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245篇 您的检索式:作者名="Laing PS"
    题名 作者 年代 出处 被引量
1美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) 2012中华神经科杂志2012,45,5:22
22013年美国心脏病学会/美国心脏协会胆固醇管理指南在美国心脏病学实践中的应用显示文摘2013年美国心脏病学会/美国心脏协会(American College of Cardiology/American Heart Association,ACC/AHA)胆固醇管理指南建议在符合治疗标准的患者中采用中等强度至高强度他汀类药物治疗。该研究的目的在于审查2013年ACC/AHA指南在美国心脏病学实践中的应用情况。刘莉 叶鹏 Pokharel Y Tang F Jones PG Nambi V Bittner VA Hira RS Nasir K Chan PS Maddox TM Oetgen WJ Heidenreich PA Borden WB Spertus JA Petersen LA Ballantyne CM Virani SS 2017中华高血压杂志2017,25,6:2
3Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation显示文摘Liotta LA Steeg PS Shetler-Stevenson WG 1991Cell1991,64,2:2
4Cancer invasion and metastasis : positive and negative regulatory elements显示文摘Liotta LA Stetler-Stevenson WG Steeg PS 1991Cancer Invest1991,9,5:1
5Cancer metastasis and angiogensis:an imbalance of positive and negative regulation显示文摘Liotta LA Steeg PS Stetlerstevenson WG 1991Cell1991,64,2:1
6Toward defining the preclinical stages of Alzheimer's disease:recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘Sperling RA Aisen PS Beckett LA 2011Alzheimers Dement2011,7,3:1
7Toward defining the preclinical stages of Alzheimer' s disease:recommendations from the National Institute on Aging-Alzheimer' s Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘Sperling RA Aisen PS Beckett LA 0,,03:1
8Complement activation and clearance in acute illness and injury:evidence for C5a as a cell-directed mediator of the adult respiratory distress syndrome in man显示文摘Solomkin JS Cotta LA Satoh PS 1985Surgery1985,97,6:1
9Cancer metastasis and angiogenesis:an inbalance of positive and negative regulation显示文摘 Steeg PS Sterler-Steveson WG 1991Cell1991,64,2:1
10Characterization of MRI response to treatment with interferon beta-1b: contrast-enhancing MRI lesion frequency as a primary outcome measure显示文摘 FRANK JA ALBERT PS 1997Neurology1997,49,3:1
11Tears of the annulus fibrosus:correlation between MR and pathologic findings in cadavers显示文摘 Sether LA Ho PS 1988AJNR Am J Neuroradio1988,9,:1
12The potential role of nm23 in cancer metastasis and cellular differentiation显示文摘MacDonald N J de la Rosa A Steeg PS 1995Eur J Cancer1995,31,78:1
13Cancer metastasis and angiogenesis:an inbalance of positive and negative regulation 显示文摘Lotta LA steeg Ps settler- stevenson WG 1991Cell1991,64,:1
14Clinical differences a- mong patients treated for mental health problems in general medical and specialty mental health settings in the National Comorbidity Survey Rep-lication 显示文摘Uebelaeker LA Wang PS Berglund P 2006Gen Hosp Psychiatry2006,28,5:1
15CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice 显示文摘Olofsson PS Stiderstrm LA Whgsater D 2008Circulation2008,117,10:1
16CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypereholesterolemic mice显示文摘PS Olofsson LA Soderstrom D Wagsater 2008Circulation2008,117,10:1
17Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation显示文摘Liotta LA steeg PS Stetler - Steveson WG 1991Cell1991,151,5:1
18Cancer metastasis and angiogenesis : imbalance of positive and negative regulation 显示文摘Liotta LA Steeg PS Stetler-Stevenson WG 1991Cell1991,64,2:1
19Toward defining the preclinical stages of Alzheim-er's disease:Recommendations from the National Institute on Aging-Alzheimer's Associat-ion workgroups on diagnostic guidelines for Alzheimer's disease显示文摘Sperling RA Aisen PS Beckett LA 2011Alzheimer''s dement2011,7,3:1
20Toward defining the preclinical stages of Alzheimer's disease:Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease显示文摘Sperling RA Aisen PS Beckett LA 0,,03:1
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