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| 1 | Fructus Broussonetae extract improves cognitive function and endoplasmic reticulum stress in Alzheimer's disease models显示文摘This study investigated the effects and possible targets of Fructus Broussonetiae extract,a traditional Chinese medicinal herb,on a model of Alzheimer's disease induced by beta-amyloid peptide 25-35 and D-galactose.The results revealed that intragastric administration of Fructus Broussonetiae significantly increased the expression of immunoglobulin-binding protein,a key factor in the endoplasmic reticulum stress-signaling pathway in rat hippocampus.In contrast,the treatment significantly decreased expression levels of PKR-like endoplasmic reticulum kinase and C/EBP homologous protein,and substantially improved learning,memory and spatial recognition dysfunction in rats.This evidence indicates that Fructus Broussonetiae extract improves spatial learning and memory abilities in rats by affecting the regulation of hippocampal endoplasmic reticulum stress and activation of the apoptosis pathway. | Yinghong Li Li Hu Zhengzhi Wu Zhiling Yu Meiqun Cao Kehuan Sun Yu Jin Anmin Wu Andrew CJ Huang | 2011 | Neural Regeneration Research2011，6，30： | 7 |
| 2 | 肠道微生态失调与高血压的关系显示文摘新出现的证据表明,肠道菌群是维持生理动态平衡的关键,该研究旨在验证微生态失衡的肠道菌群与高血压相关这一假设,因为遗传、环境和膳食因素对肠道菌群和血压有很大影响。方法:从2种高血压模型大鼠和一个小队列患者人群的粪便样本中提取细菌DNA,用于细菌基因组的分析. | 刘莉 叶鹏 Yang T Santisteban MM Rodriguez V Li E Ahmari N Carvajal JM Zadeh M Gong M Qi Y Zubcevic J Sahay B Pepine CJ Raizada MK Mohamadzadeh M | 2015 | 中华高血压杂志2015，23，5： | 4 |
| 3 | 母体卡托普利治疗可持续改善肠-脑轴并减轻雄性后代的高血压显示文摘母胎相互作用在后代的远期健康及跨代高血压的发生中发挥作用。然而,目前对于母体对后代肠道及肠道微生物环境的影响在后代高血压控制中的作用仍知之甚少。此研究旨在检验母体对后代肠-脑轴产生影响,继而影响后代高血压发生这一假设。本研究选用卡托普利进行实验,卡托普利是一种具有抗菌特性的血管紧张素转换酶抑制剂。在整个怀孕和哺乳期间,对怀孕的自发性高血压母鼠和正常血压的母鼠(WKY组)给予卡托普利水[100 mg/(kg·d)]或无菌水。 | 周卫(译) 叶鹏(校) Li H Yang T Richards EM Pepine CJ Raizada MK | 2020 | 中华高血压杂志2020，28，5： | 3 |
| 4 | Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis 显示文摘 | Li H Zhu H Xu CJ | 1998 | Cell1998，94，4： | 2 |
| 5 | A hypothesis:adiponectin mediates anti-atherosclerosis via adventitia-AMPK-iNOS pathway显示文摘 | Cai XJ Li CJ Chen L | 2008 | Med Hypotheses2008，70，5： | 1 |
| 6 | Evolution of H9N2 influenza viruses from domestic poultry in Mainland China显示文摘 | LI CJ YU KZ TIAN GB | 2005 | Virology2005，340，1： | 1 |
| 7 | Dissemination of CTX- M type β- lactamases in Enterobacteriaceae isolates in the People's Republic of China显示文摘 | Mundaya CJ Xiong J Li C | 2004 | Int J Antimicrob Agents2004，23，： | 1 |
| 8 | Transgenic mice and knockout mutants i n the study of oxidative stress in brain injury显示文摘 | Chan PH Epstein CJ Li Y | 1995 | J Neurotrauma1995，12，5： | 1 |
| 9 | Dissemination of CTX-M type β-lactamases in Enterobacteriaceae isolates in the People's Republic of China显示文摘 | Munday CJ Xiong J Li C | 2004 | Int J Antimicrob Agents2004，23，2： | 1 |
| 10 | Effects of intracoronary autologous bone marrow cells on left ventricular function in acute myocardial infarction: a systematic review and recta- analysis for randomized controlled trials显示文摘 | Kang S Yang YJ Li CJ | 2008 | Coron Artery Dis2008，19，5： | 1 |
| 11 | Decreased tobacco-specific nitrosamines by microbial treatment with Bacillus amyloliquefaciens DA9 during the Air-Curing process of burley tobacco 显示文摘 | Wei XT Deng XW Cai DB Ji ZX Wang CJ Yu J Li JP and Chen SW | 2014 | J Agric Food Chem2014，62，12： | 1 |
| 12 | Potent induction of apoptosis by beta-lapachone in human multiple myeloma cill ines and patient cells显示文摘 | Li Y Li CJ Yu D | 2000 | Mol Med2000，，12： | 1 |
| 13 | Molecular mechanisms of angiotensin II stimulation on aquaporin - 2 expression and trafficking 显示文摘 | Li C Wang W Rivard CJ | 2011 | Am J Physiol Renal Physiol2011，300，5： | 1 |
| 14 | Effects of TiO2 mating on mi- crostructure and mechanical properties of magnesium matrix compos- ite reinforced with Mg-B2Osw 显示文摘 | Li JG Xia CJ Zhang YJ | 2012 | Materials and Design2012，39，： | 1 |
| 15 | Regulation in S phase by E2F显示文摘 | Pardee AB Li CJ Reddy GP | 2004 | Cell Cycle2004，3，9： | 1 |
| 16 | Inflammatory cell adhesion molecules ischemic cerebrovaseular disease显示文摘 | Frijns CJ Kappelle LI | 2002 | Stroke2002，33，8： | 1 |
| 17 | Expression of homeobox genes in cervical cancer 显示文摘 | Huang CJ Chook B | 2002 | Gynecol Oncol2002，84，2： | 1 |
| 18 | Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma 显示文摘 | Li AC Binder CJ Gutierrez A | 2004 | J Clin Invest2004，114，11： | 1 |
| 19 | Abdominal aorticcalcific deposits are an important predictor of vascularmorbidity and mortality显示文摘 | Wilson PW Kauppila LI O'Donnell CJ | | 0，，11： | 1 |
| 20 | Chemerin expression in Chinese pregnant women with and without gestational diabetes mellitus显示文摘 | Li XM Ji H Li CJ | 2015 | Ann Endocrinol(Paris)2015，76，1： | 1 |
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