维普期刊资源整合服务平台（V6.5）

144篇 您的检索式：作者名="LUKAS H"

选中清除导出查看参考文献查看引证文献引用追踪共8页首页上一页第1页下一页末页 /8 跳转

	题名	作者	年代	出处	被引量
1	Role of HSP-90 for increased nNOS-mediated vasodilation in mesenteric arteries in portal hypertension显示文摘AIM:To explore the role of heat shock protein-90 (HSP-90) for nitrergic vasorelaxation in the splanchnic circulation in rats with and without portal hypertension. METHODS: Neuronal nitric oxide synthase (nNOS) and HSP-90 were analyzed by immunofluorescence, western blotting and co-immunoprecipitation in the mesenteric vasculature and isolated nerves of portal-vein-ligated (PVL) rats and sham operated rats. In vitro perfused de-endothelialized mesenteric arterial vasculature was preconstricted with norepinephrine (EC80) and tested for nNOS-mediated vasorelaxation by periarterial nerve stimulation (PNS, 2-12 Hz, 45V) before and after incubation with geldanamycin (specific inhibitor of HSP-90 signalling, 3 μg/mL) or L-NAME (non-specific NOSblocker, 10-4 mol/L). RESULTS: nNOS and HSP-90 expression was significantly increased in mesenteric nerves from PVL as compared to sham rats. Moreover, nNOS and HSP-90 were visualized in mesenteric nerves by immunofluorescence and immunoprecipitation of nNOS co-immunoprecitated HSP-90 in sham and PVL rats. PNS induced a frequencydependent vasorelaxation which was more pronounced in PVL as compared to sham rats. L-NAME and geldanamycin markedly reduced nNOS-mediated vasorelaxation abrogating differences between the study groups. The effect of L-NAME and geldanamycin on nNOS-mediated vasorelaxation was significantly greater in PVL than in sham animals. However, no difference in magnitude of effect between L-NAME and geldanamycin was noted. CONCLUSION: HSP-90 acts as a signalling mediator of nNOS-dependent nerve mediated vascular responses in mesenteric arteries, and the increased nitrergic vasorelaxation observed in portal hypertension is mediated largely by HSP-90.	Lukas Moleda Lars Jurzik Matthias Froh Erwin Gbele Claus Hellerbrand Rainer H Straub Jürgen Schlmerich Reiner Wiest	2010	World Journal of Gastroenterology2010，16，15：	4
2	Cyclin D1 expression is regulated by the retinoblastoma protein显示文摘	MULLER H LUKAS J SCHNEIDER A	2004	Proc Natl Acad Sci U S A2004，91，8：	1
3	An empirical analysis of the brand personality effect显示文摘	Traci H F Lukas P F	2005	Journal of Product & Brand Management2005，14，7：	1
4	Phase relations in the samarium-poor Sm-Co-Fe system 显示文摘	Schneider G Henig E -Th Lukas H L	1985	J Less-Common Met1985，110，：	1
5	Scoring inflammatory activity of the spine by magnetic resonance imaging in ankylosingspondylitis: a multireader experiment 显示文摘	LUKAS C BRAUN J VAN DER H D	2007	The Journal of Rheumatology2007，34，4：	1
6	Cyclin D1 protein expression and function in human breast cancer 显示文摘	Bartkova J Lukas J Muller H	1994	Int J Cancer1994，57，3：	1
7	Column extraction of heavy metals from soils using biodegradable chelating agent EDDS显示文摘	Lukas H Susan T Rainer S	2005	Environ Sci Technol2005，39，17：	1
8	Lactose metabolism in filamentous fungi: how to deal with an unknown substrate 显示文摘	Bernhard S Babak S P Lukas H	2007	Fungal Biology Reviews2007，21，1：	1
9	In Vivo Enhancement of Tumor Radioresponse by C225 Antiepidermal Growth Factor Receptor Antibody显示文摘	Luka M Kathy M Nancy H	2000	Clin Cancer Res2000，6，2：	1
10	CyclinD1 expression is regulated by the retinoblastoma protein显示文摘	Muller H Lukas J Schneider A	1994	Proc Natl Acad Sci U S A1994，91，8：	1
11	Cyclin D1 protein expression and function in human breast cancer显示文摘	Lukas J Muller H	1994	Int J Cancer1994，57，3：	1
12	Changes in iron-regulatory proteins in the aged rodent neural retina 显示文摘	Chen H Liu B Lukas T J Suyeoka G Wu G Neufeld AH	2008	Neurobiol Aging2008，，：	1
13	Asymmetric Cyclization of 2' -Hydroxychalcones to Flavanones: Catalysis by Ch-Iral Bronsted Acids and Bases显示文摘	CLAUDIA D GERHARD R LUKAS H	2007	Eur J Org Chem2007，，1：	1
14	Development ofa stack simulation model for control study on direct reforming molten carbonate fuel cell power plant显示文摘	Lukas M D Lee K Y Ghezel-Ayagh H	1999	IEEE Transaction on Energy Conversion1999，14，4：	1
15	An explicit dynamic model for direct reforming carbonate fuel cell stack显示文摘	Lukas M D Lee K Y Ghezel-Ayagh H	2001	IEEE Transaction on Energy Conversion2001，16，3：	1
16	Widely tunable torsional optical filter显示文摘	CARLOS F R MATEUS C H C LUKAS C	2002	IEEE Photon Technol Lett2002，14，6：	1
17	Experimental investigation and thermodynamic calculation of the Al-Mg-Zn system 显示文摘	LIANG P TARFA T ROBINSON J A WAGNER S OCHIN P HARMELIN M G SEIFERT H J LUKAS H L ALDINGER F	1998	Thermochimica Acta1998，314，12：	1
18	Investigation of Al-Mg-Si system by experiments and thermodynamic calculations显示文摘	Gdecke T Lukas H L	1997	J Alloys Compounds1997，247，：	1
19	50 years reaction scheme after Erich Scheil显示文摘	Lukas H L Henig E T Petzow G	1986	Z Metallkd1986，77，：	1
20	On the crystal structure and solubility range on the ternary phase in the Mg-Al-Zn system 显示文摘	DONNADIEU P QUIVY A TARFA T OCHIN P DEZELLUS A HARMELIN M G LIANG P LUKAS H L SEIFERT H J ALDINGER F EFFENBERG G	1997	Z Metallkd1997，88，12：	1

返回顶部每页显示：

共8页首页上一页第1页下一页末页 /8 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示