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| 1 | Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells显示文摘有各种各样的长度的 telomeres 的返老还童在导致的 pluripotent 干细胞(iPSCs ) 被发现了。telomere 长度规定的机制在 iPSCs 的正式就职和增长期间留下逃犯。我们证明 telomere 动力学在 reprogramming 和经过期间在鼠标 iPSCs 是可变的,并且建议这些差别多半源于多重潜在的因素,包括包括外长的 reprogramming 因素的表示的 telomerase 机械, telomerase 独立的机制和同种细胞的影响。用一个基因模型 telomerase 缺乏(为 iPSCs 的推导和段落的 Terc −/− 和 Terc +/−) 房间,我们发现 telomerase 在 iPSCs 的 reprogramming 和自强起一个关键作用。进一步,当由再结合的延伸和维护的其他的小径也被要求时, telomeres 的 telomerase 维护为真 pluripotency 的正式就职是必要的,然而并非足够。一起, telomere 生物学的几个方面可以在 iPSCs 说明可变 telomere 动力学。尤其是,采用在 iPSC reprogramming 期间维持 telomeres 的机制很类似于胚胎的干细胞的那些。这些调查结果可以也联系到这些机制能为在由体的房间的原子 reprogramming 以后的 telomere 异质负责的克隆的地原子转移。 | Fang Wang Yu Yin Xiaoying Ye Kai Liu Haiying Zhu Lingling Wang Maria Chiourea Maja Okuka Guangzhen Ji Jiameng Dan Bingfeng Zuo Minshu Li Qian Zhang Na Liu Lingyi Chen Xinghua Pan Sarantis Gagos David L Keefe Lin Liu | 2012 | Cell Research2012，22，4： | 7 |
| 2 | Effects of transglutaminase on the rheological and mixolab thermomeehanieal characteristics of oat dough 显示文摘 | Weining H Lingling L Feng W | 2010 | Food Chemistry2010，121，： | 1 |
| 3 | Cellular concentrations and uniformity of cell-type accumulation of two LEA proteins in cotton embryos显示文摘 | Roberts J K Desimone N A Lingle W L | 1993 | Plant Cell1993，5，7： | 1 |
| 4 | Cellular concentrations and uniformity of cell-type accumulation of two lea proteins in cotton embryos显示文摘 | ROBERTS J K DESIMONE N A LINGLE W L | 1993 | The Plant Cell Online1993，5，7： | 1 |
| 5 | Centrosome amplification and the development of cancer显示文摘 | D'Assoro A B Lingle W L Salisbury J L | 2002 | Oncogene2002，21，40： | 1 |
| 6 | Modeling of DFIG-based wind farms for SSR analysis显示文摘 | Lingling F Kavasseri R Zhixin L M | 2010 | IEEE Trans on Power Delivery2010，25，4： | 1 |
| 7 | Construction of [Cu_nI_n]-based coordination polymers via flexible benzimidazolyl-based ligands显示文摘Four new [CunIn]-based coordination polymers, [{Cu4(μ3-I)4(mbbm)2}·2DMF]n (1), [(CuI)2(mbbm)2]n (2), [{Cu2(μ-I)2-(ebbm)2}·2MeCN]n (3), and [Cu2(μ-I)2(prbbm)2]n (4), were prepared from solvothermal reactions of CuI with three flexible ligands [(bzim)(CH2)n(bzim)] (bzim = benzimidazole; n = 1, mbbm; n = 2, ebbm; n = 3, prbbm). These compounds were characterized by elemental analysis, IR and X-ray crystallography. 1 consists of cubanelike [Cu4(μ3-I)4] fragments that link the neighboring ones via mbbm bridges to form a 1D ladder-type chain. 2 contains mononuclear [CuI] fragments that are bridged by mbbm ligands to yield a 1D zigzag chain. 3 or 4 contains a [Cu2(μ-I)2] dimeric fragment, which works as a four-connecting node to link its four equivalent ones to form a 2D (4,4) network (3) or acts as a two-connecting node to connect its two equivalent ones via two pairs of prbbm bridges to form a 1D double chain (4). The photoluminescent properties of 1-4 in the solid state at ambient temperature were investigated. | LI LingLing, REN ZhiGang, Lü Xue, WANG HeMing, CHANG YuJie, LI HongXi, WU Bing & LANG JianPing College of Chemistry, Chemical Engineering and Materials Science, Suzhou University, Suzhou 215123, China | 2010 | Science China Chemistry2010，53，10： | 1 |
| 8 | Nonparaxial Lorentz and Lorentz-Gauss beams显示文摘 | Yu Hong Xiong Lingling Lü Baida | 2010 | Optik2010，，： | 1 |
| 9 | Aurora A, centrosome structure, and the centrosome cycle 显示文摘 | Lukasiewicz K B Lingle W L | 2009 | Environ Mol Mutagen2009，50，8： | 1 |
| 10 | Centrosomes and cancer显示文摘 | Salisbury J L Whitehead C M Lingle W L | 1999 | Biol Cell1999，91，： | 1 |
| 11 | Cellular concentrations and uniformity of cell-type accumulation of two Lea proteins in cotton embryos显示文摘 | Desimone N A Lingle W L | 1993 | Plant Cell1993，5，： | 1 |
| 12 | Modeling of DFIG-Based Wind Farms for SSR Analysis显示文摘 | Lingling F Kavasseri R Zhixin L M | 2010 | IEEE Trans on Power Delivery2010，25，4： | 1 |
| 13 | IL-23 promotes tumour incidence and growth显示文摘 | John L Langowski Xueqing Zhang Lingling Wu | 2006 | Nature2006，442，： | 1 |
| 14 | Lignocellulolysis by ascomycetes (Fungi) of a saltmarsh grass (smooth cordgrass)显示文摘 | NEWELL S Y PORTER D LINGLE W L | 1996 | Microscopy Research Technique1996，33，： | 1 |
| 15 | Modeling of DFIG-based wind farms for SSR analysis显示文摘 | Fan Lingling Kavasseri R Zhixin L M | 2010 | IEEE Transactions on Power Delivery2010，25，4： | 1 |
| 16 | The role of the centrosome in the development of malignant tumors 显示文摘 | LINGLE W L SALISBURY J L | 2000 | Curr Top Dev Biol2000，49，： | 1 |
| 17 | Intelligent Collision Avoidance by Fuzzy Logic Control显示文摘 | CHIAHAN L LINGLING W | 1997 | Robotics and Autonomous Systems1997，，20： | 1 |
| 18 | Soil salinity effects on crop growth and yield-Illustration of an analysis and mapping methodology for sugarcane显示文摘 | Wiegand C L Anderson G L Lingle S E | 1996 | Journal of Plant Physiology1996，148，： | 1 |
| 19 | Centrosome Amplification Drives Chromosomal Instability in Breast Tumor Development显示文摘 | Lingle W L Barrett S L Negron V C | 2002 | Proc Natl Acad Sci U S A2002，99，4： | 1 |
| 20 | Centrosome Amplification and The Development of Cancer显示文摘 | D'Assoro A B Lingle W L Salisbury L | 2002 | Oncogene2002，21，： | 1 |
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