|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Experimental Investigation and Thermodynamic Reassessment of the Cu-Fe-Si System显示文摘 | Jingrui Zhao Lijun Zhang Yong Du Honghui Xu Jianlie Liang Baiyun Huang | 2009 | Metallurgical and Materials Transactions A2009，，8： | 1 |
| 2 | Sinoatrial node pacemaker cells share dominant biological properties with glutamatergic neurons显示文摘Activation of the heart normally begins in the sinoatrial node(SAN).Electrical impulses spontaneously released by SAN pacemaker cells(SANPCs)trigger the contraction of the heart.However,the cellular nature of SANPCs remains controversial.Here,we report that SANPCs exhibit glutamatergic neuron-like properties.By comparing the single-cell transcriptome of SANPCs with that of cells from primary visual cortex in mouse,we found that SANPCs co-clustered with cortical neurons.Tissue and cellular imaging confirmed that SANPCs contained key elements of glutamatergic neurotransmitter system,expressing genes encoding glutamate synthesis pathway(G/s),ionotropic and metabotropic glutamate receptors(Grina,Gria3,Grm1 and Grm5)t and glutamate transporters(Slc17a7).SANPCs highly expressed cell markers of glutamatergic neurons(Snap25 and S/-c17a7)t whereas Gad1,a marker of GABAergic neurons,was negative.Functional studies revealed that inhibition of glutamate receptors or transporters reduced spontaneous pacing frequency of isolated SAN tissues and spontaneous Ca2+transients frequency in single SANPC.Collectively,our work suggests that SANPCs share dominant biological properties with glutamatergic neurons,and the glutamatergic neurotransmitter system may act as an intrinsic regulation module of heart rhythm,which provides a potential intervention target for pacemaker cell-associated arrhythmias. | Dandan Liang Zhigang Xue Jinfeng Xue Duanyang Xie Ke Xiong Huixing Zhou Fulei Zhang Xuling Su Guanghua Wang Qicheng Zou Yi Liu Jian Yang Honghui Ma Luying Peng Chunyu Zeng Gang Li Li Wang Yi-Han Chen | 2021 | Protein & Cell2021，12，7： | 1 |
| 3 | Protective behavior of an SO_2/CO_2 gas mixture for molten AZ91D alloy显示文摘The protective behavior for a molten AZ91D alloy in an open melting furnace was investigated under a protective gas mixture containing 3% SO2 and 97% CO2, and the protection mechanism was discussed. Experimental results show that the gas mixture provides effective protection for AZ91D melt in the temperature range from 680 oC to 730 oC. The microstructure, chemical composition and phase composition of the surface film formed on the molten AZ91D alloy were analyzed using scanning electron microscopy (SEM) with energy dispersive spectrometer (EDS) and X-ray diffraction (XRD). The SEM results demonstrate that the surface films with an average thickness between 0.5 μm and 2 μm are dense and coherent in the protected temperature range. The EDS results reveal that the surface film mainly contains elements S, C, O, Al and Mg. The XRD results show that the surface film consists of MgO, MgS and a small amount of C phase. | Liang Weizhong Gao Qiu Chen Fu Liu Honghui Zhao Zhenhua | 2012 | China Foundry2012，9，3： | 1 |
| 4 | Burch colposuspension for stress urinary incontinence: a 14-year prospective follow-up显示文摘We aimed to evaluate the long-term effectiveness and safety of Burch colposuspension(BC) for stress urinary incontinence(SUI). In this prospective cohort study, 84 patients with SUI undergoing BC were enrolled from February 2004 to January 2010.Data on long-term subjective success and postoperative complications were collected at clinic visits and by telephone follow-up.During a mean follow-up period of 14.2 years, 68%(57/84) patients completed the follow-up. A total of 68.4% of patients(39/57) reported absence of SUI symptoms, 73.6%(42/57) were subjectively satisfied according to the Patient Global Impression of Improvement, and 68.4%(39/57) reported subjective success regarding urinary symptoms via the Urinary Distress Inventory Short Form. However, 28.1%(16/57) suffered at least one long-term postoperative complication and incident. Specifically, 1 in25(4.0%) sexually active patients reported dyspareunia, 3 patients(5.3%) had de novo overactive bladder, and 6 patients(10.5%)reported voiding dysfunction. Four patients(7.0%) reported new onset prolapse symptoms, and 3 patients(5.3%) underwent secondary urinary incontinence surgery. Our study indicated that Burch colposuspension is an effective procedure for SUI, and the cure effect was largely maintained for the 14-year follow-up period, with relatively low complication rates. BC should be considered a surgical option for SUI. | Yang Ye Yuan Wang Weijie Tian Zhibo Zhang Shuo Liang Xiaochen Song Jianbin Guo Qianqian Gao Honghui Shi Zhijing Sun Juan Chen Jinghe Lang Lan Zhu | 2022 | Science China(Life Sciences)2022，65，8： | 1 |
| 5 | Quantum Dot Nanobeads-Labelled Lateral Flow Immunoassay Strip for Rapid and Sensitive Detection of Salmonella Typhimurium Based on Strand Displacement Loop-Mediated Isothermal Amplification显示文摘Rapid,sensitive,point-of-care detection of pathogenic bacteria is important for food safety.In this study,we developed a novel quantum dot nanobeads-labelled lateral flow immunoassay strip(QBs-labelled LFIAS)combined with strand displacement loop-mediated isothermal amplification(SD-LAMP)for quantitative Salmonella Typhimurium(ST)detection.Quantum dot nanobeads(QBs)served as fluorescence reporters,providing good detection efficiency.The customizable strand displacement(SD)probe was used in LAMP to improve the specificity of the method and prevent by-product capture.Detection was based on a sandwich immunoassay.A fluorescence strip reader measured the fluorescence intensity(FI)of the test(T)line and control(C)line.The linear detection range of the strip was 10^(2)–10^(8) colony forming units(CFU)·mL^(-1).The visual limit of detection was 10^(3) CFU·mL^(-1),indicating that the system was ten-fold more sensitive than AuNPs-labelled test strips.ST specificity was analyzed in accordance with agarose gel outputs of polymerase chain reaction(PCR)and SD-LAMP.We detected ST in foods with an acceptable recovery of 85%–110%.The method is rapid,simple,almost equipment-free,and suitable for bacterial detection in foods and for clinical diagnosis. | Yuting Shang Shuzhen Cai Qinghua Ye Qingping Wu Yanna Shao Xiaoying Qu Xinran Xiang Baoqing Zhou Yu Ding Moutong Chen Liang Xue Honghui Zhu Jumei Zhang | 2022 | Engineering2022，，12： | 0 |
| 6 | Phylogenetic relationships of host insects of Cordyceps sinensis inferred from mitochondrial Cytochrome b sequences显示文摘这研究使用了 mitochondrial 细胞色素 b (Cytb ) 的顺序在 Cordyceps sinensis 的主人 Hepialidae 昆虫之中估计种系发生的关系。宿主昆虫的染色体 DNA 从 18 张 cordyceps 人口的死了的幼虫的头部分被提取, Hepialus 的 2 种类,和 Cytb 宿主昆虫碎裂与 PCR 被放大技术。核苷酸顺序排列和他们 Cordyceps sinensis 的 24 只种类主人 Hepialidae 昆虫的相应序列从 GenBank 被获得并且被用来基于加入邻居的方法构造种系发生的树。结果证明类 Bipectilus 比类 Hepialus Hepialiscus 早分叉。Cordyceps sinensis 的 Hepialus 宿主昆虫与不同词法特征和地理分布有大群的种类。种间的基因区别在 Hepialus 是明显的。因此,类 Hepialus 可能被看作 polyphyletic 起源。Cytb 序列在特定、通用的水平上在 Cordyceps ninensis 的主人昆虫之中有丰富的变化。在在 Hepialus 的种类之中的 Cytb 序列的分叉率从 0.23% ~ 9.24%,除了 Hepialus pratensis 和 Hepialus jinshaensis 有一样的顺序之外。Cytb 顺序能被用于 Cordyceps sinensis 的主人昆虫的种类鉴定,但是推进证实在在先,主人昆虫种类被需要。为了由放大 DNA 获得主人昆虫的 Cytb 顺序,外面从在 cordyceps 拐弯幼虫的死者的头部分提取了是有效、精确的 apprach ,它将为发展史和 cordyceps 人口的主人昆虫的基因结构上的研究是有用的,特别为分析在 C.sinensisand 之间的关系它的主人昆虫。 | Cheng Zhou Geng Yang Liang Honghui Yang Xiaoling Li Shan | 2007 | Progress in Natural Science:Materials International2007，17，7： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员