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| 1 | Nab-paclitaxel(abraxane)-based chemotherapy to treat elderly patients with advanced non-small-cell lung cancer:a single center,randomized and open-label clinical trial显示文摘Background:The purpose of this study is to evaluate the clinical efficacy and safety of abraxane-based chemotherapy with/without nedaplatin in elderly patients with non-small-cell lung cancer(NSCLC).Materials and methods:From October 2009 to January 2013,48 elderly patients(>65 years) with NSCLC were investigated in this clinical trial.The patients were randomized and equally allocated into arms A and AP:(A) abraxane(130 mg/m^2,days 1,8);(B) abraxane + nedaplatin(20 mg/m^2 days 1-3,q3w).The parameters of objective response rate(ORR),disease control rate(DCR),progression-free survival(PFS),overall survival(OS) and side effects were evaluated between two arms.Results:Over 80%of the patients completed four cycles of chemotherapy.The total ORR was 21.3%,DCR was 55.3%,PFS 4.5 months and OS 12.6 months.No significant difference was found between arms A and AP in terms of ORR(16.7%vs.26.1%,P=0.665) or DCR(55.3%vs.56.5%,P=0.871).The median PFS in arm A was 3.3 months[25-75%confidence interval(CI):3.1-7.2]and 5.5 months(25-75%CI:3.2-7.0) in arm AP with no statistical significance(P=0.640).The median OS in arm A was 12.6 months(25-75%CI:5.7-26.2) and 15.1 months(25-75%CI:6.4-35.3) in arm AP with no statistical significance(P=0.770).The side effects were mainly grade 1-2.The incidence of grade 3-4 toxicities was 29.1%in arm A and 62.5%in arm AP with a statistical significance(P=0.020).Conclusions:Compared with combined therapy,abraxane alone chemotherapy was beneficial for elderly NSCLC patients with better tolerability and less adverse events,whereas did not significantly differ in terms of ORR,DCR,PFS or OS. | Hanrui Chen Xuewu Huang Shutang Wang Xinting Zheng Jietao Lin Peng Li Lizhu Lin | 2015 | Chinese Journal of Cancer Research2015，27，2： | 12 |
| 2 | PagGRF12a interacts with PagGIF1b to regulate secondary xylem development through modulating PagXND1a expression in Populus alba×P.glandulosa显示文摘Growth-regulating factors(GRFs)are important regulators of plant development and growth,but their possible roles in xylem development in woody plants remain unclear.Here,we report that Populus alba×Papulus glandulosa PagGRF12a negatively regulates xylem development in poplar.PagGRF12a is expressed in vascular tissues.Compared to non-transgenic control plants,transgenic poplar plants overexpressing PagGRF12a exhibited reduced xylem width and plants with repressed expression of PagGRF12a exhibited increased xylem width.Xylem NAC domain 1(XND1)encodes a NAC domain transcription factor that regulates xylem development and transcriptional analyses revealed that PagXND1a is highly upregulated in PagGRF12a-overexpressing plants and downregulated in PagGRF12a-suppressed plants,indicating that PagGRF12a may regulate xylem development through PagXND1a.Transient transcriptional assays and chromatin immunoprecipitation-polymerase chain reaction assays confirmed that PagGRF12a directly upregulates PagXND1a.In addition,PagGRF12a interacts with the GRF-Interacting Factor(GIF)PagGIF1b,and this interaction enhances the effects of PagGRF12a on PagXND1a.Our results indicate that PagGRF12a inhibits xylem development by upregulating the expression of PagXND1a. | Jinnan Wang Houjun Zhou Yanqiu Zhao Cheng Jiang Jihong Li Fang Tang Yingli Liu Shutang Zhao Jianjun Hu Xueqin Song MengZhu Lu | 2021 | Journal of Integrative Plant Biology2021，63，10： | 3 |
| 3 | The alkaline/surfactant/polymer pilot performance of saertu,west central,Daqing oilfield显示文摘 | Gao Shutang Li Huabin Yang Zhenyu | 1996 | Soc Petrol Engrs Reserv Engng1996，11，3： | 1 |
| 4 | A novel image encryption scheme based on spatial chaos map 显示文摘 | SUN Fuyan LIU Shutang LI Zhongqin | 2008 | Chaos Solitons & Fractals2008，38，3： | 1 |
| 5 | A novel im- age encryption scheme based on spatial chaos map显示文摘 | SUN FUYAN LIU SHUTANG LI ZHONGQING | 2008 | Chaos Soli- tons & Fractals2008，38，3： | 1 |
| 6 | Laboratory Investigation of Combination of Alkaline-Surfactant-Polymer Technology for Daqing EOR 显示文摘 | LI HUABIN LI HONGFU | 1995 | SPE Reservoir Engineering1995，10，3： | 1 |
| 7 | A Novel Image Encryption Scheme Based on Spatial Chaos Map显示文摘 | Sun Fuyan Liu Shutang Li Zhongqin | 2008 | Chaos Solitons & Fractals2008，38，3： | 1 |
| 8 | Synthesis and characterization of CdS nanoparticles in the presence of oleic acid as solvent and stabilizer 显示文摘 | Li Na Zhang Xiaoling Chen Shutang | 2011 | Journal of Physics and Chemistry of Solids2011，72，： | 1 |
| 9 | An alkaline/surfactant/polymer pilot performance of the west central Saertu,Daqing oilfield显示文摘 | Gao Shutang Li Huabin Yang Zhenyu | 1996 | Soc Petrol Engrs Reserv Engng1996，，8： | 1 |
| 10 | QUENCH IN STABILIZATION OF Cu-Zn-Al ALLOY显示文摘QUENCHINSTABILIZATIONOFCuZnAlALLOY①PengKun,TanShusong,LiShutangDepartmentofMaterialsScienceandEnginering,CentralSouthUniver... | Peng, Kun Tan, Shusong Li, Shutang Chung, C.Y. Lan, C.W.H. | 1997 | 中国有色金属学会会刊:英文版1997，7，3： | 1 |
| 11 | The alkaline/surfactant/polymer pilot performance of Saertu,west central,Daqing oilfield显示文摘 | Gao Shutang Li Huabin Yang Zhenyu | 1996 | Soc Petrol Engrs Reserv Engng1996，，2： | 1 |
| 12 | Laboratory Investigation of Combination of Alkali/Surfactant/Polymer Technology for Daqing EOR显示文摘 | GAO Shutang LI Huabin LI Hongfu | 1995 | SPE Reservoir Engineering1995，10，3： | 1 |
| 13 | Adding power of artificial intelligence to situational awareness of large interconnections dominated by inverter‐based resources显示文摘Large‐scale power systems exhibit more complex dynamics due to the increasing inte-gration of inverter‐based resources(IBRs).Therefore,there is an urgent need to enhance the situational awareness capability for better monitoring and control of power grids dominated by IBRs.As a pioneering Wide‐Area Measurement System,FNET/GridEye has developed and implemented various advanced applications based on the collected synchrophasor measurements to enhance the situational awareness capability of large‐scale power grids.This study provides an overview of the latest progress of FNET/GridEye.The sensors,communication,and data servers are upgraded to handle ultra‐high density synchrophasor and point‐on‐wave data to monitor system dynamics with more details.More importantly,several artificial intelligence(AI)‐based advanced appli-cations are introduced,including AI‐based inertia estimation,AI‐based disturbance size and location estimation,AI‐based system stability assessment,and AI‐based data authentication. | Lin Zhu Yinfeng Zhao Yi Cui Shutang You Wenpeng Yu Shengyuan Liu He Yin Chang Chen Yuru Wu Wei Qiu Mirka Mandich Hongyu Li Adedasola Ademola Chengwen Zhang Chujie Zeng Xinlan Jia Weikang Wang Haoyu Yuan Huaiguang Jiang Jin Tan Yilu Liu | 2021 | High Voltage2021，6，6： | 0 |
| 14 | CHAOS-BASED SECURE COMMUNICATIONS显示文摘With the massive increase of wirelessly connected devices and the rapid development of the Internet, information is transmitted more and more frequently. Since the information transmissions over these networks are greatly threatened not only by the imperfection of channels but also by the potential attackers or eavesdroppers, security and reliability become some of the crucial requirements for our future networks. Due to the complex dynamic behavior, ergodicity, wide spectrum and sensitivity to initial values, chaos signals show most required attributes of good cryptosystems and great potentials in optical fiber communications for desirable spatial accuracy and distance. In this context, it has become imperative to investigate and apply chaos theories to solve emerging secure communication problems in various networks. This includes leveraging chaos systems and signals to address a wide range of secure communication challenges in optical fiber communications, chaos cipher, image encryption, etc. | Xiaofeng Liao Shutang Liu Chengqing Li Yulong Zou | 2020 | China Communications2020，17，5： | 0 |
| 15 | Artificial Shiro formation of Tricholoma matsutake显示文摘One type of soil collected from Maoer-shan in Heilongjiang Province,China was selected to induce hyphal growth of Tricholoma matsutake by a soil screening ex-periment.It was confirmed that hyphal growth of all the tested T.matsutake isolates was significantly stimulated in soil by supplemented with 0.5%~2.0%olive oil.The ag-gregation of hyphae and soil resembled natural Shiro.The biomass of hyphae in the soil increases with increasing olive oil concentrations.Moreover,seedlings of Pinus den-siflora grew well in the soil containing 0.5%~1.0%olive oil and were also successfully infected by T.matsutake isolate A in the soil containing 1.0%olive oil.This study estab-lished a culture system of artificial Shiro formation and also provided a premise for formulation of culture substratum for fruit body formation of T.matsutake. | LUN Zhiming LI Yuhua XING Shutang Vaario Lumin | 2006 | Frontiers in Biology2006，1，3： | 0 |
| 16 | Trade-offs between the accumulation of cuticular wax and jasmonic acid-mediated herbivory resistance in maize显示文摘Plants have evolved complex physical and chemical defense systems that allow them to withstand herbivory infestation.Composed of a complex mixture of very-long-chain fatty acids(VLCFAs)and their derivatives,cuticular wax constitutes the first physical line of defense against herbivores.Here,we report the function of Glossy 8(ZmGL8),which encodes a 3-ketoacyl reductase belonging to the fatty acid elongase complex,in orchestrating wax production and jasmonic acid(JA)-mediated defenses against herbivores in maize(Zea mays).The mutation of GL8 enhanced chemical defenses by activating the JA-dependent pathway.We observed a trade-off between wax accumulation and JA levels across maize glossy mutants and 24 globally collected maize inbred lines.In addition,we demonstrated that mutants defective in cuticular wax biosynthesis in Arabidopsis thaliana and maize exhibit enhanced chemical defenses.Comprehensive transcriptomic and lipidomic analyses indicated that the gl8 mutant confers chemical resistance to herbivores by remodeling VLCFA-related lipid metabolism and subsequent JA biosynthesis and signaling.These results suggest that VLCFA-related lipid metabolism has a critical role in regulating the trade-offs between cuticular wax and JA-mediated chemical defenses. | Jiong Liu Lu Li Zhilong Xiong Christelle AMRobert Baozhu Li Shan He Wenjie Chen Jiasheng Bi Guanqing Zhai Siyi Guo Hui Zhang Jieping Li Shutang Zhou Xi Zhang Chun‐Peng Song | 2024 | Journal of Integrative Plant Biology2024，66，1： | 0 |
| 17 | Surface protection method for the magnetic core using covalent organic framework shells and its application in As(Ⅲ)depth removal from acid wastewater显示文摘Fe_(3)O_(4)-based materials are widely used for magnetic separation from wastewater.However,they often suffer from Fe-leaching behavior under acidic conditions,decreasing their ac-tivity and limiting sustainable practical applications.In this study,covalent organic frame-works(COFs)were used as the shell to protect the Fe_(3)O_(4) core,and the Fe_(3)O_(4)@COF core-shell composites were synthesized for As(Ⅲ)removal from acid wastewater.The imine-linked COFs can in situ grow on the surface of the Fe_(3)O_(4) core layer by layer with[COFs/Fe_(3)O_(4)]mol ratio of up to 2∶1.The Fe-leaching behavior was weakened over a wide pH range of 1-13.Moreover,such composites keep their magnetic characteristic,making them favorable for nanomaterial separation.As(Ⅲ)batch adsorption experiments results indicated that,when COFs are used as the shell for the Fe_(3)O_(4) core,a balance between As(Ⅲ)removal efficiencies and the thickness of the COF shell exists.Higher As(Ⅲ)removal efficiencies are obtained when the[COFs/Fe_(3)O_(4)]mol ratios were<1.5∶1,but thicker COF shells were not beneficial for As(Ⅲ)removal.Such composites also exhibited better As(Ⅲ)removal performances in the pH range of 1-7.Over a wide pH range,the zeta potential of Fe_(3)O_(4)@COF core-shell compos-ites becomes more positive,which benefits the capture of negative arsenic ions.In addition,thinner surface COFs were favorable for mass transfer and facilitating the reaction of Fe and As elements.Our study highlights the promise of using COFs in nanomaterial surface protection and achieving As(Ⅲ)depth removal under acidic conditions. | Wenjun Huang Haomiao Xu Xiaoshuang Liu Longlong Wang Shutang Li Leipeng Ji Zan Qu Naiqiang Yan | 2022 | Journal of Environmental Sciences2022，34，5： | 0 |
| 18 | SHAPE MEMORY EFFECT OF A TUNGSTEN TAILINGS MICROCRYSTALLINE GLASS显示文摘SHAPEMEMORYEFFECTOFATUNGSTENTAILINGSMICROCRYSTALLINEGLASS①SunXiaohua,LiShutang,WangMingpu,CaoXianliangDepartmentofMaterialsSc... | Sun, Xiaohua Li, Shutang Wang, Mingpu Cao, Xianliang | 1997 | 中国有色金属学会会刊:英文版1997，7，2： | 0 |
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