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15篇 您的检索式:作者名="Luca Stocchi"
    题名 作者 年代 出处 被引量
1Laparoscopic colorectal resection for cancer: effects of conversion on long-term oncologic outcomes显示文摘Matteo Rottoli Luca Stocchi Dan Geisler Ravi Kiran 2012Surgical Endoscopy2012,,7:2
2Current indications and role of surgery in the management of sigmoid diverticulitis显示文摘Sigmoid diverticulitis is a common disease which carries both a significant morbidity and a societal economic burden.This review article analyzes the current data regarding management of sigmoid diverticulitis in its variable clinical presentations.Wide-spectrum antibiotics are the standard of care for uncomplicated diverticulitis.Recently published data indicate that sigmoid diverticulitis does not mandate surgical management after the second episode of uncomplicated disease as previously recommended.Rather,a more individualized approach,taking into account frequency,severity of the attacks and their impact on quality of life,should guide the indication for surgery.On the other hand,complicated diverticular disease still requires surgical treatment in patients with acceptable comorbidity risk and remains a life-threatening condition in the case of free peritoneal perforation.Laparoscopic surgery is increasingly accepted as the surgical approach of choice for most presentations of the disease and has also been proposed in the treatment of generalized peritonitis.There is not sufficient evidence supporting any changes in the approach to management in younger patients.Conversely,the available evidence suggests that surgery should be indicated after one attack of uncomplicated disease in immunocompromised individuals.Uncommon clinical presentations of sigmoid diverticulitis and their possible association with inflammatory bowel disease are also discussed.Luca Stocchi 2010World Journal of Gastroenterology2010,16,7:1
3Total abdominal colectomy for severe ulcerative colitis: does the laparoscopic approach really have benefit?显示文摘Jinyu Gu Luca Stocchi Feza H. Remzi Ravi P. Kiran 2014Surgical Endoscopy2014,,:1
4Is laparoscopic surgery for recurrent Crohn’s disease beneficial in patients with previous primary resection through midline laparotomy? A case-matched study显示文摘Erman Aytac Luca Stocchi Feza H. Remzi Ravi P. Kiran 2012Surgical Endoscopy2012,,:1
5Less Than 12 Nodes in the Surgical Specimen After Total Mesorectal Excision Following Neoadjuvant Chemoradiation: It means more than you think!显示文摘Luiz Felipe de Campos-Lobato Luca Stocchi Jo?o Batista de Sousa Martin Buta Ian C. Lavery Victor W. Fazio David W. Dietz Matthew F. Kalady 2013Annals of Surgical Oncology2013,,11:1
6Laparoscopic Surgery for Patients with Crohn’s Colitis: A Case-matched Study显示文摘Andre da Luz Moreira Luca Stocchi Feza H. Remzi Daniel Geisler Jeffery Hammel Victor W. Fazio 2007Journal of Gastrointestinal Surgery2007,,11:1
7Long-term outcomes of laparoscopic versus open ileocolic resection for Crohn’s disease: Follow-up of a prospective randomized trial显示文摘Luca Stocchi Jeffrey W. Milsom Victor W. Fazio 2008Surgery2008,,:1
8Downstaging Without Complete Pathologic Response After Neoadjuvant Treatment Improves Cancer Outcomes for cIII but not cII Rectal Cancers显示文摘Luiz Felipe de Campos-Lobato MD Luca Stocchi MD Andre da Luz Moreira MD Matthew F. Kalady MD Daniel Geisler MD David Dietz MD Ian C. Lavery MD Feza H. Remzi MD Victor W. Fazio MD 2010Annals of Surgical Oncology2010,,7:1
9Management of colorectal neoplasia during pregnancy and in the postpartum period显示文摘AIM: To report our experience on management of colorectal neoplasia during pregnancy and in the postpartum period.METHODS: Patients who were diagnosed with colorectal cancer during pregnancy or in the postpartum period(< 6 mo), between 8/1997 and 4/2013, in our department were reviewed. Patient characteristics, operations, fetal health and follow-up during pregnancy, type of delivery and oncologic outcomes were analyzed.RESULTS: Eight patients met our study criteria. Median age at the time of diagnosis of colorectal cancer was 31 years. Median follow-up after surgery was 36 mo. Median duration of symptoms before diagnosis was 16 wk. Three patients were diagnosed with colorectal cancer during pregnancy and underwent surgery prior to delivery. None of the patients received adjuvant treatment during pregnancy. Five patients were diagnosed with colorectal cancer within a median of 2.1 mo after delivery and underwent surgery. No adverse neonatal outcomes were noted. All deliveries were at term(2 cesarean sections) except for one preterm delivery following low anterior resection on the 34 th week of pregnancy.CONCLUSION: There has been a significant delay in the diagnosis of colorectal cancer which is probably due to overlap of symptoms and signs between these tumors and a normal pregnancy. Surgery for colorectal cancer during pregnancy can be performed safely without compromisingmaternal and fetal outcomes.Erman Aytac Gokhan Ozuner Ozgen Isik Emre Gorgun Luca Stocchi 2016World Journal of Gastrointestinal Oncology2016,8,7:1
10Risk of recurrence and long-term outcomes after colonic diverticular bleeding显示文摘Erman Aytac Luca Stocchi Emre Gorgun Gokhan Ozuner 2014International Journal of Colorectal Disease2014,,3:1
11Laparoscopic Colorectal Resection in the Obese Patient显示文摘Sean Martin Luca Stocchi 2011Clinics in Colon and Rectal Surgery2011,,04:1
12Laparoscopic surgery for ulcerative colitis显示文摘Luca Stocchi M D 2010Clincolon R ectal Surg2010,23,4:1
13围手术期输血增加克罗恩病术后感染性并发症发生率显示文摘背景:我们中心的数据显示,输血会增加克罗病术后并发症。本研究旨在基于美国外科医师协会的国家手术质量提升计划(ACS NSQIP)这个大数据平台,验证围手术期输血与克罗恩病患者术后感染性并发症的关系。方法:从NSQIP数据库中提取2005-2013年间的克罗恩病手术病例的临床资料。参照ACS NSQIP指南对相关的临床变量进行定义和分层。主要结局指标是感染性并发症,包括外科手术部位感染(SSI,包括切口浅部感染、切口深部感染、器官/腔隙感染)、肺炎、泌尿系感染、脓毒血症及中毒性休克。对术后感染的危险因素进行多因素分析。结果:10100例病例纳入研究,其中611例(6.0%)接受了围手术期输血。输血患者年龄相对更大,体质量更轻,且功能依赖(即生活不能完全自理,一定程度上需要依赖他人)的比例相对更高。与未输血患者相比,输血患者术后感染性并发症发生率较高,包括切口浅部感染(10.8%vs.7.4%,P¼0.002),切口深部感染(3.3%vs.1.6%,P¼0.003),器官/腔隙感染(14.2%vs.5.4%,P<0.001),肺炎(3.8%vs.1.3%,P<0.001),泌尿系感染(3.9%vs.2.2%,P¼0.006),脓毒血症(11.5%vs.4.5%,P<0.001),中毒性休克(3.1%vs.0.8%,P<0.001)。多因素分析结果显示,术中和/或术后输血是术后感染性并发症的独立危险因素(OR¼2.2,95%CI:1.8-2.7,P<0.001),每增加一个单位的红细胞输入,术后感染风险增加30%(OR¼1.3,95%CI:1.2-1.5)。其他独立危险因素还包括吸烟、心脏病、糖尿病、高血压和服用类固醇类药物。但术前输血并不是术后感染的危险因素。结论:术中和/或术后输血会增加克罗恩病术后感染性并发症的发生风险,但术前输血对此并无影响。因此,临床上需合理选择输血时机并仔细权衡输血的风险与获益。Nan Lan Luca Stocchi Yi Li Bo Shen 2018Gastroenterology Report2018,6,2:0
14术后内脏脂肪组织及体质指数过度增加会引起回肠储袋不良结 局显示文摘背景:全结直肠切除、回肠储袋肛管吻合(IPAA)术后,内脏脂肪组织(VAT)的变化对于预后的影响,目前尚无相关报道。本项回顾性队列研究旨在评估VAT过度增加对行IPAA术的炎性肠病(IBD)患者临床结局的影响。方法:收集2002-2014年间我们的前瞻性储袋炎登记病例中,储袋手术后至少接受了2次序贯CT检查的患者。通过CT图像分析计算内脏脂肪面积(VFA)。将VAF增加>15%者归入研究组,VAF增长不足15%者作为对照组。储袋不良结局定义为在初次CT检查后出现储袋慢性炎症进展(慢性储袋炎、慢性封套炎或储袋克罗恩病)、储袋窦道形成或储袋失败,前两项统称为储袋混合事件。结果:在1564例登记病例中,59例(3.8%)在储袋手术后接受了至少2次CT检查,其中29例(49.2%)归入研究组,30例(50.8%)作为对照组。全组病例初次CT检查至最近一次CT检查的中位间隔时间为552天(312~598天)。两组患者储袋慢性炎症进展发生率分别为13.8%vs 3.3%(p=0.195),储袋窦道形成发生率分别为10.3%vs 0%(P=0.112),储袋混合事件发生率分别为24.1%vs 3.3%(P=0.026),储袋失败率分别为10.3%vs 6.7%(P=0.671)。Kaplan-Meier曲线显示,体质指数(BMI)过度增加(>10%)患者无储袋失败生存时间明显缩短(P=0.011)。多因素逐步回归分析显示,VAT过度增加是储袋不良结局的独立危险因素(OR=12.608,95%CI:1.190~133.538,P=0.035)。结论:在本组回肠储袋患者队列中,储袋手术后VAT或BMI的过度增加长远来看都可能导致储袋不良结局。Ganglei Liu Xianrui Wu Yi Li Yuanyi Rui Luca Stocchi Feza HRemzi Bo Shen 2017Gastroenterology Report2017,5,1:0
15接受术后化疗的炎性肠病相关结直肠癌患者的复发率与生存率:一项比较研究显示文摘背景与目的:炎性肠病(IBD)患者具有一定结直肠癌发生风险。研究显示,IBD相关结直肠癌与非IBD相关结直肠癌在肿瘤发生机制和组织形态学上存在差异,提示其肿瘤行为和治疗反应也可能有所不同。我们旨在比较接受术后化疗IBD相关与非IBD相关的结直肠癌患者肿瘤复发及生存率的差异。方法:检索Cleve?land临床中心结直肠癌数据库,筛选出1994-2010年间的65例IBD相关结直肠癌且接受了术后辅助化疗的患者,排除21例临床资料不完整者。按照年龄、手术目的、肿瘤部位、肿瘤病理分级、AJCC分期和T分期,对IBD相关和非IBD相关的结直肠癌患者进行1:4的病例匹配分组。分别采用竞争风险模型和Cox回归模型来评估IBD对无病生存和总体生存的影响。结果:44例IBD相关和176例非IBD相关的结直肠癌患者完成匹配。在IBD组患者中,29例(66%)为溃疡性结肠炎,14例(19%)为克罗恩病,1例(2%)诊断为不确定型肠炎。IBD平均诊断年龄为(28.1±14.5)岁,IBD诊断至结直肠癌治疗的平均间期为(21.5±12.6)年。10例(23%)IBD组患者出现了肿瘤复发,而非IBD组则有34例(19%)复发(P=0.074)。IBD组与非IBD组患者无瘤生存率(HR=0.60;95%CI:0.35~1.05;P=0.074)和总体生存率(HR=0.87;95%CI:0.54~1.4;P=0.58)的差异均无统计学意义。结论:接受术后化疗的IBD相关结直肠癌患者,其复发率与生存率与非IBD相关结直肠癌患者相当。有必要行进一步的前瞻性研究来证实这些发现,以指导治疗决策。Mohannad Dugum Jingmei Lin Rocio Lopez Bassam Estfan Elena Manilich Luca Stocchi Bo Shen Xiuli Liu 2017Gastroenterology Report2017,5,1:0
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