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| 1 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011,,3: | 4 |
| 2 | Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis显示文摘BACKGROUND Rotator cuff pathology is a very common source of shoulder pain.Similarly,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar symptoms.Surgical management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of GHOA.AIM To evaluate if a relationship exists between outcomes of RCR in the setting of GHOA.METHODS This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between 2010-2017.Patients were stratified based on rotator cuff tear size and glenohumeral osteoarthritis severity.Cohorts were paired 1:1 with patients without glenohumeral osteoarthritis.Patients included had a minimum two year follow-up.Rate of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were collected.RESULTS A total of 142 patients were included.The number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without GHOA.Following rotator cuff repair,both groups showed favorable patientreported outcomes.CONCLUSION Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis. | Ian S Hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman | 2022 | World Journal of Orthopedics2022,13,7: | 2 |
| 3 | Cardiac implications of thrombotic thrombocytopenic purpura显示文摘Thrombotic thrombocytopenic purpura(TTP) is a multisystem disorder that essentially can affect any organ in the human body. The hallmark of the pathogenesis in TTP is the large von Willebrand factor multimers on plateletmediated micro-thrombi formation, leading to microvascular thrombosis.Autopsy studies showed that cardiac arrest and myocardial infarction are the most common immediate causes of death in these patients. Clinical manifestations of cardiac involvement in TTP vary dramatically, from asymptomatic elevation of cardiac biomarkers, to heart failure, MI and sudden cardiac death. There is limited knowledge about optimal cardiac evaluation and management in patients with TTP. The absence of typical cardiac symptoms,combined with complicated multi-organ involvement in TTP, may contribute to the under-utilization of cardiac evaluation and treatment. Prompt diagnosis and timely initiation of effective therapy could be critically important in selected cases. Based on our experience and this review of the literature, we developed several recommendations for focused cardiac evaluation for patients with acute TTP:(1) patients with suspected or confirmed TTP should be screened for the potential presence of cardiac involvement with detailed history and physical,electrocardiogram and cardiac enzymes;(2) clinical deterioration of TTP patients warrants immediate cardiac reevaluation;(3) TTP patients with clinical evidence of cardiac involvement should be monitored for telemetry, cardiac biomarkers and evaluated with transthoracic echocardiography. These patients require urgent targeted TTP treatment as well as cardiac-specific treatment. Aspirin therapy is indicated for all TTP patients. Since epicardial coronary artery involvement is rare, cardiac catheterization is usually not required, given the high risk for hemorrhage and kidney injury;(4) we recommend evidence-based medical therapy for ischemic symptoms and heart failure. TTP patients with evidence of cardiac involvement would also benefit from routine cardiology follow up during remission. | Szymon L Wiernek Bo Jiang Gregory M Gustafson Xuming Dai | 2018 | World Journal of Cardiology2018,10,12: | 2 |
| 4 | Elastic wave velocities in heterogeneous and porous media 显示文摘 | Wyllie M R J Gregory A R Gardner L W | 1956 | Geophysics1956,21,1: | 1 |
| 5 | Thermosensitive gold nanoparticles显示文摘 | ZHU M Q WANG L Q GREGORY J | 2004 | Journal of the American Chemical Society2004,126,9: | 1 |
| 6 | Cyclooxygenase-2 inhi-bition delays the attainment of peak woven bone formationfollowing four-point bending in the rat 显示文摘 | GREGORY L S FORWOOD M R | 2007 | Caleif Tiss2007,80,3: | 1 |
| 7 | Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013显示文摘 | Meijer A Rebelo-de-Andrade H Correia V Besselaar T Drager-Dayal R Fry A Gregory V Gubareva L Kageyama T Laekenby A Lo J Odagiri T Pere- yaslov D Siqueira M M Takashita E Tashiro M Wang D Wong S Zhang W Daniels R S Hurt A C | 2014 | An- tiviral Research2014,110,: | 1 |
| 8 | Genetic and phenotypic (co)variances for growth and carcass traits of purebred and composite populations of beef cattle 显示文摘 | GREGORY K E CUNDIFF L V KOCH R M | 1995 | Journal of Animal Science1995,73,: | 1 |
| 9 | Aging effect on the reflectivity measurements of polychloroprene matrices containing carbon black and carbonyl-iron powder显示文摘 | Pinho M S Gregori M L Nunes R C R Soares B G | 2001 | Polymer Degradation and Stability2001,73,: | 1 |
| 10 | Assessing fractionated spacecraft value propositions for earth imaging space missions 显示文摘 | Gregory M O Annalisa L W | 2011 | Journal of Spacecraft and Rocket2011,48,6: | 1 |
| 11 | Elastic wave velocities in heterogeneous and porous media 显示文摘 | Wyllie M R J Gregory A R and Gardner L W | 1956 | Geophysics1956,21,1: | 1 |
| 12 | Thyrotropin-releasing hormone time-dependently influences thyrotropin mieroheterogeneity--an in vivo study in euthyroidism显示文摘 | Schaaf L Theodoropoulou M Gregori A | 2000 | J Endocrinol2000,166,1: | 1 |
| 13 | Elastic wave velocities in heterogeneous and porous media显示文摘 | Wyllie M R J Gregory A R Gardner L W | 1956 | Geophysics1956,21,1: | 1 |
| 14 | Age and rcial/ethnic differences in materal,fetal,and placental conditions in laboring patients显示文摘 | Gregory K D Korst L M | 2003 | Am J Obstet Gynecol2003,188,6: | 1 |
| 15 | An experimental investigation of factors affecting elastic wave velocities in porous media显示文摘 | Wyllie M R J Gregory A R and Gardner L W | 1958 | 23 (3) : 459-4931958,23,3: | 1 |
| 16 | Emission analysis of alternative diesel fuels using a compression ignition benchtop engine generator显示文摘 | GREGORY S B RACHEL L M MICHAEL P H | 2011 | Energy & Fuels2011,25,: | 1 |
| 17 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011,58,18: | 1 |
| 18 | Elastic wave velocities in heterogeneous and porous media显示文摘 | Wyllie M R J Gregory A R Gardner L W | 1956 | Geophysics1956,21,129: | 1 |
| 19 | Ubiquitin, cellular inclusions and their role in neurodegeneration 显示文摘 | Alves-Rodrigues A Gregori L Figueiredo-Pereira M E | 1998 | Trends Neurosci1998,21,12: | 1 |
| 20 | Comparing agro ecosystems: Effects of cropping and tillage patterns on soil water, energy use and productivity显示文摘 | Gregory M M Shea K L Bakko E B | 2005 | Renewable Agriculture and Food Systems2005,20,2: | 1 |