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| 1 | Report on Childhood Obesity in China (9): Sugar-sweetened Beverages Consumption and Obesity显示文摘Objective To explore the associations between sugar-sweetened beverage (SSB) consumption and obesity as well as obesity-related cardiometabolic disorders among children in China. Methods A total of 6974 (boys 3558, girls 3412) children aged 6-13 years participated in the study. Each participant's height, weight, waist circumference, fasting glucose, triglycerides, total cholesterol, high- density lipoprotein cholesterol, and low-density lipoprotein cholesterol were measured. The type of beverage consumption was determined using a self-administered questionnaire. Results SSBs were consumed regularly by 46.1% of the children. The prevalence [adjusted odds ratio (95% confidence internal (CI)] of obesity was 7.6% [as the reference group (ref.)], 10.1% [1.36(1.07, 1.74)], and 11.6% [1.46(1.21, 1.75)], among children who regularly drank milk, other beverages and SSBs, respectively. Regularly drinking SSBs elevated the likelihood of abdominal obesity [adjusted odds ratio (95% CI): 1.36 (1.17, 1.59)]. The prevalence [adjusted odds ratio (95% CI)] of obesity among children who regularly drank sports/caloric beverages, carbonated beverages, sweet tea, and plant protein beverages was 16.8% [2.00(1.31, 3.07)], 12.7% [1.52(1.23, 1.88)], 11.5% [1.52(1.18, 1.95)], and 10.4% [1.41(1.03, 1.94)], respectively, which was higher than that of regular milk drinkers [7.6 % (ref.)]. The prevalence [adjusted odds ratio (95% CI)] of abdominal obesity among children who regularly drank sweet tea, fruit/vegetable juices, and carbonated beverages was 17.7% [1.55(1.26, 1.90)], 16.2% [1.36(1.09, 1.70)], and 15.3% [1.24(1.03, 1.50)], respectively, which was much higher than that of regular milk drinkers [12.8% (ref.)]. Conclusions Regular SSB consumption was positively related to obesity and abdominal obesity. This relationship should be investigated further using a longitudinal study design. | SHANG Xian Wen LIU Ai Ling ZHANG Qian HU Xiao Qi DU Song Ming MA Jun XU Gui Fa LI Ying GUO Hong Wei DU Lin LI Ting Yu MA Guan Sheng | 2012 | Biomedical and Environmental Sciences2012，25，2： | 23 |
| 2 | Report on Childhood Obesity in China (10): Association of Sleep Duration with Obesity显示文摘Objectives To explore the association of sleep duration with obesity among children in urban areas of China.Methods A total of 6 576 children(3 293 boys and 3 283 girls) aged 7-11 years were randomly selected from 36 primary schools in 6 metropolitan cities in China.A 7-day Physical Activity Recall was used to assess the sleep duration and physical activity level.The height,weight,waist circumference(WC) and percentage of body fat(%BF,as determined by bioelectrical impedance analysis technique) were measured by following the standardized operation procedures.The information on demography,lifestyle and eating habits was collected with a self-administered questionnaire from participants and their parents.Results The average sleep duration per night in the children was 9.7 h with the decreasing trends along with the increase of age(P<0.05).The sleep duration was negatively associated with body mass index(BMI) and WC in both boys and girls after adjustment for confounders(β value-0.23 and-0.82 for boys,-0.24 and-0.91 for girls,respectively,P<0.01).However,no significant association of sleep duration with %BF was found.Children who slept less than 9.0 h per night had a higher risk for overweight and obesity(OR=1.29,95% CI:1.01,1.64) and abdominal obesity(OR=1.38,95% CI:1.04,1.83) as compared with those who slept for 10.0-10.9 h.Conclusions Short sleep duration is associated with obesity.It is important to ensure adequate sleep duration of children and foster their healthy lifestyle at an early stage of life. | MENG Li Ping LIUAi Ling HU Xiao Qi ZHANG Qian DU Song Ming FANG Hong Yun MA Jun XU Gui Fa LI Ying GUO Hong Wei DU Lin MA Guan Sheng | 2012 | Biomedical and Environmental Sciences2012，25，2： | 16 |
| 3 | The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population显示文摘导致噪音的听觉损失(NIHL ) 是在环境、基因的因素之间的相互作用引起的复杂疾病。这研究调查了在 protocadherin 的基因可变性是否联系了 15 (PCDH15 ) 在一张中国人口位于增加的危险性下面到 NIHL 的发展。结果证明与 rs11004085 的 TT 遗传型相比, CT/CC 遗传型与 NIHL 的增加的风险被联系[调整机会比率(或)= 2.64;95% 信心间隔(CI ) :1.14-6.11, P = 0.024 ] 。另外,在 rs11004085 和 rs978842 之间的重要相互作用基因变化和噪音暴露在高级暴露组被观察(P < 0.05 ) 。而且,当与噪音暴露的高水平结合了时,风险 haplotype TAGCC 被观察(P < 0.05 ) 。因此,我们的学习证实在 PCDH15 的基因变化在人修改危险性到 NIHL 开发。 | XU Xiang Rong WANG Jing Jing YANG Qiu Yue JIAO Jie HE Li Hua YU Shan Fa GU Gui Zhen CHEN Guo Shun ZHOU Wen Hui WU Hui LI Yan Hong ZHANG Huan Ling ZHANG Zeng Rui JIN Xian Ning | 2017 | Biomedical and Environmental Sciences2017，30，2： | 9 |
| 4 | Polyoxypregnanes from the stems of Marsdenia tenacissima显示文摘From the stems of Marsdenia tenacissima two new polyoxypregnanes were isolated, their structures were elucidated by 1D, 2D- NMR as 11a,12b-di-O-tigloyl-tenacigenin B (1) and tenacigenoside E(2). | Qi Fa Li Xiao Ling Wang Li Sheng Ding Chang Zhang | 2007 | Chinese Chemical Letters2007，18，7： | 8 |
| 5 | Comparative genomic and transcriptomic analyses uncover the molecular basis of high nitrogen-use efficiency in the wheat cultivar Kenong 9204显示文摘Studying the regulatory mechanisms that drive nitrogen-use efficiency(NUE)in crops is important for sustainable agriculture and environmental protection.In this study,we generated a high-quality genome assembly for the high-NUE wheat cultivar Kenong 9204 and systematically analyzed genes related to nitrogen uptake and metabolism.By comparative analyses,we found that the high-affinity nitrate transporter gene family had expanded in Triticeae.Further studies showed that subsequent functional differentiation endowed the expanded family members with saline inducibility,providing a genetic basis for improving the adaptability of wheat to nitrogen deficiency in various habitats.To explore the genetic and molecular mechanisms of high NUE,we compared genomic and transcriptomic data from the high-NUE cultivar Kenong 9204(KN9204)and the low-NUE cultivar Jing 411 and quantified their nitrogen accumulation under high-and low-nitrogen conditions.Compared with Jing 411,KN9204 absorbed significantly more nitrogen at the reproductive stage after shooting and accumulated it in the shoots and seeds.Transcriptome data analysis revealed that nitrogen deficiency clearly suppressed the expression of genes related to cell division in the young spike of Jing 411,whereas this suppression of gene expression was much lower in KN9204.In addition,KN9204 maintained relatively high expression of NPF genes for a longer time than Jing 411 during seed maturity.Physiological and transcriptome data revealed that KN9204 was more tolerant of nitrogen deficiency than Jing 411,especially at the reproductive stage.The high NUE of KN9204 is an integrated effect controlled at different levels.Taken together,our data provide new insights into the molecular mechanisms of NUE and important gene resources for improving wheat cultivars with a higher NUE trait. | Xiaoli Shi Fa Cui Xinyin Han Yilin He Long Zhao Na Zhang Hao Zhang Haidong Zhu Zhexin Liu Bin Ma Shusong Zheng Wei Zhang Jiajia Liu Xiaoli Fan Yaoqi Si Shuiquan Tian Jianqing Niu Huilan Wu Xuemei Liu Zhuo Chen Deyuan Meng Xiaoyan Wang Liqiang Song Lijing Sun Jie Han Hui Zhao Jun Ji Zhiguo Wang Xiaoyu He Ruilin Li Xuebin Chi Chengzhi Liang Beifang Niu Jun Xiao Junming Li Hong-Qing Ling | 2022 | Molecular Plant2022，15，9： | 6 |
| 6 | VEGI-armed oncolytic adenovirus inhibits tumor neovascularization and directly induces mitochondria-mediated cancer cell apoptosis显示文摘脉管的 endothelial 细胞生长禁止者(VEGI ) 是肿瘤坏死因素总科的一个成员并且在脉管的动态平衡起一个重要作用。在这研究,调查 anticancer 这基因的治疗学的潜力, VEGI (VEGI-251 ) 的分泌 isoform 与 E1B 55 kDa 基因删除(ZD55 ) 被插入到有选择地复制的侵入人体气管粘膜的病菌构造 ZD55-VEGI-251。我们这里报导 potently 从 ZD55-VEGI-251-infected 癌症房间生产的分泌 VEGI-251 禁止 endothelial 房间增长,在在 vivo 的小鸡 chorioallantoic 膜的 vitro 和 angiogenesis 的试管形成。另外, ZD55-VEGI-251 感染在几根人的癌症房间线上比控制病毒导致更严重的 cytopathic 效果,包括颈的癌症房间线 HeLa, hepatoma 房间线 SMMC-7721 和 colorectal 癌症房间线 SW620。进一步的学习表明增加的 cytotoxicity 是 caspase-9 激活,提高的 caspase-3 激活和 PARP 劈开伴随的 VEGI-251 autocrine 依赖的、调停线粒体的 apoptosis 的结果。而且,显著地忍受颈的人和 colorectal 肿瘤异种皮移植的 athymic 裸体人老鼠的 ZD55-VEGI-251-treatment 压制了肿瘤生长。我们的调查结果显示 antiangiogenesis 和 apoptosis 感应的活动的联合效果为癌症使 VEGI-251-armed oncolytic 侵入人体气管粘膜的病菌成为一个有希望的治疗学的代理人。 | Tian Xiao Jun Kai Fan Hong Ling Huang Jin Fa Gu Lu-Yuan Li Xin Yuan Liu | 2010 | Cell Research2010，20，3： | 5 |
| 7 | Investigation on poly[(methylsilylene ethynylene phenylene ethynylene)-co-(tetramethyldisiloxane ethynylene phenylene ethynylene)]显示文摘Poly[(methylsilylene ethynylene phenylene ethynylene)-co-(tetramethyldisiloxane ethynylene phenylene ethynylene)] was synthesized by polycondensation reaction of m-diethynylbenzene magnesium reagent with 1,3-dichlorotetramethyldisiloxane and dichloromethylsilane. The copolymer was characterized by FT-IR, 1H NMR, differential scanning calorimetry and thermogravi-metric analysis. The results show that the copolymer exhibits good processability and cures at low temperatures. The cured copolymer shows high thermal stability. | Fei Gao Ling Ling Zhang Fa Rong Huang Lei Du | 2010 | Chinese Chemical Letters2010，21，6： | 3 |
| 8 | Automatic Identification of Clear-Air Echoes Based on Millimeter-wave Cloud Radar Measurements显示文摘Millimeter-wave cloud radar(MMCR)provides the capability of detecting the features of micro particles inside clouds and describing the internal microphysical structure of the clouds.Therefore,MMCR has been widely applied in cloud observations.However,due to the influence of non-meteorological factors such as insects,the cloud observations are often contaminated by non-meteorological echoes in the clear air,known as clear-air echoes.It is of great significance to automatically identify the clear-air echoes in order to extract effective meteorological information from the complex weather background.The characteristics of clear-air echoes are studied here by combining data from four devices:an MMCR,a laser-ceilometer,an L-band radiosonde,and an all-sky camera.In addition,a new algorithm,which includes feature extraction,feature selection,and classification,is proposed to achieve the automatic identification of clear-air echoes.The results show that the recognition algorithm is fairly satisfied in both simple and complex weather conditions.The recognition accuracy can reach up to 95.86%for the simple cases when cloud echoes and clear-air echoes are separate,and 88.38%for the complicated cases when low cloud echoes and clear-air echoes are mixed. | Ling YANG Yun WANG Zhongke WANG Qian YANG Xingang FAN Fa TAO Xiaoqiong ZHEN Zhipeng YANG | 2020 | Advances in Atmospheric Sciences2020，37，8： | 2 |
| 9 | LncRNA LUCAT1 Activation Mediated by theDown-regulation of DNMT1 Is Involved inCell Apoptosis Induced by PM2.5显示文摘Particulate matter (PM), which is a greatenvironmental concern, has been classified as aGroup 1 human carcinogen by the InternationalAgency for Research on Cancer (IARC).Epidemiological and experimental studies haveindicated that chronic exposure to PM, especiallyPM2.5 (particles with an aerodynamic diameter lessthan 2.5 μm) may lead to an increase in lung cancerincidence. | LING Xiao Xuan ZHANG Hai Qiao LIU Jia Xian LIU Zhi Dong PENG Jian Ming ZHANG Xiao Qing SHAO Jun Li CHEN Zhen Fa LIU Lin Hua | 2018 | Biomedical and Environmental Sciences2018，31，8： | 2 |
| 10 | Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China显示文摘 | Gui‐Rui Yu Xian‐Jin Zhu Yu‐Ling Fu Hong‐Lin He Qiu‐Feng Wang Xue‐Fa Wen Xuan‐Ran Li Lei‐Ming Zhang Li Zhang Wen Su Sheng‐Gong Li Xiao‐Min Sun Yi‐Ping Zhang Jun‐Hui Zhang Jun‐Hua Yan Hui‐Min Wang Guang‐Sheng Zhou Bing‐Rui Jia Wen‐Hua Xiang Ying‐Nian Li Lia | 2012 | Glob Change Biol2012，，3： | 1 |
| 11 | The effect of cerium ( Ⅱ ) on the chlorophyll formation in spinach显示文摘 | FA S H LING W XIANG X M ZHENG W GUI W Z | 2002 | BiologicalTrace Element Research2002，89，3： | 1 |
| 12 | Detection and characterization of viruses causing hand, foot and mouth disease from children in Seri Kembangan, Malaysia显示文摘 | Ling BP Jainian FA Harmal NS | 2014 | Trop Biomed2014，31，4： | 1 |
| 13 | Solid-phase photocatalytic degradation of polystyrene with modified nano-TiO2 catalyst显示文摘 | Zan Ling Wang Songlin Fa Wenjun | | 0，，24： | 1 |
| 14 | Protective effect of recombinant human somatotropin on amyloid betapeptide induced learning and memory deficits in mice显示文摘 | Ling FA Hui DZ Ji SM | 2007 | Growth Horm IGF Res2007，17，4： | 1 |
| 15 | Detection and characterization of viruses causing hand, foot and mouth disease from children in Seri Kemhangan, Malaysia 显示文摘 | Ling BP Jalilian FA Harmal NS | 2014 | Trop Biomed2014，31，4： | 1 |
| 16 | Solid-phase photocatalytic degradation of polystyrene with modified nano-TiO 2 catalyst显示文摘 | Ling Zan Songlin Wang Wenjun Fa Yanhe Hu Lihong Tian Kejian Deng | 2006 | Polymer2006，，24： | 1 |
| 17 | Acoustic Goos-H?nchen effect显示文摘We report two models of the lateral displacement of acoustic-wave scattering on a fluid-solid interface that reveal an acoustic analog of the Goos-H?nchen effect in optics. This acoustic analog is called the acoustic Goos-H?nchen effect. Using newly proposed models, we made numerical calculations for the system of a water-Perspex interface. Specifically, in the post-critical-angle region,we observed a lateral displacement(and transition time) of the reflected P-wave with respect to the incident P-wave. The first arrival of the acoustic signal from the interface is found to be a reflected P-wave rather than the sliding-refraction P-wave usually described in traditional acoustic-logging sliding P-wave theory. For both proposed models, the effective propagation speed of the reflected P-wave along the interface depends on not only the physical properties of the interfacial media but also the incident angle.These observations are intriguing and warrant further investigation. | Lin Fa Ling Xue YuXiao Fa YongLan Han YanDong Zhang HongShen Cheng PengFei Ding GuoHui Li ShaoJie Tang ChunLing Bai BingJie Xi XiaoLin Zhang MeiShan Zhao | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，10： | 1 |
| 18 | Arterial thrombo- embolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab 显示文摘 | Scappaticci FA Ski|lings JR Holden SN | 2007 | J Natl Cancer Inst2007，99，16： | 1 |
| 19 | Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China显示文摘 | Gui‐Rui Yu Xian‐Jin Zhu Yu‐Ling Fu Hong‐Lin He Qiu‐Feng Wang Xue‐Fa Wen Xuan‐Ran Li Lei‐Ming Zhang Li Zhang Wen Su Sheng‐Gong Li Xiao‐Min Sun Yi‐Ping Zhang Jun‐Hui Zhang Jun‐Hua Yan Hui‐Min Wang Guang‐Sheng Zhou Bing‐Rui Jia Wen‐Hua Xiang Ying‐Nian Li Lia | 2012 | Glob Change Biol2012，，3： | 1 |
| 20 | Photocatalysis effect of nanometer TiO2 and TiO2-coated ceramic plate on Hepatitis B virus显示文摘 | ZAN Ling FA Wenjun PENG Tianyou | 2007 | Journal of Photochemistry and Photobiology B:Biology2007，86，： | 1 |
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