical localization of acyl-lipid desaturases in cyanobacterlal cells: Evidence that both thylakoid membranes and cytoplasmic membranes are sites of lipid desaturation显示文摘 | Laszlo M Dmitry A L Zoltan G | 1996 | Plant Biology1996，93，10： | 1 |
| 14 | Usefulness of ultrasound lung comet as a nonradiologic sign of extravascular lung water显示文摘 | Zoltan J Simonetta M Vincenzo C | 2004 | The American Journal of Cardiology2004，93，： | 1 |
| 15 | Solid phase microextraction as a tool for trace element determination 显示文摘 | M Zoltan S Ralph | 2003 | Comprehensive Analytical Chemistry2003，，41： | 1 |
| 16 | The so- cial value of productive entrepreneurship显示文摘 | Zoltan J A Boardman M C Mcneely C L | 2013 | Small Business Economics2013，40，3： | 1 |
| 17 | Conditioned refl exes inexperimental lymphogenic encephalopathy and theirtherapeutic modification by coumarin from Melilotusofficinalis显示文摘 | Zoltan O T Foldi M | 1970 | Arzneimittel Forschung1970，20，3： | 1 |
| 18 | Behavior of thehematocrit value in experimental lymphangiothrom-bophlebitis显示文摘 | Foldi M Zoltan O T Piukovich I | 1970 | Arzneimittel Forschung1970，20，11： | 1 |
| 19 | Whole-body cortisol is an indicator of crowding stress in adult zebrafish, Danio Rerio 显示文摘 | JENNIFER M R GRANT W F ZOLTAN M V | 2006 | Aquaculture2006，258，： | 1 |
| 20 | Effect of coumarin from Melilotusofficinalis on the convulsion threshold of the centralnervous system of rats and guinea pigs显示文摘 | Zoltan O T Foldi M | 1970 | ArzneimittelForschung1970，20，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员