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4篇 您的检索式:作者名="Linling Zheng"
    题名 作者 年代 出处 被引量
1Surfactant mediated HCB dechlorination in contaminated soils and sediments by micro and nanoscale Cu/Fe Particles显示文摘Songhu Yuan Zhonghua Zheng Xiang-Zhou Meng Jing Chen Linling Wang 2010Geoderma2010,,1:1
2Head-to-tail cyclization of a heptapeptide eliminates its cytotoxicity and significantly increases its inhibition effect on amyloid β-protein fibrillation and cytotoxicity显示文摘淀粉 --(A) 蛋白质聚集是 Alzheimers 疾病(广告) 的主要特点。纤维性颤动的抑制因此是广告的预防和处理的一条有希望的治疗学的途径。最近,我们设计了一个 heptapeptide 禁止者, LVFFARK (LK7 ) 。LK7 在纤维性颤动上显示出一个有希望的禁止的能力,但是对敏感自我装配并且显示高 cytotoxicity,它将妨碍它的实际申请。此处,我们由 head-to-tail 环合修改了 LK7 并且获得了周期的 LK7 (cLK7 ) 。cLK7 展览一不同自己组装从 LK7 的行为,并且比 LK7 和小 cytotoxicity 对解朊作用有更高的稳定性到 SHSY5Y 房间。热力学的分析表明 LK7 和 cLK7 能由静电的相互作用,氢结合和恐水病的相互作用绑在40,但是为40的 cLK7 的有约束力的亲密关系( K D = 4.96 mol/L )比 LK7 的高六倍( K D = 32.2 mol/L )。强壮的绑定使 cLK7 能稳定 40 的第二等的结构并且 potently 在广泛的集中范围禁止它的成核,纤维性颤动和 cytotoxicity,而 LK7 能仅仅中等在低集中禁止 A40 纤维性颤动和 cytotoxicity。调查结果显示肽环合是一条有希望的途径提高基于肽的淀粉的禁止者的表演。Shuai Ma Huan Zhang Xiaoyan Dong Linling Yu Jie Zheng Yan Sun 2018Frontiers of Chemical Science and Engineering2018,12,2:1
3Sensitive semi-quantitative detection of respiratory syncytial virus by dark-field light scattering imaging of the infected host cells显示文摘A novel sensitive semi-quantitative virus detection technique was developed using the respiratory syncytial virus(RSV) as an example, through dark-field light scattering imaging of the surface state of the virusinvaded host cells. In this method, anti-RSV-antibody modified gold nanoparticles(Au NPs) could bind with the invading virus on the cell membrane of the infected host cells through the specific antibody-antigen binding. Then,the host cells could be imaged by the localized surface plasmon resonance light scattering properties of Au NPs under a dark-field light scattering microscopy, which could be further used to semi-quantify the invading virus.Shujun Zhen Xiaoyan Wan Linling Zheng Chunmei Li Chengzhi Huang 2016Science Bulletin2016,61,8:1
4Isolation and Identification of Pathogenic Fungi Causing Decayin Luotian Chestnut during Late Storage Period and Research on Pathogenicity显示文摘In order to explore moldy mechanism of chestnut from Luotian County in storage process,the strains of pathogenic fungi were isolated from chestnuts after storage at room temperature for 70d.Six genera of fungi were found in chestnut through experimental identification,which were Ozoniumsp.,Fusarium sp.,Aspergillus sp.,Penicilliumsp.,Rhiopus sp.and Stachybotrys sp.,respectively.The re-inoculation tests had been conducted on pathogenic fungi whose isolating rate was greater than 10%.The result showed that the rest genera of fungi generally had no pathogenicity except Penicilliumsp.could infect non-injured chestnut with a lower moldy rate and lighter symptoms;but the moldy rate of strains was above 60% in injured inoculation and they showed heavy symptoms,among which the moldy rate of Ozoniumsp.and Aspergillus sp.were higher than 80%.The experimental results showed that injured chestnut were more likely to decay.Ozoniumsp.and Aspergillus sp.were important pathogenic fungi causing decay during storage process of chestnut.Li Linling Li Zheng Hua Juan Cheng Hua Liao Zhiqin Cheng Shuiyuan Tang Qing 2013Plant Diseases and Pests2013,4,6:0
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