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| 1 | The development of collagen based composite scaffolds for bone regeneration显示文摘Bone is consisted of bone matrix,cells and bioactive factors,and bone matrix is the combination of inorganic minerals and organic polymers.Type I collagen fibril made of five triple-helical collagen chains is the main organic polymer in bone matrix.It plays an important role in the bone formation and remodeling process.Moreover,collagen is one of the most commonly used scaffold materials for bone tissue engineering due to its excellent biocompatibility and biodegradability.However,the low mechanical strength and osteoinductivity of collagen limit its wider applications in bone regeneration field.By incorporating different biomaterials,the properties such as porosity,structural stability,osteoinductivity,osteogenicity of collagen matrixes can be largely improved.This review summarizes and categorizes different kinds of biomaterials including bioceramic,carbon and polymer materials used as components to fabricate collagen based composite scaffolds for bone regeneration.Moreover,the possible directions of future research and development in this field are also proposed. | Dawei Zhang Xiaowei Wu Jingdi Chen Kaili Lin | 2018 | Bioactive Materials2018，3，1： | 16 |
| 2 | Characteristics of authigenic pyrites in shallow core sediments in the Shenhu area of the northern South China Sea: Implications for a possible mud volcano environment显示文摘Distinct pyrites have been recovered from a shallow sediment core from Site 4B in the Shenhu area of the northern South China Sea. Based on the lithology, texture and structure of sediments, the stable sulfur isotope of pyrite and the total organic carbon (TOC) concentration of the sediments, a distinctive sediment interface is identified at a depth of about 1 m below the seafloor in the core sediments. The pyrites only accumulate in the lower part of the core as rods and foraminifera-infillings, and mainly within three intervals marked by high pyrite concentrations. The amount of pyrite in the sediments shows no remarkable correlation with TOC in the Site 4B core sediments. The stable sulfur isotopes of the pyrite have extremely negative values ranging from 41.69‰ to 49.16‰. They are considered to be the mutual product of sulfate bacterial reduction and sulfur bacterial disproportionation. Our research proposes that Site 4B might be located in or near a possible mud volcano sedimentary environment; a large amount of methane could migrate from deep to shallow sediments in an active mud volcano and thereby play a key role in the intensity of sulfate bacterial reduction and the amount of pyrite formed at Site 4B. Further, the variation in flux of deep methane fluid by intermittent mud volcanic eruptions might result in the deposition of authigenic pyrite intervals. | XIE Lei WANG JiaSheng WU NengYou WU DaiDai WANG Zhou ZHU XiaoWei HU Jun CHEN HongRen LIN Qi | 2013 | Science China Earth Sciences2013，56，4： | 14 |
| 3 | Downregulation of serum mi R-17 and mi R-106b levels in gastric cancer and benign gastric diseases显示文摘Altered micro RNA(mi RNA) associated with gastric cancer(GC) development and mi R-17 and mi R-106 b were differentially expressed in GC tissues. This study detected serum levels of mi R-17 and mi R-106 b expression in GC, benign gastric disease(BGD) and healthy controls to assess them as tumor markers for GC. Serum samples from 40 GC, 32 BGD(10 gastric ulcer, 14 gastric polyps, and 8 gastric ulcer with polyps) and 36 healthy individuals were subjected to quantitative reverse transcription polymerase chain reaction(q RT-PCR) analysis of mi R-17 and mi R-106 b expression. The data showed that the serum levels of mi R-17 and mi R-106 b were significantly reduced in healthy individuals and BGD patients compared to GC patients. There was a significant association of mi R-17 and mi R-106 b expression with age, but not with other clinicopathological features, such as gender, tumor differentiation, stage and lymphatic metastasis. Further analysis showed that, in discriminating GC patients from healthy controls, mi R-17 could yield a receiver-operating characteristic(ROC) area under the curve(AUC) of 0.879 with 80.6% sensitivity and 87.5% specificity and mi R-106 b could yield an AUC of 0.856 with 75.0% sensitivity and 92.5% specificity. The combined AUC of mi R-17 and mi R-106 b was 0.913 with 83.3% sensitivity and 87.5% specificity. Collectively, these data suggest that detection of serum mi R-17 and mi R-106 b levels should be further evaluated as novel non-invasive biomarkers in early GC detection and surveillance of disease progression. | Qinghai Zeng Cuihong Jin Wenhang Chen Fang Xia Qi Wang Fan Fan Juan Du Yihang Guo Changwei Lin Kaiyan Yang Jingjing Li Xiaowei Peng Xiaorong Li Ke Cao | 2014 | Chinese Journal of Cancer Research2014，26，6： | 12 |
| 4 | Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats显示文摘Clinical and animal studies have indicated that propofol has potential for abuse,but the specific neurobiological mechanism underlying propofol reward is not fully understood.The purpose of this study was to investigate the role of extracellular signal-regulated kinase(ERK) signal transduction pathways in the nucleus accumbens(NAc) in propofol self-administration.We tested the expression of p-ERK in the NAc following the maintenance of propofol self-administration in rats.We also assessed the effect of administration of SCH23390,an antagonist of the D1 dopamine receptor,on the expression of p-ERK in the NAc in propofol self-administering rats,and examined the effects of intra-NAc injection of U0126,an MEK inhibitor,on propofol reinforcement in rats.The results showed that the expression of p-ERK in the NAc increased significantly in rats maintained on propofol,and pre-treatment with SCH23390 inhibited the propofol selfadministration and diminished the expression of p-ERK in the NAc.Moreover,intra-NAc injection of U0126(4 μg/side) attenuated the propofol self-administration.The data suggest that ERK signal transduction pathways coupled with D1 dopamine receptors in the NAc may be involved in the maintenance of propofol self-administration and its rewarding effects. | Benfu Wang Xiaowei Yang Anna Sun Lanman Xu Sicong Wang Wenxuan Lin Miaojun Lai Huaqiang Zhu Wenhua Zhou Qingquan Lian | 2016 | Neuroscience Bulletin2016，32，6： | 12 |
| 5 | High precision and efficiency robotic milling of complex parts:Challenges,approaches and trends显示文摘Due to the advantages of large workspace,low cost and the integrated vision/force sensing,robotic milling has become an important way for machining of complex parts.In recent years,many scholars have studied the problems existing in the applications of robotic milling,and lots of results have been made in the dynamics,pose planning,deformation control etc.,which provides theoretical guidance for high precision and high efficiency of robotic milling.From the perspective of complex parts robotic milling,this paper focuses on machining process planning and control techniques including the analysis of the robot-workspace,robot trajectory planning,vibration monitoring and control,deformation monitoring and compensation.As well as the principles of these technologies such as robot stiffness characteristics,dynamic characteristics,chatter mechanisms,and deformation mechanisms.The methods and characteristics related to the theory and technology of robotic milling of complex parts are summarized systematically.The latest research progress and achievements in the relevant fields are reviewed.It is hoped that the challenges,strategies and development related to robotic milling could be clarified through the carding work in this paper,so as to promote the application of related theories and technologies in high efficiency and precision intelligent milling with robot for complex parts. | Zerun ZHU Xiaowei TANG Chen CHEN Fangyu PENG Rong YAN Lin ZHOU Zepeng LI Jiawei WU | 2022 | Chinese Journal of Aeronautics2022，35，2： | 9 |
| 6 | Noninvasive Ultrasound Deep Brain Stimulation for the Treatment of Parkinson’s Disease Model Mouse显示文摘Modulating basal ganglia circuitry is of great signifcance in the improvement of motor function in Parkinson’s disease(PD).Here,for the frst time,we demonstrate that noninvasive ultrasound deep brain stimulation(UDBS)of the subthalamic nucleus(STN)or the globus pallidus(GP)improves motor behavior in a subacute mouse model of PD induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP).Immunohistochemical c-Fos protein expression confrms that there is a relatively high level of c-Fos expression in the STN-UDBS and GP-UDBS group compared with sham group(both p<0.05).Furthermore,STN-UDBS or GPUDBS signifcantly increases the latency to fall in the rotarod test on day 9(p<0.05)and decreases the time spent climbing down a vertical rod in the pole test on day 12(p<0.05).Moreover,our results reveal that STN-UDBS or GP-UDBS protects the dopamine(DA)neurons from MPTP neurotoxicity by downregulating Bax(p<0.001),upregulating Bcl-2(p<0.01),blocking cytochrome c(Cyt C)release from mitochondria(p<0.05),and reducing cleaved-caspase 3 activity(p<0.01)in the ipsilateral substantia nigra(SN).Additionally,the safety of ultrasound stimulation is characterized by hematoxylin and eosin(HE)and Nissl staining;no hemorrhage or tissue damage is detected.Tese data demonstrate that UDBS enables modulation of STN or GP neural activity and leads to neuroprotection in PD mice,potentially serving as a noninvasive strategy for the clinical treatment of PD. | Hui Zhou Lili Niu Long Meng Zhengrong Lin Junjie Zou Xiangxiang Xia Xiaowei Huang Wei Zhou Tianyuan Bian Hairong Zheng | 2019 | Research2019，，1： | 9 |
| 7 | Arbuscular Mycorrhizal Symbiosis Requires a Phosphate Transceptor in the Gigaspora margarita Fungal Symbiont显示文摘陆上的脉管的植物的多数能够形成 mutualistic 协会与要求 biotrophic arbuscular mycorrhizal (AM ) 从门 Glomeromycota 的真菌。这 mutualistic 共生提供糖类给真菌,并且相互地改进植物磷酸盐举起。AM 真菌的 transporters 能通过菌丝的网络从土壤获得磷酸盐。不过, AM 真菌的磷酸盐 transporters 的精确函数,并且他们是否充当传感器或作为滋养的 transporters,在真菌的信号 transduction 仍然保持不清楚。这里,我们从为 AM 共生被要求的 Gigaspora margarita 报导高亲密关系的磷酸盐 transporter GigmPT。GigmPT 的导致主人的基因 silencing 妨碍 G 的发展。margarita 在 AM 期间共生。最重要地, GigmPT 在 G 作为磷酸盐 transceptor 工作。关于表明小径以及蛋白质的磷酸盐的激活的 margarita kinase A 发信号串联。用代用品半胱氨酸可接近性方法,我们识别了残余 A 146( 在 transmembrane 领域[TMD ] IV ) 并且瓦尔 357( 在 TMD VIII ) GigmPT,哪个为磷酸盐在生长期间在酵母发信号和运输是批评的感应。一起,我们的结果从 AM 真菌 G 提供重要卓见进磷酸盐 transceptor 的分子的功能。margarita。 | Xianan Xie Hui Lin Xiaowei Peng Congrui Xu Zhongfeng Sun Kexin Jiang Antian Huang Xiaohui Wu Nianwu Tang Alessandra Salvioli Paola Bonfante Bin Zhao | 2016 | Molecular Plant2016，9，12： | 6 |
| 8 | Diagnosis and surgical treatment of intraveneous leiomyomatosis extending into the heart:two cases report and review of the literature显示文摘Objective:To investigate the clinical characteristics,diagnosis and surgical treatment of intravenous leiomyomatosis(IVL),and outline the differences between Chinese and overseas cases.Methods:Clinical data of two IVL cases,treated in our hospital,were analyzed retrospectively and the related literature was also reviewed.The data of preoperative diagnostic rate,surgical procedures,and postoperative recurrence between patients in China and other countries were compared.Results:The first stage operation was performed successfully in 2 patients.However,they refused subsequent therapies,including a second stage operation to excise the remnants of the tumor,uterus,bilateral oviducts and ovaries,and anti-estrogen therapy.Both suffered from IVL recurrence,one at 6-month and the other at 9-month,and died at 16-month and 12-month respectively after the first stage surgery.Worldwide reports of 110 IVL cases were reviewed,which included 28 cases in China and 82 cases in other countries.In the majority of the Chinese patients,tumors only extended into the right atrium rather than the right ventricle(RA 22 cases vs RV 4 cases).However,among the overseas patients,the rate of extension into the right atrium was similar to that of extension into the right ventricle(RA 41 cases vs RV 38 cases).The rate of hysterectomies was not significantly different between Chinese and overseas patients(67.86% vs 55.9%,P=0.278).The rate of correct preoperative diagnosis in the Chinese patients was significantly lower than that in the overseas patients(32.14% vs 80%,P=0.000002),as well as the rate of complete excision of the tumor(22.7% vs 75.5%,P=0.000001).The proportion of patients who undergoing a single-stage or a two-stage operation was similar in Chinese and overseas patients.The recurrence rate was significantly higher in the Chinese patients than in the overseas patients(36.8% vs 9.1%,P=0.0055),and the patients with tumor recurrence were partial tumor excision patients.Conclusion:The possibility of IVL should be considered if echocardiography in female patients demonstrates a tumor in the right heart and a mass in the inferior vena cava(IVC).Further imaging should be performed to confirm the diagnosis.The correct diagnosis and accurate preoperative delineation of tumor extension are essential for an optimal surgical outcome.The key point in IVL treatment is the complete excision of tumors(single-stage or two-stage surgical procedure). | Xiaowei Wang Lin Zhang Yijiang Chen Shijiang Zhang Jianwei Qin Yanhu Wu Jinhua Luo | 2009 | Journal of Nanjing Medical University2009，23，5： | 5 |
| 9 | Surface modification of LiNi_(1/3)Co_(1/3)Mn_(1/3)O_2 with Cr_2O_3 for lithium ion batteries显示文摘Cr 2 O 3-coated LiNi 1/3 Co 1/3 Mn 1/3 O 2 cathode materials were synthesized by a novel method. The structure and electrochemical properties of prepared cathode materials were measured using X-ray diffraction (XRD), scanning electron microscopy (SEM), charge-discharge tests, cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). The measured results indicate that surface coating with 1.0 wt% Cr 2 O 3 does not affect the LiNi 1/3 Co 1/3 Mn 1/3 O 2 crystal structure (α-NaFeO 2 ) of the cathode material compared to the pristine material, the surfaces of LiNi 1/3 Co 1/3 Mn 1/3 O 2 samples are covered with Cr 2 O 3 well, and the LiNi 1/3 Co 1/3 Mn 1/3 O 2 material coated with Cr 2 O 3 has better electrochemical performance under a high cutoff voltage of 4.5 V. Moreover, at room temperature, the initial discharging capacity of LiNi 1/3 Co 1/3 Mn 1/3 O 2 material coated with 1.0 wt.% Cr 2 O 3 at 0.5C reaches 169 mAh·g 1 and the capacity retention is 83.1% after 30 cycles, while that of the bare LiNi 1/3 Co 1/3 Mn 1/3 O 2 is only 160.8 mAh·g 1 and 72.5%. Finally, the coated samples are found to display the improved electrochemical performance, which is mainly attributed to the suppression of the charge-transfer resistance at the interface between the cathode and the electrolyte. | Li, Xiaowei Lin, Yingbin Liin, Ying Lai, Heng Huang, Zhigao | 2012 | Rare Metals2012，31，2： | 4 |
| 10 | Efficient lung cancer-targeted drug delivery via a nanoparticle/MSC system显示文摘Low targeting efficiency limits the applications of nanoparticles in cancer therapy. The fact that mesenchymal stem cells(MSC) trapped in the lung after systemic infusion is a disadvantage for cell therapy purposes. Here, we utilized MSC as lung cancer-targeted drug delivery vehicles by loading nanoparticles(NP)with anti-cancer drug. MSC showed a higher drug intake capacity than fibroblasts. In addition, MSC showed predominant lung trapping in both rabbit and monkey. IR-780 dye, a fluorescent probe used to represent docetaxel(DTX) in NP, delivered via MSC accumulated in the lung. Both in vitro MSC/A549 cell experiments and in vivo MSC/lung cancer experiments validated the intercellular transportation of NP between MSC and cancer cells. In vivo assays showed that the MSC/NP/DTX drug delivery system exerted primary tumor inhibition efficiency similar to that of a NP/DTX drug system. Collectively, the MSC/NP drug delivery system is promising for lung-targeted drug delivery for the treatment of lung cancer and other lung-related diseases. | Xusheng Wang Haiyan Chen Xiaowei Zeng Wenpeng Guo Yu Jin Shan Wang Ruiyun Tian Yanjiang Han Ling Guo Jimin Han Yaojiong Wu Lin Mei | 2019 | Acta Pharmaceutica Sinica B2019，9，1： | 4 |
| 11 | Mea6 controls VLDL transport through the coordinated regulation of COPil assembly显示文摘 | Yaqing Wang Liang Liu Hongsheng Zhang Junwan Fan FengZhang Mei Yu Lei Shi Lin Yang Sin Man Lam Huimin Wang Xiaowei Chen Yingchun Wang Fei Gao Guanghou Shui Zhiheng Xu | 2016 | Cell Research2016，26，7： | 4 |
| 12 | Divergent patterns of foliar δ^(13)C and δ^(15)N in Quercus aquifolioides with an altitudinal transect on the Tibetan Plateau: an integrated study based on multiple key leaf functional traits显示文摘Aims With a close association with plant water availability,foliar δ^(13)C had been investigated extensively in alpine regions;however,foliar δ^(15)N has rarely been concurrently used as an indicator of plant nitrogen availability.Due to the positive correlations between leaf nitrogen con-tent and foliar δ^(13)C andδ15N found in previous studies,we expected that they should show consistent patterns along an altitudinal gradient.Methods To test our hypothesis,we measured foliar δ^(13)C andδ15N in conjunc-tion with multiple key leaf functional traits of Quercus aquifolioides,a dominant species of alpine forest on the eastern slopes of the sygera mountains,southeastern Tibetan Plateau from 2500 to 3800 m.Important findings(i)Contrary to our hypothesis,foliar δ^(13)C exhibited a significant pos-itive linear relationship with altitude;in contrast,foliarδ15N initially increased and subsequently decreased with altitude,the change in trend occurring around 3300 m.(ii)our analyses indicated that leaf internal resistance and stomatal conductance,rather than photosynthetic capacity indicated by leaf N concentration,appar-ently explained the altitudinal variation in foliar δ^(13)C,while differ-ences in foliar δ^(15)N were likely the result of soil N availability.(iii)Principal component analysis revealed a clear association between δ^(13)C and a tradeoff between water loss and carbon gain,indicated by traits related to gas exchange such as leaf thickness,density,sto-matal properties.In contrast,the second axis was associated withδ15N and nitrogen acquisition strategy in Q.aquifolioides across its altitudinal distribution,represented by traits related to nitrogen concentration and stomata per gram of leaf nitrogen. | Litong Chen Dan F.B.Flynn Xiaowei Zhang Xianliang Gao Ling Lin Jian Luo Changming Zhao | 2015 | Journal of Plant Ecology2015，8，3： | 4 |
| 13 | Enhancing rice grain production by manipulating the naturally evolved cis-regulatory element-containing inverted repeat sequence of OsREM20显示文摘Grain number per panicle(GNP)is an important agronomic trait that contributes to rice grain yield.Despite its importance in rice breeding,the molecular mechanism underlying GNP regulation remains largely unknown.In this study,we identified a previously unrecognized regulatory gene that controls GNP in rice,Oryza sativa REPRODUCTIVE MERISTEM 20(OsREM20),which encodes a B3 domain transcription factor.Through genetic analysis and transgenic validation we found that genetic variation in the CArG box-containing inverted repeat(IR)sequence of the OsREM20 promoter alters its expression level and contributes to GNP variation among rice varieties.Furthermore,we revealed that the IR sequence regulates OsREM20 expression by affecting the direct binding of OsMADS34 to the CArG box within the IR sequence.Interestingly,the divergent pOsREM20IR and pOsREM20ΔIR alleles were found to originate from different Oryza rufipogon accessions,and were independently inherited into the japonica and indica subspecies,respectively,during domestication.Importantly,we demonstrated that IR sequence variations in the OsREM20 promoter can be utilized for germplasm improvement through either genome editing or traditional breeding.Taken together,our study characterizes novel genetic variations responsible for GNP diversity in rice,reveals the underlying molecular mechanism in the regulation of agronomically important gene expression,and provides a promising strategy for improving rice production by manipulating the cis-regulatory element-containing IR sequence. | Xiaowei Wu Yan Liang Hengbin Gao Jiyao Wang Yan Zhao Lekai Hua Yundong Yuan Ahong Wang Xiaohui Zhang Jiafan Liu Jie Zhou Xiangbing Meng Dahan Zhang Shaoyang Lin Xuehui Huang Bin Han Jiayang Li Yonghong Wang | 2021 | Molecular Plant2021，14，6： | 3 |
| 14 | Electrochemical properties of carbon-coated LiFePO_4 and LiFe_(0.98)Mn_(0.02)PO_4 cathode materials synthesized by solid-state reaction显示文摘Olivine structured LiFePO 4 /C (lithium iron phosphate) and Mn 2+ -doped LiFe 0.98 Mn 0.02 PO 4 /C powders were synthesized by the solid-state reaction. The effects of manganese partial substitution and different carbon content coating on the surface of LiFePO 4 were considered. The structures and electrochemical properties of the samples were measured by X-ray diffraction (XRD), cyclic voltammetry (CV), charge/discharge tests at different current densities, and electrochemical impedance spectroscopy (EIS). The electrochemical properties of LiFePO 4 cathodes with x wt.% carbon coating (x= 3, 7, 11, 15) at =0.2C, 2C (1C= 170 mAh·g 1 ) between 2.5 and 4.3 V were investigated. The measured results mean that the LiFePO 4 with 7 wt.% carbon coating shows the best rate performance. The discharge capacity of LiFe 0.98 Mn 0.02 PO 4 /C composite is found to be 165 mAh·g 1 at a discharge rate, = 0.2C, and 105 mAh·g 1 at =2C, respectively. After 10 cycles, the discharge capacity has rarely fallen, while that of the pristine LiFePO 4 /C cathode is 150 mAh·g 1 and 98 mAh·g 1 at =0.2 and 2C, respectively. Compared to the discharge capacities of both electrodes above, the evident improvement of the electrochemical performance is observed, which is ascribed to the enhancement of the electronic conductivity and diffusion kinetics by carbon coating and Mn 2+-substitution. | Lin, Ying Zeng, Baozhi Lin, Yingbin Li, Xiaowei Zhao, Guiying Zhou, Ting Lai, Heng Huang, Zhigao | 2012 | Rare Metals2012，31，2： | 3 |
| 15 | Development and application of a loop-mediated isothermal amplification method on rapid detection Escherichia coli O157 strains from food samples显示文摘 | Xihong Zhao Yanmei Li Li Wang Lijun You Zhenbo Xu Lin Li Xiaowei He Yao Liu Jihua Wang Liansheng Yang | 2010 | Molecular Biology Reports2010，，5： | 3 |
| 16 | Mesoporous TiO_2/Carbon Beads: One-Pot Preparation and Their Application in Visible-Light-Induced Photodegradation显示文摘Mesoporous Ti O2/Carbon beads have been prepared via a facile impregnation-carbonization approach, in which a porous anion-exchange resin and K2 Ti O(C2O4)2were used as hard carbon and titanium source, respectively.Characterization results reveal that the self-assembled composites have disordered mesostructure, uniform mesopores,large pore volumes, and high surface areas. The mesopore walls are composed of amorphous carbon, well-dispersed and confined anatase or rutile nanoparticles. Some anatase phase of Ti O2 was transformed to rutile phase via an increase of carbonization temperature or repeated impregnation of the resin with Ti O(C2O4)22-species. X-ray photoelectron spectroscopy, carbon, hydrogen, and nitrogen element analysis, and thermal gravity analysis results indicate the doping of carbon into the Ti O2 lattice and strong interaction between carbon and Ti O2 nanoparticles. A synergy effect by carbon and Ti O2 in the composites has been discussed herein on the degradation of methyl orange under visible light. The dye removal process involves adsorption of the dye from water by the mesopores in the composites, followed by photodegradation on the separated dye-loaded catalysts. Mesopores allow full access of the dye molecules to the surface of Ti O2 nanoparticles.Importantly, the bead format of such composite enables their straightforward separation from the reaction mixture in their application as a liquid-phase heterogeneous photodegradation catalyst. | Xiaowei Li Yanqiu Jiang Wenjing Cheng Yudong Li Xianzhu Xu Kaifeng Lin | 2015 | Nano-Micro Letters2015，7，3： | 2 |
| 17 | Conceptual design of energy-saving stripping process for industrial sour water显示文摘Sour water contains ammonia,carbon dioxide,and hydrogen sulfides,producing from oil refining,coking,and coal gasification.To reduce the energy consumption in sour water stripping,a novel process is proposed which integrates with the bottom flashing mechanical vapor recompression heat pump(MVRHP)for treating such wastewater.Here,Aspen PlusTM as a powerful set of chemical process simulation software is utilized to investigate the economy and feasibility of the novel process.Comparison of the results of two process simulations,it can be seen that it is possible to reduce the total annual cost by nearly 45%to adopt the novel process,despite the capital investment increase 45%more than the conventional process.Thus,the provided conceptual design will play a guiding role in the industrialization of the process. | Hengjun Gai Shuo Chen Kaiqiang Lin Xiaowei Zhang Chun Wang Meng Xiao Tingting Huang Hongbing Song | 2020 | Chinese Journal of Chemical Engineering2020，28，5： | 2 |
| 18 | Electrochemical lithium ions pump for lithium recovery from brine by using a surface stability Al_(2)O_(3)–ZrO_(2 )coated LiMn_(2)O_(4) electrode显示文摘The rapid commercialization of lithium–ion batteries has caused significant expansion of the lithium demand.Electrochemical lithium ions pump is a promising technology because of its good selectivity and friendly environment.Herein,an Al_(2)O_(3)–ZrO_(2) film coating of the LiMn_(2)O_(4)(AlZr–LMO) electrode is prepared and operated for recovery of Li^(+)from brine.The Li^(+) maximum extraction capacity of AlZr–LMO reached 49.92 mg/g in one cycle.Compared with the solely LMO electrode,the AlZr–LMO demonstrated evident electrochemical stability and cycle life towards the Li^(+)recovery system.After 30 successive cycles,the extraction capacity for Li^(+)increased from 29.21%to 57.67%.The high cycle capacity of the material could be attributed to its low polarization,high active sites,and good chemical stability of the electrode surface owing to the synergy function of Al_(2)O_(3)–ZrO_(2)in the charging-discharging process.A dynamic model parameter identification method was performed to evaluate the active site of AlZr–LMO.This work may provide a way to design the AlZr–LMO electrode and develop a good method for the recovery of lithium from brine. | Guiling Luo Lin Zhu Xiaowei Li Guolang Zhou Jing Sun Linlin Chen Yanhong Chao Lei Jiang Wenshuai Zhu | 2022 | Journal of Energy Chemistry2022，31，6： | 2 |
| 19 | Integrated Wide Area Protection and Control for Power Grid Security显示文摘The traditional“three defense lines”for power systems are based on local information and static protection&control strategy,which are not suitable to modern large-scale power systems.In order to improve the security of UHV hybrid power grids,the Integrated Wide Area Protection&Control(IWAPC)is proposed in this paper by applying the new technologies of synchronized high-speed communication,which integrates“three defense lines”and promotes existing wide area protection only for security control.The IWAPC is the hierarchical protection and control system which provides the protection and control for wide area power networks to improve their reliability and security.It is divided into three levels,the local bay level,the substation integrated protection level and the wide area protection level.The wide area real-time protection and control information platform is the most important part of the IWAPC,which is based on a synchronized wide area communication network.The key technologies and new development trends include network topology analysis,wide area backup protection,wide area intelligent reclosing,wide area load shedding,wide area auto-switching,overload cutoff and transfer,transmission section protection,intelligent system splitting and dynamic stability control.It cannot only integrate three lines of defense for power system protection and control,but also improve security of the power grid. | Qingping Wang Zhiqian Bo Yingke Zhao Xiaowei Ma Ming Zhang Hao Zheng Lin Wang | 2019 | CSEE Journal of Power and Energy Systems2019，5，2： | 2 |
| 20 | 2021 Chinese consensus on the diagnosis and management of primary immune thrombocytopenia in pregnancy显示文摘Immune thrombocytopenia(ITP)is an acquired disease characterized by isolated thrombocytopenia,which is one of the most common causes of thrombocytopenia during pregnancy.Women with ITP who have severe thrombocytopenia are at an increased risk for life-threatening obstetric complications.Therefore,we established this consensus statement on the diagnosis and management of ITP during pregnancy(detailed information is available in the Supplementary File,http://gffzz16e312a87a7141a5h0c6vcqqvx0ff6k0u.ffgz.tsg.suse.edu.cn/A978). | Zhang Xiaohui Chen Fangping Chen Xiequn Cheng Yunfeng Fang Meiyun Feng Jianming Fu Haixia Gao Hong Han Yue He Aili Hou Ming Hu Yu Huang Ruibin Huang Wenrong Jing Zhicheng Kong Peiyan Liang Aibin Liang Meiying Liu Daihong Liu Junling Liu Lin Liu Xiaowei Ma Liangming Mei Heng Ni Heyu Niu Ting Peng Jun Qiao Jianlin Ren Jinhai Song Yongping Tang Liang V Tong Tong Wang Shaoyuan Wang Xin Wang Zhao Wei Hui Wu Depei Wu Guangsheng Xu Caigang Xu Xue Xu Yajing Yang Linhua Yang Renchi Yang Tonghua Yin Chenghong Yu Li Zhang Guangsen Zhang Lei Zhang Liansheng Zhang Xi Zhao Weili Zhao Yongqiang Zhou Daobin Zhou Hu Zhou Zeping Zhu Tienan Wang Jianliu Huang Xiaojun | 2022 | Chinese Medical Journal2022，，8： | 2 |
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