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| 1 | Mechanistic links between gut microbial community dynamics, microbial functions and metabolic health显示文摘Gut microbes comprise a high density, biologically active community that lies at the interface of an animal with its nutritional environment. Consequently their activity profoundly influences many aspects of the physiology and metabolism of the host animal. A range of microbial structural components and metabolites directly interact with host intestinal cells and tissues to influence nutrient uptake and epithelial health. Endocrine, neuronal and lymphoid cells in the gut also integrate signals from these microbial factors to influence systemic responses. Dysregulation of these host-microbe interactions is now recognised as a major risk factor in the development of metabolic dysfunction. This is a two-way process and understanding the factors that tip host-microbiome homeostasis over to dysbiosis requires greater appreciation of the host feedbacks that contribute to regulation of microbial community composition. To date, numerous studies have employed taxonomic profiling approaches to explore the links between microbial composition and host outcomes(especially obesity and its comorbidities), but inconsistent host-microbe associations have been reported. Available data indicates multiple factors have contributed to discrepancies between studies. These include the high level of functional redundancy in host-microbiome interactions combined with individual variation in microbiome composition; differences in study design, diet composition and host system between studies; and inherent limitations to the resolution of r RNA-based community profiling. Accounting for these factors allows for recognition of the common microbial and host factors driving community composition and development of dysbiosis on high fat diets. New therapeutic intervention options are now emerging. | Connie WY Ha Yan Y Lam Andrew J Holmes | 2014 | World Journal of Gastroenterology2014，20，44： | 4 |
| 2 | 论混合血清法筛检HIV抗体的可行性显示文摘本实验论证了用10份血清标本混合检测HIV抗体的可行性。应用美国Organon Teknika公司的ELISA法HIV-1抗体检测试剂进行试验,在只变动血清标本量与标本稀释液量比例,但两者总量不变的情况下进行测定。10份血清混合后血清量由5μl扩大到50μl,而标本稀释液量相应减少后标本的光密度(吸光值)略为增加,但均低于界限值,说明试验的特异性尚未受到影响。此外,将已经确证为HIV抗体阳性的血清标本1份同9份正常献血者血清混合后,经多次配对试验,均能正确反映出含有HIV抗体的标本,说明试验的敏感性不受影响,能保持原法的水平。由于混合血清法检测HIV抗体可节约开支10倍,同时节省人力、物力和工时等众多优点,故容易推广应用。 | 季阳 瞿德敏 Chyang T. Fang Ellen Lam Ba The Ha | 1992 | 中国输血杂志1992，5，1： | 2 |
| 3 | Isolated Low Levels of High-Density Lipoprotein Cholesterol Are Associated With an Increased Risk of Coronary Heart Disease: An Individual Participant Data Meta-Analysis of 23 Studies in the Asia-Pacific Region显示文摘 | Rachel R. Huxley Federica Barzi Tai Hing Lam Sebastien Czernichow Xianghua Fang Tim Welborn Jonathan Shaw Hirotsugu Ueshima Paul Zimmet Sun Ha Jee Jeetesh V. Patel Ian Caterson Vlado Perkovic Mark Woodward | 2011 | Circulation2011，，19： | 2 |
| 4 | Adherence to Screening for Hepatocellular Carcinoma Among Patients with Cirrhosis or Chronic Hepatitis B in a Community Setting显示文摘 | Carrie R. Wong Ruel T. Garcia Huy N. Trinh Khoa D. Lam Nghi B. Ha Huy A. Nguyen Khanh K. Nguyen Brian S. Levitt Mindie H. Nguyen | 2009 | Digestive Diseases and Sciences2009，，12： | 2 |
| 5 | Ecoregional variations of aboveground biomass and stand structure in evergreen broadleaved forests显示文摘Biotic and abiotic factors control aboveground biomass(AGB)and the structure of forest ecosystems.This study analyses the variation of AGB and stand structure of evergreen broadleaved forests among six ecoregions of Vietnam.A data set of 1731-ha plots from 52 locations in undisturbed old-growth forests was developed.The results indicate that basal area and AGB are closely correlated with annual precipitation,but not with annual temperature,evaporation or hours of sunshine.Basal area and AGB are positively correlated with trees>30 cm DBH.Most areas surveyed(52.6%)in these old-growth forests had AGB of 100–200 Mg ha^-1;5.2%had AGB of 400–500 Mg ha^-1,and 0.6%had AGB of>800 Mg ha^-1.Seventy percent of the areas surveyed had stand densities of 300–600 ind.ha^-1,and 64%had basal areas of 20–40 m^2 ha^-1.Precipitation is an important factor influencing the AGB of old-growth,evergreen broadleaved forests in Vietnam.Disturbances causing the loss of large-diameter trees(e.g.,>100 cm DBH)affects AGB but may not seriously affect stand density. | Tran Van Do Mamoru Yamamoto Osamu Kozan Vo Dai Hai Phung Dinh Trung Nguyen Toan Thang Lai Thanh Hai Vu Thanh Nam Trieu Thai Hung Hoang Van Thang Tran Duc Manh Cao Chi Khiem Vu Tien Lam Nguyen Quang Hung Tran Hoang Quy Pham Quang Tuyen Trinh Ngoc Bon Nguyen Thi Thu Phuong Ninh Viet Khuong Nguyen Van Tuan Dang Thi Hai Ha Tran Hai Long Dang Van Thuyet Dang Thinh Trieu Nguyen Van Thinh Tran Anh Hai Duong Quang Trung Nguyen Van Bich Dinh Hai Dang Pham Tien Dung Nguyen Huy Hoang Le Thi Hanh Phan Minh Quang Nguyen Thi Thuy Huong Hoang Thanh Son Nguyen Thanh Son Nguyen Thi Van Anh Nguyen Thi Hoai Anh Pham Dinh Sam Hoang Thi Nhung Hoang Van Thanh Nguyen Huu Thinh Tran Hong Van Ho Trung Luong Bui Kieu Hung | 2020 | Journal of Forestry Research2020，31，5： | 1 |
| 6 | Blockade of m GluR glutamate receptors in the subthalamic nucleus amelioratesmotor asymmetry in an animalmodel of Parkinsons'disease显示文摘 | Phillips JM Lam HA Ackerson LC | 2006 | Eur JNeurosci2006，23，1： | 1 |
| 7 | Design of carboxylated Fe3OJpoly(styrene-co-acrylic acid) ferrofluids with highly efficient magnetic heating effect 显示文摘 | Tai Thien Luong Thu Phuong Ha Lam Dai Tran | 2011 | Colloids and Surfaces A:Physicochemical and Engineering Aspects2011，384，： | 1 |
| 8 | A comparative analysis of risk factors and stroke risk for A sian and non‐ A sian men: The A sia P acific C ohort S tudies C ollaboration显示文摘 | Karice K. Hyun Rachel R. Huxley Hisatomi Arima Jean Woo Tai Hing Lam Hirotsugu Ueshima Xianghua Fang Sanne A. E. Peters Sun Ha Jee Graham G. Giles Federica Barzi Mark Woodward | 2013 | Int J Stroke2013，，8： | 1 |
| 9 | Blockade of mGluR glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease显示文摘 | Phillips JM Lam HA Ackerson LC | 2006 | Eur J Neurosci2006，23，1： | 1 |
| 10 | Increased gut permeability and microbiota change associate w ith mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice显示文摘 | Lam YY Ha CWY Campbell CR | 2012 | PLo S One2012，7，34： | 1 |
| 11 | Elevated tonic extracellular dopamine concentration and altered dopamine modulation of syn- aptic activity precede dopamine loss in the striatum of mice over- expressing human alpha-synuclein 显示文摘 | LAM HA WU N CELY I | 2011 | J Neurosci Res2011，89，7： | 1 |
| 12 | 泛北部湾区域贸易自由化问题研究显示文摘本文首先对贸易自由化问题进行了界定,然后就泛北部湾地区开展贸易自由化的各项因素进行了论述。一方面,笔者列举了一系列利于在该区域实现贸易自由化的潜在性因素;另一方面,笔者也注意到区域内各国基础设施条件和经济基础差异较大,贸易商品的层次不同、贸易间的关联度差以及各国在涉及国家经济安全,产业体系建立等贸易自由化政策方面所表现的不同倾向又为泛北部湾区域贸易自由化进程增添了障碍。本文在深入分析这些因素的基础上,从产业层次角度提出实现区域内贸易自由化的进程模式和方法。 | Lam Thanh Ha | 2008 | 广西金融研究2008，，1： | 1 |
| 13 | Increased gut permeability and microbiota change associate with mesenteric fat inflammation and meta- bolic dysfunction in diet-induced obese mice 显示文摘 | Lam YY Ha CW Campbell CR | 2012 | PloS One2012，7，34： | 1 |
| 14 | Atypical depressive symptoms in seasonal and non-seasonal mood disorders 显示文摘 | Tam EM Lam RW Robertson HA | 1997 | J Affect Disord1997，44，1： | 1 |
| 15 | Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice显示文摘 | Lam YY Ha CW Campbell CR | | 0，，： | 1 |
| 16 | Performance of CdS/CdSe/ZnS quantum dot-sensitized TiO_2 mesopores for solar cells显示文摘We prepare CdS/CdSe/ZnS thin films by successive ionic layer adsorption and reaction method. Results show a wider photoresponse range of TiO2 mesopores from the ultraviolet region to the visible light region. Sequentially assembled CdS/CdSe/ZnS quantum dots exhibit significantly improved light-harvesting ability and photocurrent efficiency. A high efficiency of 1.059354% is obtained. | Tung Ha Thanh Quang Vinh Lam Thai Hoang Nguyen Thanh Dat Huynh | 2013 | Chinese Optics Letters2013，11，7： | 1 |
| 17 | Increased gut permeabili- ty and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice显示文摘 | Lam Y Y Ha C W Campbell C R | 2012 | PLoS One2012，7，34： | 1 |
| 18 | Elevated tonic extracellu- lar dopamine concentration and altered dopamine modula- tion of synaptic activity precede dopamine loss in the stria- tum of mice overexpressing human ot-Synuclein显示文摘 | Lam HA Wu N Cely I | 2011 | Neu- rosci Res2011，89，7： | 1 |
| 19 | Blockade of mGluR glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson′s disease 显示文摘 | Phillips JM Lam HA Ackerson LC | 2006 | Eur J Neurosci2006，23，1： | 1 |
| 20 | Detecting Tuberculosis from Vietnamese X-Ray Imaging Using Transfer Learning Approach显示文摘Deep learning created a sharp rise in the development of autonomous image recognition systems,especially in the case of the medical field.Among lung problems,tuberculosis,caused by a bacterium called Mycobacterium tuberculosis,is a dangerous disease because of its infection and damage.When an infected person coughs or sneezes,tiny droplets can bring pathogens to others through inhaling.Tuberculosis mainly damages the lungs,but it also affects any part of the body.Moreover,during the period of the COVID-19(coronavirus disease 2019)pandemic,the access to tuberculosis diagnosis and treatment has become more difficult,so early and simple detection of tuberculosis has been more and more important.In our study,we focused on tuberculosis diagnosis by using the chestX-ray image,the essential input for the radiologist’s profession,and researched the effectiveness of the transfer learning approach in the case study of Vietnamese chest X-ray images.We proposed four strategies to clarify our hypothesis in different ways of applying transfer learning and different training set types.We also prepared a Vietnamese X-ray image dataset with the support of the VRPACS team to provide the basis for training and testing deep learning models.Our experiments were carried out by applying three different architectures,Alexnet,Resnet,and Densenet,on international,Vietnamese,and combined X-ray image datasets.After training,all models were verified on a pure Vietnamese X-rays set.The results show that transfer learning is suitable in the case study of Vietnamese chest X-ray images with high evaluating metrics in terms of AUC(Area under the Receiver Operating Characteristic Curve),sensitivity,specificity,and accuracy.In the best strategy,most of the scores were more than 0.93,and all AUCs were more than 0.98. | Ha Manh Toan Lam Thanh Hien Ngo Duc Vinh Do Nang Toan | 2023 | Computers, Materials & Continua2023，，3： | 0 |
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