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| 1 | An update on biomarkers of potential benefit with bevacizumab for breast cancer treatment: Do we make progress?显示文摘As the first monoclonal antibody against vascular endothelial growth factor(VEGF), bevacizumab(BEV) is a definitely controversial antiangiogenic therapy in breast cancer. The initial excitement over improvements in progression-free survival(PFS) with BEV was tempered by an absence of overall survival(OS) benefit and serious adverse effects. Missing targeted population urged us to identify the predictive biomarkers for BEV efficacy. In this review we focus on the research in breast cancer and provide recent investigations on clinical, radiological,molecular and gene profiling markers of BEV efficacy, including the new results from randomized phase III clinical trials evaluating the efficacy of BEV in combination with comprehensive biomarker analyses. Current evidences indicate some predictive values for genetic variants, molecular imaging, VEGF pathway factors or associated factors in peripheral blood and gene profiling. The current challenge is to validate those potential biomarkers and implement them into clinical practice. | Xu Liang Huiping Li Florence Coussy Celine Callens Florence Lerebours | 2019 | Chinese Journal of Cancer Research2019，31，4： | 2 |
| 2 | A Randomized, Double-Blind, Controlled Withdrawal Trial in Crohn’s Disease Patients in Long-term Remission on Azathioprine显示文摘 | Marc Lémann Jean-Yves Mary Jean-Frédéric Colombel Bernard Duclos Jean-Claude Soule Eric Lerebours Robert Modigliani Yoram Bouhnik | 2005 | Gastroenterology2005，，7： | 2 |
| 3 | Natural History of Pediatric Crohn’s Disease: A Population-Based Cohort Study显示文摘 | Gwenola Vernier–Massouille Mamadou Balde Julia Salleron Dominique Turck Jean Louis Dupas Olivier Mouterde Véronique Merle Jean Louis Salomez Julien Branche Raymond Marti éric Lerebours Antoine Cortot Corinne Gower–Rousseau Jean Frédéric Colombel | 2008 | Gastroenterology2008，，4： | 2 |
| 4 | Effeet of Perindopril on the onset and progression of left ventricular dysfunction in Duchenne muscular dystrophy显示文摘 | Duboc D Meune C Lerebours G | 2005 | J Am Coll Cardiol2005，45，： | 1 |
| 5 | Innovation in coronary artery dis- ease and heart failure : clinical benefits of pure heart rate reduction with ivabradine显示文摘 | Canet E Lerebours G Vilaine JP | 2011 | Ann N Y Acad Sci2011，1222，： | 1 |
| 6 | Excess primary intestinal lymphoproliferative disorders in patients with inflammatory bowel disease显示文摘 | Harry Sokol Laurent Beaugerie Marc Maynadié David Laharie Jean‐Louis Dupas Bernard Flourié Eric Lerebours Laurent Peyrin‐Biroulet Matthieu Allez Tabassome Simon Fabrice Carrat Nicole Brousse | 2012 | Inflamm Bowel Dis2012，，11： | 1 |
| 7 | Utilisation de ClinOléic en pathologie digestive显示文摘 | Lerebours E Lescut D Guedon C | 1996 | Nutr Clin Métabol1996，10，： | 1 |
| 8 | lSFDG PET/CT ima- ging versus dynamic contrast-enhanced CT for staging and prog- nosis of inflammatory breast cancer显示文摘 | Champion L Lerebours F Cherel P | 2013 | Eur J Nucl Med Mol Im- aging2013，40，8： | 1 |
| 9 | Change in energy and protein status during chemotherapy in patients with acute leukemia显示文摘 | Tilly H Rimbert A | 1988 | Cancer1988，61，12： | 1 |
| 10 | NF-kappa B genes have a major role in inflammatory breast cancer显示文摘 | Lerebours F Vacher S Andrieu C | 2008 | BMC Cancer2008，8，41： | 1 |
| 11 | Inflammatory bowel disease in spouses and their offspring显示文摘 | David Laharie Stéphane Debeugny Marc Peeters André Van Gossum Corinne Gower-Rousseau Jacques Bélahe René Fiasse Jean-Louis Dupas Eric Lerebours Sandrine Piotte Antoine Cortot Séverine Vermeire Bruno Grandbastien Jean-Frédéric Colombel | 2001 | Gastroenterology2001，，： | 1 |
| 12 | NF-kappa B genes have a major role in inflammatory breast cancer显示文摘 | Lerebours F Vacher S Andrieu C | 2008 | BMC Cancer2008，8，： | 1 |
| 13 | Deletion mapping of the ttunor suppressor locus involved in colorectal cancer on chromo- some band 8p21 显示文摘 | Lerebours F Olschwang S Thuille B | 1999 | Genes Chromosomes Cancer1999，25，： | 1 |
| 14 | Endoscopic markers of villous atrophy are not useful for the detection of celiac disease in patients with dyspeptic symptoms显示文摘 | S. Lecleire F. Di Fiore M. Antonietti G. Savoye F. Lemoine F. Le Pessot E. Lerebours P. Ducrotté | 2006 | Endoscopy2006，，07： | 1 |
| 15 | Intravenous cyclosporine in attacks of ulcerative colitis显示文摘 | Dr. Franck Carbonnel MD Arnaud Boruchowicz MD Bernard Duclos MD Jean Claude Soulé MD Eric Lerebours MD Marc Lémann MD Jean Bela?che MD Jean Frédéric Colombel MD Jacques Cosnes MD Jean Pierre Gendre MD | 1996 | Digestive Diseases and Sciences1996，，12： | 1 |
| 16 | Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature显示文摘 | Bieche I Lerebours F Tozlu S | 2004 | Clin Cancer Res2004，10，20： | 1 |
| 17 | Comparative analysis of gene expression in brain, liver, skeletal muscles, and gills of zebrafish ( Danio rerio ) exposed to environmentally relevant waterborne uranium concentrations 显示文摘 | LEREBOURS A GONZALEZ P ADAM C | 2009 | Environ Toxicol Chem2009，28，6： | 1 |
| 18 | Antianginal and Antiischemic Effects of Ivabradine, an If Inhibitor, in Stable Angina: A Randomized, Double-Blind, Multicentered, Placebo-Controlled Trial显示文摘 | Jeffrey S. Borer Kim Fox Patrice Jaillon Guy Lerebours | 2003 | Circulation: Journal of the American Heart Association2003，，6： | 1 |
| 19 | Effect of perindopril on the onset and progression of left ventricular dysfunction in Duchenne muscular dystrophy显示文摘 | Denis Duboc Christophe Meune Guy Lerebours Jean-Yves Devaux Guy Vaksmann Henri-Marc Bécane | 2005 | Journal of the American College of Cardiology2005，，6： | 1 |
| 20 | Argon plasma coagulation in the treatment of hemorrhagic radiation proctitis is efficient but requires a perfect colonic cleansing to be safe显示文摘 | E Ben-Soussan M Antonietti G Savoye S Herve P Ducrotté E Lerebours | 2004 | European Journal of Gastroenterology & Hepatology2004，，12： | 1 |
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