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4篇 您的检索式:作者名="Lingqi Meng"
    题名 作者 年代 出处 被引量
1Chan teaching and learning: an aesthetic analysis of its educational import显示文摘Lingqi Meng P. Bruce Uhrmacher 2014Asia Pacific Education Review2014,,2:1
2Timing and Single-pulse Study of Pulsar J1909+0122 Discovered by CRAFTS显示文摘We report the discovery of PSR J1909+0122 by the Five-hundred-meter Aperture Spherical Radio Telescope(FAST)as part of the Commensal Radio Astronomy FAST Survey.PSR J1909+0122 has a spin period of 1.257 s and a dispersion measure of 186.2 pc cm^(-3).The averaged pulse profile shows two distinct components.We performed a single-pulse study based on a one-hour observation at 1.25 GHz on 2021 August 23.We used a threshold of 5σ_(ep) to measure the nulling fraction(NF)as 63%±1.5%.The longitude-resolved fluctuation spectra and fast Fourier transform spectra of the binary sequences revealed the quasi-periodicity of nulling with a period of 30 rotation periods.We examined the reliability of the periodicity by comparing it to random noise injection.The NF,E,and modulation periodicity P_(M) of PSR J1909+0122 were compared with other periodic nulling pulsars,showing that the source of J1909+0122 has the second largest NF in the population.Long-term timing observations over six months were used to derive the phase-connected ephemeris of this pulsar.The measured P and P values disfavor dipolar geometry for polar gap models,and the prediction for a space-charge-limited flow model in the case of inverse Compton scattering is only just above the death line.In this work,PSR J1909+0122 has revealed possible correlations between nulling behavior and pulsar properties,which will help to shed light on the pulsar emission mechanism and its temporal evolution in future observations.Yutong Chen Pei Wang Di Li Erbil Gügercinoğlu Rushuang Zhao Lingqi Meng Jianping Yuan Jiarui Niu Weiwei Zhu Yi Feng Chenchen Miao Chenhui Niu Qingdong Wu Na Wang Shen Wang Xiaoyao Xie Mengyao Xue Jumei Yao Mao Yuan Shanping You Xuhong Yu Youling Yue Jie Zhang Junshuo Zhang Lei Zhang Yabiao Wang Zhenye Gan Yuxi Li Zhongyi Sun Chengjie Wang 2023Research in Astronomy and Astrophysics2023,23,8:0
3Advance in Research on Anti-tumor Pharmacological Mechanism of Cryptotanshinone显示文摘Cryptotanshinone is a natural active ingredient extracted from traditional Chinese medicine Radix Salviae Miltiorrhizae.It has a variety of pharmacological effects,in addition to preventing and treating ischemic diseases,coronary artery disease Alzheimer's disease and fighting tumors.The anti-tumor effects are exerted through inhibiting tumor cell proliferation,inducing tumor cell apoptosis,inhibiting tumor metastasis and invasion,inhibiting angiogenesis and regulating reactive oxygen species levels.The studies on the anti-tumor activity and action mechanism of cryptotanshinone in recent years are reviewed in this article.Jiaru WANG Lingqi MENG Yi ZHANG Hao WANG Wanting XU Yang LIU Yu ZHANG Tong ZHANG Shinong WANG Yuqing ZHAI Yinghua LUO Chenghao JIN 2018Medicinal Plant2018,9,6:0
4Apoptotic Effect of Cryptotanshinone on Human Melanoma A375 Cells显示文摘[Objectives] The aim was to investigate the effect of cryptotanshinone on apoptosis of human melanoma A375 cells and its related mechanism of mitochondrial pathway.[Methods]The cytotoxic effect of cryptotanshinone on apoptosis of human melanoma A375 cells was detected by MTT colorimetry.The apoptosis of melanoma A375 cells was detected with Annexin V-FITC/PI and observed by fluorescence inverted microscope.The expression of apoptosis-related proteins was detected by Western blotting.[Results]The viability of the A375 cells decreased with the increase of drug concentration.The fluorescence intensity of the cells increased with the treatment time.The expression of pro-apoptotic protein caspase-3 gradually increased,while the expression of apoptosis-inhibiting proteins p-AKT and Bcl-2 gradually reduced.[Conclusions]Cryptotanshinone induces apoptosis of human melanoma A375 cells via AKT signaling pathway,thus exerting a good cytotoxic effect on A375 cells.Jinqian LI Jiaru WANG Lingqi MENG Yi ZHANG Hao WANG Wanting XU Yang LIU Yu ZHANG Shinong WANG Yuqing ZHAI Yinghua LUO Chenghao JIN 2018Medicinal Plant2018,9,6:0
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