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| 1 | A prospective analysis of factors that influence weight loss in patients undergoing radiotherapy显示文摘Malnutrition occurs frequently in patients with cancer.Indeed,a variety of nutritional and tumorrelated factors must be taken into account in these patients.Recognizing this relationship,we aimed to prospectively evaluate the risk factors that influence weight loss in patients undergoing radiotherapy with oral nutritional supplementation and dietetic counseling.Weight loss of 74 patients during radiotherapy and 1 month after treatment was analyzed.Parameters such as age,gender,tumor location,tumor stage,Eastern Cooperative Oncology Group performance status(ECOG PS)score,and the use of chemotherapy were analyzed to evaluate their influence on weight loss.All patients underwent oral nutritional supplementation and dietetic counseling.Forty-six(65.7%)patients lost weight,with a mean weight loss of(4.73±3.91)kg,during radiotherapy.At 1 month after treatment,45(66.2%)patients lost weight,presenting a mean weight loss of(4.96±4.04)kg,corresponding to a(6.84±5.24)%net reduction from their baseline weight.Head and neck cancer patients had a mean weight loss of(3.25±5.30)kg,whereas the remaining patients had a mean weight loss of(0.64±2.39)kg(P=0.028)during radiotherapy.In the multivariate analysis,the head and neck tumor location(P=0.005),use of chemotherapy(P=0.011),and ECOG PS score of 2-3(P=0.026)were considered independent risk factors.Nutritional status and parameters,such as tumor location(especially the head and neck),the use of chemotherapy,and the ECOG PS score,should be evaluated before radiotherapy because these factors can influence weight loss during radiotherapy and 1 month after treatment. | Jon Cacicedo Francisco Casquero Lorea Martinez-Indart Olga del Hoyo Alfonso Gomez de Iturriaga Arturo Navarro Pedro Bilbao | 2014 | Chinese Journal of Cancer2014，33，4： | 12 |
| 2 | Colorectal and interval cancers of the Colorectal Cancer Screening Program in the Basque Country (Spain)显示文摘AIM To assess proportions, related conditions and survival of interval cancer(IC).METHODS The programme has a linkage with different clinical databases and cancer registers to allow suitable evaluation. This evaluation involves the detection of ICs after a negative faecal inmunochemical test(FIT), interval cancer FIT(IC-FIT) prior to a subsequent invitation, and the detection of ICs after a positive FIT and confirmatory diagnosis without colorectal cancer(CRC) detected and before the following recommended c o l o n o s c o p y, I C-c o l o n o s c o p y. W e c o n d u c t e d a retrospective observational study analyzing from January 2009 to December 2015 1193602 invited people onto the Programme(participation rate of 68.6%).RESULTS Two thousand five hundred and eighteen cancers were diagnosed through the programme, 18 cases of IC-colonoscopy were found before the recommended follow-up(43542 colonoscopies performed) and 186 IC-FIT were identified before the following invitation of the 769200 negative FITs. There was no statistically significant relation between the predictor variables of ICs with sex, age and deprivation index, but there was relation between location and stage. Additionally, it was observed that there was less risk when the location was distal rather than proximal(OR = 0.28, 95%CI: 0.20-0.40, P < 0.0001), with no statistical significance when the location was in the rectum as opposed to proximal. When comparing the screen-detected cancers(SCs) with ICs, significant differences in survival were found(P < 0.001); being the 5-years survival for SCs 91.6% and IC-FIT 77.8%.CONCLUSION These findings in a Population Based CRC Screening Programme indicate the need of population-based studies that continue analyzing related factors to improve their detection and reducing harm. | Isabel Portillo Eunate Arana-Arri Isabel Idigoras Isabel Bilbao Lorea Martínez-Indart Luis Bujanda Inaki Gutierrez-Ibarluzea | 2017 | World Journal of Gastroenterology2017，23，15： | 2 |
| 3 | Glomus tumors of the hand: A retrospective study of 51 cases显示文摘 | Geertruyden J Lorea P Goldschmidt D | 1996 | J Hand Surg(Br)1996，21，2： | 1 |
| 4 | BvrR/BvrS-Controlled Outer Membrane Proteins Omp3a and Omp3b Are Not Essential for Brucella abortus Virulence 显示文摘 | Lorea Manterola Caterina Guzm6n Verri Esteban Chaves Olarte | 2007 | Infect Immun2007，75，10： | 1 |
| 5 | Oxidation of BN/Niealon fiber interfaces in ceramic-matrix composites and its effect on fiber strength 显示文摘 | Rigueiro J P Celemin J A Lorea J L | 1999 | Journal of the American Ceramic Society1999，82，12： | 1 |
| 6 | Glomus tumours of the hand A retrospective study of 51 cases显示文摘 | Van Geertruyden J Lorea P Goldschmidt D | 1996 | J Hand Surg Br1996，21，2： | 1 |
| 7 | Dury MRecul ungueal en urgence:nouvelle techinique de prise en charge des amputations digitales distales显示文摘 | Marin-Braun F Lorea P | | 0，，： | 1 |
| 8 | Smoking and periodontal disease severity 显示文摘 | Martinez-Canut P Lorea A Magan R | 1995 | J Clin Periodontol1995，22，10： | 1 |
| 9 | A case report of desmoid tumor of the finger显示文摘 | Berthe JV Lorea P Deprez C | 2003 | Chit Main2003，22，6： | 1 |
| 10 | Nanpoph-ase fluorite-structured CeO2-ZeO2 catalyst prepared by high-energy mechanical milling analysis of lower-temperature redox activity and oxygen storage capacity 显示文摘 | TROVARELLI A ZAMAR F LOREA J | 1997 | J Catal1997，169，2： | 1 |
| 11 | Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression显示文摘 | Fernando Vidal-Vanaclocha Lorea Mendoza Naiara Telleria Clarisa Salado María Valcárcel Natalia Gallot Teresa Carrascal Eider Egilegor Jabier Beaskoetxea Charles A. Dinarello | 2006 | Cancer and Metastasis Reviews2006，，3： | 1 |
| 12 | Camptodactyly as a spectrum of congenital deficiencies: a treatment algorithm based on clinical ex- amination显示文摘 | Foucher G Lorea P Khouri PK | 2006 | Plastic Reconstr Surg2006，12，： | 1 |
| 13 | Comparison of escitalop ram and citalop ram efficacy:a meta-analysis显示文摘 | Auquier P Robitail S L lorea PM | 2003 | Int J Psychiatry Clin Pract2003，7，： | 1 |
| 14 | Electrespinning of waterborne polyurethanes显示文摘 | LOREA BURUAGA HARITZ SARDON LOURDES IRUSTA | 2010 | Journal of Ap- plied Polymer Science2010，115，： | 1 |
| 15 | Three-dimensional multiparticle cell simulations of deformation and damage in sphere-reinforced composites 显示文摘 | Lorea J L Segurado J | 2004 | Materials Science and Engineering A2004，365，1： | 1 |
| 16 | Glomus tumours of the hand A retrospective study of 51 cases 显示文摘 | Van Geertruyden J Lorea P Goldschmidt D | 1996 | J Hand Surg Br1996，21，2： | 1 |
| 17 | Heterotopic pregnancy:two cases and a comparative review显示文摘 | Gorka B Lorea Barinaga-Rementeria Arantza LL | 2007 | Fertility and Sterility2007，87，2： | 1 |
| 18 | Anti-inflammatory effects of probiotic yogurt in inflammatory bowel disease patients显示文摘 | Lorea Baroja M Kirjavainen PV Hekmat S | | 0，，03： | 1 |
| 19 | A Case Report of Desmoid Tumor of the Finger显示文摘 | Berthe JV Lorea P De Prez C | 2003 | Chir Main2003，22，6： | 1 |
| 20 | Clinical and experimental approaches to the pathophysiology of interleukin-18 in cancer progression显示文摘 | Fernando Vidal-Vanaclocha Lorea Mendoza Naiara Telleria Clarisa Salado María Valcárcel Natalia Gallot Teresa Carrascal Eider Egilegor Jabier Beaskoetxea Charles A. Dinarello | 2006 | Cancer and Metastasis Reviews2006，，3： | 1 |
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