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| 1 | Utility of magnetic resonance imaging in anorectal disease显示文摘Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily. CT scanning and endorectal ultrasound have become popular in assessment of anatomy and staging of tumors, but have limitations. Magnetic resonance imaging (MRI) has the capability to fill in the gaps left open by more conventional imaging modalities and continues to be promising as the definitive imaging technique in the pelvis, especially with advancement of emerging technologies in this field. A comprehensive review of this topic has been undertaken. Anorectal disease is divided into three broad categories: cancer, fistula/abscess, and pelvic floor disorders. A review of the literature is performed to evaluate the use of MRI and other imaging modalities in these three areas. Preoperative imaging is useful in the evaluation of all three areas of anorectal disease. MRI is an effective tool in delineating anatomy and, when correlating with the specific clinical scenario, is an effective adjunct in clinical decision-making in order to optimize outcome. MRI continues to be a promising and novel approach to imaging various afflictions of the anorectum and the pelvic floor. Its role is more well-established in some areas than in others, and there are still signif icant limitations. As technology advances, MRI will shed more light on a complex anatomical area. | Loren Berman Gary M Israel Shirley M McCarthy Jeffrey C Weinreb Walter E Longo | 2007 | World Journal of Gastroenterology2007，13，23： | 11 |
| 2 | 36例小细胞骨肉瘤的临床病理学、免疫组化及分子分析显示文摘Righi A,Gambarotti M,Longo S,et al. Sma11 ce11 osteosarco-ma:c1inicopatho1ogic,immunohistochemica1,and mo1ecu1ar a-na1ysis of 36 cases. Am J Surg Patho1,2015,39(5):691-9.小细胞骨肉瘤是骨肉瘤的一种非常罕见亚型,组织学类似骨的其它小细胞恶性肿瘤,特别是尤因肉瘤。为鉴别小细胞骨肉瘤及骨的其他原发性小细胞恶性肿瘤,作者对36例原发性骨的小细胞骨肉瘤进行CD99和SATB2(一种成骨细胞分化标志物)的免疫组化(IHC)表达情况评估。并通过荧光原位杂交和(或)逆转录聚合酶链反应( RT-PCR)分析了EWSR1和FUS 基因突变情况,进一步评估小细胞骨肉瘤和尤因肉瘤是否有相同的遗传性学改变。 | Righi A Gambarotti M Longo S 魏建国 许春伟 邰艳红 | 2015 | 临床与实验病理学杂志2015，31，6： | 5 |
| 3 | Hepatocellular carcinoma staging systems: Hong Kong liver cancer vs Barcelona clinic liver cancer in a Western population显示文摘BACKGROUND Despite being the world’s most widely used system for staging and therapeutic guidance in hepatocellular carcinoma(HCC)treatment,the Barcelona clinic liver cancer(BCLC)system has limitations,especially regarding intermediate-grade(BCLC-B)tumors.The recently proposed Hong Kong liver cancer(HKLC)staging system appears useful but requires validation in Western populations.AIM To evaluate the agreement between BCLC and HKLC staging on the management of HCC in a Western population,estimating the overall patient survival.METHODS This was a retrospective study of HCC patients treated at a university hospital in southern Brazil between 2011 and 2016.Demographic,clinical,and laboratory data were collected.HCC staging was carried out according to the HKLC and BCLC systems to assess treatment agreement.Overall survival was estimated based on the treatment proposed in each system.RESULTS A total of 519 HCC patients were assessed.Of these,178(34.3%)were HKLC-I;95(18.3%)HKLC-IIA;47(9.1%)HKLC-IIB;29(5.6%)HKLC-IIIA;30(5.8%)HKLCIIIB;75(14.4%)HKLC-IV;and 65(12.5%)HKLC-V.According to the BCLC,25(4.9%)were BCLC-0;246(47.4%)BCLC-A;107(20.6%)BCLC-B;76(14.6%)BCLCC;and 65(12.5%)BCLC-D.The general agreement between the two systems was 80.0%-BCLC-0 and HKLC-I(100%);BCLC-A and HKLC-I/HKLC-II(96.7%);BCLC-B and HKLC-III(46.7%);BCLC-C and HKLC-IV(98.7%);BCLC-D and HKLC-V(41.5%).When sub-classifying BCLC-A,HKLC-IIB,HKLC-IIIA and HKLC-IIIB stages according to the up-to-7 in/out criterion,13.4,66.0,100 and 36.7%,respectively,of the cases were classified as up-to-7 out.CONCLUSION In a Western population,the general agreement between the two systems was 80.0%,although in BCLC-B cases the agreement was low,suggesting that some individuals could be candidates for the curative treatment recommended by the HKLC.The authors suggest that the BCLC system should be routinely employed,although for BCLC-B cases it should be associated with the HKLC system. | Laura Bainy Rodrigues de Freitas Larisse Longo Deivid Santos Ivana Grivicich Mário Reis Alvares-da-Silva | 2019 | World Journal of Hepatology2019，11，9： | 3 |
| 4 | Serum tumor markers CEA,CYFRA21-1,and CA-125 are associated with worse prognosis in advanced non-small-cell lung cancer (NSCLC)显示文摘 | Cedrés S Nu?ez I Longo M | | 0，，03： | 2 |
| 5 | Acute surgical emergencies in inflammatory bowel disease显示文摘 | Dale F Berg Anil M Bahadursingh Donald L Kaminski Walter E Longo | 2002 | The American Journal of Surgery2002，，： | 2 |
| 6 | Experimental and theoretical study of the ferroelectric and piezoelectric behavior of strontium-doped PZT显示文摘 | NASAR R S CERQUEIRA M LONGO E | 1999 | J Mater Sci1999，34，： | 2 |
| 7 | Helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpura显示文摘 | Emilia G Longo G Luppi M | 2001 | Blood2001，97，3： | 1 |
| 8 | The pathologic and clinical heterogeneity of lymphocyte-depleted Hodgkin's disease显示文摘 | Kant J A Hubbard S M Longo D L | 1986 | J Clin Oncol1986，4，3： | 1 |
| 9 | Pharmacokinetics of a new heat-treated concentrate of factor Ⅷ estimated by model-independent methods显示文摘 | Longo G Malucci M Messori Andrea | 1986 | Thromb Res1986，42，4： | 1 |
| 10 | An experimentally derived ki- netic model for smectite-to-illite conversion and its use as a geother- mometer 显示文摘 | Huang W L Longo J M Pevear D R | 1993 | Clays and Clay Minerals1993，41，2： | 1 |
| 11 | Freezing of gait andexecutive functions in patients with Parkinson's disease显示文摘 | Amboni M Cozzolino A Longo K | 2008 | MovDisord2008，23，3： | 1 |
| 12 | Minimally invasive locked plating of distal tibia fractures is safe and effective显示文摘 | Ronga M Longo UG Maffulli N | | 0，，04： | 1 |
| 13 | Treatment of experimental periodont- itis in rats using repeated adjunctive anti- microbial photodynamic therapy显示文摘 | Garcia VG Longo M Femandes LA | 2013 | Las- ers in medical science2013，28，1： | 1 |
| 14 | Minimally invasive osteosynthesis of distal tibial fractures using locking plates 显示文摘 | Ronga M Shanmugam C Longo UG | 2009 | Orthop Clin North Am2009，40，： | 1 |
| 15 | Pharmacological res- cue of caruitine transport in primary earnitine deficiency 显示文摘 | Di san Filippo CA Pasquali M Longo N | 2006 | Hum Mutat2006，27，： | 1 |
| 16 | Management of less common tumors of the colon, rectum, and antis 显示文摘 | Cuffy M Abir F Longo WE | 2006 | Clin Colorectal Cancer2006，5，： | 1 |
| 17 | Chemical dehumidification by liquid desiccants:theory and experiment显示文摘 | Lazzarin R M Gasparella A Longo G A | 1999 | International Journal of Refrigeration1999，22，： | 1 |
| 18 | Neoadjuvant intraarterial chemotherapy in nfiammatory carcinoma of the breast 显示文摘 | Bilbao J I Rebollo J Longo J M | 1992 | Brit J Radiol1992，65，2： | 1 |
| 19 | Defining cerebral palsy: pathogenesis, pathophysiology and new intervention 显示文摘 | Longo M Hankins GD | 2009 | Minerva Ginecologica2009，61，5： | 1 |
| 20 | Polymeric precursor method to the synthesis of XWO4(X = Ca and Sr)thin films-structural,micro-structural and spectroscopic investigations显示文摘 | Pontes F M Galhiane M S Santos L S Petit L A Kataoka F P Mabuchi G H Longo E Zampieri M Pi-zani P S | 2009 | Journal of Alloys and Compounds2009，477，12： | 1 |
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