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| 1 | Contemporary review of drug-induced pancreatitis: A different perspective显示文摘Although gallstone and alcohol use have been consid-ered the most common causes of acute pancreatitis, hundreds of frequently prescribed medications are as-sociated with this disease state. The true incidence is unknown since there are few population based studies available. The knowledge of drug induced acute pan-creatitis is limited by the availability and the quality of the evidence as the majority of data is extrapolated from case reports. Establishing a definitive causal rela-tionship between a drug and acute pancreatitis poses a challenge to clinicians. Several causative agent classifi-cation systems are often used to identify the suspected agents. They require regular updates since new drug induced acute pancreatitis cases are reported continu-ously. In addition, infrequently prescribed medications and herbal medications are often omitted. Furthermore, identification of drug induced acute pancreatitis with new medications often requires accumulation of post market case reports. The unrealistic expectation for a comprehensive list of medications and the multifacto-rial nature of acute pancreatitis call for a different ap-proach. In this article, we review the potential mecha-nisms of drug induced acute pancreatitis and providethe perspective of deductive reasoning in order to allow clinicians to identify potential drug induced acute pan-creatitis with limited data. | Whitney Y Hung Odaliz Abreu Lanfranco | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，4： | 10 |
| 2 | Robotic Surgery: A Current Perspective显示文摘 | Anthony R. Lanfranco Andres E. Castellanos Jaydev P. Desai William C. Meyers | 2004 | Annals of Surgery2004，，1： | 4 |
| 3 | Habitual salt intake and risk of gastric cancer: A meta-analysis of prospective studies显示文摘 | Lanfranco D’Elia Giovanni Rossi Renato Ippolito Francesco P. Cappuccio Pasquale Strazzullo | 2012 | Clinical Nutrition2012，，4： | 3 |
| 4 | Lactic acid fermentation of Brassica rapa:chemical and microbial evaluation of a typical Italian product(Brovada) 显示文摘 | MICHELA M MAPdLENA M LANFRANCO C | 2004 | Eur Food Res Technol2004，218，1： | 1 |
| 5 | Polycyclic aromatic hydrocarbons in edible fats and oils: occurrence and analytical methods显示文摘 | Sabrina Moret Lanfranco S Conte | 2000 | Journal of Chromatography A2000，，1： | 1 |
| 6 | Lactic acid fermentation of Brassica rapa: chemical and microbial evaluation of a typical Italian product (Brovada)显示文摘 | MICHELA M MARILENAM LANFRANCO C | 2004 | Eur Food Res Technol2004，，218： | 1 |
| 7 | Klinefeher' s syndrome 显示文摘 | Lanfranco F Kamischke A Zitzmann M | 2004 | Lancet2004，364，9430： | 1 |
| 8 | Obstructive sleep apnoea syndrome impairs insulin sensitivity independently of anthropometric variables显示文摘 | Tassone F Lanfranco F Gianotti L | 2003 | Clin Endocrinol(Oxf)2003，59，3： | 1 |
| 9 | Simultaneous determination of volatile and semi-volatile aromatic hydrocarbons in virgin olive oil by headspace solid-phase microextraction coupled to gas chromatography/mass spectrometry显示文摘 | Stefania Vichi Lorena Pizzale Lanfranco S | 2005 | Journal of Chromatography A2005，1090，： | 1 |
| 10 | Klinefelter's syndrome显示文摘 | Lanfranco F Kamischke A Zitzmann M | 2004 | Lancet2004，364，9430： | 1 |
| 11 | Service activities'urban hierarchy and cumulative growth显示文摘 | Lanfranco Senn | 1993 | The Service Industries Journal1993，，2： | 1 |
| 12 | Generation of RAPD-PCR primers for the identification of isolates of Glomus mosseae, an arbuscular mycorrhizal fungus显示文摘 | LANFRANCO L WYSS P MARZACH C | 1995 | Molecular Ecology1995，4，： | 1 |
| 13 | DNA Probes for identification of the ectomycorrhizal fungus Tuber magnatum Pico 显示文摘 | Lanfranco L Myss P Marzachi G | 1993 | FEMS Microbiol Lett1993，，114： | 1 |
| 14 | Klinefelter' s Syndrome显示文摘 | Lanfranco F Kamschke A Zitzmann M | 2004 | Lancet2004，364，9430： | 1 |
| 15 | Klinefelter's syndrome 显示文摘 | Lanfranco F Kamischke A Zitzmann M | 2004 | Lancet2004，364，9430： | 1 |
| 16 | Concomitant impairment of growth hormone secretion and peripheral sensitivity in obese patients with obstructive sleep apnea syndrome显示文摘 | Gianotti L Pivetti S Lanfranco F | 2002 | J Clin Endocrinol Metab2002，87，： | 1 |
| 17 | Obstructive sleep apnoea syndrome impairs insulin sensitivity independently of anthropometric variables 显示文摘 | Tassone F Lanfranco F Gianotti L | 2003 | Clin Endocrinol (Oxf)2003，59，3： | 1 |
| 18 | Robotic surgery:a current perspective显示文摘 | Lanfranco AR Castellanos AE Desai JP | 2004 | Ann Surg2004，239，1： | 1 |
| 19 | Klinefelter' s syndrome 显示文摘 | Lanfranco F Kamishiche A Zitzmann M | 2004 | Lancet2004，367，7： | 1 |
| 20 | 炎症过程中载脂蛋白E亚型在星形胶质细胞和小胶质细胞的表达和分泌显示文摘神经炎症是神经退行性疾病的常见特征,受阿尔茨海默病危险因素载脂蛋白E(APOE)的调节。apoE蛋白在大脑中由星形胶质细胞和小胶质细胞合成。在人类APOE(E2、E3和E4)靶向替代小鼠的星形胶质细胞和小胶质细胞的原代培养物中,我们发现星形胶质细胞分泌2种apoE,而细胞内apoE只包含1种。2种形式的分泌型星形胶质细胞apoE在糖蛋白分离过程中均发生结合,酶促去除聚糖使2种形式的apoE融合为单一形式。因此,星形胶质细胞分泌的2种apoE是不同的糖基化的蛋白。小胶质细胞仅释放1种apoE,而细胞内apoE则由2种形式组成;分泌的apoE和2种细胞内apoE中的其中1种是糖基化的。我们用内源性肿瘤坏死因子α(TNFα)或外源性脂多糖(LPS)促炎刺激物处理原代培养的胶质细胞。LPS对星形细胞的apoE没有影响,而APOE2和APOE3小胶质细胞释放的apoE增加;对APOE4小胶质细胞也没有影响。与APOE2和APOE3小胶质细胞相比,APOE4小胶质细胞显示出更高的TNFα基线分泌。TNFα处理仅降低了APOE4星形胶质细胞中apoE的分泌和细胞表达。星形胶质细胞和小胶质细胞产生apoE种类的模式不受炎症的影响。2种处理后的星形胶质细胞中均未显示APOE mRNA的变化。总之,我们的数据表明,星形胶质细胞和小胶质细胞差异表达和分泌糖基化形式的apoE;并且相较于APOE2和APOE3,APOE4星形胶质细胞和小胶质细胞在免疫调节方面存在缺陷。 | Maria Fe Lanfranco Jordy Sepulveda Gregory Kopetsky GWilliam Rebeck 杜一星(编译) | 2021 | 神经损伤与功能重建2021，16，6： | 1 |
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