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| 1 | Optimal central venous pressure during partial hepatectomy for hepatocellular carcinoma显示文摘BACKGROUND:Low central venous pressure(CVP) affects hemodynamic stability and tissue perfusion.This prospective study aimed to evaluate the optimal CVP during partial hepatectomy for hepatocellular carcinoma(HCC).METHODS:Ninety-seven patients who underwent partial hepatectomy for HCC had their CVP controlled at a level of 0 to 5 mmHg during hepatic parenchymal transection.The systolic blood pressure(SBP) was maintained,if possible,at 90 mmHg or higher.Hepatitis B surface antigen was positive in 90 patients(92.8%) and cirrhosis in 84 patients(86.6%).Pringle maneuver was used routinely in these patients with clamp/unclamp cycles of 15/5 minutes.The average clamp time was 21.4±8.0 minutes.These patients were divided into 5 groups based on the CVP:group A:0-1 mmHg;B:1.1-2 mmHg;C:2.1-3 mmHg;D:3.1-4 mmHg and E:4.1-5 mmHg.The blood loss per transection area during hepatic parenchymal transection and the arterial blood gas before and after liver transection were analyzed.RESULTS:With active fluid load,a constant SBP ≥90 mmHg which was considered as optimal was maintained in 18.6% in group A(95% CI:10.8%-26.3%);39.2% in group B(95% CI:29.5%-48.9%);72.2% in group C(95% CI:63.2%-81.1%);89.7% in group D(95% CI:83.6%-95.7%);and 100% in group E(95% CI:100%-100%).The blood loss per transection area during hepatic parenchymal transection decreased with a decrease in CVP.Compared to groups D and E,blood loss in groups A,B and C was significantly less(analysis of variance test,P<0.05).Compared with the baseline,the blood oxygenation decreased significantly when the CVP was reduced.Base excess and HCO 3-in groups A and B were significantly decreased compared with those in groups C,D and E(P<0.05).CONCLUSION:In consideration of blood loss,SBP,base excess and HCO 3-,a CVP of 2.1-3 mmHg was optimal in patients undergoing partial hepatectomy for HCC. | Cheng-Xin Lin Ya Guo Wan Yee Lau Guang-Ying Zhang Yi-Ting Huang Wen-Zheng He Eric CH Lai | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 19 |
| 2 | Effectiveness of Different Waist Circumference Cut-off Values in Predicting Metabolic Syndrome Prevalence and Risk Factors in Adults in China显示文摘Objective To study the effectiveness of waist circumference cut-off values in predicting the prevalence of metabolic syndrome(MetS) and risk factors in adults in China. Methods A cross-sectional survey was condcuted in 14 provinces(autonomous region, municipality) in China. A total of 47 325 adults aged ≥20 years were selected by multistage stratified sampling, and questionnaire survey and physical and clinical examination were conducted among them. MetS was defined according to the International Diabetes Federation(IDF) criteria and modified IDF criteria.Results The age-standardized prevalence of MetS was 24.2%(22.1% in men and 25.8% in women) and 19.5%(22.1% in men and 18.0% in women) according to the IDF criteria and modified IDF criteria respectively. The age-standardized prevalence of pre-MetS was 8.1%(8.6% in men and 7.8% in women) according to the modified IDF criteria. The prevalence of MetS was higher in urban residents than rural residents and in northern China residents than in southern China residents. The prevalence of central obesity was about 30% in both men and women according to the ethnicity-specific cut-off values of waist circumference for central obesity(90 cm for men and 85 cm for women). Multivariate regression analysis revealed no significant difference in risk factors between the two MetS definitions. Conclusion Using both the modified IDF criteria and ethnicity-specific cut-off values of waist circumference can provide more useful information about the prevalence of MetS in China. | ZHOU Hai Cheng LAI Ya Xin SHAN Zhong Yan JIA Wei Ping YANG Wen Ying LU Ju Ming WENG Jian Ping JI Li Nong LIU Jie TIAN Hao Ming JI Qiu He ZHU Da Long CHEN Li GUO Xiao Hui ZHAO Zhi Gang Li Qiang ZHOU Zhi Guang GE Jia Pu SHAN Guang Liang | 2014 | Biomedical and Environmental Sciences2014，27，5： | 17 |
| 3 | Microsatellite instability,MMR gene expression and proliferation kinetics in colorectal cancer with famillial predisposition显示文摘INTRODUCTIONGenetic instability is a conunon property of manyhuman cancers,including those of HNPCC.A novel form of genetic instability involving somaticalterations,such as deletions and insertions insimple repeated sequences,has been found.Microsatellitcs are relatively short runs of tandemlyrepeated sequences scattered throughout | Bao Ping Wu Ya Li Zhang Dian Yuan Zhou Chun Fang Gao Zhuo Sheng Lai | 2000 | World Journal of Gastroenterology2000，6，6： | 14 |
| 4 | Inducible overexpression of RUNX1b/c in human embryonic stem cells blocks early hematopoiesis from mesoderm显示文摘RUNX1 绝对为 RUNX1b/c 的权威的造血作用,而是功能被要求,人的 RUNX1 的二 isoforms,是不清楚的。我们建立了可诱导的 RUNX1b/c-overexpressing 人的胚胎的干细胞(hESC ) 线,在 RUNX1b/c, overexpression 阻止了 CD34+ 房间的出现早舞台,急速地从而减少造血的干细胞的生产。同时,造血作用相关的因素的表示是 downregulated。然而,如此的阻塞效果从在 hESC/AGM-S3 房间合作文化的白天 6 消失了,证明阻塞发生在 hemogenic endothelial 房间的产生前。这阻塞被 RepSox 部分救,转变生长因素(TGF ) 的一个禁止者 - 发信号的小径,显示在 RUNX1b/c 和 TGF- 小径之间的一种靠近的关系。我们的结果在早造血作用的开发建议 RUNX1b/c 的一个唯一的禁止的函数并且可以在正常和 diseased 模型帮助它的生物函数的进一步的理解。 | Bo Chen Jiawen Teng Hongwei Liu Xu Pan Ya Zhou Shu Huang Mowen Lai Guohui Bian Bin Mao Wencui Sun Qiongxiu Zhou Shengyong Yang Tatsutoshi Nakahata Feng Ma | 2017 | Journal of Molecular Cell Biology2017，9，4： | 3 |
| 5 | Panda X-III: Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers显示文摘Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation experiments.Panda X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 bar.Fine pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the middle.Charge signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial resolution.The detector will be immersed in a large water tank to ensure~5 m of water shielding in all directions.The second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds. | Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，6： | 2 |
| 6 | Synthesis and evaluation of nitrate derivatives of colchicine as anticancer agents显示文摘到为更多的有势力 antitumor 代理人的搜索,一系列新奇氮的捐赠氧化物的用番红花作原料而制成的植物盐基(关口) 衍生物(6af, 8a 和 b ) 被与 N 甲基 colchiceinamide 联合硝酸盐综合。他们对在 vitro 的四根人的癌症房间线的 cytotoxicity 被 MTT 试金评估。它特别地,显示的重要活动加重的衍生物被发现那许多 6c, 8a 和 8b 显示出更多的有势力细胞毒素的活动比关口。 | Li Hong Shen Ya Li Da Hai Zhang Yi Sheng Lai Li Jie Liu | 2011 | Chinese Chemical Letters2011，22，7： | 2 |
| 7 | Randomized Trial of Endoscopic Sphincterotomy With Balloon Dilation Versus Endoscopic Sphincterotomy Alone for Removal of Bile Duct Stones显示文摘 | Anthony Yuen Bun Teoh Frances Ka Yin Cheung Bing Hu Ya Min Pan Larry Hin Lai Philip Wai Yan Chiu Simon Kin Hung Wong Francis Ka Leung Chan James Yun Wong Lau | 2013 | Gastroenterology2013，，： | 2 |
| 8 | Novel 6-bp Deletion Mutation in visfatin Gene and Its Associations with Birth Weight and Bodyweight in Chinese Cattle显示文摘Visfatin, like insulin, induces phosphorylation of signal transduction proteins that operatate downstream of the insulin receptor. The present study is focused on detecting deletion of visfatin gene and analyzing its effect on growth traits in six Chinese cattle breeds (Nangyang, Luxi, Qinchuan, Jiaxian Red, Grassland Red, and Chinese Holstein) using DNA sequencing, PCR-SSCP and PCR-RFLP methods. For the first time, a 6-bp deletion of visfatin was described and two alleles were revealed:W and D. The χ2-test analysis demonstrated that all breeds were in agreement with Hardy-Weinberg equilibrium (P>0.05). The associations of the novel 6-bp deletion of visfatin gene with growth traits of Nanyang cattle at 6-, 12-, 18-, and 24-mon-old were analyzed. Birth weight, 12- and 24-mon-old cattle with genotype WW had greater birth weight and average daily gain than genotype WD (P<0.01 or P<0.05). These results suggest that the deletion may influence the birth weight and bodyweight in 12 mon-old cattle. | WANG Mou ZHANG Ya YU Hui LAI Xin-sheng ZHU Jin-long JIAO Jin-zhen LAN Xian-yong LEI Chu-zhao ZHANG Liang-zhi CHEN Hong | 2012 | Journal of Integrative Agriculture2012，11，8： | 1 |
| 9 | Laser annealing of SiO2 film deposited by ICPECVD for fabrication of silicon based low loss waveguide显示文摘硅二氧化物退火的激光(诱导地联合的血浆形成的 SiO 2) 电影提高了化学蒸汽免职(ICPECVD ) 为低损失硅的制造被学习基于的波导。激光在扔 ICPECVD 的 SiO 2 电影上退火的影响被调查。表面粗糙,折射索引,并且蚀刻退火的样品的率与 2 电影由热氧化获得了的 SiO 的那些相比。扔 ICPECVD 的 SiO 2 电影的表演能被激光退火显著地改进,这被表明。艾尔 2 O 3/SiO2 波导与更低的 cladding 由 ICPECVD 和激光退火过程形成了的 SiO 2 在硅底层上被制作了,并且它的繁殖损失被发现与有热地氧化的更低的 cladding 的波导的可比较。 | Ya'nan WANG Yi LUO Changzheng SUN Bing XIONG Jian WANG Zhibiao HAO Yanjun HAN Lai WANG Hongtao LI | 2016 | Frontiers of Optoelectronics2016，9，2： | 1 |
| 10 | An endogenous growth model of capital and arms accumulation显示文摘 | Shieh Jhy Yuan Wen Ya Chang Ching Chong Lai | 2007 | Defence and Peace Economics2007，18，： | 1 |
| 11 | Randomized Trial of Endoscopic Sphincterotomy With Balloon Dilation Versus Endoscopic Sphincterotomy Alone for Removal of Bile Duct Stones显示文摘 | Anthony Yuen Bun Teoh Frances Ka Yin Cheung Bing Hu Ya Min Pan Larry Hin Lai Philip Wai Yan Chiu Simon Kin Hung Wong Francis Ka Leung Chan James Yun Wong Lau | 2013 | Gastroenterology2013，，： | 1 |
| 12 | Stability of tea theaflavins and catechins 显示文摘 | Ya Lun Su Lai Kwok Leung Yu Huang | 2003 | Food Chemistry2003，，83： | 1 |
| 13 | Baicalein induces proliferation inhibition in B16F10 melanoma cells by generating reactive oxygen species via 12-lipoxygenase显示文摘 | Chou DS Hsiao G Lai YA Tsai YJ Sheu JR | 2009 | Free Radic Biol Med2009，46，8： | 1 |
| 14 | Evaluation of nine major satellite soil moisture products in a typical subtropical monsoon region with complex land surface characteristics显示文摘Assessing accuracies of satellite soil moisture(SM)products in areas with strong anthropogenic activities,abundant precipitation,and dense vegetation is important but limited.In this study,performances of nine satellite SM products,including the European Space Agency Climate Change Initiative(ESA CCI),and the ascending and descending products of the Advanced Microwave Scanning Radiometer 2(AMSR2),Chinese Fengyun-3B(FY3B),Chinese Fengyun-3C(FY3C),and Soil Moisture Active Passive(SMAP),were evaluated against in-situ SM in the Yangtze River Delta(YRD)from 2015 to 2018.Results showed that the ESA CCI outperformed other products,with averaged correlation coefficient(R)of 0.522,correlation coefficient for SM anomalies(Rano)of 0.419,and unbiased root mean square error(ubRMSE)of 0.040 m^(3)m^(-3),followed by the SMAP_A and SMAP_D.Overestimation was observed in the AMSR2 products(Bias>0.081 m^(3)m^(-3)),while underestimation was found in the FY3B and FY3C products(Bias<-0.104 m^(3)m^(-3)).Moreover,R values decreased with the increase in water area percentage(WAP),land cover heterogeneity(GSI),fractional vegetation cover(FVC),and precipitation(PRE).Threshold values were observed at 3%for the WAP,0.05 for the FVC,and 900 mm yr^(-1)for the PRE,below which sharp declines of accuracy were observed.The WAP,GSI,and FVC were divided into five sub-classes with their values increasing with the sub-class level(I to V).Correlations coefficients between these perturbing factors and R(correlation between satellite and in-situ SM)increased as sub-class levels increased.Under sub-classes I,II,and III,these three factors had limited influences on accuracies of satellite SM products.However,under sub-classes IV and V,significant impacts of these three perturbing factors were observed.Moreover,when sub-classes of the PRE increased from I to V,correlations between Bias and PRE decreased first and then increased.These findings can help to determine suitable satellite SM products in the YRD and similar areas. | Liuyang Li Ya Liu Qing Zhu Kaihua Liao Xiaoming Lai | 2022 | International Soil and Water Conservation Research2022，10，3： | 1 |
| 15 | Registration and data merging for multiple sets of sean data 显示文摘 | Lai J Y Ueng W D Ya C Y | 1999 | The International Journal of Machine Tools Manufacturing Technology1999，15，： | 1 |
| 16 | Severe vitreous hemorrhage associated with closed-globe injury显示文摘 | Ling Yeung Tun Lu Chen Ya Hui Kuo An Ning Chao Wei Chi Wu Kuan Jen Chen Yih Shiou Hwang Yen Po Chen Chi Chun Lai | 2006 | Graefe’s Archive for Clinical and Experimental Ophthalmology2006，，1： | 1 |
| 17 | Relative bcl-2 independence of drug induced cytotoxicity and resistance in 518 Amelanoma cells显示文摘 | Benimetska YA L Lai JC Khvorova A | 2004 | Clin Cancer Res2004，10，： | 1 |
| 18 | Reproducibility ofregional placental vascularity/perfusion measurementusing 3D power doppler显示文摘 | LAI PK WANG YA WELSH AW | 2010 | Ultrasound Obstet Gynecol2010，36，2： | 1 |
| 19 | A M?ssbauer investigation of nano-NiFe alloy/expanded graphite for electromagnetic shielding显示文摘A new material is prepared by impregnating the expanded graphite(EG) into ethanol solutions of metal acetate and then drying and reducing it in H2.It contains the EG and the nanoparticles of the magnetic Ni–Fe alloy for the electromagnetic shielding.Its morphology,phase structure,magnetic properties,and electromagnetic shielding effectiveness(SE) are investigated in our experiment.It shows that the morphology,the phase structure,and the magnetic property of the composite can be modified by altering the Ni content in the alloy nanoparticles.Interestingly,the SE can be enhanced to 54–70 d B at low frequencies(300 kHz–10 MHz) by dispersing the magnetic nanoparticles onto EG. | Wei Liu Yu-An Huang Lai Wei Ya Zhai Rui-Li Zhang Tao Tang Run-Sheng Huang | 2016 | Nuclear Science and Techniques2016，27，6： | 1 |
| 20 | Correlation between the expression of divalent metal transporter 1 and the content of hypoxia-inducible factor-1 in hypoxic HepG2 cells 显示文摘 | Li Z Lai Z Ya K | 2008 | J Cell Mol Med2008，12，2： | 1 |
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