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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Impact of polyacrylamide delivery method with lime or gypsum for soil and nutrient stabilization 显示文摘 | Lepore B J Thompson A M Petersen A | 2009 | Soil and Water Conservation2009，64，3： | 1 |
| 3 | Long-term fate of neural precursors cells following transplantation into develo- ping and adult CNS显示文摘 | Lepore AC Nehuber B Connors TM | 2006 | Neuroscienee2006，142，1： | 1 |
| 4 | Long-tem fate of Neural precursors cells following transplantation into developing and adult CNS显示文摘 | Lepore AC Neuhuber B Connors TM | | 0，，6： | 1 |
| 5 | ct-Blockers for benign pro- static hyperplasia:the new era显示文摘 | Lepor H Kazzazi A Djavan B | 2012 | Curr Opin Urol2012，22，1： | 1 |
| 6 | Relationship between prostatic epithelial volume and serum prostate specific antigen levels显示文摘 | LEPOR H WANG B SHAPIRO E | 1994 | Urology1994，44，2： | 1 |
| 7 | Three-dimensional structure of the quorum-quenching N-acylhomoserine lactone hydrolase from Bacillus thuringiensis显示文摘 | Liu D Lepore B W Petsko G A | 2005 | Proc Natl Acad Sci USA2005，102，11： | 1 |
| 8 | alpha-Blockers for be- nign prostatic hyperplasia~ the new era显示文摘 | LEPOR H KAZZAZI A DJAVAN B | 2012 | Curt Opin Urol2012，22，1： | 1 |
| 9 | Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis显示文摘 | LIU D LEPORE B W PETSKO G A | 2005 | Proceedings of the National Academy of Sciences of the United States of America2005，102，11： | 1 |
| 10 | Long-term fate of neural precursor cells following transplantation into developing and adult CNS显示文摘 | Lepore AC Neuhuber B Connors TM | 2006 | Neuroscience2006，142，： | 1 |
| 11 | Long-term fate of neural precursor cells following transplantation into developing and adult CNS显示文摘 | Lepore AC Neuhuber B Connors TM | 2006 | Neuroscience2006，142，1： | 1 |
| 12 | α-Blockers for benign prostatic hyperplasia: thenew era显示文摘 | Lepor H Kazzazi A Djavan B | 2012 | Current opinion in urology2012，22，1： | 1 |
| 13 | Long-term fate of neural preeumor cells following transplantation into developing and adult CNS显示文摘 | Lepore AC Neuhuber B Connors TM | 2006 | Neumscience2006，139，2： | 1 |
| 14 | Relationship between prostatic epithelial volume and serum prostate-specific antigen levels 显示文摘 | Lepor H Wang B Shapiro E | 2006 | J Urology2006，44，4： | 1 |
| 15 | Impact of polyacrylamide delivery method with lime or gypsum for soil and nutrient stabilization 显示文摘 | Lepore B J Thompson A M Petersen A | 2009 | Soil and Water Conservation2009，64，3： | 1 |
| 16 | Long-term fate of neural precursors cells following transplantation into developing and adult CNS显示文摘 | Lepore AC Neuhuber B Connors T M | 2006 | Neuroscience2006，142，： | 1 |
| 17 | Long-term fate of neural precursor cells following transplantation into developing and adult CNS显示文摘 | Lepore AC Neuhuber B Connors TM Han SS Liu Y Daniels MP | 2006 | Neuroscience2006，142，1： | 1 |
| 18 | Identification of rotary machines excitation forces using wavelet transform and neural networks显示文摘 | Lepore F P Santos M B Barreto R G | 2002 | Shock and Vibration2002，9，5： | 1 |
| 19 | Long-term fate of neural precursor cells following transplantation into developing and adult CNS 显示文摘 | LEPORE AC NEUHUBER B CONNORS TM | 2006 | Neuroscience2006，139，2： | 1 |
| 20 | Comparison of the cellular composition of benign prostatic hyperplasia in Chinese and Caucasian-American men显示文摘 | Lepor H Shapiro E Wang B | 1996 | Urology1996，47，1： | 1 |
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