4篇
您的检索式：作者名="Liangping Hu"
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| 1 | Resistivity response of coal under hydraulic fracturing with different injection rates:A laboratory study显示文摘Resistivity will have different response characteristics to the hydraulic fracture propagation process. In this work, a resistivity testing system for hydraulic fracturing specimens was established. Resistivity and acoustic emission(AE) information were jointly analysed to determine the dynamic response characteristics of resistivity during hydraulic fracture propagation. The results show that the water and fracture exert a competitive influence on the connection structure of the circuit, and there are two significant peak resistivity points in the curve, presenting a double peak therein. The peak resistivity data of the specimen with a larger fracture area are much different from the initial value. With the increase of the rate of injection, the range of variation of the highest value that can be reached with the specimen resistivity decreases. High resistivity rates or high resistivity fluctuations exhibit rapid a release of fracture energy. The fracture failure mode dominated by shear fractures makes the formation produce a “series+parallel” electrical connection structure;a calculation model of formation resistivity based on shear and tensile failure was proposed to characterize the proportion of different types of hydraulic fractures and elucidate the control effect of matrix resistivity on the electrical performance of the overall circuit structure. | Mingyang Song Quangui Li Qianting Hu Yanqing Wu Guanhua Ni Yangcheng Xu Yuebing Zhang Liangping Hu Jialin Shi Jichuan Liu Yize Deng | 2022 | International Journal of Mining Science and Technology2022，32，4： | 1 |
| 2 | Effects of Mechanical Activation on the HCl Leaching Behavior of Titanaugite, Ilmenite, and Their Mixtures显示文摘 | Li Zhang Huiping Hu Liangping Wei Qiyuan Chen Jun Tan | 2010 | Metallurgical and Materials Transactions B2010，，6： | 1 |
| 3 | A multifunctional nanotheranostic agent potentiates erlotinib to EGFR wild-type non-small cell lung cancer显示文摘Epidermal growth factor receptor(EGFR)tyrosine kinase inhibitors(TKI),such as Erlotinib,have demonstrated remarkable efficacy in the treatment of non-small cell lung cancer(NSCLC)patients with mutated EGFR.However,the efficacy of EGFR-TKIs in wild-type(wt)EGFR tumours has been shown to be marginal.Methods that can sensitize Erlotinib to EGFR wild-type NSCLC remain rare.Herein,we developed a multifunctional superparamagnetic nanotheranostic agent as a novel strategy to potentiate Erlotinib to EGFR-wt NSCLCs.Our results demonstrate that the nanoparticles can co-escort Erlotinib and a vascular epithermal growth factor(VEGF)inhibitor,Bevacizumab(Bev),to EGFR-wt tumours.The nanotheranostic agent exhibits remarkable effects as an inhibitor of EGFR-wt tumour growth.Moreover,Bev normalizes the tumour embedded vessels,further promoting the therapeutic efficacy of Erlotinib.In addition,the tumour engagement of the nanoparticles and the vascular normalization could be tracked by magnetic resonance imaging(MRI).Collectively,our study,for the first time,demonstrated that elaborated nanoparticles could be employed as a robust tool to potentiate Erlotinib to EGFR-wt NSCLC,paving the way for imaging-guided nanotheranostics for refractory NSCLCs expressing EGFR wild-type genes. | Duo Wang Jun Zhou Weimin Fang Cuiqing Huang Zerong Chen Meng Fan Ming-Rong Zhang Zeyu Xiao Kuan Hu Liangping Luo | 2022 | Bioactive Materials2022，7，7： | 0 |
| 4 | Probing surface structure on two-dimensional metal-organic layers to understand suppressed interlayer packing显示文摘Two-dimensional metal-organic layers(MOLs)from alternatively connected benzene-tribenzoate ligands and Zr6(μ3-O)_(4)(μ3-OH)_(4) or Hf6(μ3-O)_(4)(μ3-OH)_(4) secondary building units can be prepared in gram scale via solvothermal synthesis.However,the reason why the monolayers did not pack to form thick crystals is unknown.Here we investigated the surface structure of the MOLs by a combination of sum-frequency generation spectroscopy,nanoscale infrared microscopy,atomic force microscopy,aberration-corrected transmission electron microscopy,and compositional analysis.We found a partial coverage of the monolayer surface by dangling tricarboxylate ligands,which prevent packing of the monolayers.This finding illustrates low-density surface modification as a strategy to prepare new two-dimensional materials with a high percentage of exposed surface. | Peican Chen Yi Liu Xuefu Hu Xiaolin Liu En-Ming You Xudong Qian Jiawei Chen Liangping Xiao Lingyun Cao Xinxing Peng Zhongming Zeng Yibing Jiang Song-Yuan Ding Honggang Liao Zhaohui Wang Da Zhou Cheng Wang | 2020 | Nano Research2020，13，11： | 0 |
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