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| 1 | U-Pb Zircon Geochronology and Geochemistry of Granitoids in the Douling Group in the Eastern Qinling显示文摘LA-ICPMS U-Pb zircon dating of the Sanpinggou, Gangou and Fengzishan granitoids in the Douling Group of the Eastern Qinling yields ages of 760-685 Ma, which represents a strong tectono-magmatic event in the southern Qinling during the late Neoproterozoic. Geochemical data show that these intrusions have wide compositions ranging from minor gabbros through diorites to granodiorites. They are relatively enriched in LILE, poor in HFSE and strongly depleted in Nb and Ta, displaying affinities of I-type granites formed in an active continental margin with oceanic subduction. In contrast to granitoids, gabbros and enclaves in the granitoids have higher REE abundances, relatively flat REE patterns, lower LILE, slightly higher HFSE and more depletion in Nb and Ta. All these suggest that the gabbros were formed by partial melting of the upper mantle above the subduction zone and the granitoids by the partial melting of the lower crust. Combined with regional geological data, the subduction-related granitoids in the Douling Group, together with the Tuwushan A-type granite with an age of 725 Ma and contemporaneous basic dikes in the Wudang Block, provide evidence for local subduction of oceanic basins between different blocks during the rifling in the Southern Qinling in the Neoproterozoic. Thus, the coexistences of various magmatic rocks formed in different tectonic environments indicate a complicated tectonic evolution and variety of tectonic frameworks in the Qinling area in the Neoproterozoic. | ZHANGChengli LIMiao WANGTao YUANHonglin YANYunxiang LIUXiaoming WANGJianqi LIUYe | 2004 | Acta Geologica Sinica(English Edition)2004，78，1： | 13 |
| 2 | Flavonoids from Scutellaria barbata inhibit activation of tumor-associated macrophages by blocking the Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB signaling pathway显示文摘OBJECTIVE: To determine the efficacy of Scutellaria barbata flavonoids and polysaccharides on Ishikawa endometrial carcinoma cells co-cultured with U937 macrophages.METHODS: The presence of CD163 and CD206 was determined by flow cytometry. Thiazolyl Blue Tetrazolium Bromide assays were used to assess the proliferation effect of tumor-associated macrophages(TAMs) on Ishikawa cells. The secretion of interleukin(IL)-10 in the co-culture conditioned media was examined using an enzyme-linked immunosorbent assay. The protein expression levels of Toll-like receptor 4(TLR4), myeloid differentiation factor 88(MyD88) and nuclear factor(NF)-κB p65 were detected by Western blot. The mRNA expression levels of TLR4 and MyD88 were analyzed by real-time polymerase chain reaction(PCR). The expression levels of IL-12, IL-1β and tumor necrosis factor-α(TNF-α) were evaluated with real-time PCR.RESULTS: Compared with the U937 control group,the expression levels of CD163 and CD206 in the TAM group were higher(P < 0.05). TAMs co-cultured with Ishikawa cells for 24 or 48 h showed higher proliferation rates(P < 0.05). The expression levels of IL-12 decreased than compared with those in the U937 untreated group(P <0.05) and those of the Scutellaria barbata flavonoids group(P < 0.05). The expression levels of CD206, CD163, IL-10, IL-1β and TNF-α, NF-κB p65 and TLR4/MyD88 in the TAMs control group were greater than those in the U937 untreated group(P < 0.05) and those of the Scutellaria barbata flavonoids group(P < 0.05).CONCLUSION: Scutellaria barbata flavonoids may inhibit TAM activation by blocking the TLR4/MyD88/NF-κB signaling pathway. | Bao Xiaoxia Li Liuye Xue Xiaoou | 2019 | Journal of Traditional Chinese Medicine2019，39，2： | 2 |
| 3 | Element-free Galerkin methods显示文摘 | LiuY Y Gu L | 1994 | International Journal for Numerical Methods in Engineering1994，37，： | 1 |
| 4 | Effect of temperature on the surface free energy of amorphous carbon films显示文摘 | ZhaoQ LiuY Abel E W | 2004 | J Colloid Interface Sci2004，280，1： | 1 |
| 5 | FluorinemediatedphotocatalyticactivityofBiPO4显示文摘 | LiuY LvY ZhuY etal | 2014 | AppliedCatalysisB2014，147，5： | 1 |
| 6 | DegradationandmineralizationmechanismofphenolbyBiPO4 photocatalysisassistedwithH2O2显示文摘 | LiuY ZhuY XuJ etal | 2013 | AppliedCatalysisB2013，，： | 1 |
| 7 | Wound repair by bone marrowstromal cells through growth factor production 显示文摘 | LiuY Dulchavsky DS Gao X | 2006 | J Surg Res2006，136，2： | 1 |
| 8 | 青藏铁路冻土层的相互作用[J]显示文摘 | WuQ LiM LiuY | 2010 | 寒区工程2010，24，4： | 1 |
| 9 | J Org Chem显示文摘 | LiuY Da C S Yu S L | 2010 | 75: 6869-68782010，75，： | 1 |
| 10 | Word of mouth for movies; Its dynamics and impact on box office revenue显示文摘 | LiuY | 2006 | Journal of Marketing2006，70，3： | 1 |
| 11 | Urbanpovertyneighbourhoods:typologyandspatialconc entrationunderChina’smarkettransition,acasestudyofNanjing显示文摘 | LiuY WuF | 2006 | Geoforum2006，37，4： | 1 |
| 12 | Rapid change of AM fungal community in a rain-fed wheat field with short-term plastic film mulching practice显示文摘 | LiuY Mao L He X Cheng G Ma X J An L Z Feng H Y | 2012 | Mycorrhiza2012，22，1： | 1 |
| 13 | Discrepancy measures for selecting optimal combination of parameter values in ob ject-based image analysis 显示文摘 | LIUY BIAN L MENG Y | 2012 | ISPRS Journal of Photogrammetry and Remote Sensing2012，，68： | 1 |
| 14 | Analysis of 310 cases of adverse reactions of Shuanghuanglian Injection[J]显示文摘 | GongT LiuY ZhangBL | 2003 | 天津中医学院学报2003，22，1： | 1 |
| 15 | LaFeyNi1yO3supportednickelcatalystsusedforsteam reformingofethanol显示文摘 | ChenS LiuY | 2009 | InternationalJournalofHydrogenEnergy2009，34，11： | 1 |
| 16 | SteamreformingofethanoloverNi/CexTi1xO2catalysts显示文摘 | YeJ WangY LiuY etal | 2008 | InternationalJournalofHydrogenEnergy2008，33，22： | 1 |
| 17 | Cilostazol as a unique antithrombotic agent显示文摘 | KambayashiJ LiuY SunB etal | 2003 | Curr Pharm Des2003，9，： | 1 |
| 18 | TLR2andTLR4inautoimmunedisease:acomprehensivereview显示文摘 | LiuY YinH ZhaoM etal | 2014 | ClinicRevAllergImmunol2014，47，2： | 1 |
| 19 | As soeiation between cholesterol level and mortality in dialysis patients : role of inflammation and malnutrition 显示文摘 | LiuY Coresh J Eustace J A | 2004 | JAMA2004，291，4： | 1 |
| 20 | Auremicsolute,Pcresol,inhibitstheproliferationofendothelialprogenitorcellsviathep38pathway显示文摘 | YingY YangK LiuY etal | 2011 | CircJ2011，75，9： | 1 |
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