|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | ORYZA2000模型模拟北京地区旱稻的适应性初探显示文摘利用北京昌平2年旱稻田间试验结果,对ORYZA2000模型模拟旱稻生长发育的适应性做了初步研究。根据2003年旱稻田间试验结果,对模型进行调试,获得了旱稻的基本作物参数,包括旱稻不同生育阶段的发育速率、干物质分配系数、比叶面积、最大根深等。利用2002年的数据对模型模拟的生物量、叶面积和产量等结果进行了检验。结果表明,ORYZA2000能够比较准确地模拟旱稻的生物量、叶面积动态变化过程及最终产量,尤其是在模拟穗生物量方面具有较高的准确性。地上部总生物量、绿叶生物量、茎生物量、穗生物量、叶面积指数和产量的相对均方根误差NRMSE值分别为45%、35%、57%、37%、35%和23%。 | 薛昌颖 杨晓光 BAM Bouman 冯利平 Gon van Laar 王化琪 王璞 王志敏 | 2005 | 作物学报2005，31，12： | 34 |
| 2 | 可满足高炉严格使用要求的高性能MTT金属管铸铜冷却壁显示文摘达涅利康力斯推出一种新的冷却概念,它将铜冷却壁与浇铸在其中的蒙乃尔铜-镍合金管结合为一个整体。蒙乃尔铜-镍合金管构成冷却水通道。它不仅可使冷却水拥有一条光滑的无泄漏通道,而且具有足够的尺寸灵活性,以满足躲避现有高炉炉壳开口的要求,还可以省去在高炉炉壳内的任何焊接。 | E.van Stein Callenfels R.van Laar | 2007 | 钢铁2007，42，3： | 9 |
| 3 | APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells显示文摘Amyloid beta(Aβ)precursor protein(APP)is a key protein in the pathogenesis of Alzheimer’s disease(AD).Both APP and its paralogue APLP1(amyloid beta precursor-like protein 1)have multiple functions in cell adhesion and proliferation.Previously it was thought that autophagy is a novel beta-amyloid peptide(Aβ)-generating pathway activated in AD.However,the protein proteolysis of APLP1 is still largely unknown.The present study shows that APLP1 is rapidly degraded in neuronal cells in response to stresses,such as proteasome inhibition.Activation of the endoplasmic reticulum(ER)stress by proteasome inhibitors induces autophagy,causing reduction of mature APLP1/APP.Blocking autophagy or JNK stress kinase rescues the protein expression for both APP and APLP1.Therefore,our results suggest that APP/APLP1 is degraded through autophagy and the APLP1 proteolysis is mainly mediated by autophagy-lysosome pathway. | Fangfang Zhou Theo van Laar Huizhe Huang Long Zhang | 2011 | Protein & Cell2011，2，5： | 8 |
| 4 | Intense immunosuppression and stem- cell transplantation for patients with severe rheumatic autoimmune disease a review 显示文摘 | Van Laar JM Tyndall A | 2003 | Cancer Control2003，10，： | 1 |
| 5 | Components of health:an analysis in rheumatoid arthritis using quality of life questionnaires and clinical and laboratory variables显示文摘 | Borstlap M Laar M Zant J | 1993 | Ann Rheum Dis1993，52，： | 1 |
| 6 | By any means necessary: Theeffects ofregula- tory focus and moral conviction on hostile and benevolent forms of collectiveaction 显示文摘 | ZAAL M P VAN LAAR C STHAL T ELLEMERS N DERKS B | 2011 | British Journal of Social Psychology2011，50，： | 1 |
| 7 | Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson’s disease(NSTAPS study):a randomised controlled trial显示文摘 | Odekerken V J van Laar T Staal M J | 2013 | Lancet Neurol2013，12，1： | 1 |
| 8 | Proteomic analysisof rat brain mitochondria following exposure to dopaminequinine:implications for Parkinson disease显示文摘 | Van Laar VS Dukes AA Cascio M | 2008 | NeurobiolDis2008，29，3： | 1 |
| 9 | Blast Furnace Hearth Management for Safe and Long Campaigns显示文摘 | Laar R V Callenfels E S Geerdes M | 2003 | Iron and Steel Maker2003，，8： | 1 |
| 10 | The ‘school of de Wit'crop growth simulation models:A pedigree and historical overview显示文摘 | Bouman B A M Keulen H van Laar H H van | 1996 | Agricultural System1996，52，： | 1 |
| 11 | Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB显示文摘 | Douma S Van Laar T Zevenhoven J | 2004 | Nature2004，430，7003： | 1 |
| 12 | The effect of university roommate contact on ethnic attitudes and behavior显示文摘 | Colette Van Laar Shana Levin Stacey Sinclair Jim Sidanius | 2004 | Journal of Experimental Social Psychology2004，，4： | 1 |
| 13 | Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis显示文摘 | Maarten Boers Arco C Verhoeven Harry M Markusse Mart AFJ van de Laar Rene Westhovens J Christiaan van Denderen Derkjen van Zeben Ben AC Dijkmans Andre J Peeters Piet Jacobs Hans R van den Brink Hubert JA Schouten Désirée MFM van der Heijde Annelies Boonen | 1997 | The Lancet1997，，9074： | 1 |
| 14 | The role of feed consumption and feed efficiency in copper-stimulated growth 显示文摘 | Zhou W kornegay E T Van Laar H | 1994 | J Anim Sci1994，72，： | 1 |
| 15 | The fetal variant of the circle of Willis and its influence on the cerebral collateral circulation 显示文摘 | Van Raamt AF Mali WP Van Laar PJ | 2006 | Cerebrovasc Dis2006，22，4： | 1 |
| 16 | Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain显示文摘 | Pergolizzi JV Jr van de Laar M Langford R | 2012 | J Pain Res2012，5，： | 1 |
| 17 | 难治性类风湿关节炎的临床特点:一项国际问卷调查研究显示文摘目的尽管按照目前欧洲抗风湿联盟(EULAR)的推荐对类风湿关节炎(rheumatoid arthritis,RA)患者进行治疗,难治性RA患者的临床症状却仍然没有得到完全控制,目前EULAR指南主要关注的是RA的早期治疗和药物治疗。本研究的目的在于分析难治性RA患者的临床特点,以及在患者管理中需要探索然而现有EULAR指南并未涉及的问题。方法对多个国家的风湿科医生进行问卷调查,分析难治性RA的临床特点。问卷包括多选题以及开放性问题,从开放性问题的回答中发现需要进一步阐明的问题以及现有EULAR指南需要增加的内容。结果410名受访者完成了调查问卷,关于难治性RA的特点:50%受访者认为基于28个关节评估的疾病活动评分(disease activity score assessing 28 joints,DAS28)>3.2或存在疾病活动的征象;42%受访者认为疲劳是其特点;48%认为至少两种传统合成改变病情抗风湿药(DMARDs)以及使用至少两种生物制剂或靶向合成DMARDs治疗失败;89%认为糖皮质激素不能减量到5 mg/天或泼尼松不能减量到10 mg/天或同等剂量的其他激素。另外,现有EULAR指南中应增加合并症和关节外表现的干预以及多种药物联合治疗等重要内容。结论目前风湿科医生对难治性RA的定义有很大争议。难治性RA患者的很多重要问题目前EULAR指南中均没有涉及。 | Nadia MT Roodenrijs Maria J H de Hair Marlies C van der Goes Johannes WG Jacobs Paco MJ Welsing Désirée van der Heijde Daniel Aletaha Maxime Dougados Kimme L Hyrich Iain B McInnes Ulf Mueller-Ladner Ladislav Senolt Zoltan Szekanecz Jacob Mvan Laar Nagy Gyorgy 黄艳荣(译) 张卓莉(审校) | 2019 | 英国医学杂志中文版2019，22，2： | 1 |
| 18 | Increase in HCV incidence among men who have sex with men in Amsterdam most likely caused by sexual transmission显示文摘 | van de Laar TJ van der Bij AK Prins M | 2007 | J Infect Dis2007，196，2： | 1 |
| 19 | Stimulation of gap junctional communication:comparison of acycloretionic acid lycopene 显示文摘 | Stahl W von laar J Martin H D etal | 2000 | Arch Biochem Biophys2000，373，： | 1 |
| 20 | Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries 显示文摘 | Hamers FP Lankhorst AJ van Laar TJ | 2001 | J Neurotrauma2001，18，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员