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| 1 | 高危患者目标血压与心血管病预后显示文摘指南推荐血压目标值应〈140/90 mmHg(1mmHg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。 | B?hm M Schumacher H Teo KK Lonn EM Mahfoud F Mann JF Mancia G Redon J Schmieder RE Sliwa K Weber MA Williams BYusuf S 曲浥晨 叶鹏 | 2017 | 中华高血压杂志2017，25，6： | 14 |
| 2 | Effect of ramipril and of rosiglitaznne on carotid intima-media thickness in people with impaired glucose tolerance or impaired fasting glucose: STARR (study of atheroselerosis with ramipril and rosiglitazone)显示文摘 | Lonn EM Gerstein HC Sheridan P | 2009 | J Am Coil Cardiol2009，53，22： | 1 |
| 3 | Effects of ramipril and vitamin E on atherosclerosis:the study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E(SECURE) 显示文摘 | Lonn EM Dphil SYM Dzavik V | 2001 | Circulation2001，103，： | 1 |
| 4 | The Study to Evaluate Carotid Ultrasound Changes in Patients Treated With Ramipril and Vitamin E (SECURE) 显示文摘 | Lonn EM Yusuf S Dzavik V Effects of ramipril and vitamin E on atherosclerosis | 2001 | Circulation2001，103，： | 1 |
| 5 | Effect of ramipril and of rosiglitazone on carotid intima-media thickness in people with impaired glucose tolerance or impaired fasting glucose: STARR (STudy of Atherosclerusis with Ramipril and Rosiglitazone) 显示文摘 | Lonn EM Gerstein HC Sheridan P | 2009 | J Am Coll Cardiol2009，53，22： | 1 |
| 6 | Emerging role of angiotensin converting enzyme inhibitors in cardiac and vascular protection 显示文摘 | Yusuf S Jhap U | 1994 | Circulation1994，90，： | 1 |
| 7 | Blood-pressure lowering in intermediate-risk persons without cardiovascular dis- ease显示文摘 | Lonn EM Bosch G L6pez-Jaramillo P | 2016 | New Engl J Med2016，374，21： | 1 |
| 8 | Effect of ramipril and of rosiglitazone on carotid intima - media thickness in peo- ple with impaired glucose tolerance or impaired fasting glucose: STARR (Study of Atherosclerosis with Ramipril and Rosiglita- zone)显示文摘 | Lonn EM Gerstein HC Sheridan P | 2009 | J Am CoU Cardiol2009，53，22： | 1 |
| 9 | Effects of vitamin E on cardiovascular outcomes in people with mild-to-moderate renal insufficiency:results of the HOPE study显示文摘 | Mann JF Lonn EM Yi Q | 2004 | Kidney Int2004，65，4： | 1 |
| 10 | 显示文摘 | Dzavik V Yusuf S | 1999 | Circulation1999，100，： | 1 |
| 11 | Heart rate is associated with increased risk of major cardiovascular events,cardiovascular and all-cause death in patients with stable chronic cardiovascular disease:an analysis of ONTARGET/TRANSCEND显示文摘 | Lonn EM Rambihar S Gao P | 2014 | Clin Res Cardiol2014，103，2： | 1 |
| 12 | Effects of vitamin E on cardiovascular outcomes in people with mild-to-moderate renal insufficiency: results of the HOPE study显示文摘 | Mann JF Lonn EM Yi Q | 2004 | Kidney Int2004，65，： | 1 |
| 13 | Effects of vitamin E on cardiovascular outcomes in people with mild-to-moderate re- nal insufficiency: results of the HOPE study ]显示文摘 | Mann JF Lonn EM Yi Q | 2004 | Kidney Int2004，65，4： | 1 |
| 14 | 每周1次胰高血糖素样肽1受体激动剂dulaglutide注射对2型糖尿病患者动态血压和心率的作用显示文摘已知治疗2型糖尿病的胰高血糖素样肽1受体激动剂与收缩压轻度降低及心率增加有关。但基于临床测定的结果不能充分评估一种药物的24h药代动力学作用。该研究采用动态血压监测评估每周一次胰高血糖素样肽1受体激动剂dulaglutide对血压和心率的作用。方法:纳入755例[年龄(56±10)岁,81%为白人,48%为女性]服用口服降糖药≥1种,诊室血压为90-140/60-90mm Hg(1mm Hg=0.133kPa)之间的2型糖尿病患者随机接受dulaglutide(1.5或0.75mg)或安慰剂皮下注射26周。在基线,4、16、26周时监测动态血压。主要观察指标为从基线到16周时24h平均收缩压的改变, | 赵狄 叶鹏 Ferdinand KC White WB Calhoun DA Lonn EM Sager PT Brunelle R Jiang HH Threlkeld RJ Robertson KE Geiger MJ | 2014 | 中华高血压杂志2014，22，8： | 1 |
| 15 | Study design and baseline characteristics of the study to evaluate carotid ultrasound changes in patients treated with tamipril and vitamin E: Secure显示文摘 | Lonn EM Yusuf S Doris CI | 1996 | Am J Cardiol1996，78，8： | 1 |
| 16 | 胃肠道出血、血管发育异常、心血管疾病和获得性血管性血友病综合征显示文摘任何确定的止血障碍都有其典型的特定临床表现.比如,严重的血小板减少会产生皮肤粘膜出血(瘀斑、鼻出血、月经过多).典型性血友病(先天性缺乏Ⅷ因子或Ⅸ因子)表现为关节或肌肉的出血.我们认为,血管性血友病因子(vWF)中的大分子量(HMW)多聚体的细微缺失--称为血管性血友病综合征-2A型(VWS-2A)-临床表现为黏膜下层血管异常所致的胃肠道(GI)的出血,即血管发育异常.因为是解剖学意义上的出血,所以不能说明其与止血障碍的潜在关系.我们对该问题的讨论主要是围绕着主动脉狭窄与出血性胃肠道血管发育异常之间的关联,特别是以VWS-2A解释这种关联,以及置换狭窄性瓣膜术治疗出血性血管发育异常效果显著这一事实.我们的观点是未被研究透彻的VWS-2A能够解释许多老年病人的出血性GI血管发育异常,特别是由除严重主动脉狭窄外的心血管疾病引起的VWS-2A. | Warkentin TE Moore JC Anand SS Lonn EM Morgan DG 陈峰 | 2004 | 国外医学(输血及血液学分册)2004，27，3： | 0 |
| 17 | 颈动脉内膜中层厚度测量未改善高血压患者心血管风险预测显示文摘颈动脉内膜中层厚度(carotid intima-media thickness,CIMT)是心血管风险的标志。目前仍不清楚颈总动脉CIMT测量能否改善高血压患者10年内首发心肌梗死或脑卒中的风险预测。研究人员获取正在进行的大规模荟萃分析:USE-IMT研究中的高血压参与者(收缩压≥140和舒张压≥90 mm Hg,1mm Hg=0.133kPa)数据进行分析。 | Bots ML Groenewegen KA erson TJ Britton AR Dekker JM Engstrm G Evans GW de Graaf J Grobbee DE Hedblad B Hofman A Holewijn S Ikeda A Kavousi M Kitagawa K Kitamura A Ikram MA Lonn EM Lorenz MW Mathiesen EB Nijpels G Okazaki S O'Leary DH Polak JF Price JF Robertson C Rembold CM Rosvall M Rundek T Salonen JT Sitzer M Stehouwer CD Franco OH Peters SA den Ruijter HM 赵狄 | 2014 | 中华高血压杂志2014，22，6： | 0 |
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