|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 2 | Helicobacter pylori Induces Increased Expression of Toll‐Like Receptors and Decreased Toll‐Interacting Protein in Gastric Mucosa that Persists Throughout Gastric Carcinogenesis显示文摘 | Pedro Pimentel‐Nunes Nádia Gon?alves Inês Boal‐Carvalho Luís Afonso Paula Lopes Roberto Roncon‐Albuquerque Rui Henrique Luís Moreira‐Dias Adelino F. Leite‐Moreira Mário Dinis‐Ribeiro | 2012 | Helicobacter2012，，1： | 2 |
| 3 | Transmission capacity: availability, maximum, transfer and reliability显示文摘 | Leite da S A M de Carvalho C J G da Fonseca M L A | 2002 | IEEE Transactions on Power Systems2002，17，3： | 1 |
| 4 | Laminated three-dimensional biodegradable foams for use in tissue engineering显示文摘 | Mikos A G Sarakinos G Leite S M | 1993 | Biomaterials1993，14，： | 1 |
| 5 | Brown pigment of the nanopowder spinel ferrite prepared by combustion reaction显示文摘 | COSTA A C F M LEITE A M D FERREIRA H S | | 0，，： | 1 |
| 6 | External validation of a classification for methylene blue magnification chromoendoscopy in premalignant gastric lesions显示文摘 | Miguel Areia Pedro Amaro Mário Dinis-Ribeiro Maria Augusta Cipriano Carol Marinho Altamiro Costa-Pereira Carlos Lopes Luís Moreira-Dias José Manuel Rom?ozinho Hermano Gouveia Diniz Freitas Maximino Correia Leit?o | 2008 | Gastrointestinal Endoscopy2008，，7： | 1 |
| 7 | Sensitivity-enhanced reflection Z-scan by oblique incidence of a polarized beam显示文摘 | Martinelli M Bian S Leite J R | | 0，，： | 1 |
| 8 | Light spectrum management using colored nets to control the growth and blooming of Phalaenopsis显示文摘 | Leite C A Ito R M Lee G T S | 2008 | Acta Hort2008，770，： | 1 |
| 9 | Biosorption of copper by Paenibacillus polymyxa cells and their exopolysaccharide 显示文摘 | ACOSTA M P VALAMAN E LEITE S G F | 2005 | World Jouranal of Microbiology & Biotechnology2005，21，： | 1 |
| 10 | Composite reliability assessment based on Monte Carlo simulation and artificial neural networks 显示文摘 | Leite S A M Chaves R L Fonseca M L A | 2007 | IEEE Transactions on Power Systems2007，22，3： | 1 |
| 11 | 显示文摘 | Zanetti S M Leite E R Longo E | 1999 | J Europ Ceram Soc1999，19，： | 1 |
| 12 | Chemical at-tributes and carbon stocks in an Oxisol under no - tillage in sa-vannah of Piaui state 显示文摘 | Leite L F C Galvao S R S Neto M R H | 2010 | Revista Brasileira de EngenhariaAgricola e Ambiental2010，14，12： | 1 |
| 13 | Population structure and reproductive dynamics of Octopus insularis (Cephalopoda: Octopodidae) in a coastal reef environment along northeastern Brazil 显示文摘 | LIMA F D LEITE T S HAIMOVICI M | 2014 | Fisheries Research2014，，152： | 1 |
| 14 | Laminated three-dimensional biodegradable foams for use in tissue engineering 显示文摘 | Mikos A G Sarakinos G Leite S M | 1993 | Biomaterials1993，14，： | 1 |
| 15 | Laminated three-dimensional biodegradable foams for use in tissue engineering显示文摘 | Mikos A G Sarakinos G Leite S M | 1993 | Biomaterials1993，14，5： | 1 |
| 16 | Chronic Trypanosoma cruzi infection associated with low incidence of 1, 2 - dimethylhydrazine-induced colon cancer in rats显示文摘 | OLIVEIRA E C LEITE M S MIRANDA J A | 2001 | Carcinogenesis2001，22，5： | 1 |
| 17 | Change in expression of miR-let7c,miR-100,and miR-218 from high grade localized prostate cancer to metastasis显示文摘 | Leite K R Sonsa-Canavez J M Reis S T | 2009 | Urol Oncol2009，，： | 1 |
| 18 | Nonfunctional requirements: from elicitation to conceptual models 显示文摘 | Cysneiros L M do Prado Leite J C S | 2004 | IEEE Transactions on Software Engineering2004，30，5： | 1 |
| 19 | Type 2 heat-labile enterotoxin (LT-II)-producing Escherichia coli isolated from ostriches with diarrhea显示文摘 | Ana Rita M. Nardi Márcia R. Salvadori Lia T. Coswig Maria Sílvia V. Gatti Domingos S. Leite Geórgio F. Valadares Manoel Garcia Neto Rubén P. Shocken-Iturrino Jesús E. Blanco Tomomasa Yano | 2004 | Veterinary Microbiology2004，，3： | 1 |
| 20 | Evolution of Thermodynamic Potentials in Closed and Open Nanocrystalline Systems:Ge-Si:Si(001)Islands显示文摘 | Leite M S Malachias A Kycia S W | 2008 | Phys Rev Lett2008，100，22： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员