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| 1 | Clevidipine effec- tively and rapidly controls blood pressure preoperatively incardiac surgery patients : the results of the randomized, placebo- controlled efficacy study of clevidipine assessing its preoperative hypertensive effect in cardiac surgery-l显示文摘 | LEVY JH MANCAO MY GITTER R | 2007 | Anesth Analg2007，105，4： | 1 |
| 2 | Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients: the results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-1 显示文摘 | Levy JH Mancao MY Gitter R | 2007 | Anesthesia and Analgesia2007，105，4： | 1 |
| 3 | Characterization of plasmid DNA transfer into mouse skeletal muscle: evaluation of uptake mechanism, expression and secretion of gene products into blood 显示文摘 | Barron LG Szoka FC | 1996 | Gene Ther1996，3，： | 1 |
| 4 | Polylactic acid mesh recon- struction of the anterior iliac crest after bone harvesting reduces ear- ly postoperative pain after anterior cervical fusion surgery显示文摘 | Wang MY Levi AD Shah S | 2002 | Neu- rosurgery2002，51，2： | 1 |
| 5 | The incidence of and risk factors for venous thromboembolism (VTE) and bleeding among 1514 patients undergoing hematopoietic stem cell transplantation: implications for VTE prevention 显示文摘 | Gerber DE Segal JB Levy MY | 2008 | Blood2008，112，3： | 1 |
| 6 | Characterization of diazepam su-bmicron emulsion in terrace:role of oleoc acid显示文摘 | Levy MY Schutze W Fuhreret C | 1994 | Microencapsulation1994，11，1： | 1 |
| 7 | Drug release from submicronized o/w emulsion:a new in vitro kinetic evaluation model显示文摘 | Levy MY Benit S | 1990 | Int J Pharm1990，66，13： | 1 |
| 8 | Characterization of diazepam submicron emulsion interface: role of oleic acid 显示文摘 | Levy MY Schutze W Fuhrer C | 1994 | J Microencapsulation1994，11，1： | 1 |
| 9 | Submicron emulsions as colloidal drug carriers for intravenous administration:comprehensive physicochemical characterization显示文摘 | Benita S Levy MY | | 0，，： | 1 |
| 10 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 11 | Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients:the results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-l显示文摘 | Levy JH Mancao MY Gitter R | 2007 | Anesth Analg2007，105，： | 1 |
| 12 | Cyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation显示文摘 | Levy MY Sidana A Chowdhury WH | 2009 | J Pharmacol Exp Ther2009，330，2： | 1 |
| 13 | Characterization of diazepam submicron emulsion interface: role of oleic acid 显示文摘 | Levy MY Schutze W Fuhrer C | 1994 | J Microeneapsul1994，11，1： | 1 |
| 14 | Polylactie acid mesh Re-construction of the anterior iliac crest after bone harvesting reduces early postoperative pain after anterior cervical fu- sion surgery 显示文摘 | Wang MY Levi AD Shah S | 2002 | Neurosurgery2002，51，2： | 1 |
| 15 | Characterization of plasmid DNA transfer into mouse skeletal muscle: evaluation of uptake mechanism, expression and secretion of gene products into blood显示文摘 | Levy MY Barron LG Meyer KB | 1996 | Gene Ther1996，3，3： | 1 |
| 16 | Discussion 55-6 Intradural spinal arachnoid cysts in adults显示文摘 | Wang MY Levi AD Green BA | 2003 | Surg Neurol2003，60，1： | 1 |
| 17 | Drug release from submicronized O/ W emulsion: a new in vitro kinetic evaluation model显示文摘 | Levy MY Benita S | 1990 | IntJPharm1990，66，13： | 1 |
| 18 | Acute myeloid leukemia: focus on noveltherapeutic strategies 显示文摘 | LinTL Levy MY | 2012 | Clin Med Insights Oncol2012，6，： | 1 |
| 19 | Clevidipine effectively andrapidly controls blood pressure preoperatively in cardiac surgery pa-tients: The results of the randomized, placebo-controlled efficacystudy of clevidipine assessing its preoperative antihypertensive effectin cardiac surgery-1显示文摘 | Levy JH Mancao MY Gitter R | 2007 | Anesth Analg2007，105，： | 1 |
| 20 | Subnanomulsion as colloidal drug carriers for intravenous administration: comprehensive physicochemical characterization显示文摘 | Benita S Levy MY | 1993 | J Pharm Sci1993，82，11： | 1 |
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