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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | Fatigue behavior of high-entropy alloys: A review显示文摘Fatigue failures cost approximately 4% of the United States' gross domestic product(GDP). The design of highly fatigue-resistant materials is always in demand. Different from conventional strategies of alloy design, high-entropy alloys(HEAs) are defined as materials with five or more principal elements, which could be solid solutions. This locally-disordered structure is expected to lead to unique fatigue-resistant properties. In this review, the studies of the fatigue behavior of HEAs during the last five years are summarized. The four-point-bending high-cycle fatigue coupled with statistical modelling, and the fatigue-crack-growth behavior of HEAs, are reviewed. The effects of sample defects and nanotwins-deformation mechanisms on four-point-bending high-cycle fatigue of HEAs are discussed in detail. The influence of stress ratio and temperature on fatigue-crack-growth characteristics of HEAs is also discussed. HEAs could exhibit comparable or greater fatigue properties, relative to conventional materials. Finally,the possible future work regarding the fatigue behavior of HEAs is suggested. | CHEN PeiYong LEE Chanho WANG Shao-Yu SEIFI Mohsen LEWANDOWSKI John J DAHMEN Karin A JIA HaoLing XIE Xie CHEN BiLin YEH Jien-Wei TSAI Che-Wei YUAN Tao LIAW Peter K | 2018 | Science China(Technological Sciences)2018，61，2： | 3 |
| 4 | Creation of an additional glycwsylation site as a mechanism for type I antithrombin deficiency显示文摘 | FITCHES AC LEWANDOWSKI K OLDS RJ | 2001 | Thromb Haemost2001，86，4： | 1 |
| 5 | Synthesis and properties of waterborne self - crosslinkable sulfo - urethane silanol dispersions 显示文摘 | LEWANDOWSKI K KREPSKI L R MICKUS D E et al | 2002 | J Polym Sci Part A Polym Chem2002，40，17： | 1 |
| 6 | Orexins/Hypocretins modulate the activity of NPY-positive and negative neurons in the rat intergeniculate leaflet via OX1 and OX2 receptors显示文摘 | Palus K Chrobok L Lewandowski M H | 2015 | Neuroscience2015，300，15： | 1 |
| 7 | Increased circulating levels of matrix metaUoproteinase-2 and -9 in women with the polycystic ovary syndrome显示文摘 | Lewandowski K C Komorowski J O'Callaghan C J | 2006 | J Clin Endocrinol Metab2006，91，3： | 1 |
| 8 | Effects of insulin and glucocoricoids on the leptin system are mediated through free leptin显示文摘 | Randeva HS O'Callaghan CJ | 2001 | Clinical Endocrinology2001，54，： | 1 |
| 9 | Primary breast lym-phoma-a review of the literature and report of three cases显示文摘 | Joks M Mysliwiec K Lewandowski K | 2011 | Arch Med Sci2011，7，1： | 1 |
| 10 | Epidemiology of ARDS显示文摘 | Lewandowski K Lewandowski M | 2006 | Minerva Anestesiol2006，72，6： | 1 |
| 11 | High survival rate in 122 ARDS patients managed according to a clinical algorithm including extracorporeal membrane oxygenation显示文摘 | Lewandowski K Rossaint R Pappert D | | 0，，： | 1 |
| 12 | Primary breast lymphoma -a re- view of the literature and report of three cases 显示文摘 | Joks M Mysliwiec K Lewandowski K | 2011 | Arch Med Sci2011，7，1： | 1 |
| 13 | The prevalence of C807T mutation of glycoprotein Ia gene among young male survivors of myocardial infarction: a relation with coronary angiography results显示文摘 | Lewandowski K Swierczynska A Kwasnikowshi P | 2005 | Kardiol Pol2005，63，2： | 1 |
| 14 | Adsorption of polyelectrolytes onto oxides-the influence of ionic strength,molar mass,and Ca^2+ ions显示文摘 | HLEN K V LEWANDOWSKI H NARRES H | 2000 | Colloids and Surfaces2000，，： | 1 |
| 15 | Pri-mary breast lymphoma-a review of the literature andreport of three cases显示文摘 | JOKS M MYSLIWIEC K LEWANDOWSKI K | 2011 | Arch Med Sci2011，7，： | 1 |
| 16 | A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells显示文摘 | WILLIAMS C EDVARDSSON K LEWANDOWSKI S A | 2008 | Oncogene2008，27，7： | 1 |
| 17 | Gene expression during abscission of Valencia citrus fruit and leaves显示文摘 | BURNS J K NAIRN C J LEWANDOWSKI D J | 1995 | Proc Fla State Hort Soc1995，108，1： | 1 |
| 18 | Interference-based forgetting in verbal short-termmemory 显示文摘 | Lewandowsky S Geiger S M Oberauer K | 2008 | Journal of Memory and Language2008，59，2： | 1 |
| 19 | Notemporal decay in verbal short-term memory 显示文摘 | Lewandowsky S Oberauer K Brown G D A | 2009 | Trends in Cognitive Sciences2009，13，3： | 1 |
| 20 | Dry -peelable temporary protective coatings from waterborne serf - erossfinkable sulfourethane - silanol dispersions 显示文摘 | LEWANDOWSKI K KREPSKI L R MICKUS D E | 2004 | J Appl Polym Sei2004，91，3： | 1 |
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