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| 1 | Functional Characterization of the Apple RING E3 Ligase MdMIEL1 in Transgenic Arabidopsis显示文摘E3 ubiquitin ligases are involved in various physiological processes,and they play pivotal roles in growth and development.In this study,we identified a previously unknown gene in the apple fruit(Malus×domestica)and named it MdMIEL1.The MdMIEL1 gene encoded a protein that contained a zinc-finger domain at its N-terminus and a RING-finger motif at its C-terminus.To investigate MdMIEL1 functions,we generated transgenic Arabidopsis lines expressing the MdMIEL1 gene under the control of the Cauliflower mosaic virus 35S promoter.Interestingly,ectopic expression of MdMIEL1 in Arabidopsis produced multiple phenotypes,including early germination,early flowering and a lateral root number increase relative to wild-type plants.Further analysis indicated that MdMIEL1 regulated lateral root initiation by increasing auxin accumulation in the roots.In a word,these results suggest that,MdMIEL1 as a novel RING-finger ubiquitin ligase influences plant growth and development,and highlight that MdMIEL1 regulates lateral root growth. | AN Jianping LIU Xin SONG Laiqing YOU Chunxiang WANG Xiaofei HAO Yujin | 2017 | Horticultural Plant Journal2017，3，2： | 3 |
| 2 | 车辆悬架系统的自适应模糊控制(英文)显示文摘悬架是用来支持车身的系统,通过隔离道路干扰使得乘客感觉舒适、并确保车辆稳定.为此研究了全车模型悬架系统在下列几种控制方式下的性能:被动控制、半主动控制、自适应标准可加性模型(SAM)下的主动控制.全车模型可以为车辆悬架系统提供一些必要的性能参数,如车身偏移、车轮偏移和悬架偏斜.乘坐的舒适性和车辆的操控性决定了所需悬架系统的性能.乘坐的舒适性取决于车身偏移和乘客座位的偏移,而车辆的稳定由其他自由度(如俯仰和滚转)决定.半主动和主动悬架控制的设计通过MATLAB/SIMULINK加以实现,充分考虑了不规则的路面,并以此验证半主动控制和SAM主动控制的性能.实验结果表明,SAM主动控制能够改善乘坐的舒适性和车辆的操控性. | Khan Laiq Umair Khan M | 2012 | 中国科学技术大学学报2012，42，9： | 3 |
| 3 | Using nerve segment insert grafting to reconstruct neural pathways of brain-derived paralysis显示文摘Since 1992,task groups have used free nerve auto grafts to bridge partially transected nerves from the dominant area of the normal cerebral cortex to nerves that innervate spastic muscles from a diseased cerebral cortex,using transplanting sutures to alleviate the muscle spasm of cerebral palsy caused by different diseases. This has facilitated rebuilding of some of its neurological function. In this study,80 such patients were followed up,including 20 patients with traumatic brain injury,32 patients with stroke,and 28 pediatric patients with cerebral palsy. After postoperative follow-up of 3 to 21 years,the efficacy rate of this operation was 100% and the excellent and good spasm relief rate was 82.5%. | Wenbin Ding Shaocheng Zhang Zhuo Wang Lin Chen Chuansen Zhang Ping Huang Shunfa Liu Laiqing Sun Yuhai Ma Jun Yang Fei Huang Chengjing Xue Yanxue Zhong Lei Yin Yongtai Pan Dajiang Wu | 2017 | Translational Neuroscience and Clinics2017，3，4： | 2 |
| 4 | Enhancing anaerobic biogasification of corn stover through wet state NaOH pretreatment显示文摘 | Mingxia Zheng Xiujin Li Laiqing Li Xiaojin Yang Yanfeng He | 2009 | Bioresource Technology2009，，21： | 2 |
| 5 | Abernethy malformation type Ⅱwith nephrotic syndrome and other multisystemic presentation:an illustrative case for understanding pathogenesis of extrahepatic complication of congenital portosystemic shunt显示文摘 | Schaeffer DF Laiq S Jang H J | | 0，，03： | 1 |
| 6 | EDDS and EDTA-enhanced photoextraction of metals from artificiaily contaminated soil and residual effects of chelant compounds 显示文摘 | Chunling Luo Zhenguo Shen Laiqing Luo | 2006 | Environmental Pollution2006，144，： | 1 |
| 7 | Functional identification of MdSMXL8.2,the homologous gene of strigolactones pathway repressor protein gene in Malus×domestica显示文摘A homologous gene of strigolactones repressor protein gene SMXL7/D53,MdSMXL8.2(GenBank accession No.:MD07G1222400),was cloned from‘Royal Gala’apple(Malus×domestica Borkh.)in this study.The sequence analysis revealed that the length of this gene was 3243 bp,which encoded 1080 amino acids,and had a protein molecular mass of∼110 kD.The phylogenetic tree analysis indicated that the MdSMXL8.2 exhibited the highest sequence similarity with Arabidopsis AtSMXL7.The protein conserved domain analysis revealed that the MdSMXL8.2 contained two ClpA domains.The prediction of the secondary and tertiary structures of the MdSMXL8.2 indicated that it contained 34.54%αhelix,3.43%β-sheet,and 11.76%extended chain.The in-silico analysis suggested that the promoter sequence of MdSMXL8.2 contained several typical cisacting elements,including abscisic acid(ABA),gibberellin(GA),ethylene,auxin,jasmonic acid(JA),salicylic acid(SA),drought,and heat stressresponsive elements.Quantitative real-time(qRT)-PCR analyses revealed that MdSMXL8.2 was expressed in different apple tissues,with the highest transcript level found in the stem.The expression of MdSMXL8.2 was significantly induced by exogenous ABA,PEG and mannitol,while exogenous NaCl significantly inhibited MdSMXL8.2 expression.The growing status of MdSMXL8.2-overexpressed Orin apple callus was worse than the wild type(WT)after NaCl treatment and had a higher malondialdehyde(MDA)content and relative conductance(REC).Additionally,MdSMXL8.2-overexpressed Arabidopsis exhibited shorter root length and a reduction in fresh weight under salt stress,indicating that MdSMXL8.2 negatively regulated salt tolerance in apples. | Weijian Sun Xinglong Ji Laiqing Song Xiaofei Wang Chunxiang You Yujin Hao | 2021 | Horticultural Plant Journal2021，7，4： | 1 |
| 8 | The frequency of postduralpuncture headache in different age groups 显示文摘 | Wadud R Laiq N Qureshi FA | 2006 | J Coll PhysiciansSurg Pak2006，16，： | 1 |
| 9 | Comparison of caudal bupivacaine and bupivacaine-tramadol for postoperative analgesia in children undergoing hypospadias surgery显示文摘 | Laiq N Khan MN Tahmeedull AH | 2009 | J Coil Physicians Surg Pak2009，19，11： | 1 |
| 10 | Transformer-Based Deep Learning Network for Tooth Segmentation on Panoramic Radiographs显示文摘Panoramic radiographs can assist dentist to quickly evaluate patients’overall oral health status.The accurate detection and localization of tooth tissue on panoramic radiographs is the first step to identify pathology,and also plays a key role in an automatic diagnosis system.However,the evaluation of panoramic radiographs depends on the clinical experience and knowledge of dentist,while the interpretation of panoramic radiographs might lead misdiagnosis.Therefore,it is of great significance to use artificial intelligence to segment teeth on panoramic radiographs.In this study,SWin-Unet,the transformer-based Ushaped encoder-decoder architecture with skip-connections,is introduced to perform panoramic radiograph segmentation.To well evaluate the tooth segmentation performance of SWin-Unet,the PLAGH-BH dataset is introduced for the research purpose.The performance is evaluated by F1 score,mean intersection and Union(IoU)and Acc,Compared with U-Net,Link-Net and FPN baselines,SWin-Unet performs much better in PLAGH-BH tooth segmentation dataset.These results indicate that SWin-Unet is more feasible on panoramic radiograph segmentation,and is valuable for the potential clinical application. | SHENG Chen WANG Lin HUANG Zhenhuan WANG Tian GUO Yalin HOU Wenjie XU Laiqing WANG Jiazhu YAN Xue | 2023 | Journal of Systems Science & Complexity2023，36，1： | 1 |
| 11 | Dexamethasone as antiemetic during gynaecological laparoscopic surgery显示文摘 | Laiq N Khan MN Qureshi FA | 2005 | J Coll Physicians Surg Pak2005，15，12： | 1 |
| 12 | Postoperativeobservationandnursingcareofcomplicationsofdigitalsubtractioncerebralangiog-raphyandinterventionaltherapy[J]显示文摘 | DENGHH LAIQ ZHOUXJ | | 实用神经疾病杂志0，，： | 1 |
| 13 | Enhancing anaerobic biogasification of corn stover through wet stateNaOH pretreatment显示文摘 | Zheng Mingxia Li Xiujin Li Laiqing | 2009 | Bioresource Technology2009，100，21： | 1 |
| 14 | En- hancing anaerobic biogasification of corn stover through wet state NaOH pretreatment显示文摘 | MINGXIA ZHENG XIUJIN LI LAIQING LI l | 2009 | Bioresource Technol- ogy2009，100，21： | 1 |
| 15 | Enhancing anaerobic bio gasification of corn stover through wet state NaOH pretreatment 显示文摘 | ZHENG MINGXIA LI XIUJIN LI LAIQING | 2009 | Bioresource Technology2009，100，21： | 1 |
| 16 | Enhancing anaerobic biogasification of corn stover through wet state NaOH pretreatment显示文摘 | Zheng Mingxia Li Xiujin Li Laiqing | | 0，，21： | 1 |
| 17 | Abernethy malformation type II with nephrotic syndrome and other multisystemic presentation:An illustrative case for understanding pathogenesis of extrahepatic complication of congenital portosystemic shunt显示文摘 | Schaeffer DF Laiq 8 Jang HJ | 2015 | Human Pathology2015，44，3： | 1 |
| 18 | Enhancing anaerobic biogasification of corn stover through wet state NaOH pretreatment显示文摘 | Zheng Mingxia Li Xiujin Li Laiqing | 2009 | Bioresource Technology2009，100，15： | 1 |
| 19 | The copper tolerance mechanisms of Elsholtzia haichowensis, a plant from copper-enriched soils显示文摘 | LOU laiqing SHEN zhenguo LI xiangdong | 2004 | Environmental Experiment Botany2004，51，2： | 1 |
| 20 | 显示文摘 | Laiq H Marijn K Zaid A | 2011 | BMC Re-search Notes2011，4，1： | 1 |
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