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| 1 | Mechanism of intrauterine infection of hepatitis B virus显示文摘AIM:To explore the possible mechanism of intrauterine infection of hepatitis B virus (HBV).METHODS: HBV DNA was detected in vaginal secretion and amniotic fluid from 59 HBsAg-positive mothers and in venous blood of their newborns by PCR. HBsAg and HBcAg in placenta were determined by ABC immunohistochemistry.RESULTS:The rate of HBV intrauterine infection was 40.1% (24/59). HBV DNA was detected in 47.5% of amniotic fluid samples and 52.5% of vaginal secretion samples respectively.HBsAg and HBcAg were detected in placentas from HBsAg-positive mothers. The concentration of the two antigens decreased from the mother's side to the fetus's side, in the following order:maternal decidual cells>trophoblastic cells> villous mesenchymal cells>villous capillary endothelial cells. However, in 4 placentas the distribution was in the reverse order. HBsAg and HBcAg were detected in amniotic epithelial cells from 32 mothers.CONCLUSION:The main route of HBV transmission from mother to fetus is transplacental, from the mother side of placenta to the fetus side. However, HBV intrauterine infection may take place through other routes. | Shu-LinZhang Ya-FeiYue Gui-QinBai LeiShi HuiJiang | 2004 | World Journal of Gastroenterology2004，10，3： | 48 |
| 2 | 移植肾组织C4d阳性急性排斥21例临床观察显示文摘目的:观察中国肾移植受者移植肾组织肾小管周围毛细血管(PTC)C4d阳性的急性排斥反应(AR)患者的临床过程及其转归,为此类患者的救治提供借鉴.方法:1999年4月~2004年6月间发生AR的肾移植受者,利用间接免疫荧光法检测移植肾组织C4d的沉积,对阳性者观察临床、病理特点、治疗反应以及临床转归.结果:21例C4d阳性AR患者,主要发生在年轻男性(33.5±7.2岁)与中年女性(40.9±6.7岁)中;7例术前群体反应性抗体(PRA)高,66.7%的AR发生在术后2周内(14/21),6个月后仍然有3例发生,其中2例与免疫抑制剂的撤换有关;62%的患者需透析治疗,仅4例对冲击治疗有反应,4例接受免疫吸附联合FK506+霉酚酸酯(MMF)治疗者有3例完全逆转,1例移植肾丢失,1例受者主要因消化道反应未能成功切换FK506而单独应用IA,最终未能逆转;12例单纯应用FK506+MMF治疗者(1例加用抗胸腺球蛋白)有6例完全逆转,4例部分缓解.所有需要透析的患者均接受连续性血液净化(CBP)治疗,1例单独应用长时间CBP治疗的受者也成功逆转.患者性别和发生AR的时间与移植肾转归有关,后期发生的AR以及女性受者预后较差.结论:C4d阳性的AR多发生在术后早期;传统上的AR高危人群发生率高,晚期也可发生,但预后较差;组织学上多伴PTC部位中性粒细胞浸润和(或)小球炎,对激素的疗效差.FK506联合MMF能够有效的逆转或控制大部分中国人C4d阳性AR,CBP在治疗中可能起了一定的作用. | 孙启全 刘志红 陈劲松 陈惠萍 季大玺 尹广 季曙明 周虹 唐政 黎磊石 LI Leishi | 2005 | 肾脏病与透析肾移植杂志2005，14，1： | 11 |
| 3 | Robust fault detection for a class of nonlinear time-delay systems 显示文摘 | BAI Leishi TIAN Zuohua SHI Songjiao | 2007 | Journal of the Franklin Institute2007，344，6： | 1 |
| 4 | End-stage renal disease in China显示文摘 | li leishi | 1996 | Kidney Int1996，49，： | 1 |
| 5 | Renal transplantation in China: ten years of experience at Nanjing Jinling Hospital 显示文摘 | Leishi L Qiquan S | 2006 | Clin Transpl2006，，： | 1 |
| 6 | Glucose transporters:implication for diabetic nephropathy显示文摘 | Liu Zhihong Li Leishi | | 0，，06： | 1 |
| 7 | End-sta renal disease in China显示文摘 | Li leishi | 1996 | Kidney Lut1996，49，： | 1 |
| 8 | Renal Transplantation in China:Ten years of experience at Nanjing Jinling Hospital显示文摘 | Leishi L Qiquan S | 2006 | Clin Transpl2006，，： | 1 |
| 9 | End-stage renal disease in China显示文摘 | Li leishi | 1996 | Kidney lnt1996，49，3： | 1 |
| 10 | Exciton in a strained (001)‐oriented zinc‐blende GaN/Al<sub>x</sub>Ga<sub>1‐x</sub>N ellipsoidal finite‐potential quantum dot under hydrostatic pressure显示文摘 | LeiShi Zu WeiYan | 2011 | Phys Status Solidi (c)2011，，1： | 1 |
| 11 | End-stage renal disease in China显示文摘 | Leishi Li | 1996 | kidney Int1996，49，： | 1 |
| 12 | Epidemiologie data of renal diseases from a single unit in China:analysis based on 13,519 renal biopsies显示文摘 | Li Leishi Liu Zhihong | 2004 | Kidney Int2004，66，： | 1 |
| 13 | Synthesis of Two Novel Rhenium(I) Bipyridyl Photosensitive Dyes显示文摘Two novel rhenium(I) 2, 2′-bipyridyl complexes, [(4,4′-di-COOEt-bipy) Re(CO)3 (NCCH3)PF6] and [(4,4′-di-COOEt-bipy) Re (CO)3 (NCS)], a model complex [(4,4′-di-COOEt-bipy) Re (CO)3 (pyridine)PF6], were synthesized. Their ground state electronic spectra and emission spectra were measured in acetonitrile. The MLCT absorption maximum of the complex exhibited a considerable red shift as the ligand changed from pyridine to CNCH3, or SCN. | ShiGuoSUN XiaoJunPENG MingWenFAN YongQianXU LeiSHI LiChengSU | 2004 | Chinese Chemical Letters2004，15，8： | 1 |
| 14 | End-stage renal disease in China显示文摘 | Li Leishi | 1996 | Kidney Int1996，49，： | 1 |
| 15 | End stage renal disease in China显示文摘 | Li Leishi | 1996 | Kidney Int1996，49，： | 1 |
| 16 | ClustNails:Visual Analysis of Subspace Clusters显示文摘Subspace clustering addresses an important problem in clustering multi-dimensional data.In sparse multi-dimensional data,many dimensions are irrelevant and obscure the cluster boundaries.Subspace clustering helps by mining the clusters present in only locally relevant subsets of dimensions.However,understanding the result of subspace clustering by analysts is not trivial.In addition to the grouping information,relevant sets of dimensions and overlaps between groups,both in terms of dimensions and records,need to be analyzed.We introduce a visual subspace cluster analysis system called ClustNails.It integrates several novel visualization techniques with various user interaction facilities to support navigating and interpreting the result of subspace clustering.We demonstrate the effectiveness of the proposed system by applying it to the analysis of real world data and comparing it with existing visual subspace cluster analysis systems. | Andrada Tatu Leishi Zhang Enrico Bertini Tobias Schreck Daniel Keim Sebastian Bremm Tatiana von Landesbergert | 2012 | Tsinghua Science and Technology2012，17，4： | 1 |
| 17 | RFDF design for linear time-delay systems with unknown inputs and parameter uncertainties显示文摘 | Bai Leishi Tian Zuohua Shi Songjiao | 2007 | International Journal of Systems Science2007，38，2： | 1 |
| 18 | End-stage renal disease in china显示文摘 | LI Leishi | 1996 | Kidney Int1996，49，： | 1 |
| 19 | The expression of stem cell‐related indicators as a prognostic factor in human lung adenocarcinoma显示文摘 | Xue‐YanZhang Qiang‐GangDong Jin‐SuHuang Ai‐MiHuang Chun‐LeiShi BoJin Hui‐FangSha Jiu‐XianFeng QinGeng JinZhou Hui‐LiXu Bao‐huiHan | 2010 | J Surg Oncol2010，，7： | 1 |
| 20 | End- stage renal disease in China显示文摘 | Li Leishi | 1996 | Kidney Int1996，49，： | 1 |
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