5篇
您的检索式：作者名="LI Longkun"
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| 1 | The female stress urinary incontinence treatment guidelines outline显示文摘 | LI Longkun | 2008 | Chinese Journal of surgery2008，10，20： | 1 |
| 2 | Reverse Mode of the Sodium/Calcium Exchanger Subtype 3 in Interstitial Cells of Cajal From Rat Bladder显示文摘 | Xiao Zhong Jianping Deng Peng He Nan You Qingqing Wang Bo Song Longkun Li | 2013 | Urology2013，，1： | 1 |
| 3 | Identification of T-type Calcium Channels in the Interstitial Cells of Cajal in Rat Bladder显示文摘 | Jianping Deng Peng He Xiao Zhong Qingqing Wang Longkun Li Bo Song | 2012 | Urology2012，，6： | 1 |
| 4 | PD-1/L1 inhibitors can improve but not replace chemotherapy for advanced urothelial carcinoma:A systematic review and network meta-analysis显示文摘Background:Programmed cell death-1/ligand 1 inhibitors are a new treatment strategy for advanced urothelial carcinoma.Therefore,a comparative evaluation of their efficacy and toxicity compared with chemotherapy is necessary.Methods:We comprehensively searched PubMed,Web of Science,Embase,and Cochrane Library databases and performed a meta-analysis of randomized controlled trials up to July 2021.We considered overall survival as the primary outcome,and progression-free survival,objective response rate,and treatment-related adverse events as secondary outcomes.Results:Overall,3584 patients from five studies were evaluated.Compared with first-line chemotherapy,programmed cell death-1/ligand 1 inhibitors were significantly associated with worse progression-free survival(p<0.001)and adverse objective response rates(p<0.001).However,the treatments were not significantly different in terms of overall survival(p=0.33).Compared with second-line chemotherapy,programmed cell death-1/ligand 1 inhibitors significantly improved overall survival(p<0.001),and there was no statistically significant difference in progression-free survival(p=0.89)or objective response rate(p=0.34).Compared with chemotherapy,programmed cell death-1/ligand 1 inhibitors were well tolerated(first-line chemotherapy:p<0.001;second-line chemotherapy:p<0.001).Conclusions:The efficacy of programmed cell death-1/ligand 1 inhibitors in patients with advanced urothelial carcinoma is not superior to that of first-line platinum-based chemotherapy but is better than second-line chemotherapy;however,programmed cell death-1/ligand 1 inhibitors are safer than first-and second-line chemotherapy and have a broader prospect for use in combination therapy. | Longkun Mao Meihua Yang Xinxiang Fan Wenjie Li Xiaodong Huang Wang He Tianxin Lin Jian Huang | 2023 | Cancer Innovation2023，2，3： | 0 |
| 5 | Viologens-based redox mediators with tunable HOMO–LUMO energy gap for highly effective hydrogen peroxide electrosynthesis显示文摘In comparison with the developing nano-carbon catalysts,some small organic molecules are also emerging as catalysts with typical features,however,their working mechanism is still unclear.Here,we synthesized a series of viologen-based heterogeneous catalysts with the same molecular skeleton but different substituent groups through anion exchange engineering.These viologen-based molecules were used as a model catalyst to investigate the underlying structure–function relationship for small molecules-based H_(2)O_(2) electrosynthesis.Differing from the commonly reported carbon-based electrocatalysts,viologens can produce H_(2)O_(2) in a synergistic manner,which means that viologens can not only directly catalyze oxygen reduction but also serve as a redox mediator.We found that the ring current and H_(2)O_(2) selectivity of viologens deliver an increasing trend with the increase of the alkyl chain length of alkyl-substituted viologens and further increase when using benzyl as the substituent group.As a result,a benzyl-substituted viologen(BV)delivers the best electrocatalytic performance among the samples,including the highest H_(2)O_(2) selectivity of 96.9%at 0.6 V and the largest ring current density of about 13.6 mA·mmol-1.Furthermore,density functional theory(DFT)calculations disclose that the carbon atoms bonded with positively charged N are the active sites and the small highest occupied molecular orbital(HOMO)–lowest unoccupied molecular orbital(LUMO)energy gap of BV is beneficial to the synergistic mechanism for H_(2)O_(2) production.This work sheds new insight into the efficient H_(2)O_(2) production in a synergistic manner for small molecules-based electrocatalysts. | Yang Gao Xiaohui Xu Yue Niu Xinran Hu Zeyu Li Longkun Yang Linjie Zhi Bin Wang | 2023 | Nano Research2023，16，12： | 0 |
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