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| 1 | 肥胖对全髋置换术后假体周围骨溶解影响的5年和10年随访观察显示文摘背景:全髋关节置换术后最主要的远期并发症是假体周围的骨溶解。相当多的接受关节置换术的患者为体型肥胖者。目前认为,导致骨溶解的危险因素包括患者的活动、植入物的类型以及固定质量等。但关于肥胖因素对骨溶解的影响鲜见相关文献报道,而且颇受争议。本文的目的是评估肥胖对全髋关节骨水泥型假体柄置换术后5年和10年骨溶解的危险因素;其次是对临床结果及患者的满意度作出评价。方法:我们对1996至2003午期间行第三代骨水泥型假体柄全髋关节置换术的患者进行前瞻性研究。所有患者均于术后5年或10年进行随访观察,获取X线、体重指数(BMI:〈25kg/m^2=正常,25~29.9kg/m^2=超重,≥30kg/m^2=肥胖)资料以及髋关节活动度情况。对活动度的评估采用洛杉矶加利福尼亚大学(UCLA)评分方法予以评定。临床结果采用Harris髋关节评分系统和Merled’Aubign6和Postel评分系统进行分析。结果:本文对433例患者中503髋关节置换术进行研究,其中241髋(47.9%)于术后5年,262髋(52.1%)于术后10年进行评估。181髋正常体重患者中的24髋(13.3%)、205髋超重患者中的11髋(5.4%)以及117髋肥胖患者中的9髋(7.7%)发生了骨溶解,共44髋。正常体重患者髋关节活动度最高【平均UCLA活动评分(±标准差)为(5.5+2.0)分];肥胖患者评分最低[平均UCLA活动评分为(5.0±1.7)分]。当调整了活动度、骨水泥质量、患者年龄和性别因素后,肥胖患者发生骨溶解的概率并不比超重患者高(调整比值比为1.4,95%置信区间为0.6-3.7),而发现正常体重患者发生股骨骨溶解的风险明显高于超重患者(调整比值比为2.6,95%置信区间为1.2-5.7)。各组之间临床结果没有显著性差异。结论:我们发现肥胖患者在行骨水泥型股骨柄全髋置换术后5年和10年后,假体周围骨溶解的风险并未增加;而正常体重患者骨溶解的发生率反而最高。 | Anne Lubbeke Guido Garavaglia Christophe Barea Constantinos Roussos 俞鹏飞(译) 姜宏(译) | 2010 | 中华骨科杂志2010，30，12： | 4 |
| 2 | Treatment of reverse o6-lique and transverse interochanteric fractures with the use of an intr-amedullary nail or a 95 0 screw-plate显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surg(Am)2002，84，3： | 1 |
| 3 | Treatment of re- verse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or a 95 degrees screw - plate : a prosepec- tive, randomized study 显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surg (Am)2002，84，： | 1 |
| 4 | Revision total hip arthroplasty in patients 80 years or older显示文摘 | Lubbeke A Roussos C Barea C | 2012 | J Arthroplasty2012，27，6： | 1 |
| 5 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intramedullarynail or a 95 degrees screw - plate, a prospective randomized study 显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surgery(Am)2002，84，： | 1 |
| 6 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or a 95 degrees screw-plate : a prospective, randomized study 显示文摘 | Sadowski C Lubbeke A SaudanM | 2002 | J Bone Joint Surg Am2002，84，： | 1 |
| 7 | Pertrochameric fractures: is there an advantage to an intramedullary nail? A randomised,prospective study of 206 patients comparing the dy- namic hip screw and proximal femoral nail显示文摘 | SAUDAN M LUBBEKE A SADOWSKI C | 2002 | J Orthop Trauma2002，16，： | 1 |
| 8 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intrameedullary nail or a 95 degrees screw-plate:a prospective,randomize study显示文摘 | Sadowski C Lubbeke A Saudan M | | 0，，03： | 1 |
| 9 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an interamedullary nail or a 95° screw-plate : a prospective, randomized study 显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joit Surg Am2002，84，： | 1 |
| 10 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or 95° screw-plate 显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surg (Br)2002，84，： | 1 |
| 11 | Pertrochanteric fractures: is there an advantage to an intramedullary nail? A randomized, prospective study of 206 patients comparing the dynamic hip screw and proximal femoral nail 显示文摘 | Saudan M Lubbeke A Sadowski C | 2002 | J Orthop Trauma2002，16，6： | 1 |
| 12 | Treatment of reverse oblique and transveme intertrochanteric fractures with use of an intramedullary nail or 95 screw-plate显示文摘 | Lubbeke A Saudan M | 2002 | J Bone Joint Surg(ar)2002，84，： | 1 |
| 13 | Treatmen of reverse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or a 95 degrees screw-plate: a prospective, randomized study显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | Bone Joint Surg Am2002，84，3： | 1 |
| 14 | Treatment of reverse oblique and transverse intertrochanterie fractures with use of an intramedullary nail or a 95 degrees screw-plate: a prospective, randomized study显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surg(Am)2002，84，： | 1 |
| 15 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or 95 degrees screw_plate显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surg(Br)2002，84，3： | 1 |
| 16 | Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or a 95: screw-plate: a prospective randomized study显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | J Bone Joint Surg(Am)2002，84，3： | 1 |
| 17 | Pertrochantedc fractures:is there an advantage to an intramadullary nail?:a randomized,prospective study of 206 patients comparing the dynamic hip screw and proximal femoral nail显示文摘 | Saudan M Lubbeke A SadowskiC | 2002 | J Orthop Trauma2002，16，6： | 1 |
| 18 | Treataient of fever Beoblique andtrsllsvense in tertroehantrc fractures with use of abintramedullary mailor 895 degree sscrew-plate: a prnspec-tire randomized显示文摘 | Sadowski C Lubbeke A Saudao M | 2002 | Bone Jointsurg (Am)2002，84，3： | 1 |
| 19 | Treatment of reverse oblique and transverse interrochanteric fractures with use of an intramedullary nail or 95oscrew plate 显示文摘 | Sadowski C Lubbeke A Saudan M | 2002 | Bone Joint Surg Am2002，84，： | 1 |
| 20 | Treatment of reverse and trans-verse intertrochanteric fractures with use of an intramedullary nail or 95 degrees screw-plate:a prospective,randomized study显示文摘 | SADOWSKI C LUBBEKE A SAUDAN M | 2002 | J Bone Joint Surg Am2002，84，3： | 1 |
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