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| 1 | Upper mantle anisotropy in the Ordos Block and its margins显示文摘Based on the polarization analysis of teleseismic data,SKS (SKKS) fast-wave directions and delay times between fast and slow shear waves were determined for each of the 111 seismic stations from both permanent and temporary broadband seismograph networks deployed in the Ordos Block and its margins.Both the Silver and Chan and stacking analysis methods were used.In this way,an image of upper mantle anisotropy in the Ordos Block and its margins was acquired.In the western and northern margins of the Ordos Block,the fast-wave directions are consistently NW-SE.The fast-wave directions are mainly NWW-SEE and EW in the southern margin of the Ordos Block.In the eastern margin of the Ordos Block,the fast-wave directions are generally EW,although some run NEE-SWW or NWW-SEE.In the Ordos Block,the fast-wave directions trend near N-S in the north,but switch to near EW in the south.The delay time between fast and slow waves falls into the interval 0.48-1.50 s,and the average delay time at the stations in the Ordos Block is less than that in its margins.We suggest that the anisotropy of the stable Ordos Block is mainly caused by 'fossil' anisotropy frozen in the ancient North China Craton.The NE-trending push of the northeastern margin of the Tibetan Plateau has caused NW-SE-trending lithospheric extension in the western and northern margins of the Ordos Block,and made the upper mantle flow southeastwards.This in turn has resulted in the alignment of the upper mantle peridotite lattice with the direction of material deformation.In the southern margin of the Ordos Block,the collision between the North China and Yangtze blocks resulted in the fast-wave direction running parallel to the collision boundary and the Qinling Orogen.Combining this with the APM and velocity structure of the Qinling Orogen,we propose that eastward-directed asthenospheric-mantle channel flow may have occurred beneath the Qinling Orogen.In the eastern margin of the Ordos Block,the complex anisotropic characteristics of the Fenhe Graben and Taihang Orogen may be caused by the interaction of western Pacific Plate subduction,regional extensional tectonics,and the orogeny.For station YCI,the apparent splitting parameters (the fast-wave directions range from 45° to 106° and the delay times range from 0.6 to 1.5 s) exhibit systematic variations as a function of incoming polarization with a periodicity of π/2.This variation can be best explained by a two-layer anisotropic model (φlower=132°,δtlower=0.8 s,φupper=83°,δtupper=0.5 s).The upper layer anisotropy beneath station YCI can again be attributed to 'fossil' anisotropy frozen in the ancient North China Craton.The lower layer anisotropy is affected by the tectonic activity of the western Ordos Block.The NW-SE trending extension caused by the NE trending push of the northeastern margin of the Tibetan Plateau affected the deformation of the lower anisotropic layer beneath station YCI.By comparing the fast-wave directions with GPS velocity directions,we see that the crust and upper mantle possibly have vertically coherent deformation in the margins of the Ordos Block,whereas the internal deformation characteristics of the Ordos Block are complex and require further study. | CHANG LiJun WANG ChunYong DING ZhiFeng | 2011 | Science China Earth Sciences2011，54，6： | 25 |
| 2 | Pollutants in stormwater runoff in Shanghai (China): Implications for management of urban runoff pollution显示文摘Runoff samples were collected from four functional areas (traffic, residential, commercial and industrial) and four roof types (old concrete, new concrete, old clay and new clay) in central Shanghai, China, during rain events. The event mean concentrations (EMCs) of three forms of nitrogen eNH4tAN;NO3 AN;NO2 ANT and the temporal variations of total phosphorus (TP) were then measured to evaluate the effects of runoff from different areas on water quality management. The results revealed that the TP levels varied significantly in the samples collected from different functional areas and roof types during rain events. In addition, although the NO3 AN and NO2 AN concentrations in runoff remained well below the fifth class values of the national surface water quality standards, the NH4tAN levels were 1.36, 1.17, 1.10 and 0.85 times higher than the standard value in samples collected from commercial, traffic, industrial, and residential areas, respectively. Similarly, the concentrations of NH4tAN in samples collected from old concrete, new concrete, old clay and new clay roofs exceeded the fifth class standard by 6.66, 5.72, 4.32 and 3.32 times, respectively. And the NO3 AN levels were 1.86 and 1.53 times higher than the standard values in runoff samples collected from new and old concrete roofs, respectively. | Siaka Ballo Min Liu Lijun Hou Jing Chang | 2009 | Progress in Natural Science:Materials International2009，19，7： | 22 |
| 3 | Seismic anisotropy of upper mantle in eastern China显示文摘Based on the polarization analysis of teleseismic SKS waveform data recorded at 65 seismic stations which respectively involved in the permanent and temporary broadband seismograph networks deployed in eastern China, the SKS fast-wave direction and the delay time between the fast and slow shear waves at each station were determined by use of SC method and the stacking analysis method, and then the image of upper mantle anisotropy in eastern China was acquired. In the study region, from south to north, the fast-wave polarization directions are basically EW in South China, gradually clockwise rotate to NWW-SEE in North China, then to NW-SE in Northeast China. The delay time falls into the interval [0.41 s, 1.52 s]. Anisotropic characteristics in eastern China indicate that the upper mantle anisotropy is possibly caused by both the collision between the Indian and Eurasian Plates and the subduction from the Pacific and Philippine Sea Plates to the Eurasian Plate. The collision between two plates made the crust of western China thickening and uplifting and the material eastwards extruding, and then caused the upper mantle flow eastwards and southeastwards. The subduction of Pacific Plate and Philippine Sea Plate has resulted in the lithosphere and the asthenosphere deformation in eastern China, and made the alignment of upper mantle peridotite lattice parallel to the deformation direction. The fast-wave polarization direction is consistent with the direction of lithosphere extension and the GPS velocity direction, implying that the crust-upper mantle deformation is possibly a vertically coherent deformation. | CHANG LiJun WANG ChunYong Ding ZhiFeng | 2009 | Science China Earth Sciences2009，52，6： | 21 |
| 4 | Genome-Wide Association Studies of Image Traits Reveal Genetic Architecture of Drought Resistance in Rice显示文摘理解植物怎么对干旱作出回应能有益于繁殖的干旱抵抗(医生) 。用一台非破坏性的 phenotyping 设备,为 507 米饭就职的 51 个基于图象的特点(i 特点) 被提取。这些 i 特点能被用来监视干旱回答 ? 并且高评估医生可遗传性和这些特点的大变化在自然人口在干旱应力下面被观察。染色体宽的协会研究(GWAS )?i 特点和传统的医生特点识别了 470 协会 loci,某包含知道医生相关的基因。这 470 loci, 443 loci (94%) 用 i 特点被识别, 437 loci (93%) 与以前报导的医生相关的量的特点 loci,和 313 loci (66.6%)co 局部性被 GWAS reproducibly 在不同的年里识别。协会网络,基于 GWAS 建立了结果,揭示中心 i 特点和中心 loci。这表明把的可行性和必要性复杂医生特点进可继承、简单的 i 特点。作为原则的证明,我们说明了这条综合途径的力量以前识别 unreported 医生相关的基因。OsPP15 与中心 i 特点被联系,并且它在医生的角色被基因转变实验证实。而且, i 特点能被用于医生连接分析,并且 69 个 i 特点地点协会被 recombinant 的 GWAS 和连接分析识别生来的线人口。最后,我们证实了 i 特点的关联在这个领域里搀。我们的学习为医生为原因的基因的基因解剖和发现提供一条有希望的新奇途径。 | Zilong Guo Wanneng Yang Yu Chang Xiaosong Ma Haifu Tu Fang Xiong Ni Jiang Hui Feng Chenglong Huang Peng Yang Hu Zhao Guoxing Chen Hongyan Liu Lijun Luo Honghong Hu Qian Liu Lizhong Xiong | 2018 | Molecular Plant2018，11，6： | 21 |
| 5 | Upper mantle anisotropy and crust-mantle deformation pattern beneath the Chinese mainland显示文摘Over the past 10 years,the number of broadband seismic stations in China has increased significantly.The broadband seismic records contain information about shear-wave splitting which plays an important role in revealing the upper mantle anisotropy in the Chinese mainland.Based on teleseismic SKS and SKKS phases recorded in the seismic stations,we used the analytical method of minimum transverse energy to determine the fast wave polarization direction and delay time of shear-wave splitting.We also collected results of shear-wave splitting in China and the surrounding regions from previously published papers.From the combined dataset we formed a shear-wave splitting dataset containing 1020 parameter pairs.These splitting parameters reveal the complexity of the upper mantle anisotropy image.Our statistical analysis indicates stronger upper mantle anisotropy in the Chinese mainland,with an average shear-wave time delay of 0.95 s;the anisotropy in the western region is slightly larger(1.01 s)than in the eastern region(0.92 s).On a larger scale,the SKS splitting and surface deformation data in the Tibetan Plateau and the Tianshan region jointly support the lithospheric deformation mode,i.e.the crust-lithospheric mantle coherent deformation.In eastern China,the average fast-wave direction is approximately parallel to the direction of the absolute plate motion;thus,the upper mantle anisotropy can be attributed to the asthenospheric flow.The area from the Ordos block to the Sichuan Basin in central China is the transition zone of deformation modes between the east and the west regions,where the anisotropy images are more complicated,exhibiting'fossil'anisotropy and/or two-layer anisotropy.The collision between the Indian Plate and the Eurasian Plate is the main factor of upper mantle anisotropy in the western region of the Chinese mainland,while the upper mantle anisotropy in the eastern region is related to the subduction of the Pacific Plate and the Philippine Sea Plate beneath the Eurasian Plate. | WANG ChunYong CHANG LiJun DING ZhiFeng LIU QiongLin LIAO WuLin Lucy M FLESCH | 2014 | Science China Earth Sciences2014，57，1： | 18 |
| 6 | Seismic anisotropy of upper mantle in Sichuan and adjacent regions显示文摘Based on the polarization analysis of teleseismic SKS waveform data recorded at 94 broadband seis-mic stations in Sichuan and adjacent regions, the SKS fast-wave direction and the delay time between the fast and slow shear waves were determined at each station using the grid searching method of minimum transverse energy and the stacking analysis method, and the image of upper mantle anisot-ropy was acquired. The fast-wave polarization directions are mainly NW-SE in the study area, NWW-SEE to its northeast and NS to its west. The delay time falls into the interval [0.47 s, 1.68 s]. The spatial variation of the fast-wave directions is similar to the variation of GPS velocity directions. The anisotropic image indicates that the regional tectonic stress field has resulted in deformation and flow of upper mantle material, and made the alignment of upper mantle peridotite lattice parallel to the di-rection of material deformation. The crust-upper mantle deformation in Sichuan and adjacent regions accords with the mode of vertically coherent deformation. In the eastern Tibetan Plateau, the crustal material was extruded to east or southeast due to SE traction force of the upper mantle material. The extrusion might be obstructed by a rigid block under the Sichuan Basin and the crust has been de-formed. After a long-term accumulation of tectonic strain energy, the accumulative energy suddenly released in Yingxiu town of the Longmenshan region, and Wenchuan MS8.0 earthquake occurred. | CHANG LiJun WANG ChunYong DING ZhiFeng | 2008 | Science China Earth Sciences2008，51，12： | 16 |
| 7 | Upper mantle anisotropy of the eastern Himalayan syntaxis and surrounding regions from shear wave splitting analysis显示文摘Polarization analysis of teleseismic data has been used to determine the XKS(SKS,SKKS,and PKS)fast polarization directions and delay times between fast and slow shear waves for 59 seismic stations of both temporary and permanent broadband seismograph networks deployed in the eastern Himalayan syntaxis(EHS)and surrounding regions.The analysis employed both the grid searching method of the minimum tangential energy and stacking analysis methods to develop an image of upper mantle anisotropy in the EHS and surrounding regions using the newly obtained shear wave splitting parameters and previously published results.The fast polarization directions are oriented along a NE-SW azimuth in the EHS.However,within the surrounding regions,the fast directions show a clockwise rotation pattern around the EHS from NE-SW,to E-W,to NW-SE,and then to N-S.In the EHS and surrounding regions,the fast directions of seismic anisotropy determined using shear wave splitting analysis correlate with surficial geological features including major sutures and faults and with the surface deformation fields derived from global positioning system(GPS)data.The coincidence between structural features in the crust,surface deformation fields and mantle anisotropy suggests that the deformation in the crust and lithospheric mantle is mechanically coupled.In the EHS,the coherence between the fast directions and the NE direction of the subduction of the Indian Plate beneath the Tibetan Plateau suggests that the lithospheric deformation is caused mainly by subduction.In the regions surrounding the EHS,we speculate that a westward retreat of the Burma slab could contribute to the curved anisotropy pattern.The Tibetan Plateau is acted upon by a NE-trending force due to the subduction of the Indian Plate,and also affected by a westward drag force due to the westward retreat produced by the eastward subduction of the Burma slab.The two forces contribute to a curved lithospheric deformation that results in the alignment of the upper mantle peridotite lattice parallel to the deformation direction,and thus generates a curved pattern of fast directions around the EHS. | CHANG LiJun WANG ChunYong DING ZhiFeng YOU HuiChuan LOU Hai SHAO CuiRu | 2015 | Science China Earth Sciences2015，58，10： | 16 |
| 8 | Variations of shear wave splitting in the 2013 Lushan Ms7.0 earthquake region显示文摘In this paper, variations of shear wave splitting in the 2013 Lushan Ms7.0 earthquake sequence were studied. By analyzing shear wave particle motion of local events in the shear wave window, the fast polarization directions and the delay time between fast and slow shear waves were derived from seismic recordings at eight stations on the southern segment of the Longmenshan fault zone. In the study region, the fast polarization directions show partition characteristics from south to north. And the systematic changes of the time delays between two split shear waves were also observed. As for spatial distribution, the NE fast polarization directions are consistent with the Longmenshan fault strike in the south of focal region, whereas the NW fast direction is parallel to the direction of regional principal compressive stress in the north of focal region. Stations BAX and TQU are respectively located on the Central and Front-range faults, and because of the direct influence of these faults, the fast directions at both stations show particularity. In time domain, after the main shock, the delay times at stations increased rapidly, and decreased after a period of time. Shear-wave splitting was caused mostly by stress-aligned microcracks in rock below the stations. The results demonstrate changes of local stress field during the main shock and the aftershocks. The stress on the Lushan Ms7.0 earthquake region increased after the main shock, with the stress release caused by the aftershocks and the stress reduced in the late stage. | CHANG LiJun DING ZhiFeng WANG ChunYong | 2014 | Science China Earth Sciences2014，57，9： | 12 |
| 9 | Assessing the numbers of SNPs needed to establish molecular IDs and characterize the genetic diversityof soybean cultivars derived from Tokachi nagaha显示文摘The development of a core set of SNP molecular markers that could be widely used in soybean genetic research would greatly facilitate research into the genetic diversity of soybean.We conducted an analysis of Tokachi nagaha and 137 of its descendant soybean cultivars using 4044 SNP markers with the goal of determining the appropriate number of single-nucleotide polymorphisms(SNPs)needed to construct unambiguous molecular IDs and characterize genetic diversity based on a genetic distance matrix correlation method.When the number of SNPs was held constant,the number of accession pairs that could be distinguished increased as the polymorphism informative content(PIC)value of the SNPs increased.A core panel of 20 selected SNPs from 11 linkage groups with a mean PIC value of 0.3703 and a range of 0.3640–0.3749 was able to identify almost all of the accession pairs in our study[9445 pairs(99.92%)].The eight accession pairs that could not be identified with this core SNP set all originated from the same province and some of them had the same parental cultivars.The molecular IDs of the 138 accessions were constructed using the core 20 SNPs.It is known that both the number of SNPs and PIC values should be considered when SNPs are selected for use in the analysis of genetic diversity.In this study,when the PIC value was 0.3460,the correlation coefficient between the genetic distance matrices associated with a panel of 200 SNPs and the total population was>0.800,indicating satisfactory correlation.Our high-accuracy,high-resolution core SNP panel for germplasm fingerprinting and our findings about assessing genetic diversity will likely markedly improve the management and utilization efficiency of soybean germplasm resources. | Zhangxiong Liu Jun Li Xuhong Fan Nang Myint Phyu Sin Htwe Shuming Wang Wen Huang Jiyu Yang Lili Xing Lijun Chen Yinghui Li Rongxia Guan Ruzhen Chang Dechun Wang Lijuan Qiu | 2017 | The Crop Journal2017，5，4： | 10 |
| 10 | The spectrum for large sets of pure directed triple systems显示文摘An LPDTS(υ) is a collection of 3(υ - 2) disjoint pure directed triple systems on the same set of υ elements. It is showed in Tian's doctoral thesis that there exists an LPDTS(υ) for υ≡ 0,4 (mod 6), υ≥ 4. In this paper, we establish the existence of an LPDTS(υ) for υ≡ 1, 3 (mod 6), υ> 3. Thus the spectrum for LPDTS(υ) is completely determined to be the set {υ:υ≡0, 1 (mod 3),υ≥4}. | ZHOU Junling, CHANG Yanxun & Jl Lijun Institute of Mathematics, Beijing Jiaotong University, Beijing 100044, China Department of Mathematics, Suzhou University, Suzhou 215006, China | 2006 | Science China Mathematics2006，49，8： | 9 |
| 11 | Measurement of nonuniform temperature distribution by combining line-of-sight TDLAS with regularization methods显示文摘Regularization methods were combined with line-of-sight tunable diode laser absorption spectroscopy(TDLAS)to measure nonuniform temperature distribution.Relying on measurements of 12 absorption transitions of water vapor from 1300 nm to 1350 nm,the temperature probability distribution of nonuniform temperature distribution,for which a parabolic temperature profile is selected as an example in this paper,was retrieved by making the use of regularization methods.To examine the effectiveness of regularization methods,truncated singular value decomposition(TSVD),Tikhonov regularization and a revised Tikhonov regularization method were implemented to retrieve the temperature probability distribution.The results derived by using the three regularization methods were compared with that by using constrained linear least-square fitting.The results show that regularization methods not only generate closer temperature probability distributions to the original,but also are less sensitive to measurement noise.Particularly,the revised Tikhonov regularization method generate solutions in better agreement with the original ones than those obtained by using TSVD and Tikhonov regularization methods.The results obtained in this work can enrich the temperature distribution information,which is expected to play a more important role in combustion diagnosis. | LIU Chang XU Lijun CAO Zhang | 2014 | Instrumentation2014，1，3： | 5 |
| 12 | Upper crustal velocity and seismogenic environment of the M7.0 Jiuzhaigou earthquake region in Sichuan, China显示文摘On August 8,2017,a magnitude 7.0 earthquake occurred in Jiuzhaigou County,Sichuan Province,China.The deep seismogenic environment and potential seismic risk in the eastern margin of Tibetan Plateau have once again attracted the close attention of seismologists and scholars at home and abroad.The post-earthquake scientific investigation could not identify noticeable surface rupture zones in the affected area;the complex tectonic background and the reason(s)for the frequent seismicity in the Jiuzhaigou earthquake region are unclear.In order to reveal the characteristics of the deep medium and the seismogenic environment of the M7.0 Jiuzhaigou earthquake region,and to interpret the tectonic background and genesis of the seismicity comprehensively,in this paper,we have reviewed all available observation data recorded by the regional digital seismic networks and large-scale,dense mobile seismic array(China Array)for the northern section of the North-South Seismic Belt around Jiuzhaigou earthquake region.Using double-difference seismic tomography method to invert the three-dimensional P-wave velocity structure characteristics of the upper crust around the Jiuzhaigou earthquake region,we have analyzed and discussed such scientific questions as the relationship between the velocity structure characteristics and seismicity in the Jiuzhaigou earthquake region,its deep tectonic environment,and the ongoing seismic risk in this region.We report that:the P-wave velocity structure of the upper crust around the Jiuzhaigoug earthquake region exhibits obvious lateral inhomogeneity;the distribution characteristics of the shallow P-wave velocity structure are closely related to surface geological structure and formation lithology;the M7.0 Jiuzhaigou earthquake sequence is closely related to the velocity structure of the upper crust;the mainshock of the M7.0 earthquake occurred in the upper crust;the inhomogeneous variation of the velocity structure of the Jiuzhaigou earthquake area and its surrounding medium appears to be the deep structural factor controlling the spatial distribution of the mainshock and its sequence.The 3D P-wave velocity structure also suggests that the crustal low-velocity layer of northeastern SGB(Songpan-GarzêBlock)stretches into MSM(Minshan Mountain),and migrates to the northeast,but the tendency to emerge as a shallow layer is impeded by the high-velocity zone of Nanping Nappe tectonics and the Bikou Block.Our results reveal an uneven distribution of high-and low-velocity structures around the Tazang segment of the East Kunlun fault zone.Given that the rupture caused by the Jiuzhaigou earthquake has enhanced the stress fields at both ends of the seismogenic fault,it is very important to stay vigilant to possible seismic hazards in the large seismic gap at the Maqu-Maqên segment of the East Kunlun fault zone. | DaHu Li ZhiFeng Ding Yan Zhan PingPing Wu LiJun Chang XiangYu Sun | 2021 | Earth and Planetary Physics2021，5，4： | 4 |
| 13 | Loading direction dependent mechanical behavior of graphene under shear strain显示文摘The mechanical behavior of graphene under in-plane shear is studied using molecular dynamics simulations.We show that the shear behavior of chiral graphene is dependent on the loading direction due to its structural asymmetry.The maximum shear failure strain of graphene in one direction may be 1.7 times higher than that in the opposite direction.We discuss also the influence of the cut-off parameters on the calculations.Our findings are useful for the understanding of mechanical behavior of graphene and the potential applications of graphene in nanodevices. | YI LiJun CHANG TienChong | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，6： | 4 |
| 14 | Protective effects of effective ingredients of Danshen (Radix Salviae Miltiorrhizae)and Honghua (Flos Carthami)compatibility after rat hippocampal neurons induced by hypoxia injury显示文摘OBJECTIVE: To investigate the effective ingredients of Danshen(Radix Salviae Miltiorrhizae) and Honghua(Flos Carthami)(Danhong) on protective properties towards neonatal rat hippocampal neurons under hypoxia condition.METHODS: Primary culture of neonatal rat hippocampal neurons was used to model hypoxia damage on the hippocampus. Methyl thiazolyl tetrazolium(MTT) assay and preliminary experiments were conducted to identify the four effective ingredients of Danhong, along with the injection of positive drug onto hippocampal neurons at a non-toxic dosage level. The cultured cells were randomly divided into 12 groups: the normal group, model group,positive drug control group and nine compatibility groups of the four effective ingredients. Different test methods were applied to determine lactate dehydrogenasein(LDH), total superoxide dismutase(T-SOD), malondialdehyde(MDA), 6-keto prostaglandin F_(la)(6-keto-PGF_(1 a)), thromboxane B_2(TXB_2),mitochondrial membrane potential(MMP), free calcium ions concentration([Ca^(2 +)]i) and early onsetcell apoptosis.RESULTS: Different compatibility groups could inhibit the content of LDH and intracellular calcium overload, increase activity in T-SOD, decrease level of MDA and TXB2, improve level of 6-keto-PGF1 aand MMP, and prevent the early onset cell apoptosis.CONCLUSION: The compatibility of four effective ingredients of Danhong had protective effect toward hippocampi hypoxia. The mechanism might be related to inhibit oxidative stress damage and cell apoptosis, resist thrombosis, and reduce the intracellular calcium ion of overload. | Yu Li Wan Haofang Jin Weifeng Yang Jiehong Li Chang Dai Liuling Ge Lijun Zhou Huifen Wan Haitong He Yu | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 4 |
| 15 | Halide Homogenization for High-Performance Blue Perovskite Electroluminescence显示文摘Metal halide perovskite light-emitting diodes(LEDs)have achieved great progress in recent years.However,bright and spectrally stable blue perovskite LED remains a significant challenge.Three-dimensional mixed-halide perovskites have potential to achieve high brightness electroluminescence,but their emission spectra are unstable as a result of halide phase separation.Here,we reveal that there is already heterogeneous distribution of halides in the as-deposited perovskite films,which can trace back to the nonuniform mixture of halides in the precursors.By simply introducing cationic surfactants to improve the homogeneity of the halides in the precursor solution,we can overcome the phase segregation issue and obtain spectrally stable single-phase blueemitting perovskites.We demonstrate efficient blue perovskite LEDs with high brightness,e.g.,luminous efficacy of 4.7,2.9,and 0.4 lmW^(-1) and luminance of over 37,000,9,300,and 1,300 cdm^(-2) for sky blue,blue,and deep blue with Commission Internationale de l’Eclairage(CIE)coordinates of(0.068,0.268),(0.091,0.165),and(0.129,0.061),respectively,suggesting real promise of perovskites for LED applications. | Lu Cheng Chang Yi Yunfang Tong Lin Zhu Gunnar Kusch Xiaoyu Wang Xinjiang Wang Tao Jiang Hao Zhang Ju Zhang Chen Xue Hong Chen Wenjie Xu Dawei Liu Rachel AOliver Richard HFriend Lijun Zhang Nana Wang Wei Huang Jianpu Wang | 2020 | Research2020，，1： | 4 |
| 16 | MiR-22 as a metabolic silencer and liver tumor suppressor显示文摘With obesity rate consistently increasing,a strong relationship between obesity and fatty liver disease has been discovered.More than 90%of bariatric surgery patients also have non-alcoholic fatty liver diseases(NAFLDs).NAFLD and non-alcoholic steatohepatitis(NASH),which are the hepatic manifesta-tions of metabolic syndrome,can lead to liver carcinogenesis.Unfortunately,there is no effective medicine that can be used to treat NASH or liver cancer.Thus,it is critically important to understand the mechanism underlying the development of these diseases.Extensive evidence suggests that microRNA 22(miR-22)can be a diagnostic marker for liver diseases as well as a treatment target.This review paper focuses on the roles of miR-22 in metabolism,steatosis,and liver carcinogenesis.Literature search is limited based on the publications included in the PubMed database in the recent 10 years. | Lijun Wang Yu-Shiuan Wang Eko Mugiyanto Wei-Chiao Chang Yu-Jui Yvonne Wan | 2020 | Liver Research2020，4，2： | 3 |
| 17 | Upper crustal anisotropy observed around the Longmenshan fault in the 2013 M_S7.0 Lushan earthquake region显示文摘Based on the shear wave splitting analysis of the seismic recordings at 17 temporary stations and three permanent stations, we measured the shear wave splitting parameters(i.e., the polarization direction of fast shear wave and the time delay of slow wave) to perform a systematic analysis of the crustal seismic anisotropy around the Longmenshan fault in the 2013 M_S7.0 Lushan earthquake region. We observed apparent spatio-temporal characteristics in the shear wave splitting parameters. The spatial distribution of fast polarization directions showed a clear partitioning in the characteristics from northwest to southeast in the focal region,which changed from NW-SE to NE-SW. In the northwest of the focal region, the fast polarization direction was oriented to NW-SE, which was parallel to the maximum horizontal compressive stress direction. However, the NE-SW fast polarization direction in the southeast of the focal region was parallel to the Longmenshan fault strike. For station BAX on the Central fault in the middle of the focal region, the distribution of fast polarization directions showed a bimodal pattern, with one dominant in the NE-SW direction and the other in the NW-SE direction. With regard to the temporal variation, the time delays were large in the initial stage after the mainshock but then gradually decreased over time and tended to be stable in the later period. This indicated that stress in the focal region increased to a maximum when the main shock occurred, with the stress release caused by the mainshock and aftershock activity, and the stress gradually decreased after a period of time. The scatter of fast polarization directions was large after the main shock, but over time the scatter gradually decreased, indicating that the Lushan earthquake caused a large perturbation in the local stress field. As the stress gradually decreased and was adjusted by the aftershock activity, the perturbation gradually weakened. | Lijun Chang Zhifeng Ding Chunyong Wang | 2018 | Earthquake Science2018，31，4： | 2 |
| 18 | Continuous synthesis of ultra-fine fiber for wearable mechanoluminescent textile显示文摘Continuous mechanoluminescence(ML)fibers and fiber-woven textiles have the potential to serve as new wearable devices for sensors,healthcare,human-computer interfacing,and Internet of Things.Considering the demands on wearability and adaptability for the ML textiles,it is essential to realize the continuous synthesis of fiber,while maintaining a desired small diameter.Here,we develop a novel adhere-coating method to fabricate ML composite fiber,consisting of a thin polyurethane(PU)core and ZnS:Cu/polydimethylsiloxane(PDMS)shell,with the outer diameter of 120μm.By diluting PDMS to tune the thickness of liquid coating layer,droplets formation has been effectively prevented.The composite fiber exhibits a smooth surface structure and superior ML performances,including high brightness,excellent flexibility,and stability.In addition,a weft knitting textile fabricated by the continuous ML fiber can be easily delighted by manually stretching,and the ML fibers can emit visible signals upon human motion stimuli when woven into commercial cloth.Such continuous ultra-fine ML fibers are promising as wearable sensing devices for human motion detection and human-machine interactions. | Shulong Chang Yuan Deng Na Li Lijun Wang Chong-Xin Shan Lin Dong | 2023 | Nano Research2023，16，7： | 2 |
| 19 | Recent progress in tumor photodynamic immunotherapy显示文摘Photodynamic therapy(PDT)is a promising alternative approach for effective cancer treatment,which can directly destroy local tumor cells due to the generation of cytotoxic singlet oxygen and reactive oxygen species(ROS)in the tumor cells.Intriguingly,PDT-mediated cell death is also associated with anti-tumor immune response.Howeve r,immunosuppre s sion of tumor microe nvironment is able to limit the immune response induced by PDT,it is therefore necessary to combine with immunocheckpoint inhibitor and immunoadjuvant for synergistic treatment of tumors.Herein,the recent advances of PDT,immunotherapy,and photodynamic immunotherapy are reviewed. | Lijun Shen Tianjiao Zhou Yatong Fan Xin Chang Yi Wang Jianguo Sun Lei Xing Hulin Jiang | 2020 | Chinese Chemical Letters2020，31，7： | 2 |
| 20 | Progress in drug delivery system for fibrosis therapy显示文摘Fibrosis is a necessary process in the progression of chronic disease to cirrhosis or even cancer,which is a serious disease threatening human health.Recent studies have shown that the early treatment of fibrosis is turning point and particularly important.Therefore,how to reverse fibrosis has become the focus and research hotspot in recent years.So far,the considerable progress has been made in the development of effective anti-fibrosis drugs and targeted drug delivery.Moreover,the existing research results will lay the foundation for more breakthrough delivery systems to achieve better anti-fibrosis effects.Herein,this review summaries anti-fibrosis delivery systems focused on three major organ fibrotic diseases such as liver,pulmonary,and renal fibrosis accompanied by the elaboration of relevant pathological mechanisms,which will provide inspiration and guidance for the design of fibrosis drugs and therapeutic systems in the future. | Lei Xing Xin Chang Lijun Shen Chenglu Zhang Yatong Fan Chongsu Cho Zhiqi Zhang Hulin Jiang | 2021 | Asian Journal of Pharmaceutical Sciences2021，16，1： | 2 |
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