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| 1 | Mastoid obliteration and reconstruction techniques:A review of the literature显示文摘Objective To review the published literature related to the different obliteration and reconstruction techniques in the management of the canal wall down mastoidectomy.Methods A PubMed(Medline)and LILACS databases as well as crossed references search was performed with the following Mesh terms:“cholesteatoma”,“cholesteatoma-middle ear”,“otitis media”,“otitis media,suppurative”,“mastoiditis”,“mastoidectomy”,“canal wall down mastoidectomy”,“radical mastoidectomy”,“mastoid obliteration”and crossed references.Inclusion criteria were adult patients subject to mastoid cavity obliteration and posterior canal wall reconstruction.The technique and materials used,anatomic and functional results,complications,recurrence rates,and changes in quality of life,were analyzed.A total of 94 articles were screened,38 were included for full-text detailed review.Results Twenty-one articles fulfilled the inclusion criteria.Techniques and materials used for canal wall reconstruction,tympanoplasty,and ossiculoplasty were varied and included autologous,biosynthetic,or both.Auditory results were reported in 16 studies and were inconsistent.Three studies reported improvement in the quality of life using the GBI scale.Follow-up time ranged from 1 to 83 months.Eleven articles used imaging studies to evaluate postoperative disease recurrence.The highest recurrence rate reported for cholesteatoma after obliteration was 19%.The most frequently reported complications were retraction pockets and transient otorrhea.Conclusion Plenty of techniques combining grafts and other materials have been used to overcome mastoidectomy cavity problems.So far,it is still not possible to standardize an ideal procedure.The available level of evidence for this topic is low and limited. | Michelle Lupa Mendlovic Daniella Alejandra Monroy Llaguno Ivan Hermann Schobert Capetillo Juan Carlos Cisneros Lesser | 2021 | Journal of Otology2021，16，3： | 5 |
| 2 | The application of endoscopic sinus surgery to the treatment of recurrent sinus barotrauna 显示文摘 | O'REILLY B J LUPA H MCRAE A | 1996 | Clin Otolargngol Allied Sci1996，21，： | 1 |
| 3 | WIPI-1alpha (WIPI49),a member of the novel 7-bladed WIPI protein family,is aberrantly expressed in human cancer and is linked to starvation-induced autophagy显示文摘 | Proikas-Cezanne T Waddell S Gaugel A Frickey T Lupas A Nordheim A | 2004 | Oncogene2004，58，： | 1 |
| 4 | The HHpred interactive server for protein homology detection and structure prediction 显示文摘 | Soding J Biegert A and Lupas A N | 2005 | Nucleic Acids Research2005，33，： | 1 |
| 5 | Linear Multiuser Detectors for Synchronous Code-Division Multiple-Access Channels 显示文摘 | LUPAS R VERDU S | 1989 | IEEE Trans Inform Theory1989，35，1： | 1 |
| 6 | Lung NF-κB activation and neutrophil recruitment require IL-1 and TNF receptor signaling during pneumocoecal pneumonia 显示文摘 | Jones MR Simms BT Lupa MM | 2005 | J Immunol2005，175，11： | 1 |
| 7 | Predicting coiled coils from protein sequences显示文摘 | Lupas A Van Dyke M Stock J | 1991 | Science1991，252，5009： | 1 |
| 8 | Predicting Coiled Coils from Protein Sequences显示文摘 | Van Dyke M Stock | 1991 | Science1991，252，： | 1 |
| 9 | Linear multiuser detectors for synchronous code-division multiple access channels显示文摘 | Lupas R Verdu S | 1989 | IEEE Trans on Information Theory1989，35，1： | 1 |
| 10 | Predicting coiled coils from protein sequences 显示文摘 | Lupas A Van Dyke M Stock J | 1991 | Science1991，252，5010： | 1 |
| 11 | Predicting coiled coils from protein sequences 显示文摘 | Lupas A Van Dyke M Stock J | 1991 | Science1991，252，5009： | 1 |
| 12 | Predicting coiled coilsfrom protein sequences显示文摘 | Lupas A Van Dyke M Stock J | 1991 | Science1991，252，5009： | 1 |
| 13 | Linear multiuser detectors for syn-chronous code-division multiple-access channels显示文摘 | Lupas R VerdúS | | 0，，01： | 1 |
| 14 | Predicting coiled coils from protein sequences显示文摘 | LUPAS A DYKE M V STOC J | 1991 | Science1991，252，5009： | 1 |
| 15 | Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis显示文摘 | MULLER TAUBENBERGER A LUPAS A N LI H | 2001 | EMBO J2001，20，23： | 1 |
| 16 | Near-far resistance of multi-user detectors in asynchronous channels 显示文摘 | Lupas R Verdu S | 1990 | IEEE Transactions on Communications1990，38，4： | 1 |
| 17 | Linear multiuser detectors for synchronous code-division multiple-access ehannels 显示文摘 | LUPAS R VERDU S | 1989 | IEEE Transactions on Information Theory1989，35，1： | 1 |
| 18 | Calreticulin and calnexin in the endoplasmic reticulum are important for phagocytosis显示文摘 | Miiller-Taubenberger A Lupas A N Li H | 2001 | The EMBO Journal2001，20，23： | 1 |
| 19 | The role of proteoglycans in Schwann cell/astrocyte interactions and in regeneration failure at PNS/CNS interfaces显示文摘 | Grimpe B Pressman Y Lupa MD | | 0，，： | 1 |
| 20 | Approximationseigenschaften der gammaoperatoren 显示文摘 | LUPAS A MLLER M | 1967 | Math Z1967，98，： | 1 |
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